Circulating monocytes and cardiac macrophages in diastolic dysfunction (Mus musculus)

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1Endothelial cellMacrophageLeft ventriculardiastolic dysfunctionBloodCollagen depositionAutocrine activationDecreased proteases / MMPsCcl2ROSIl10Spp1MyofibroblastFibroblastROSROSIl10MonocyteFibroblastactivationMyocardiumMonocyteCcr2Adhesionmolecules


Description

draft

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Quality Tags

Ontology Terms

 

Bibliography

  1. Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M; ''Cardiac macrophages promote diastolic dysfunction.''; J Exp Med, 2018 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
129333view09:07, 27 March 2024MkutmonOntology Term : 'disease pathway' added !
102094view00:18, 29 November 2018KhanspersModified title
102093view00:14, 29 November 2018KhanspersModified description
102091view22:14, 28 November 2018KhanspersOntology Term : 'hypertension' added !
102090view22:14, 28 November 2018KhanspersOntology Term : 'myofibroblast cell' added !
102089view22:13, 28 November 2018KhanspersOntology Term : 'cardiovascular system disease' added !
102088view22:13, 28 November 2018KhanspersOntology Term : 'macrophage' added !
102087view22:13, 28 November 2018KhanspersOntology Term : 'monocyte' added !
102086view22:12, 28 November 2018KhanspersNew pathway

External references

DataNodes

NameTypeDatabase referenceComment
Ccl2GeneProductENSMUSG00000035385 (Ensembl)
Ccr2GeneProductENSMUSG00000049103 (Ensembl)
Il10GeneProductENSMUSG00000016529 (Ensembl)
ROSMetaboliteCHEBI:26523 (ChEBI)
Spp1GeneProductENSMUSG00000029304 (Ensembl)

Annotated Interactions

No annotated interactions

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