Glucosinolate biosynthesis from methionine (Arabidopsis thaliana)
From WikiPathways
Description
This pathway describes the glucosinolate derived from methionine in Arabidopsis thaliana. This is based on the KEGG pathway and PlantCyc.
Some pathway entities are unknown and being investigated, these are denoted as "Catalyst" and "Metabolite" for now.
Quality Tags
Ontology Terms
Bibliography
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- Grubb CD, Zipp BJ, Ludwig-Mテシller J, Masuno MN, Molinski TF, Abel S; ''Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis.''; Plant J, 2004 PubMed Europe PMC Scholia
- Wittstock U, Burow M; ''Glucosinolate breakdown in Arabidopsis: mechanism, regulation and biological significance.''; Arabidopsis Book, 2010 PubMed Europe PMC Scholia
- Piotrowski M, Schemenewitz A, Lopukhina A, Mテシller A, Janowitz T, Weiler EW, Oecking C; ''Desulfoglucosinolate sulfotransferases from Arabidopsis thaliana catalyze the final step in the biosynthesis of the glucosinolate core structure.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
- Textor S, Bartram S, Kroymann J, Falk KL, Hick A, Pickett JA, Gershenzon J; ''Biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana: recombinant expression and characterization of methylthioalkylmalate synthase, the condensing enzyme of the chain-elongation cycle.''; Planta, 2004 PubMed Europe PMC Scholia
- Klein M, Reichelt M, Gershenzon J, Papenbrock J; ''The three desulfoglucosinolate sulfotransferase proteins in Arabidopsis have different substrate specificities and are differentially expressed.''; FEBS J, 2006 PubMed Europe PMC Scholia
- Textor S, de Kraker JW, Hause B, Gershenzon J, Tokuhisa JG; ''MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis.''; Plant Physiol, 2007 PubMed Europe PMC Scholia
- Knill T, Reichelt M, Paetz C, Gershenzon J, Binder S; ''Arabidopsis thaliana encodes a bacterial-type heterodimeric isopropylmalate isomerase involved in both Leu biosynthesis and the Met chain elongation pathway of glucosinolate formation.''; Plant Mol Biol, 2009 PubMed Europe PMC Scholia
- Klein M, Papenbrock J; ''Kinetics and substrate specificities of desulfo-glucosinolate sulfotransferases in Arabidopsis thaliana.''; Physiol Plant, 2009 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
3-Benzoyloxypropyl-glucosinolate | Metabolite | C00007358 (KNApSAcK) | |
2-(2'-Methylthio)ethylmalic acid | Metabolite | C17210 (KEGG Compound) | |
2-(3'-Methylthio)propylmalic acid | Metabolite | C17214 (KEGG Compound) | |
2-(4'-Methylthio)butylmalic acid | Metabolite | C17218 (KEGG Compound) | |
2-(5'-Methylthio)pentylmalic acid | Metabolite | C17222 (KEGG Compound) | |
2-(6'-Methylthio)hexylmalic acid | Metabolite | C17226 (KEGG Compound) | |
2-(7'-Methylthio)heptylmalic acid | Metabolite | C17230 (KEGG Compound) | |
2-(Methylsulfinyl)ethyl-glucosinolate | Metabolite | ||
2-Benzoyloxy-3-butenyl glucosinolate | Metabolite | 90657992 (PubChem-compound) | |
2-Hydroxy 3-butenyl glucosinolate | Metabolite | C00001486 (KNApSAcK) | |
2-Oxo-10-methylthiodecanoic acid | Metabolite | C17232 (KEGG Compound) | |
2-Oxo-4-methylthiobutanoic acid | Metabolite | HMDB01553 (HMDB) | |
2-Oxo-5-methylthiopentanoic acid | Metabolite | CHEBI:50260 (ChEBI) | |
2-Oxo-6-methylthiopentanoic acid | Metabolite | C17216 (KEGG Compound) | |
2-Oxo-7-methylthioheptanoic acid | Metabolite | C17220 (KEGG Compound) | |
2-Oxo-8-methylthiooctanoic acid | Metabolite | C17224 (KEGG Compound) | |
2-Oxo-9-methylthiononanoic acid | Metabolite | C17228 (KEGG Compound) | |
2-Propenyl glucosinolate | Metabolite | CHEBI:79317 (ChEBI) | |
2-Sinapoyloxy-3-butenyl glucosinolate | Metabolite | 90658722 (PubChem-compound) | |
3-(2'-Methylthio)ethylmalic acid | Metabolite | C17212 (KEGG Compound) | |
3-(3'-Methylthio)propylmalic acid | Metabolite | C17215 (KEGG Compound) | |
3-(4'-Methylthio)butylmalic acid | Metabolite | C17219 (KEGG Compound) | |
3-(5'-Methylthio)pentylmalic acid | Metabolite | C17223 (KEGG Compound) | |
3-(6'-Methylthio)hexylmalic acid | Metabolite | C17227 (KEGG Compound) | |
3-(7'-Methylthio)heptylmalic acid | Metabolite | C17231 (KEGG Compound) | |
3-(Methylsulfinyl)propyl-glucosinolate | Metabolite | CHEBI:5406 (ChEBI) | |
3-Butenyl glucosinolate | Metabolite | C00007586 (KNApSAcK) | |
3-Hydroxypropyl-glucosinolate | Metabolite | C00007340 (KNApSAcK) | |
3-Methylthiopropyl glucosinolate | Metabolite | CHEBI:79326 (ChEBI) | |
3-Methylthiopropyl-desulfoglucosinolate | Metabolite | C17244 (KEGG Compound) | |
3-Sinapoyloxypropyl-glucosinolate | Metabolite | 90657803 (PubChem-compound) | |
4-(Methylsulfinyl)butyl glucosinolate | Metabolite | C00007545 (KNApSAcK) | |
4-Benzoyloxybutyl glucosinolate | Metabolite | C00007359 (KNApSAcK) | |
4-Hydroxybutyl-glucosinolate | Metabolite | C00007342 (KNApSAcK) | |
4-Methylthiobutanaldoxime | Metabolite | C17241 (KEGG Compound) | |
4-Methylthiobutyl glucosinolate | Metabolite | C08409 (KEGG Compound) | |
4-Methylthiobutyl-desulfoglucosinolate | Metabolite | C17248 (KEGG Compound) | |
4-Methylthiobutylthiohydroximate | Metabolite | CHEBI:80984 (ChEBI) | |
4-Pentenyl glucosinolate | Metabolite | CHEBI:79318 (ChEBI) | |
4-Sinapoyloxybutyl-glucosinolate | Metabolite | 46173533 (PubChem-compound) | |
5-(Methylsulfinyl)pentyl glucosinolate | Metabolite | C00007345 (KNApSAcK) | |
5-Methylthiopentanaldoxime | Metabolite | C17241 (KEGG Compound) | |
5-Methylthiopentyl glucosinolate | Metabolite | C08401 (KEGG Compound) | |
6-(Methylsulfinyl)hexyl glucosinolate | Metabolite | C00007348 (KNApSAcK) | |
6-Methylthiohexanaldoxime | Metabolite | C17246 (KEGG Compound) | |
6-Methylthiohexyl glucosinolate | Metabolite | C17250 (KEGG Compound) | |
7-(Methylsulfinyl)heptyl glucosinolate | Metabolite | C00007352 (KNApSAcK) | |
7-Methylthioheptanaldoxime | Metabolite | C17249 (KEGG Compound) | |
7-Methylthioheptyl glucosinolate | Metabolite | C17252 (KEGG Compound) | |
7-Methylthioheptyl-desulfoglucosinolate | Metabolite | C21650 (KEGG Compound) | |
8-(Methylsulfinyl)octyl glucosinolate | Metabolite | C00007355 (KNApSAcK) | |
8-Methylthiooctanaldoxime | Metabolite | C17251 (KEGG Compound) | |
8-Methylthiooctyl glucosinolate | Metabolite | C17254 (KEGG Compound) | |
8-Methylthiooctyl-desulfoglucosinolate | Metabolite | C21746 (KEGG Compound) | |
9-(Methylsulfinyl)nonyl glucosinolate | Metabolite | C00007832 (KNApSAcK) | |
9-Methylthiononanaldoxime | Metabolite | C17253 (KEGG Compound) | |
BCAT3 | GeneProduct | AT3G49680 (TAIR) | |
BCAT4 | GeneProduct | AT3G19710 (TAIR) | |
CYP79F1 | GeneProduct | AT1G16410.1 (TAIR) | |
CYP79F2 | GeneProduct | AT1G16400 (TAIR) | |
CYP83A1 | GeneProduct | AT4G13770 (TAIR) | |
Catalyst | GeneProduct | ||
Dihomomethionine | Metabolite | C17217 (KEGG Compound) | |
Hexahomomethionine | Metabolite | C17233 (KEGG Compound) | |
Homomethionine | Metabolite | C17213 (KEGG Compound) | |
IIL1 | GeneProduct | AT4G13430 (TAIR) | |
IMD1 | GeneProduct | AT5G14200 (TAIR) | |
IMS2 | GeneProduct | AT5G23020 (TAIR) | |
IPMI1 | GeneProduct | AT3G58990 (TAIR) | |
IPMI2 | GeneProduct | AT2G43100 (TAIR) | |
MAM1 | GeneProduct | AT5G23010 (TAIR) | |
Metabolite | Metabolite | ||
Methionine | Metabolite | C00001379 (KNApSAcK) | |
Pentahomomethionine | Metabolite | C17229 (KEGG Compound) | |
S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine | Metabolite | C17242 (KEGG Compound) | |
SOT16 | GeneProduct | AT1G74100 (TAIR) | |
SOT17 | GeneProduct | AT1G18590 (TAIR) | |
SOT18 | GeneProduct | AT1G74090 (TAIR) | |
SUR1 | GeneProduct | AT2G20610 (TAIR) | |
Tetrahomomethionine | Metabolite | C17225 (KEGG Compound) | |
Trihomomethionine | Metabolite | C17221 (KEGG Compound) | |
UGT74B1 | GeneProduct | AT1G24100 (TAIR) |
Annotated Interactions
No annotated interactions