Macrophage markers (Homo sapiens)

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Immune cell specific expression(based on GeneAtlas)CD83CD141, 5CD683F3CD1632CD866-8CD74Cd52RAC2LYZMacrophage markers4


Description

Overview of macrophage markers. Based on this list and tissue-specific gene expression from GeneAtlas. This pathway is part the CPTAC Assay Portal.

Comments

HomologyMapper 
This pathway was inferred from Mus musculus pathway WP2271 (rev 69962) with a 90.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

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  1. Brettschneider J, Ecker D, Bitsch A, Bahner D, Bogumil T, Dressel A, Elitok E, Kitze B, Poser S, Weber F, Tumani H; ''The macrophage activity marker sCD14 is increased in patients with multiple sclerosis and upregulated by interferon beta-1b.''; J Neuroimmunol, 2002 PubMed Europe PMC Scholia
  2. Töröcsik D, Bárdos H, Nagy L, Adány R; ''Identification of factor XIII-A as a marker of alternative macrophage activation.''; Cell Mol Life Sci, 2005 PubMed Europe PMC Scholia
  3. Kunz-Schughart LA, Weber A, Rehli M, Gottfried E, Brockhoff G, Krause SW, Andreesen R, Kreutz M; ''[The "classical" macrophage marker CD68 is strongly expressed in primary human fibroblasts].''; Verh Dtsch Ges Pathol, 2003 PubMed Europe PMC Scholia
  4. Aperlo C, Sevilla L, Guerin S, Pognonec P, Boulukos KE; ''Synergistic effects of colony-stimulating factor 1 and leukemia inhibitory factor in inducing early myeloid cell differentiation.''; Cell Growth Differ, 1998 PubMed Europe PMC Scholia
  5. Mahnke K, Becher E, Ricciardi-Castagnoli P, Luger TA, Schwarz T, Grabbe S; ''CD14 is expressed by subsets of murine dendritic cells and upregulated by lipopolysaccharide.''; Adv Exp Med Biol, 1997 PubMed Europe PMC Scholia
  6. Lau SK, Chu PG, Weiss LM; ''CD163: a specific marker of macrophages in paraffin-embedded tissue samples.''; Am J Clin Pathol, 2004 PubMed Europe PMC Scholia
  7. Hiraoka A, Horiike N, Akbar SM, Michitaka K, Matsuyama T, Onji M; ''Expression of CD163 in the liver of patients with viral hepatitis.''; Pathol Res Pract, 2005 PubMed Europe PMC Scholia
  8. Fonseca JE, Edwards JC, Blades S, Goulding NJ; ''Macrophage subpopulations in rheumatoid synovium: reduced CD163 expression in CD4+ T lymphocyte-rich microenvironments.''; Arthritis Rheum, 2002 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
107552view23:36, 19 October 2019AlexanderPicoModified description
106639view21:02, 12 September 2019KhanspersModified description
105642view05:08, 10 August 2019KhanspersModified description
94392view12:26, 6 September 2017MkutmonOntology Term : 'macrophage' added !
94391view12:25, 6 September 2017MkutmonNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CD14GeneProductENSG00000170458 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12475
CD163GeneProductENSG00000177575 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:93671
CD68GeneProductENSG00000129226 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12514
CD74GeneProductENSG00000019582 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16149
CD83GeneProductENSG00000112149 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12522
CD86GeneProductENSG00000114013 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12524
Cd52GeneProductNo homologues found for original id L:23833
F3GeneProductENSG00000117525 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14066
LYZGeneProductENSG00000090382 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17105
RAC2GeneProductENSG00000128340 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19354

Annotated Interactions

No annotated interactions
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