G13 signaling (Homo sapiens)
From WikiPathways
Description
The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells.
Source: Wikipedia
Proteins on this pathway have targeted assays available via the CPTAC Assay PortalQuality Tags
Ontology Terms
Bibliography
- Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
ARHGDIB | GeneProduct | 397 (Entrez Gene) | |
ARHGDIG | GeneProduct | 398 (Entrez Gene) | |
ARHGEF1 | GeneProduct | 9138 (Entrez Gene) | |
CALM1 | GeneProduct | 801 (Entrez Gene) | |
CDC42 | GeneProduct | 998 (Entrez Gene) | |
CFL1 | GeneProduct | 1072 (Entrez Gene) | |
CFL2 | GeneProduct | 1073 (Entrez Gene) | |
CIT | GeneProduct | 11113 (Entrez Gene) | |
CYFIP1 | GeneProduct | 23191 (Entrez Gene) | |
DIAPH1 | GeneProduct | 1729 (Entrez Gene) | |
GNA13 | GeneProduct | 10672 (Entrez Gene) | |
IQGAP1 | GeneProduct | 8826 (Entrez Gene) | |
IQGAP2 | GeneProduct | 10788 (Entrez Gene) | |
LIMK1 | GeneProduct | 3984 (Entrez Gene) | |
MAP3K4 | GeneProduct | 4216 (Entrez Gene) | |
MAPK10 | GeneProduct | 5602 (Entrez Gene) | |
MYBPH | GeneProduct | 4608 (Entrez Gene) | |
MYL1 | GeneProduct | 4632 (Entrez Gene) | |
PAK3 | GeneProduct | 5063 (Entrez Gene) | |
PFN1 | GeneProduct | 5216 (Entrez Gene) | |
PIK3CA | GeneProduct | 5290 (Entrez Gene) | |
PIK3CB | GeneProduct | 5291 (Entrez Gene) | |
PIK3CD | GeneProduct | 5293 (Entrez Gene) | P42338 |
PIK3R2 | GeneProduct | 5296 (Entrez Gene) | |
PIP5K2A | GeneProduct | 5305 (Entrez Gene) | |
PKN1 | GeneProduct | 5585 (Entrez Gene) | |
PPP1CB | GeneProduct | 5500 (Entrez Gene) | |
RAC1 | GeneProduct | 5879 (Entrez Gene) | |
RHOA | GeneProduct | 387 (Entrez Gene) | |
RHPN2 | GeneProduct | 85415 (Entrez Gene) | |
ROCK1 | GeneProduct | 6093 (Entrez Gene) | S69211 |
ROCK2 | GeneProduct | 9475 (Entrez Gene) | BAA31594 |
RPS6KB1 | GeneProduct | 6198 (Entrez Gene) | A41687 |
RTKN | GeneProduct | 6242 (Entrez Gene) | |
SH3MD2 | GeneProduct | 57630 (Entrez Gene) | Posh |
TNK2 | GeneProduct | 10188 (Entrez Gene) | S33596 |
WAS | GeneProduct | 7454 (Entrez Gene) | |
WASL | GeneProduct | 8976 (Entrez Gene) |
Annotated Interactions
No annotated interactions