IL-5 signaling pathway (Danio rerio)

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ControlExtracellularDDGene SymbolCY->MTPhosphorylationProteins in a complex interactionTranslocationPM->NUPM->NUAutophosphorylationEndoplasmic reticulumAcetylationPlasma membraneECDCY->NULigandDeacetylationRecruitmentEndosomeDGlycosylationMTDEnzyme complexMitochondriaCytoplasmPMNUGolgi apparatusReaction through unknown mechanisms/moleculesProteolytic cleavageMolecule in the pathwayPM->NUUbiquitinationDMolecular associationDephosphorylationDDDERCY->PMInhibitionDDAccession Number: NetPath 17DActivationDeubiquitinationPalmitoylationDCY->NUDNucleusDesumoylationDReceptorGOCYMethylationDDemethylationCY->NUENDD(Protein-protein interaction)SumoylationbtkSTAT5Bpik3r2IL5RALOC569951mapk14ajak1PRKCDdnm2lgsk3bLOC792354crklICAM1sykfoxo5CSF2RBIL2RBcdkn1bkrasVAV1ptpn6ctnnb1ptpn11PRKCDSTAT5Ajuncblsi:dkey-94n12.3STAT5ADKEY-194N13.2LOC791800zgc:153997LOC563639UNC119PLA2G4AcrklYWHAZLOC567895prkcb1sdcbpITGAMzgc:172250DKEY-194N13.2CH211-127H20.2GSK3Azgc:77033LOC100149273jak2bSTAT5BNFKB1NFKB1LOC560525ICAM3NFKBIAmapk3LOC557176rac1BAXzgc:92124CCND3zgc:175180stat3IL5LOC557797ptk2bbHRASIL5RAatf2lsocs1CSF2RBraf1IL5ctnnb1BAXstat1aHCLS1mapk1grb2rps6ka3aSOX4CSF2RB


Description

No description

Comments

GenMAPP notes 
NetPath 17 - IL-5 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP127(r20949) with a 61% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
116886view11:07, 15 May 2021EweitzModified title
86934view13:06, 15 July 2016MkutmonOntology Term : 'interleukin-5 signaling pathway' added !
68639view04:52, 6 July 2013MaintBotUpdated to 2013 gpml schema
40806view22:16, 1 March 2011MaintBotRemoved redundant pathway information and comments
34195view21:26, 9 December 2009MaintBotAutomatic update of empty xrefs
31345view20:28, 13 August 2009MaintBotFixed text labels
31025view01:11, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
BAXGeneProduct
CCND3GeneProduct
CH211-127H20.2GeneProduct558635 (Entrez Gene)
CSF2RBGeneProduct100135062 (Entrez Gene)
DKEY-194N13.2GeneProduct567204 (Entrez Gene)
GSK3AGeneProduct30664 (Entrez Gene)
HCLS1GeneProduct
HRASGeneProduct550286 (Entrez Gene)
ICAM1GeneProduct
ICAM3GeneProduct
IL2RBGeneProduct793920 (Entrez Gene)
IL5GeneProduct
IL5RAGeneProduct
ITGAMGeneProduct
LOC100149273GeneProduct100149273 (Entrez Gene)
LOC557176GeneProduct557176 (Entrez Gene)
LOC557797GeneProduct557797 (Entrez Gene)
LOC560525GeneProduct560525 (Entrez Gene)
LOC563639GeneProduct563639 (Entrez Gene)
LOC567895GeneProduct567895 (Entrez Gene)
LOC569951GeneProduct569951 (Entrez Gene)
LOC791800GeneProduct791800 (Entrez Gene)
LOC792354GeneProduct792354 (Entrez Gene)
NFKB1GeneProduct565756 (Entrez Gene)
NFKBIAGeneProduct
PLA2G4AGeneProduct559087 (Entrez Gene)
PRKCDGeneProduct334571 (Entrez Gene)
SOX4GeneProduct
STAT5AGeneProduct
STAT5BGeneProduct
UNC119GeneProduct
VAV1GeneProduct
YWHAZGeneProduct
atf2lGeneProduct100006516 (Entrez Gene)
btkGeneProduct568653 (Entrez Gene)
cblGeneProduct492364 (Entrez Gene)
cdkn1bGeneProduct368329 (Entrez Gene)
crklGeneProduct556443 (Entrez Gene)
ctnnb1GeneProduct30265 (Entrez Gene)
dnm2lGeneProduct406525 (Entrez Gene)
foxo5GeneProduct30296 (Entrez Gene)
grb2GeneProduct406308 (Entrez Gene)
gsk3bGeneProduct30654 (Entrez Gene)
jak1GeneProduct30280 (Entrez Gene)
jak2bGeneProduct30298 (Entrez Gene)
junGeneProduct335916 (Entrez Gene)
krasGeneProduct445289 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mapk14aGeneProduct65237 (Entrez Gene)
mapk3GeneProduct399480 (Entrez Gene)
pik3r2GeneProduct404211 (Entrez Gene)
prkcb1GeneProduct393953 (Entrez Gene)
ptk2bbGeneProduct245950 (Entrez Gene)
ptpn11GeneProduct333979 (Entrez Gene)
ptpn6GeneProduct335573 (Entrez Gene)
rac1GeneProduct327204 (Entrez Gene)
raf1GeneProduct30716 (Entrez Gene)
rps6ka3aGeneProduct338219 (Entrez Gene)
sdcbpGeneProduct325004 (Entrez Gene)
si:dkey-94n12.3GeneProduct562011 (Entrez Gene)
socs1GeneProduct445073 (Entrez Gene)
stat1aGeneProduct30768 (Entrez Gene)
stat3GeneProduct30767 (Entrez Gene)
sykGeneProduct405769 (Entrez Gene)
zgc:153997GeneProduct572469 (Entrez Gene)
zgc:172250GeneProduct100002225 (Entrez Gene)
zgc:175180GeneProduct100144557 (Entrez Gene)
zgc:77033GeneProduct406598 (Entrez Gene)
zgc:92124GeneProduct447804 (Entrez Gene)

Annotated Interactions

No annotated interactions
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