G13 signaling pathway (Pan troglodytes)

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1Actin PolymerizationFilopodia FormationContraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber ContractionMembrane RufflingAnti-Apoptotic13Activated Rho AStress FiberDisappearanceActin PolymerizationGDisassembly of ActinActin ReorganizationCell-Cell AdhesionCytokinesisIQGAP2MYBPHARHGEF1RPS6KB1RAC1IQGAP1PIK3CBRTKNPIK3CASH3RF1CYFIP1LIMK1CDC42RHPN2MAP3K4ARHGDIBWASPIK3CDDIAPH1TNK2CITPKN1PIK3R2PFN1ROCK2CALM1ROCK1ARHGDIGGNA13CFL2PAK3CFL1RHOAMYL1MAPK10PPP1CBWASLPIP4K2A


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP524 (r95116) with a 100.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117394view10:34, 21 May 2021EweitzModified title
95756view14:07, 19 January 2018MkutmonHomology conversion update
72020view12:40, 24 October 2013Mkutmonfixed unconnected lines
71676view19:41, 17 October 2013MaintBotAutomated update of data sources
69269view18:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
67279view10:30, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
62741view03:34, 2 May 2013MaintBotUpdated UniProt data source
41577view02:00, 2 March 2011MaintBotRemoved redundant pathway information and comments
35419view10:42, 12 February 2010ThomasModified description
35418view10:39, 12 February 2010Thomasremoved braces, fixed labels, added literature
34305view22:06, 9 December 2009MaintBotAutomatic update of empty xrefs
33595view09:55, 1 December 2009MaintBotRemoved group label
32477view17:40, 15 August 2009MaintBotFixed text labels
31615view22:16, 13 August 2009MaintBotFixed text labels
30514view21:47, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGDIBGeneProductENSPTRG00000004729 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:397
ARHGDIGGeneProductENSPTRG00000031322 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:398
ARHGEF1GeneProductENSPTRG00000011039 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:9138
CALM1GeneProductENSPTRG00000050292 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:801
CDC42GeneProductENSPTRG00000051031 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:998
CFL1GeneProductENSPTRG00000046419 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:1072
CFL2GeneProductENSPTRG00000006254 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:1073
CITGeneProductENSPTRG00000005521 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:11113
CYFIP1GeneProductENSPTRG00000006818 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:23191
DIAPH1GeneProductENSPTRG00000045831 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:1729
GNA13GeneProductENSPTRG00000009551 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:10672
IQGAP1GeneProductENSPTRG00000007455 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:8826
IQGAP2GeneProductENSPTRG00000017002 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:10788
LIMK1GeneProductENSPTRG00000045946 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:3984
MAP3K4GeneProductENSPTRG00000046415 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:4216
MAPK10GeneProductENSPTRG00000016244 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5602
MYBPHGeneProductENSPTRG00000001868 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:4608
MYL1GeneProductENSPTRG00000012879 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:4632
PAK3GeneProductENSPTRG00000022187 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5063
PFN1GeneProductENSPTRG00000008616 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5216
PIK3CAGeneProductENSPTRG00000015642 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5290
PIK3CBGeneProductENSPTRG00000015452 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5291
PIK3CDGeneProductENSPTRG00000000120 (Ensembl)
  • P42338
  • Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5293
PIK3R2GeneProductENSPTRG00000010694 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5296
PIP4K2AGeneProductENSPTRG00000002355 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5305
PKN1GeneProductENSPTRG00000010591 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5585
PPP1CBGeneProductENSPTRG00000011788 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5500
RAC1GeneProductENSPTRG00000052694 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5879
RHOAGeneProductENSPTRG00000014922 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:387
RHPN2GeneProductENSPTRG00000010801 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:85415
ROCK1GeneProductENSPTRG00000009904 (Ensembl)
  • S69211
  • Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:6093
ROCK2GeneProductENSPTRG00000011658 (Ensembl)
  • BAA31594
  • Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:9475
RPS6KB1GeneProductENSPTRG00000009477 (Ensembl)
  • A41687
  • Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:6198
RTKNGeneProductENSPTRG00000012086 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:6242
SH3RF1GeneProductENSPTRG00000016587 (Ensembl)
  • Posh
  • Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:57630
TNK2GeneProductENSPTRG00000049620 (Ensembl)
  • S33596
  • Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:10188
WASGeneProductENSPTRG00000050143 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:7454
WASLGeneProductENSPTRG00000019640 (Ensembl) Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:8976

Annotated Interactions

No annotated interactions
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