Canonical wnt signaling (Danio rerio)

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1fgfnoncanonocal wnt / cytoskeletonmouse developmentxenopustranscriptiondrosophillanot the wnt-homepageBMPzebrafishtumorsmouse (cells)wnt-homepagehuman colon cancernodalvegfcspry2rhoua /wrch1camk1gLRP5rac1sfzd1edabirc5bruvbl2 / reptinc-mycsall4camk2dsqtsfrp2groucho2smobmp2bubxd1RA receptor gcyclinD1fgf3dlafz12jagged 1actnnb1otx1sp5lirx3bfzd10rfzd8bbozccnd1sp5fzd8abeta-catenin1ntlgsk3brac3runx2bdrl / rykpontin52 / ruvbl1wif1ctbp2lNLKE-cadherinNLKck2bCBP / p300dact1 / dapper1hoxb1bCKI-alphalefctbp1sox2sfrp2lcdc42ltcf3b / tcf7l1bcdx1afrzbfibronectin 1lef1sfrp2APCpeawnt8bfzd7adkk1beta-catenin2irx3abeta-catenin1twistdact2 / drappergscsfrp1aprkcb1fzd8cfgf18vedfgf4wnt8aE12 / tcf3fgf18llim1tcf-1 / elk4Tak1sox9atcf4spry4cdc42engrailed 1bfzd9fgf20bmycachdbmp4gata2runx2awisp2RhoAcnos2catenin-beta 1id2abirc5atcf1wnt16foxN1beta-catenin2egfrephrin B1metctbp2sfrp5RhoAafzd3pitx2atclwnt2wnt10bbeta-catenin2PKCdvl3voxck2a1ctnnb2dab2pitx2bcdx4fibronectin 1baxin2engrailed 1amkp3dvl2wnt7GBPfzd1wnt4boepRhoAbcspg2a /versicanRhoAdmitfaeve1fzd4stripe / egr2brac2connexin 43wnt11rotx2sox17axin1nkd1wnt11engrailed 2aRhoAetcf3 / tcf7l1awnt1cdc42l2ldlrpar1bglapptgs2wnt2bfgf20aicatikbkg / nemogroucho1cdh1 / E-cadherinfzd2jagged 1bneurogenin 1wnt10aaxin2 / conductinwnt4ack2a2dldwnt7aprkcb1lfollistatinwnt5bid2bermendothelin 1c-junfgf8VEGFaprkciengrailed 2bfzd7bsmarca4sfzd5ppp2r5e2dact2 / dapper2periostinventsox9bgroucho3prkcl2ppp2r5e1wnt3l


Description

This pathway describes canonical wnt signaling in zebrafish (Danio rerio).

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Quality Tags

Ontology Terms

 

Bibliography

  1. S.F. Gabby Krens, Maximiliano Corredor-Adámez, Shuning He, B. Ewa Snaar- Jagalska, Herman P Spaink; ''ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis''; BMC Genomics 2008, 9:196 , 2008 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118436view14:42, 27 May 2021EgonwReplaced the remaining UniGene IDs
118422view14:21, 27 May 2021EgonwAnother batch
118403view14:11, 27 May 2021EgonwFixed an author name
118400view14:10, 27 May 2021EgonwA bunch more UniGene conversions
118378view13:52, 27 May 2021EgonwMore UniGene replacements
118361view13:42, 27 May 2021EgonwReplaced the first few UniGene IDs
96484view16:23, 15 March 2018Fehrhartfixed some connections
96481view16:20, 15 March 2018FehrhartModified description
95726view20:31, 18 January 2018AlexanderPicoupdated retired unigene id
95725view20:31, 18 January 2018AlexanderPicofixed xref
95724view20:30, 18 January 2018AlexanderPicofixed xref
95723view20:28, 18 January 2018AlexanderPicofixed xref
95722view20:26, 18 January 2018AlexanderPicofixed xref
95721view20:25, 18 January 2018AlexanderPicofixed xref
95720view20:24, 18 January 2018AlexanderPicofixed xref
95719view20:22, 18 January 2018AlexanderPicofixed xref
95718view20:21, 18 January 2018AlexanderPicofixed xref
95717view20:20, 18 January 2018AlexanderPicofixed xref
95716view20:19, 18 January 2018AlexanderPicofixed xref
95715view20:18, 18 January 2018AlexanderPicofixed xref
95714view20:17, 18 January 2018AlexanderPicofixed xref
95713view20:16, 18 January 2018AlexanderPicofixed xref
95712view20:15, 18 January 2018AlexanderPicofixed xref
95711view20:13, 18 January 2018AlexanderPicoupdated retired unigene id
95710view20:11, 18 January 2018AlexanderPicofixed xref
95709view20:10, 18 January 2018AlexanderPicoupdated retired unigene id
95708view20:08, 18 January 2018AlexanderPicofixed xref
95707view20:07, 18 January 2018AlexanderPicofixed xref
95706view20:06, 18 January 2018AlexanderPicofixed xref
95705view20:05, 18 January 2018AlexanderPicofixed xref
95704view20:03, 18 January 2018AlexanderPicofixed xref
95703view20:02, 18 January 2018AlexanderPicoRemoved stray characters and updated xref
74475view04:40, 25 April 2014EgonwFixed a PubMed ID.
71977view00:26, 24 October 2013MaintBotremoved data source from nodes without identifier
70150view21:36, 12 July 2013MaintBotupdated to 2013 schema
70149view21:35, 12 July 2013MaintBotModified title
70077view09:30, 12 July 2013Mkutmonfixed unconnected lines
67098view10:06, 26 June 2013Christine ChichesterOntology Term : 'canonical Wnt signaling pathway' added !
40794view22:16, 1 March 2011MaintBotRemoved redundant pathway information and comments
21872view11:32, 14 November 2008MaintBot[[Pathway:Danio rerio:Wnt Signaling canonical]] moved to [[Pathway:WP566]]: Moved to stable identifier
16299view20:45, 17 June 2008Khanspers[[Pathway:Danio rerio:Dr Wnt-signaling canonical]] moved to [[Pathway:Danio rerio:Wnt Signaling canonical]]: Removed species code prefix from pathway name
14269view07:09, 22 May 2008SFGKrensModified categories
14038view08:02, 21 May 2008SFGKrensNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
APCGeneProduct386762 (Entrez Gene)
CBP / p300GeneProductDr.75365 (UniGene)
CKI-alphaGeneProduct
E-cadherinGeneProductDr.78411 (UniGene)
E12 / tcf3GeneProduct30310 (Entrez Gene)
GBPGeneProductDr.81277 (UniGene)
LRP5GeneProduct554087 (Entrez Gene)
NLKGeneProduct405892 (Entrez Gene)
PKCGeneProduct334077 (Entrez Gene)
RA receptor gGeneProduct30606 (Entrez Gene)
RhoAaGeneProductDr.32765 (UniGene)
RhoAbGeneProduct336001 (Entrez Gene)
RhoAcGeneProduct406659 (Entrez Gene)
RhoAdGeneProduct436718 (Entrez Gene)
RhoAeGeneProductDr.75611 (UniGene)
Tak1GeneProduct553788 (Entrez Gene)
VEGFaGeneProductDr.597 (UniGene)
axin1GeneProduct57931 (Entrez Gene) masterblind
axin2 / conductinGeneProduct58080 (Entrez Gene)
axin2GeneProduct58080 (Entrez Gene)
beta-catenin1GeneProduct30265 (Entrez Gene)
beta-catenin2GeneProduct
beta-catenin2GeneProduct324004 (Entrez Gene)
beta-catenin2GeneProductDr.29035 (UniGene)
bglapGeneProduct494531 (Entrez Gene)
birc5aGeneProduct373110 (Entrez Gene)
birc5bGeneProduct246726 (Entrez Gene)
bmp2bGeneProduct30632 (Entrez Gene)
bmp4GeneProduct30612 (Entrez Gene)
bozGeneProduct30170 (Entrez Gene)
c-junGeneProductDr.1064 (UniGene)
c-mycGeneProductDr.1 (UniGene)
camk1gGeneProduct335654 (Entrez Gene)
camk2dGeneProductDr.12561 (UniGene)
catenin-beta 1GeneProduct30265 (Entrez Gene) ’catenin (cadherin-associated protein), beta 1 ’
ccnd1GeneProduct30222 (Entrez Gene)
cdc42GeneProduct336839 (Entrez Gene)
cdc42l2GeneProduct556226 (Entrez Gene)
cdc42lGeneProductDr.1474 (UniGene)
cdh1 / E-cadherinGeneProductDr.78411 (UniGene)
cdx1aGeneProduct405762 (Entrez Gene)
cdx4GeneProduct30330 (Entrez Gene)
chdGeneProductENSDARG00000006110 (Ensembl)
ck2a1GeneProduct30502 (Entrez Gene)
ck2a2GeneProduct30488 (Entrez Gene)
ck2bGeneProduct30428 (Entrez Gene)
connexin 43GeneProduct30236 (Entrez Gene)
cspg2a /versicanGeneProduct30299 (Entrez Gene)
ctbp1GeneProduct65229 (Entrez Gene)
ctbp2GeneProduct65230 (Entrez Gene)
ctbp2lGeneProduct548605 (Entrez Gene)
ctnnb1GeneProduct30265 (Entrez Gene)
ctnnb2GeneProductDr.29035 (UniGene)
cyclinD1GeneProduct30222 (Entrez Gene)
dab2GeneProduct404040 (Entrez Gene)
dact1 / dapper1GeneProduct405799 (Entrez Gene)
dact2 / dapper2GeneProduct337795 (Entrez Gene)
dact2 / drapperGeneProduct337795 (Entrez Gene) ’dapper homolog 2, antagonist of beta-catenin’
dkk1GeneProduct30197 (Entrez Gene)
dlaGeneProduct30131 (Entrez Gene)
dldGeneProductDr.75102 (UniGene)
drl / rykGeneProduct30167 (Entrez Gene)
dvl2GeneProduct323630 (Entrez Gene) deshevelled2
dvl3GeneProduct80972 (Entrez Gene) deshevelled3
edaGeneProductZDB-GENE-050107-6 (ZFIN)
egfrGeneProductDr.82227 (UniGene)
endothelin 1GeneProductDr.4076 (UniGene)
engrailed 1aGeneProduct30244 (Entrez Gene)
engrailed 1bGeneProduct30233 (Entrez Gene)
engrailed 2aGeneProduct30243 (Entrez Gene)
engrailed 2bGeneProduct30238 (Entrez Gene)
ephrin B1GeneProduct114377 (Entrez Gene)
ermGeneProduct30452 (Entrez Gene)
eve1GeneProduct30335 (Entrez Gene)
fgf18GeneProduct359829 (Entrez Gene)
fgf18lGeneProduct497639 (Entrez Gene)
fgf20aGeneProduct559630 (Entrez Gene)
fgf20bGeneProduct564770 (Entrez Gene)
fgf3GeneProduct30549 (Entrez Gene)
fgf4GeneProduct60311 (Entrez Gene)
fgf8GeneProduct30538 (Entrez Gene)
fibronectin 1GeneProduct58034 (Entrez Gene)
fibronectin 1bGeneProduct334613 (Entrez Gene)
follistatinGeneProduct30235 (Entrez Gene)
foxN1GeneProduct266748 (Entrez Gene)
frzbGeneProduct30119 (Entrez Gene)
fz12GeneProduct30275 (Entrez Gene)
fzd10GeneProduct30366 (Entrez Gene)
fzd1GeneProduct30365 (Entrez Gene)
fzd2GeneProduct30370 (Entrez Gene)
fzd3GeneProduct30371 (Entrez Gene)
fzd4GeneProduct30363 (Entrez Gene)
fzd7aGeneProductENSDARG00000060004 (Ensembl)
fzd7bGeneProduct30412 (Entrez Gene)
fzd8aGeneProduct58073 (Entrez Gene)
fzd8cGeneProduct30364 (Entrez Gene)
fzd9GeneProduct58023 (Entrez Gene)
gata2GeneProduct30480 (Entrez Gene)
groucho1GeneProduct100007463 (Entrez Gene)
groucho2GeneProduct30206 (Entrez Gene)
groucho3GeneProduct83411 (Entrez Gene)
gscGeneProductENSDARG00000059073 (Ensembl)
gsk3bGeneProduct30654 (Entrez Gene)
hoxb1bGeneProduct30374 (Entrez Gene)
icatGeneProduct58117 (Entrez Gene) beta-catenin-interacting protein
id2aGeneProduct266599 (Entrez Gene)
id2bGeneProduct321364 (Entrez Gene)
ikbkg / nemoGeneProductDr.69759 (UniGene)
irx3aGeneProduct30520 (Entrez Gene)
irx3bGeneProductDr.30395 (UniGene)
jagged 1aGeneProduct140421 (Entrez Gene)
jagged 1bGeneProduct140423 (Entrez Gene)
ldlrGeneProduct387529 (Entrez Gene)
lef1GeneProductDr.64686 (UniGene)
lefGeneProductENSDARG00000031894 (Ensembl)
lim1GeneProduct30463 (Entrez Gene)
metGeneProduct100150664 (Entrez Gene)
mitfaGeneProduct30080 (Entrez Gene)
mkp3GeneProduct353314 (Entrez Gene)
mycaGeneProductDr.1 (UniGene)
neurogenin 1GeneProduct30239 (Entrez Gene)
nkd1GeneProduct751108 (Entrez Gene)
nos2GeneProduct404036 (Entrez Gene)
ntlGeneProduct30399 (Entrez Gene)
oepGeneProductENSDARG00000035095 (Ensembl)
otx1GeneProduct30500 (Entrez Gene)
otx2GeneProduct30501 (Entrez Gene)
par1GeneProductDr.81253 (UniGene)
peaGeneProductDr.75840 (UniGene)
periostinGeneProductDr.30157 (UniGene)
pitx2aGeneProduct30164 (Entrez Gene)
pitx2bGeneProductZDB-GENE-030912-12 (ZFIN)
pontin52 / ruvbl1GeneProduct317679 (Entrez Gene)
ppp2r5e1GeneProduct373878 (Entrez Gene)
ppp2r5e2GeneProductDr.79532 (UniGene)
prkcb1GeneProduct393953 (Entrez Gene)
prkcb1lGeneProduct394004 (Entrez Gene)
prkciGeneProduct117507 (Entrez Gene)
prkcl2GeneProduct323182 (Entrez Gene)
ptgs2GeneProduct246227 (Entrez Gene)
rac1GeneProduct327204 (Entrez Gene)
rac2GeneProduct415151 (Entrez Gene)
rac3GeneProduct437027 (Entrez Gene)
rfzd8bGeneProduct58072 (Entrez Gene)
rhoua /wrch1GeneProduct492802 (Entrez Gene)
runx2aGeneProduct405784 (Entrez Gene)
runx2bGeneProductDr.30423 (UniGene)
ruvbl2 / reptinGeneProduct317678 (Entrez Gene)
sall4GeneProductZDB-GENE-060328-2 (Other)
sfrp1aGeneProductDr.105557 (UniGene)
sfrp2GeneProduct566878 (Entrez Gene)
sfrp2GeneProductDr.76476 (UniGene)
sfrp2lGeneProductZDB-GENE-061122-2 (ZFIN)
sfrp5GeneProductDr.86566 (UniGene)
sfzd1GeneProduct402843 (Entrez Gene) secreted frizzled-related protein
sfzd5GeneProduct117510 (Entrez Gene) secreted frizzled-related protein
smarca4GeneProduct353295 (Entrez Gene)
smoGeneProduct30225 (Entrez Gene)
sox17GeneProduct30544 (Entrez Gene)
sox2GeneProduct378723 (Entrez Gene)
sox9aGeneProduct60641 (Entrez Gene)
sox9bGeneProduct60642 (Entrez Gene)
sp5GeneProductDr.78633 (UniGene)
sp5lGeneProduct324261 (Entrez Gene)
spry2GeneProduct335098 (Entrez Gene)
spry4GeneProduct114437 (Entrez Gene)
sqtGeneProduct30153 (Entrez Gene)
stripe / egr2bGeneProduct30190 (Entrez Gene)
tcf-1 / elk4GeneProduct447862 (Entrez Gene)
tcf1GeneProduct266961 (Entrez Gene)
tcf3 / tcf7l1aGeneProductENSDARG00000038159 (Ensembl)
tcf3b / tcf7l1bGeneProduct30556 (Entrez Gene)
tcf4GeneProduct30510 (Entrez Gene)
tclGeneProduct386615 (Entrez Gene) secreted frizzled-related protein
twistGeneProduct30175 (Entrez Gene)
ubxd1GeneProduct327469 (Entrez Gene)
vedGeneProduct368201 (Entrez Gene)
vegfcGeneProductDr.88903 (UniGene)
ventGeneProduct64810 (Entrez Gene)
voxGeneProduct64807 (Entrez Gene)
wif1GeneProduct30476 (Entrez Gene) wnt inhibitory factor 1
wisp2GeneProductZDB-GENE-060223-1 (ZFIN)
wnt10aGeneProductENSDARG00000017155 (Ensembl)
wnt10bGeneProductENSDARG00000040925 (Ensembl)
wnt11GeneProduct30139 (Entrez Gene) silberblick
wnt11rGeneProductENSDARG00000014796 (Ensembl)
wnt16GeneProduct791563 (Entrez Gene)
wnt1GeneProductENSDARG00000055554 (Ensembl)
wnt2GeneProduct30127 (Entrez Gene)
wnt2bGeneProductENSDARG00000005050 (Ensembl)
wnt3lGeneProductENSDARG00000058822 (Ensembl)
wnt4aGeneProductENSDARG00000071208 (Ensembl)
wnt4bGeneProductENSDARG00000040159 (Ensembl)
wnt5bGeneProduct30105 (Entrez Gene)
wnt7GeneProduct60633 (Entrez Gene)
wnt7aGeneProduct565714 (Entrez Gene)
wnt8aGeneProduct30122 (Entrez Gene)
wnt8bGeneProduct30144 (Entrez Gene)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP566"
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