RNA pol II transcription - Initiation and elongation (Homo sapiens)

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PROMOTER5'DSIFNucleusHEXIM1SUPT4H1CycT1SUPT5HRNA Pol IICDK9HistonesMCL1NELFANELFBAc3'CytoplasmCDK9CycT1NELFCDNELFEBRD4CycT1LEO1CTR9RTF1WDR61PAF1GRINL1APAF1CNELFpTEFbGdown1MEPCELARP7CDK7MAT1CycHXPDXPBGTF2H1GTF2H2GTF2H3GTF2H4GTF2H5TF-II HTF-II FGTF2F1GTF2F2TF-II EGTF2E1GTF2E2TF-II AGTF2A1GTF2A2GTF2BTF-II BTBPTAF1TAF2TAF3TAF5TAF7TAF9TAF4TAF6TAF8TAF4BTAF9BTAF10TAF11TAF12TAF13TF-II DENHANCERMED1MED4MED6MED7MED8MED9MED10MED11MED12MED16MED13MED17MED14MED18MED15MED19MED20MED24MED21MED25MED22MED26MED23MED27MED28MED29MED30MED31CDK8CDK19Cyc CMediator Complex7SK-pTEF complexCDK9AFF4ENLEAF1ELL2SECMYC


Description

This Wikipathway represents the mediators and complexes associated to RNA polymerase II during initiation and elongation of transcription in human cells as reported in (1) and (2).

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
121484view06:43, 18 February 2022DiazfloreseModified description
121483view06:42, 18 February 2022DiazfloreseModified description
121482view06:40, 18 February 2022DiazfloreseModified description
121481view06:40, 18 February 2022DiazfloreseModified description
121480view06:37, 18 February 2022DiazfloreseModified description
121479view06:37, 18 February 2022DiazfloreseModified description
116607view09:36, 9 May 2021EweitzOntology Term : 'RNA polymerase II transcription initiation pathway' added !
116606view09:35, 9 May 2021EweitzOntology Term : 'RNA polymerase II transcription elongation pathway' added !
116605view09:34, 9 May 2021EweitzModified title
110902view19:16, 18 June 2020DiazfloreseNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AFF4GeneProductENSG00000072364 (Ensembl)
BRD4GeneProductENSG00000141867 (Ensembl)
CDK19GeneProductENSG00000155111 (Ensembl)
CDK7GeneProductENSG00000134058 (Ensembl)
CDK8GeneProductENSG00000132964 (Ensembl)
CDK9GeneProductENSG00000136807 (Ensembl)
CTR9GeneProductENSG00000198730 (Ensembl)
Cyc CGeneProductENSG00000112237 (Ensembl)
CycHGeneProductENSG00000134480 (Ensembl)
CycT1GeneProductENSG00000129315 (Ensembl)
EAF1GeneProductENSG00000144597 (Ensembl)
ELL2GeneProductENSG00000118985 (Ensembl)
ENLGeneProductENSG00000130382 (Ensembl)
GRINL1AGeneProductENSG00000137878 (Ensembl)
GTF2A1GeneProductENSG00000165417 (Ensembl)
GTF2A2GeneProductENSG00000140307 (Ensembl)
GTF2BGeneProductENSG00000137947 (Ensembl)
GTF2E1GeneProductENSG00000153767 (Ensembl)
GTF2E2GeneProductENSG00000197265 (Ensembl)
GTF2F1GeneProductENSG00000125651 (Ensembl)
GTF2F2GeneProductENSG00000188342 (Ensembl)
GTF2H1GeneProductENSG00000110768 (Ensembl)
GTF2H2GeneProductENSG00000145736 (Ensembl)
GTF2H3GeneProductENSG00000111358 (Ensembl)
GTF2H4GeneProductENSG00000213780 (Ensembl)
GTF2H5GeneProductENSG00000272047 (Ensembl)
HEXIM1GeneProductENSG00000186834 (Ensembl)
HistonesGeneProduct
LARP7GeneProductENSG00000174720 (Ensembl)
LEO1GeneProductENSG00000166477 (Ensembl)
MAT1GeneProductENSG00000020426 (Ensembl)
MCL1GeneProductENSG00000143384 (Ensembl)
MED10GeneProductENSG00000133398 (Ensembl)
MED11GeneProductENSG00000161920 (Ensembl)
MED12GeneProductENSG00000184634 (Ensembl)
MED13GeneProductENSG00000108510 (Ensembl)
MED14GeneProductENSG00000180182 (Ensembl)
MED15GeneProductENSG00000099917 (Ensembl)
MED16GeneProductENSG00000175221 (Ensembl)
MED17GeneProductENSG00000042429 (Ensembl)
MED18GeneProductENSG00000130772 (Ensembl)
MED19GeneProductENSG00000156603 (Ensembl)
MED1GeneProductENSG00000125686 (Ensembl)
MED20GeneProductENSG00000124641 (Ensembl)
MED21GeneProductENSG00000152944 (Ensembl)
MED22GeneProductENSG00000148297 (Ensembl)
MED23GeneProductENSG00000112282 (Ensembl)
MED24GeneProductENSG00000008838 (Ensembl)
MED25GeneProductENSG00000104973 (Ensembl)
MED26GeneProductENSG00000105085 (Ensembl)
MED27GeneProductENSG00000160563 (Ensembl)
MED28GeneProductENSG00000118579 (Ensembl)
MED29GeneProductENSG00000063322 (Ensembl)
MED30GeneProductENSG00000164758 (Ensembl)
MED31GeneProductENSG00000108590 (Ensembl)
MED4GeneProductENSG00000136146 (Ensembl)
MED6GeneProductENSG00000133997 (Ensembl)
MED7GeneProductENSG00000155868 (Ensembl)
MED8GeneProductENSG00000159479 (Ensembl)
MED9GeneProductENSG00000141026 (Ensembl)
MEPCEGeneProductENSG00000146834 (Ensembl)
MYCGeneProductENSG00000136997 (Ensembl)
NELFAGeneProductENSG00000185049 (Ensembl)
NELFBGeneProductENSG00000188986 (Ensembl)
NELFCDGeneProductENSG00000101158 (Ensembl)
NELFEGeneProduct7936 (Entrez Gene)
PAF1GeneProductENSG00000006712 (Ensembl)
RNA Pol IIGeneProduct
RTF1GeneProductENSG00000137815 (Ensembl)
SUPT4H1GeneProductENSG00000213246 (Ensembl)
SUPT5HGeneProductENSG00000196235 (Ensembl)
TAF10GeneProductENSG00000166337 (Ensembl)
TAF11GeneProductENSG00000064995 (Ensembl)
TAF12GeneProductENSG00000120656 (Ensembl)
TAF13GeneProductENSG00000197780 (Ensembl)
TAF1GeneProductENSG00000147133 (Ensembl)
TAF2GeneProductENSG00000064313 (Ensembl)
TAF3GeneProductENSG00000165632 (Ensembl)
TAF4BGeneProductENSG00000141384 (Ensembl)
TAF4GeneProductENSG00000130699 (Ensembl)
TAF5GeneProductENSG00000148835 (Ensembl)
TAF6GeneProductENSG00000106290 (Ensembl)
TAF7GeneProductENSG00000178913 (Ensembl)
TAF8GeneProductENSG00000137413 (Ensembl)
TAF9BGeneProductENSG00000187325 (Ensembl)
TAF9GeneProductENSG00000273841 (Ensembl)
TBPGeneProductENSG00000112592 (Ensembl)
WDR61GeneProductENSG00000140395 (Ensembl)
XPBGeneProductENSG00000163161 (Ensembl)
XPDGeneProductENSG00000104884 (Ensembl)

Annotated Interactions

No annotated interactions

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