Alanine and aspartate metabolism (Bos taurus)

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1, 2Citrate cycle (TCA cycle)Fatty acid metabolismProteinL-Alanyl-tRNADARSMalate2.6.1.141.4.3.2L-AsparagineAcetyl-CoAL-aspartateGAD2D-Ala metabolismGOT2L-Aspartic acidHistidine metabolism2.1.3.2beta-Alanine metabolismReductive carboxylate cycle (CO2 fixation)FumarateCyanoamino acid metabolism1.2.1.186.3.4.4Nicotinate and nicotinamide metabolism2.3.1.72-Oxoglutarate1.4.3.15.1.1.13L-Asparagine acid1.4.3.16Pyrimidine metabolismL-AlanineUrea cycel and metabolism of amino groupsL-Argininosuccinate6.3.2.113.5.1.14.3.2.2ASPA6.3.5.4Reductive carboxylatecycle (CO2 fixation)tRNA (Asn)N-Carbamoyl-L-aspartate3.4.13.3Glycine, serine and threonine metabolismSelenoamino acid metabolismAGXT3.5.1.36.3.1.1tRNA (Asn)b-Alanine4.1.1.11Glycolysis & gluconeogenesis3.5.1.7OxaloacetateLysine biosynthesisD-AlanineD-aspartatePC2.6.1.18GOT1Adenylosuccinate6.1.1.226.3.5.6Pantothenate and CoA biosynthesis6.1.1.71.4.3.15GAD14.3.1.1CarnosineABATASS1tRNA(Asp)SuccinateDARSNicotinate and nicotinamide metabolismArginine and Proline metabolismMalonate semialdehydeASLGPTN-Acetyl-L-aspartate2.6.1.125.1.1.14.1.1.122-Oxosuccinamate3.5.1.38O-AcetylcarnitinePyruvateCitric acidL-Asparagine acid


Description

Originally based on KEGG: http://www.genome.ad.jp/dbget-bin/show pathway?rno00252 Edited by Sebastien Burel.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP106(74147) with a 29.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Wu G; ''Intestinal mucosal amino acid catabolism.''; J Nutr, 1998 PubMed Europe PMC Scholia
  2. Curien G, Bastien O, Robert-Genthon M, Cornish-Bowden A, Cárdenas ML, Dumas R; ''Understanding the regulation of aspartate metabolism using a model based on measured kinetic parameters.''; Mol Syst Biol, 2009 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123267view09:07, 9 July 2022EgonwMade three pathways clickable
107073view14:16, 17 September 2019MaintBotChEBI identifier normalization
105967view11:49, 16 August 2019MaintBotHMDB identifier normalization
102419view10:03, 23 December 2018EgonwReplaced a deleted CAS number with the active one.
92990view18:16, 21 July 2017Khanspersfixed unconnected
92989view18:11, 21 July 2017KhanspersModified description
92988view18:10, 21 July 2017Khanspersremoved GenMAPP notes
92895view19:09, 14 July 2017EgonwReplace a CAS number for a totally different compound with the ChEBI ID for L-alanine.
80904view15:30, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1.2.1.18GeneProduct
1.4.3.1GeneProduct
1.4.3.15GeneProduct
1.4.3.16GeneProduct
1.4.3.2GeneProduct
2-OxoglutarateMetaboliteC00026 (KEGG Compound)
2-OxosuccinamateMetabolite
2.1.3.2GeneProduct
2.3.1.7GeneProduct
2.6.1.12GeneProduct
2.6.1.14GeneProduct
2.6.1.18GeneProduct
3.4.13.3GeneProduct
3.5.1.1GeneProduct
3.5.1.3GeneProduct
3.5.1.38GeneProduct
3.5.1.7GeneProduct
4.1.1.11GeneProduct
4.1.1.12GeneProduct
4.3.1.1GeneProduct
4.3.2.2GeneProduct
5.1.1.1GeneProduct
5.1.1.13GeneProduct
6.1.1.22GeneProduct
6.1.1.7GeneProduct
6.3.1.1GeneProduct
6.3.2.11GeneProduct
6.3.4.4GeneProduct
6.3.5.4GeneProduct
6.3.5.6GeneProduct
ABATGeneProductENSBTAG00000004038 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:18
AGXTGeneProductENSBTAG00000005797 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:189
ASLGeneProductENSBTAG00000015314 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:435
ASPAGeneProductENSBTAG00000003629 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:443
ASS1GeneProductENSBTAG00000020747 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:445
Acetyl-CoAMetabolite72-89-9 (CAS) Acetyl-CoA
AdenylosuccinateMetabolite
Arginine and Proline metabolismPathway
CarnosineMetabolite305-84-0 (CAS) Carnosine
Citric acidMetaboliteHMDB0000094 (HMDB)
Cyanoamino acid metabolismPathway
D-Ala metabolismPathway
D-AlanineMetabolite338-69-2 (CAS) D-Alanine
D-aspartateMetaboliteC00402 (KEGG Compound)
DARSGeneProductENSBTAG00000009949 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1615
Fatty acid metabolismPathwayWP143 (WikiPathways)
FumarateMetaboliteC00122 (KEGG Compound)
GAD1GeneProductENSBTAG00000007258 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2571
GAD2GeneProductENSBTAG00000008056 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2572
GOT1GeneProductENSBTAG00000011960 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2805
GOT2GeneProductENSBTAG00000007172 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2806
GPTGeneProductENSBTAG00000007835 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2875
Glycine, serine and threonine metabolismPathway
Glycolysis & gluconeogenesisPathwayWP534 (WikiPathways)
Histidine metabolismPathway
L-AlanineMetaboliteCHEBI:16977 (ChEBI)
L-ArgininosuccinateMetaboliteCHEBI:15682 (ChEBI)
L-Asparagine acidMetabolite70-47-3 (CAS)
L-AsparagineMetabolite70-47-3 (CAS) L-Asparagine
L-Aspartic acidMetaboliteC00049 (KEGG Compound)
L-aspartateMetaboliteC00049 (KEGG Compound)
Lysine biosynthesisPathway
MalateMetabolite6915-15-7 (CAS) (S)-Malate
Malonate semialdehydeMetaboliteCHEBI:33190 (ChEBI)
N-Acetyl-L-aspartateMetabolite
N-Carbamoyl-L-aspartateMetaboliteCHEBI:15859 (ChEBI)
Nicotinate and nicotinamide metabolismPathway
O-AcetylcarnitineMetabolite3040-38-8 (CAS)
OxaloacetateMetaboliteC00036 (KEGG Compound)
PCGeneProductENSBTAG00000019700 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5091
Pantothenate and CoA biosynthesisPathway
Pyrimidine metabolismPathway
PyruvateMetaboliteCHEBI:32816 (ChEBI)
Reductive carboxylate cycle (CO2 fixation)Pathway
Reductive carboxylate cycle (CO2 fixation)Pathway
Selenoamino acid metabolismPathway
SuccinateMetaboliteC00042 (KEGG Compound)
Urea cycel and metabolism of amino groupsPathwayWP497 (WikiPathways)
b-AlanineMetabolite6912-68-1 (CAS) beta-alanine
beta-Alanine metabolismPathway
tRNA (Asn)GeneProduct
tRNA(Asp)GeneProduct

Annotated Interactions

No annotated interactions
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