Globo series sphingolipid metabolism (Mus musculus)
From WikiPathways
Description
Globoseries sphingolipid biosynthesis taken from Sphingomap.
Solid conversion arrows are documented according to Sphingomap. Thicker lines are those reactions not found in Rhea. Dotted conversions are hypothetical, either not occurring or undocumented (Sphingomap details all possible permutations of a pathway to the final glycolipid) p Numbers are the sphingomap IDs, to be converted.
Metabolites with a dotted box are hypothetical. These may or may not exist on the pathway to the final product as several different routes could occur.Quality Tags
Ontology Terms
Bibliography
- Merril AH Jr; ''SphinGOMAP--a web-based biosynthetic pathway map of sphingolipids and glycosphingolipids.''; Glycobiology, 2005 PubMed Europe PMC Scholia
- ''Handbook of Glycosyltransferases and Related Genes''; https://doi.org/10.1007/978-4-431-67877-9, 2002 DOI Scholia
History
View all... |
External references
DataNodes
View all... |
Name | Type | Database reference | Comment |
---|---|---|---|
110 | Metabolite | LMSP0502AL00 (LIPID MAPS) | |
111 | Metabolite | LMSP0502AM00 (LIPID MAPS) | |
113 | Metabolite | LMSP0601AC00 (LIPID MAPS) | |
114 | Metabolite | LMSP0601AD00 (LIPID MAPS) | |
115 | Metabolite | LMSP0601AE00 (LIPID MAPS) | |
131 | Metabolite | LMSP0502AO00 (LIPID MAPS) | |
132 | Metabolite | LMSP0502AP00 (LIPID MAPS) | |
135 | Metabolite | LMSP0601AF00 (LIPID MAPS) | |
136 | Metabolite | LMSP0601AG00 (LIPID MAPS) | |
137 | Metabolite | LMSP0601AH00 (LIPID MAPS) | |
138 | Metabolite | LMSP0502AS00 (LIPID MAPS) | |
139 Branched Forssman | Metabolite | LMSP0502AT00 (LIPID MAPS) | |
140 | Metabolite | LMSP0502AU00 (LIPID MAPS) | |
141 | Metabolite | LMSP0502BA00 (LIPID MAPS) | |
142 | Metabolite | LMSP0502AV00 (LIPID MAPS) | |
403 Globopentaosylceramide sulfate | Metabolite | LMSP0602AB00 (LIPID MAPS) | |
405 Sulfoglobotetraosylceramide | Metabolite | LMSP0602AC00 (LIPID MAPS) | |
406 SSEA-4 isomer | Metabolite | LMSP0601AI00 (LIPID MAPS) | |
414 | Metabolite | LMSP0502BB00 (LIPID MAPS) | |
436 | Metabolite | LMSP0502BC00 (LIPID MAPS) | |
438 | Metabolite | LMSP0502BD00 (LIPID MAPS) | |
441 | Metabolite | LMSP0502BE00 (LIPID MAPS) | |
442 | Metabolite | LMSP0502BF00 (LIPID MAPS) | |
443 | Metabolite | LMSP0502BG00 (LIPID MAPS) | |
444 | Metabolite | LMSP0502BH00 (LIPID MAPS) | |
445 | Metabolite | LMSP0502BI00 (LIPID MAPS) | |
446 | Metabolite | LMSP0502BJ00 (LIPID MAPS) | |
447 | Metabolite | LMSP0502BK00 (LIPID MAPS) | |
448 | Metabolite | LMSP0502BL00 (LIPID MAPS) | |
449 | Metabolite | LMSP0502BM00 (LIPID MAPS) | |
450 | Metabolite | LMSP0502BN00 (LIPID MAPS) | |
B3galnt1 | GeneProduct | Q920V1 (Uniprot-TrEMBL) | |
B3galt5 | GeneProduct | Q9JI67 (Uniprot-TrEMBL) | |
B4galt family | GeneProduct | EC:2.4.1.22 | |
B6glcnacT family | Protein | EC: | |
Forssman antigen | Metabolite | LMSP0502AC00 (LIPID MAPS) | |
Fut2 | GeneProduct | Q9JL27 (Uniprot-TrEMBL) | |
GB3 | Metabolite | LMSP0502AA00 (LIPID MAPS) | |
Galbeta1-3(Galbeta1-4GlcNAcbeta1-6)GalNAcbeta1-3Galalpha1-4Galbeta1-4Glcbeta-Cer | Metabolite | LMSP0502AG00 (LIPID MAPS) | sphingomap id 23 |
Galbeta1-3(GlcNAcbeta1-6)GalNAcbeta1-3Galalpha1-4Galbeta1-4Glcbeta-Cer | Metabolite | LMSP0502AF00 (LIPID MAPS) | |
Gbgt1 | GeneProduct | Q8VI38 (Uniprot-TrEMBL) | |
Globoside I GB4Cer | Metabolite | LMSP0502AB00 (LIPID MAPS) | S_id 18 |
Para-Forssman x3b | Metabolite | LMSP0502AD00 (LIPID MAPS) | S_id 20 |
SSEA-3 antigen | Metabolite | LMSP0502AE00 (LIPID MAPS) | sphingomap id 21 |
SSEA-4 antigen | Metabolite | LMSP0601AB00 (LIPID MAPS) | |
St3gal family | Protein | ||
Type IV A antigen | Metabolite | LMSP0502AJ00 (LIPID MAPS) | |
Type IV B antigen | Metabolite | type IV B antigen (LIPID MAPS) | |
a3GalNAcT family | Protein | ||
a3GalT family | Protein | ||
a3fucT family | GeneProduct | ||
globo-Lex-9 | Metabolite | LMSP0502AH00 (LIPID MAPS) | Sphingomap_id 25 |
type IV H | Metabolite | LMSP0502AI00 (LIPID MAPS) | Sphingomap id 26 |
112 | Metabolite | ||
133 | Metabolite | ||
134 | Metabolite | ||
143 | Metabolite | ||
144 | Metabolite | ||
145 | Metabolite | ||
146 | Metabolite | ||
437 | Metabolite | ||
439 | Metabolite | ||
440 | Metabolite |
Annotated Interactions
View all... |
Source | Target | Type | Database reference | Comment |
---|---|---|---|---|
B3galnt1 | mim-catalysis | 22253 (Rhea) | EC:2.4.1.79 | |
GB3 | Globoside I GB4Cer | mim-conversion | 22253 (Rhea) | |
Globoside I GB4Cer | Forssman antigen | mim-conversion | 22165 (Rhea) | EC:2.4.1.88 |
Globoside I GB4Cer | GB3 | mim-conversion | 48037 (Rhea) | |
Globoside I GB4Cer | SSEA-3 antigen | mim-conversion | 41997 (Rhea) | |
SSEA-3 antigen | type IV H | mim-conversion | 42045 (Rhea) | EC:2.4.1.69 |