De novo biosynthesis of pyrimidine ribonucleotides (Saccharomyces cerevisiae)
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carbamoyl-L-aspartate
dihydroorotate
H+
orotidine-5â-phosphate
UTP
CTP
UMP
H2O
acceptor
UDP
HCO3-
L-aspartate
CO2
H2O
H2O
carbomoyl-phosphate
reduced acceptor
orotate
URA10
CDP
ADP
ATP
URA4
YNK1
2 ADP
phosphate
L-glutamate
L-glutamate
URA1
URA5
L-glutamine
pyrophosphate
URA6
ATP
URA3
ADP
PRPP
ADP
L-glutamine
URA7
ATP
ATP
URA2
ADP
phosphate
URA8
phosphate
URA2
2 ATP
Description
No description
Comments
GenMAPP remarks
Based on
http://pathway.yeastgenome.org/biocyc/
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Bibliography
Wagner R, de Montigny J, de Wergifosse P, Souciet JL, Potier S; ''The ORF YBL042 of Saccharomyces cerevisiae encodes a uridine permease.''; FEMS Microbiol Lett, 1998
PubMed
Europe PMC
Scholia
''de novo biosynthesis of pyrimidine ribonucleotides''; YeastPathways,
History
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Time
User
Comment
135756
view
12:01, 9 November 2024
Egonw
Normalized a EC identifier
135633
view
04:22, 8 October 2024
Khanspers
board size
135632
view
04:21, 8 October 2024
Khanspers
updated reference
135631
view
04:19, 8 October 2024
Khanspers
overhaul
135621
view
21:49, 7 October 2024
Khanspers
Ontology Term : 'classic metabolic pathway' added !
135620
view
21:44, 7 October 2024
Khanspers
removed GenMAPP comments
135619
view
21:42, 7 October 2024
Khanspers
Modified description
117290
view
11:02, 20 May 2021
Eweitz
Modified title
107032
view
13:48, 17 September 2019
MaintBot
HMDB identifier normalization
102792
view
13:45, 24 January 2019
Egonw
Better PubChem ID.
87230
view
14:47, 19 July 2016
Susan
Ontology Term : 'de novo pyrimidine biosynthetic pathway' added !
87229
view
14:47, 19 July 2016
Susan
Ontology Term : 'PW:0000861' removed !
87226
view
14:44, 19 July 2016
Susan
Ontology Term : 'pyrimidine biosynthetic pathway' added !
71184
view
15:09, 11 October 2013
Egonw
Fixed a metabolite label and added its identifier.
71183
view
15:01, 11 October 2013
Egonw
Added missing metabolite identifiers.
71182
view
14:48, 11 October 2013
Egonw
Periodical save, work in progress
70996
view
15:30, 22 September 2013
Egonw
Added metabolite identifiers.
70248
view
21:36, 15 July 2013
MaintBot
updated to 2013 schema
70053
view
06:01, 12 July 2013
Egonw
Marked a few DataNodes with CAS registry numbers as metabolites.
69729
view
08:03, 11 July 2013
Egonw
Give water HMDB ids.
54773
view
07:18, 9 December 2012
Egonw
Replaced multiple general nodes by Metabolite DataNode's.
54772
view
07:14, 9 December 2012
Egonw
Connecting dots
41915
view
04:54, 2 March 2011
MaintBot
Removed redundant pathway information and comments
36648
view
22:38, 9 April 2010
MaintBot
Description and bibliography added from SGD
20875
view
11:30, 14 November 2008
MaintBot
[[Pathway:Saccharomyces cerevisiae:De Novo Biosynthesis of Pyrimidine Ribonucleotides]] moved to [[Pathway:WP92]]: Moved to stable identifier
12686
view
07:58, 17 May 2008
MaintBot
automated metabolite conversion
8690
view
14:06, 7 January 2008
MaintBot
Added to category $category
8688
view
14:06, 7 January 2008
M.Braymer
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
2 ADP
58-64-0 (CAS)
2 ATP
1927-31-7 (CAS)
ADP
58-64-0 (CAS)
ATP
1927-31-7 (CAS)
CDP
63-38-7 (CAS)
L-glutamate
56-86-0 (CAS)
L-glutamine
56-85-9 (CAS)
PRPP
97-55-2 (CAS)
URA10
GeneProduct
S000004884 (SGD)
URA1
GeneProduct
S000001699 (SGD)
URA2
GeneProduct
S000003666 (SGD)
URA3
GeneProduct
S000000747 (SGD)
URA4
GeneProduct
S000004412 (SGD)
URA5
GeneProduct
S000004574 (SGD)
URA6
GeneProduct
S000001507 (SGD)
URA7
GeneProduct
S000000135 (SGD)
URA8
GeneProduct
S000003864 (SGD)
YNK1
GeneProduct
S000001550 (SGD)
phosphate
14265-44-2 (CAS)
pyrophosphate
2466-09-3 (CAS)
Annotated Interactions
No annotated interactions
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