Cancer pathways (Homo sapiens)

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Revision as of 22:58, 2 January 2024 by Khanspers (Talk | contribs)
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MitochondriaMicrotubuleWntLigandsDNA damageTelomeric DNA repeatsPU.1 target genesOxidative or electrophilic stressRARatarget genesCytokine receptorCarcinogens?SustainedangiogenesisIL6FASLGTGFBR2TGFB1AXIN1Hydroxyl radicalKNG1RUNX1CASP3RASSF5RALASuperoxideCDKN1ASKP2KIF7GADD45GRARBJUPEstradiolCREBBPCCND1E2F1JAK1PGFCDK4KITVEGFDFRAT1RPS6KB1MTORRASGRP1SMODehydroepiandrosteroneRAC1ERBB2BCL2L1CTNNB1PIP3PGE2RALGDSPLCG1ROCK1PTENFGFR1CALML1MAPK8LEF1EstradiolCSF2RAITGB1CXCL12CCND1ESR1PTK2KLK3SMAD2PTGS2GRB2ProgesteroneCAMK2AMDM2MSH6STAT1MDM2VEGF signalingpathwayIGF1FLT3LGPPARDMETPLCB1PTGER1BIRC5ELOCMMP1BIRC2FOXO1PPAR signalingpathwayNQO1FGF1SPI1DAGHydrogen peroxideTGFAWnt signalingpathwayPAFocal adhesionCDKN1BEstrogen signalingpathwaySUFUSKP1BBC3PPARGPDGFATGFB1GNAI1HDAC1NFKB1JUNCXCL8DLL3RASSF1ELK1MLH1TP53AcroleinPLD1CDK4cAMP signalingpathwayCTNNB1CYCSCa2+FADDCDKN2BMSH3PRKACATERTCDH1CDKN2AfumarateCKS1BFLT4MSH2NOTCH1CASP3PDGFBRB1Adherens junctionTGFBR2RAD51Jak-STAT signaling pathwayCell cycleBAK1PI3K-Aktsignaling pathwayGSK3BPRKCAF2TGFBR1MYCTXNRD1MAPK1FASHGFPIK3CADCCTestosteroneHIF-1 signalingpathwayARLRP5TP53BADCTNNB1MAP2K1BCL2DDB2EDN1BMP2LPAR6TRAF1STAT5ANKX3-1EGFRPDGFRACUL2ZBTB17APC2CDKN1ACASP9NCOA3CSF3REGFCalcium signalingpathwayBIDCRKNFE2L2CHUKHEY1p53 signalingpathwayEPAS1Hydroperoxyl radicalFOSSMAD4KEAP1NOS2PMLDNAIP3RUNX1RHOASTAT3POLKRHOAALKIP3APAF1NFKBIACEBPABCL2L11PMAIP1cAMPMECOMEDNRAHHIPRASSF1CASP9RETHedgehog signaling pathwayHES1CCNA2CTNNA1GNASIGF1RMAPK signalingpathwaymTOR signalingpathwaySHHTGF-beta signalingpathwayRXRAJAG1APPL1VHLMYCPTCH1ApoptosisCDKN2ABADGNB5MAXMITFTERCCASP3CCND1RARAITGA6PIM2BCL2BAK1TFGARHGEF12CASP8CXCR4ARAFBAXFLT3GNA11WNT16BRCA2CSF1RHMOX1MYCRetinoic AcidDVL1CTBP1GSTP1BAXGNA13EGLN2ARNTMYCADCY1TGFARPS6KA5ABL1AGTRALBP1STAT2HRASSOS1SPI1CDK2ELOBPTCH1ETS1SLC2A1GLI1Nitric oxideRBX1HSP90AA1CholesterolFHDAPK1BCL2L1CCNE1Notch signaling pathwayCDKN1BKITLGPJAG2DLL4DLL1GLI2GLI3DihydrotestosteroneFlutamideAndrostenedioneCortisolCortisoneARHSP90AB1HSP90B1ARNOTCH2NOTCH3NOTCH4BMP4GLI1PTCH2HES5HEY2HEYLEGLN1EGLN3MalateHIF1AARNT2EP300VEGFAVEGFBVEGFCTGFB2TGFB34-HNETXNRD2TXNRD3CASP7Evaiding apoptosisMitochondriaTGFB2TGFB3SMAD3Genomic damageInsesitivity toanti-growth signalsResistance tochemotherapyImmortalityHDAC2CTBP2DNAGenomic instabilityGADD45BGADD45ACDK6CCND2CCND3E2F2E2F3ProliferationCCNE2RBX1CUL1CKS1BBlock ofdifferentiationE2F1E2F2E2F3CSF1RCSF1RC/EBPa target genesCEBPAAML1 target genesRARAZBTB16RUNX1RUNX1T1CCNA1CCND1TCF7TCF7L2TCF7L1SP1ESR2NCOA1ESR1ESR2EstradiolEstradiolRXRBRXRGRXRARXRBRXRGPPARGPAX8CCND1VEGFDVEGFAVEGFBVEGFCMMP2MMP3FOSMYCJUNMAPK3DAPK2DAPK3MAP2K2BRAFRAF1NRASKRASSOS2ERBB2PDGFRBFGFR2FGFR3FGFR4Cytokine IGF2PDGFBRALBPLD2RAC2RAC3MAPK9MAPK10RAC1RAC2RAC3CCDC42PLCG2EML4PRKCBPRKCGCCDC6NCOA4NTRK1TPM3TPRTissue invasion and metastasisCTNNA3CTNNA2AXIN2APCFRAT2DVL2DVL3MYCCCND1LEF1TCF7TCF7L2TCF7L1PGFVEGFDVEGFAVEGFBVEGFCLRP6PTGER2PTGER3PTGER4AGTR1LPAR1F2RLPAR2LPAR3LPAR4LPAR5F2RL3GNA12ARHGEF11ARHGEF1PLEKHG5ROCK2GNAI2GNAI3ADCY2ADCY3ADCY4ADCY5ADCY6ADCY7ADCY8ADCY9PRKACBPRKACGGNB1GNB2GNB3GNG3GNG4GNG5GNG7GNG10GNG11GNGT1BCL2L1PIM1BIRC3BIRC7XIAPTRAF2TRAF3TRAF4TRAF5TRAF6GNGT2GNG13GNG2GNG12GNG8GNB4ITGA2ITGA2BITGA3ITGAVEDNRBF2AGTBDKRB1BDKRB2GNAQPLCB2PLCB3PLCB4PRKCAPRKCBPRKCGCa2+DAGJAK2JAK3RASGRP2RASGRP3RASGRP4ALKEML4MST1STAT5BSTAT4STAT6BCRCBLCRKLPIK3CBPIK3CDPIK3R1PIK3R2PIK3R3AKT1AKT2AKT3IKBKBIKBKGNFKB2RELACASP9BCL2L1RPS6KB2CALML2CALML3CALML4CALML5CALML6CAMK2BCAMK2DCAMK2GWNT4WNT1WNT2WNT3WNT5AWNT6WNT7AWNT7BWNT8AWNT8BWNT10BWNT11WNT2BWNT9AWNT9BWNT10AWNT5BWNT3AFZD10FZD2FZD5FZD3FZD1FZD4FZD6FZD7FZD8FZD9LAMC3COL4A1COL4A2COL4A3COL4A4COL4A5COL4A6LAMB4FN1LAMA1LAMA2LAMA3LAMA4LAMA5LAMB1LAMB2LAMB3LAMC1LAMC2GSTO2GSTA5GSTA1GSTA2GSTA3GSTA4GSTM1GSTM2GSTM3GSTM4GSTM5GSTP1GSTT1GSTT2MGST1MGST2MGST3GSTT2BGSTO1GLI1GLI2GLI3


Description

draft pathway describing pathways in cancer

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View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. ''Pathways in cancer''; https://www.kegg.jp/dbget-bin/www_bget?pathway+hsa05200,

History

View all...
CompareRevisionActionTimeUserComment
135326view19:19, 21 August 2024Khanspersupdated kegg reference
135315view21:04, 19 August 2024Khanspersupdate KEGG ref
129459view01:04, 23 April 2024EweitzModified title
129136view16:45, 12 March 2024Khanspersminor tweak to test
128705view22:04, 20 February 2024EgonwMade a few pathways clickable
128257view00:14, 30 January 2024KhanspersModified description
128256view00:11, 30 January 2024Khanspersupdated lit ref
128254view00:08, 30 January 2024KhanspersOntology Term : 'cancer' added !
128253view00:08, 30 January 2024KhanspersOntology Term : 'altered signaling pathway' added !
128252view00:06, 30 January 2024Khanspersadded cell shape, legend, phospho sites
127898view00:17, 10 January 2024Khanspersnode sizing and layout
127897view00:08, 10 January 2024Khanspersadded cytokines and cytokine receptors
127896view22:57, 9 January 2024Khansperslayout
127895view22:51, 9 January 2024Khanspersadded wnts
127872view22:50, 3 January 2024Khansperslayout
127871view19:59, 3 January 2024Khansperscomplexes and interactions
127866view23:51, 2 January 2024Khanspersinteractions
127865view23:38, 2 January 2024Khanspersupdated interactions etc
127864view22:58, 2 January 2024Khansperslayout and interactions
127863view22:51, 2 January 2024Khanspersadded gst
127861view22:41, 2 January 2024Khanspersadded ecm
127859view22:33, 2 January 2024Khanspersadded wnt, fzd
127827view21:26, 21 December 2023KhanspersOntology Term : 'cancer pathway' added !
127826view21:25, 21 December 2023KhanspersModified title
127825view21:24, 21 December 2023KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
4-HNEMetaboliteC21642 (KEGG Compound)
ABL1GeneProductABL1 (HGNC)
ADCY1GeneProductADCY1 (HGNC)
ADCY2GeneProductADCY2 (HGNC)
ADCY3GeneProductADCY3 (HGNC)
ADCY4GeneProductADCY4 (HGNC)
ADCY5GeneProductADCY5 (HGNC)
ADCY6GeneProductADCY6 (HGNC)
ADCY7GeneProductADCY7 (HGNC)
ADCY8GeneProductADCY8 (HGNC)
ADCY9GeneProductADCY9 (HGNC)
AGTGeneProductAGT (HGNC)
AGTR1GeneProductAGTR1 (HGNC)
AKT1GeneProductAKT1 (HGNC)
AKT2GeneProductAKT2 (HGNC)
AKT3GeneProductAKT3 (HGNC)
ALKGeneProductALK (HGNC)
APAF1GeneProductAPAF1 (HGNC)
APC2GeneProductAPC2 (HGNC)
APCGeneProductAPC (HGNC)
APPL1GeneProductAPPL1 (HGNC)
ARAFGeneProductARAF (HGNC)
ARGeneProductAR (HGNC)
ARHGEF11GeneProductARHGEF11 (HGNC)
ARHGEF12GeneProductARHGEF12 (HGNC)
ARHGEF1GeneProductARHGEF1 (HGNC)
ARNT2GeneProductARNT2 (HGNC)
ARNTGeneProductARNT (HGNC)
AXIN1GeneProductAXIN1 (HGNC)
AXIN2GeneProductAXIN2 (HGNC)
AcroleinMetaboliteC01471 (KEGG Compound)
Adherens junctionPathway
AndrostenedioneMetaboliteHMDB00053 (HMDB)
ApoptosisPathwayWP254 (WikiPathways)
BADGeneProductBAD (HGNC)
BAK1GeneProductBAK1 (HGNC)
BAXGeneProductBAX (HGNC)
BBC3GeneProductBBC3 (HGNC)
BCL2GeneProductBCL2 (HGNC)
BCL2L11GeneProductBCL2L11 (HGNC)
BCL2L1GeneProductBCL2L1 (HGNC)
BCRGeneProductBCR (HGNC)
BDKRB1GeneProductBDKRB1 (HGNC)
BDKRB2GeneProductBDKRB2 (HGNC)
BIDGeneProductBID (HGNC)
BIRC2GeneProductBIRC2 (HGNC)
BIRC3GeneProductBIRC3 (HGNC)
BIRC5GeneProductBIRC5 (HGNC)
BIRC7GeneProductBIRC7 (HGNC)
BMP2GeneProductBMP2 (HGNC)
BMP4GeneProductBMP4 (HGNC)
BRAFGeneProductBRAF (HGNC)
BRCA2GeneProductBRCA2 (HGNC)
CALML1GeneProductCALML1 (HGNC)
CALML2GeneProductCALML2 (HGNC)
CALML3GeneProductCALML3 (HGNC)
CALML4GeneProductCALML4 (HGNC)
CALML5GeneProductCALML5 (HGNC)
CALML6GeneProductCALML6 (HGNC)
CAMK2AGeneProductCAMK2A (HGNC)
CAMK2BGeneProductCAMK2B (HGNC)
CAMK2DGeneProductCAMK2D (HGNC)
CAMK2GGeneProductCAMK2G (HGNC)
CASP3GeneProductCASP3 (HGNC)
CASP7GeneProductCASP7 (HGNC)
CASP8GeneProductCASP8 (HGNC)
CASP9GeneProductCASP9 (HGNC)
CBLGeneProductCBL (HGNC)
CCDC42GeneProductCCDC42 (HGNC)
CCDC6GeneProductCCDC6 (HGNC)
CCNA1GeneProductCCNA1 (HGNC)
CCNA2GeneProductCCNA2 (HGNC)
CCND1GeneProductCCND1 (HGNC)
CCND2GeneProductCCND2 (HGNC)
CCND3GeneProductCCND3 (HGNC)
CCNE1GeneProductCCNE1 (HGNC)
CCNE2GeneProductCCNE2 (HGNC)
CDH1GeneProductCDH1 (HGNC)
CDK2GeneProductCDK2 (HGNC)
CDK4GeneProductCDK4 (HGNC)
CDK6GeneProductCDK6 (HGNC)
CDKN1AGeneProductCDKN1A (HGNC)
CDKN1BGeneProductCDKN1B (HGNC)
CDKN2AGeneProductCDKN2A (HGNC)
CDKN2BGeneProductCDKN2B (HGNC)
CEBPAGeneProductCEBPA (HGNC)
CHUKGeneProductCHUK (HGNC)
CKS1BGeneProductCKS1B (HGNC)
COL4A1GeneProductCOL4A1 (HGNC)
COL4A2GeneProductCOL4A2 (HGNC)
COL4A3GeneProductCOL4A3 (HGNC)
COL4A4GeneProductCOL4A4 (HGNC)
COL4A5GeneProductCOL4A5 (HGNC)
COL4A6GeneProductCOL4A6 (HGNC)
CREBBPGeneProductCREBBP (HGNC)
CRKGeneProductCRK (HGNC)
CRKLGeneProductCRKL (HGNC)
CSF1RGeneProductCSF1R (HGNC)
CSF2RAGeneProductCSF2RA (HGNC)
CSF3RGeneProductCSF3R (HGNC)
CTBP1GeneProductCTBP1 (HGNC)
CTBP2GeneProductCTBP2 (HGNC)
CTNNA1GeneProductCTNNA1 (HGNC)
CTNNA2GeneProductCTNNA2 (HGNC)
CTNNA3GeneProductCTNNA3 (HGNC)
CTNNB1GeneProductCTNNB1 (HGNC)
CUL1GeneProductCUL1 (HGNC)
CUL2GeneProductCUL2 (HGNC)
CXCL12GeneProductCXCL12 (HGNC)
CXCL8GeneProductCXCL8 (HGNC)
CXCR4GeneProductCXCR4 (HGNC)
CYCSGeneProductCYCS (HGNC)
Ca2+MetaboliteCHEBI:29108 (ChEBI)
Calcium signaling pathwayPathway
Cell cyclePathwayWP179 (WikiPathways)
CholesterolMetaboliteHMDB00067 (HMDB)
CortisolMetaboliteHMDB00063 (HMDB)
CortisoneMetaboliteHMDB02802 (HMDB)
DAGMetaboliteC00165 (KEGG Compound)
DAPK1GeneProductDAPK1 (HGNC)
DAPK2GeneProductDAPK2 (HGNC)
DAPK3GeneProductDAPK3 (HGNC)
DCCGeneProductDCC (HGNC)
DDB2GeneProductDDB2 (HGNC)
DLL1GeneProductDLL1 (HGNC)
DLL3GeneProductDLL3 (HGNC)
DLL4GeneProductDLL4 (HGNC)
DNAMetaboliteCHEBI:16991 (ChEBI)
DVL1GeneProductDVL1 (HGNC)
DVL2GeneProductDVL2 (HGNC)
DVL3GeneProductDVL3 (HGNC)
DehydroepiandrosteroneMetaboliteHMDB00077 (HMDB)
DihydrotestosteroneMetaboliteHMDB02961 (HMDB)
E2F1GeneProductE2F1 (HGNC)
E2F2GeneProductE2F2 (HGNC)
E2F3GeneProductE2F3 (HGNC)
EDN1GeneProductEDN1 (HGNC)
EDNRAGeneProductEDNRA (HGNC)
EDNRBGeneProductEDNRB (HGNC)
EGFGeneProductEGF (HGNC)
EGFRGeneProductEGFR (HGNC)
EGLN1GeneProductEGLN1 (HGNC)
EGLN2GeneProductEGLN2 (HGNC)
EGLN3GeneProductEGLN3 (HGNC)
ELK1GeneProductELK1 (HGNC)
ELOBGeneProductELOB (HGNC)
ELOCGeneProductELOC (HGNC)
EML4GeneProductEML4 (HGNC)
EP300GeneProductEP300 (HGNC)
EPAS1GeneProductEPAS1 (HGNC)
ERBB2GeneProductERBB2 (HGNC)
ESR1GeneProductESR1 (HGNC)
ESR2GeneProductESR2 (HGNC)
ETS1GeneProductETS1 (HGNC)
EstradiolMetaboliteHMDB00151 (HMDB)
Estrogen signaling pathwayPathwayWP712 (WikiPathways)
F2GeneProductF2 (HGNC)
F2RGeneProductF2R (HGNC)
F2RL3GeneProductF2RL3 (HGNC)
FADDGeneProductFADD (HGNC)
FASGeneProductFAS (HGNC)
FASLGGeneProductFASLG (HGNC)
FGF1GeneProductFGF1 (HGNC)
FGFR1GeneProductFGFR1 (HGNC)
FGFR2GeneProductFGFR2 (HGNC)
FGFR3GeneProductFGFR3 (HGNC)
FGFR4GeneProductFGFR4 (HGNC)
FHGeneProductFH (HGNC)
FLT3GeneProductFLT3 (HGNC)
FLT3LGGeneProductFLT3LG (HGNC)
FLT4GeneProductFLT4 (HGNC)
FN1GeneProductFN1 (HGNC)
FOSGeneProductFOS (HGNC)
FOXO1GeneProductFOXO1 (HGNC)
FRAT1GeneProductFRAT1 (HGNC)
FRAT2GeneProductFRAT2 (HGNC)
FZD10GeneProductFZD10 (HGNC)
FZD1GeneProductFZD1 (HGNC)
FZD2GeneProductFZD2 (HGNC)
FZD3GeneProductFZD3 (HGNC)
FZD4GeneProductFZD4 (HGNC)
FZD5GeneProductFZD5 (HGNC)
FZD6GeneProductFZD6 (HGNC)
FZD7GeneProductFZD7 (HGNC)
FZD8GeneProductFZD8 (HGNC)
FZD9GeneProductFZD9 (HGNC)
FlutamideMetaboliteHMDB14642 (HMDB)
Focal adhesionPathwayWP306 (WikiPathways)
GADD45AGeneProductGADD45A (HGNC)
GADD45BGeneProductGADD45B (HGNC)
GADD45GGeneProductGADD45G (HGNC)
GLI1GeneProductGLI1 (HGNC)
GLI2GeneProductGLI2 (HGNC)
GLI3GeneProductGLI3 (HGNC)
GNA11GeneProductGNA11 (HGNC)
GNA12GeneProductGNA12 (HGNC)
GNA13GeneProductGNA13 (HGNC)
GNAI1GeneProductGNAI1 (HGNC)
GNAI2GeneProductGNAI2 (HGNC)
GNAI3GeneProductGNAI3 (HGNC)
GNAQGeneProductGNAQ (HGNC)
GNASGeneProductGNAS (HGNC)
GNB1GeneProductGNB1 (HGNC)
GNB2GeneProductGNB2 (HGNC)
GNB3GeneProductGNB3 (HGNC)
GNB4GeneProductGNB4 (HGNC)
GNB5GeneProductGNB5 (HGNC)
GNG10GeneProductGNG10 (HGNC)
GNG11GeneProductGNG11 (HGNC)
GNG12GeneProductGNG12 (HGNC)
GNG13GeneProductGNG13 (HGNC)
GNG2GeneProductGNG2 (HGNC)
GNG3GeneProductGNG3 (HGNC)
GNG4GeneProductGNG4 (HGNC)
GNG5GeneProductENSG00000174021 (Ensembl)
GNG7GeneProductGNG7 (HGNC)
GNG8GeneProductGNG8 (HGNC)
GNGT1GeneProductGNGT1 (HGNC)
GNGT2GeneProductGNGT2 (HGNC)
GRB2GeneProductGRB2 (HGNC)
GSK3BGeneProductGSK3B (HGNC)
GSTA1GeneProductGSTA1 (HGNC)
GSTA2GeneProductGSTA2 (HGNC)
GSTA3GeneProductGSTA3 (HGNC)
GSTA4GeneProductGSTA4 (HGNC)
GSTA5GeneProductGSTA5 (HGNC)
GSTM1GeneProductGSTM1 (HGNC)
GSTM2GeneProductGSTM2 (HGNC)
GSTM3GeneProductGSTM3 (HGNC)
GSTM4GeneProductGSTM4 (HGNC)
GSTM5GeneProductGSTM5 (HGNC)
GSTO1GeneProductGSTO1 (HGNC)
GSTO2GeneProductGSTO2 (HGNC)
GSTP1GeneProductGSTP1 (HGNC)
GSTT1GeneProductGSTT1 (HGNC)
GSTT2BGeneProductGSTT2B (HGNC)
GSTT2GeneProductGSTT2 (HGNC)
HDAC1GeneProductHDAC1 (HGNC)
HDAC2GeneProductHDAC2 (HGNC)
HES1GeneProductHES1 (HGNC)
HES5GeneProductHES5 (HGNC)
HEY1GeneProductHEY1 (HGNC)
HEY2GeneProductHEY2 (HGNC)
HEYLGeneProductHEYL (HGNC)
HGFGeneProductHGF (HGNC)
HHIPGeneProductHHIP (HGNC)
HIF-1 signaling pathwayPathway
HIF1AGeneProductHIF1A (HGNC)
HMOX1GeneProductHMOX1 (HGNC)
HRASGeneProductHRAS (HGNC)
HSP90AA1GeneProductHSP90AA1 (HGNC)
HSP90AB1GeneProductHSP90AB1 (HGNC)
HSP90B1GeneProductHSP90B1 (HGNC)
Hedgehog signaling pathwayPathwayWP4249 (WikiPathways)
Hydrogen peroxideMetaboliteHMDB03125 (HMDB)
Hydroperoxyl radicalMetaboliteC21641 (ChEMBL compound)
Hydroxyl radicalMetaboliteC16844 (KEGG Compound)
IGF1GeneProductIGF1 (HGNC)
IGF1RGeneProductIGF1R (HGNC)
IGF2GeneProductIGF2 (HGNC)
IKBKBGeneProductIKBKB (HGNC)
IKBKGGeneProductIKBKG (HGNC)
IL6GeneProductIL6 (HGNC)
IP3MetaboliteC01245 (KEGG Compound)
ITGA2BGeneProductITGA2B (HGNC)
ITGA2GeneProductITGA2 (HGNC)
ITGA3GeneProductITGA3 (HGNC)
ITGA6GeneProductITGA6 (HGNC)
ITGAVGeneProductITGAV (HGNC)
ITGB1GeneProductITGB1 (HGNC)
JAG1GeneProductJAG1 (HGNC)
JAG2GeneProductJAG2 (HGNC)
JAK1GeneProductJAK1 (HGNC)
JAK2GeneProductJAK2 (HGNC)
JAK3GeneProductJAK3 (HGNC)
JUNGeneProductJUN (HGNC)
JUPGeneProductJUP (HGNC)
Jak-STAT signaling pathwayPathway
KEAP1GeneProductKEAP1 (HGNC)
KIF7GeneProductKIF7 (HGNC)
KITGeneProductKIT (HGNC)
KITLGGeneProductKITLG (HGNC)
KLK3GeneProductKLK3 (HGNC)
KNG1GeneProductKNG1 (HGNC)
KRASGeneProductKRAS (HGNC)
LAMA1GeneProductLAMA1 (HGNC)
LAMA2GeneProductLAMA2 (HGNC)
LAMA3GeneProductLAMA3 (HGNC)
LAMA4GeneProductLAMA4 (HGNC)
LAMA5GeneProductLAMA5 (HGNC)
LAMB1GeneProductLAMB1 (HGNC)
LAMB2GeneProductLAMB2 (HGNC)
LAMB3GeneProductLAMB3 (HGNC)
LAMB4GeneProductLAMB4 (HGNC)
LAMC1GeneProductLAMC1 (HGNC)
LAMC2GeneProductLAMC2 (HGNC)
LAMC3GeneProductLAMC3 (HGNC)
LEF1GeneProductLEF1 (HGNC)
LPAR1GeneProductLPAR1 (HGNC)
LPAR2GeneProductLPAR2 (HGNC)
LPAR3GeneProductLPAR3 (HGNC)
LPAR4GeneProductLPAR4 (HGNC)
LPAR5GeneProductLPAR5 (HGNC)
LPAR6GeneProductLPAR6 (HGNC)
LRP5GeneProductLRP5 (HGNC)
LRP6GeneProductLRP6 (HGNC)
MAP2K1GeneProductMAP2K1 (HGNC)
MAP2K2GeneProductMAP2K2 (HGNC)
MAPK signaling pathwayPathwayWP382 (WikiPathways)
MAPK10GeneProductMAPK10 (HGNC)
MAPK1GeneProductMAPK1 (HGNC)
MAPK3GeneProductMAPK3 (HGNC)
MAPK8GeneProductMAPK8 (HGNC)
MAPK9GeneProductMAPK9 (HGNC)
MAXGeneProductMAX (HGNC)
MDM2GeneProductMDM2 (HGNC)
MECOMGeneProductMECOM (HGNC)
METGeneProductMET (HGNC)
MGST1GeneProductMGST1 (HGNC)
MGST2GeneProductMGST2 (HGNC)
MGST3GeneProductMGST3 (HGNC)
MITFGeneProductMITF (HGNC)
MLH1GeneProductMLH1 (HGNC)
MMP1GeneProductMMP1 (HGNC)
MMP2GeneProductMMP2 (HGNC)
MMP3GeneProductMMP3 (HGNC)
MSH2GeneProductMSH2 (HGNC)
MSH3GeneProductMSH3 (HGNC)
MSH6GeneProductMSH6 (HGNC)
MST1GeneProductMST1 (HGNC)
MTORGeneProductMTOR (HGNC)
MYCGeneProductMYC (HGNC)
MalateMetaboliteCHEBI:30797 (ChEBI)
NCOA1GeneProductNCOA1 (HGNC)
NCOA3GeneProductNCOA3 (HGNC)
NCOA4GeneProductNCOA4 (HGNC)
NFE2L2GeneProductNFE2L2 (HGNC)
NFKB1GeneProductNFKB1 (HGNC)
NFKB2GeneProductNFKB2 (HGNC)
NFKBIAGeneProductNFKBIA (HGNC)
NKX3-1GeneProductNKX3-1 (HGNC)
NOS2GeneProductNOS2 (HGNC)
NOTCH1GeneProductNOTCH1 (HGNC)
NOTCH2GeneProductNOTCH2 (HGNC)
NOTCH3GeneProductNOTCH3 (HGNC)
NOTCH4GeneProductNOTCH4 (HGNC)
NQO1GeneProductNQO1 (HGNC)
NRASGeneProductNRAS (HGNC)
NTRK1GeneProductNTRK1 (HGNC)
Nitric oxideMetaboliteHMDB03378 (HMDB)
Notch signaling pathwayPathwayWP268 (WikiPathways)
PAMetaboliteC00416 (KEGG Compound)
PAX8GeneProductPAX8 (HGNC)
PDGFAGeneProductPDGFA (HGNC)
PDGFBGeneProductPDGFB (HGNC)
PDGFRAGeneProductPDGFRA (HGNC)
PDGFRBGeneProductPDGFRB (HGNC)
PGE2MetaboliteHMDB01220 (HMDB)
PGFGeneProductPGF (HGNC)
PI3K-Akt signaling pathwayPathwayWP4172 (KEGG Pathway)
PIK3CAGeneProductPIK3CA (HGNC)
PIK3CBGeneProductPIK3CB (HGNC)
PIK3CDGeneProductPIK3CD (HGNC)
PIK3R1GeneProductPIK3R1 (HGNC)
PIK3R2GeneProductPIK3R2 (HGNC)
PIK3R3GeneProductPIK3R3 (HGNC)
PIM1GeneProductPIM1 (HGNC)
PIM2GeneProductPIM2 (HGNC)
PIP3MetaboliteC05981 (KEGG Compound)
PLCB1GeneProductPLCB1 (HGNC)
PLCB2GeneProductPLCB2 (HGNC)
PLCB3GeneProductPLCB3 (HGNC)
PLCB4GeneProductPLCB4 (HGNC)
PLCG1GeneProductPLCG1 (HGNC)
PLCG2GeneProductPLCG2 (HGNC)
PLD1GeneProductPLD1 (HGNC)
PLD2GeneProductPLD2 (HGNC)
PLEKHG5GeneProductPLEKHG5 (HGNC)
PMAIP1GeneProductPMAIP1 (HGNC)
PMLGeneProductPML (HGNC)
POLKGeneProductPOLK (HGNC)
PPAR signaling pathwayPathwayWP3942 (WikiPathways)
PPARDGeneProductPPARD (HGNC)
PPARGGeneProductPPARG (HGNC)
PRKACAGeneProductPRKACA (HGNC)
PRKACBGeneProductPRKACB (HGNC)
PRKACGGeneProductPRKACG (HGNC)
PRKCAGeneProductPRKCA (HGNC)
PRKCBGeneProductPRKCB (HGNC)
PRKCGGeneProductPRKCG (HGNC)
PTCH1GeneProductPTCH1 (HGNC)
PTCH2GeneProductPTCH2 (HGNC)
PTENGeneProductPTEN (HGNC)
PTGER1GeneProductPTGER1 (HGNC)
PTGER2GeneProductPTGER2 (HGNC)
PTGER3GeneProductPTGER3 (HGNC)
PTGER4GeneProductPTGER4 (HGNC)
PTGS2GeneProductPTGS2 (HGNC)
PTK2GeneProductPTK2 (HGNC)
ProgesteroneMetaboliteHMDB01830 (HMDB)
RAC1GeneProductRAC1 (HGNC)
RAC2GeneProduct5880 (Entrez Gene)
RAC3GeneProductRAC3 (HGNC)
RAD51GeneProductRAD51 (HGNC)
RAF1GeneProductRAF1 (HGNC)
RALAGeneProductRALA (HGNC)
RALBP1GeneProductRALBP1 (HGNC)
RALBGeneProductRALB (HGNC)
RALGDSGeneProductRALGDS (HGNC)
RARAGeneProductRARA (HGNC)
RARBGeneProductRARB (HGNC)
RASGRP1GeneProductRASGRP1 (HGNC)
RASGRP2GeneProductRASGRP2 (HGNC)
RASGRP3GeneProductRASGRP3 (HGNC)
RASGRP4GeneProductRASGRP4 (HGNC)
RASSF1GeneProductRASSF1 (HGNC)
RASSF5GeneProductRASSF5 (HGNC)
RB1GeneProductRB1 (HGNC)
RBX1GeneProductRBX1 (HGNC)
RELAGeneProductRELA (HGNC)
RETGeneProductRET (HGNC)
RHOAGeneProductRHOA (HGNC)
ROCK1GeneProductROCK1 (HGNC)
ROCK2GeneProductROCK2 (HGNC)
RPS6KA5GeneProductRPS6KA5 (HGNC)
RPS6KB1GeneProductRPS6KB1 (HGNC)
RPS6KB2GeneProductRPS6KB2 (HGNC)
RUNX1GeneProductRUNX1 (HGNC)
RUNX1T1GeneProductRUNX1T1 (HGNC)
RXRAGeneProductRXRA (HGNC)
RXRBGeneProductRXRB (HGNC)
RXRGGeneProductRXRG (HGNC)
Retinoic AcidMetaboliteCHEBI:15367 (ChEBI)
SHHGeneProductSHH (HGNC)
SKP1GeneProductSKP1 (HGNC)
SKP2GeneProductSKP2 (HGNC)
SLC2A1GeneProductSLC2A1 (HGNC)
SMAD2GeneProductSMAD2 (HGNC)
SMAD3GeneProductSMAD3 (HGNC)
SMAD4GeneProductSMAD4 (HGNC)
SMOGeneProductSMO (HGNC)
SOS1GeneProductSOS1 (HGNC)
SOS2GeneProductSOS2 (HGNC)
SP1GeneProductENSG00000185591 (Ensembl)
SPI1GeneProductSPI1 (HGNC)
STAT1GeneProductSTAT1 (HGNC)
STAT2GeneProductSTAT2 (HGNC)
STAT3GeneProductSTAT3 (HGNC)
STAT4GeneProductSTAT4 (HGNC)
STAT5AGeneProductSTAT5A (HGNC)
STAT5BGeneProductSTAT5B (HGNC)
STAT6GeneProductSTAT6 (HGNC)
SUFUGeneProductSUFU (HGNC)
SuperoxideMetaboliteHMDB02168 (HMDB)
TCF7L1GeneProductTCF7L1 (HGNC)
TCF7L2GeneProductTCF7L2 (HGNC)
TCF7GeneProductTCF7 (HGNC)
TERCGeneProductTERC (HGNC)
TERTGeneProductTERT (HGNC)
TFGGeneProductTFG (HGNC)
TGF-beta signaling pathwayPathwayWP560 (WikiPathways)
TGFAGeneProductTGFA (HGNC)
TGFB1GeneProductTGFB1 (HGNC)
TGFB2GeneProductTGFB2 (HGNC)
TGFB3GeneProductTGFB3 (HGNC)
TGFBR1GeneProductTGFBR1 (HGNC)
TGFBR2GeneProductTGFBR2 (HGNC)
TP53GeneProductTP53 (HGNC)
TPM3GeneProductTPM3 (HGNC)
TPRGeneProductTPR (HGNC)
TRAF1GeneProductTRAF1 (HGNC)
TRAF2GeneProductTRAF2 (HGNC)
TRAF3GeneProductTRAF3 (HGNC)
TRAF4GeneProductTRAF4 (HGNC)
TRAF5GeneProductTRAF5 (HGNC)
TRAF6GeneProductTRAF6 (HGNC)
TXNRD1GeneProductTXNRD1 (HGNC)
TXNRD2GeneProductTXNRD2 (HGNC)
TXNRD3GeneProductTXNRD3 (HGNC)
TestosteroneMetaboliteHMDB00234 (HMDB)
VEGF signaling pathwayPathwayWP3888 (WikiPathways)
VEGFAGeneProductVEGFA (HGNC)
VEGFBGeneProductVEGFB (HGNC)
VEGFCGeneProductVEGFC (HGNC)
VEGFDGeneProductVEGFD (HGNC)
VHLGeneProductVHL (HGNC)
WNT10AGeneProductWNT10A (HGNC)
WNT10BGeneProductWNT10B (HGNC)
WNT11GeneProductWNT11 (HGNC)
WNT16GeneProductWNT16 (HGNC)
WNT1GeneProductWNT1 (HGNC)
WNT2BGeneProductWNT2B (HGNC)
WNT2GeneProductWNT2 (HGNC)
WNT3AGeneProductWNT3A (HGNC)
WNT3GeneProductWNT3 (HGNC)
WNT4GeneProductWNT4 (HGNC)
WNT5AGeneProductWNT5A (HGNC)
WNT5BGeneProductWNT5B (HGNC)
WNT6GeneProductWNT6 (HGNC)
WNT7AGeneProductWNT7A (HGNC)
WNT7BGeneProductWNT7B (HGNC)
WNT8AGeneProductWNT8A (HGNC)
WNT8BGeneProductWNT8B (HGNC)
WNT9AGeneProductWNT9A (HGNC)
WNT9BGeneProductWNT9B (HGNC)
Wnt signaling pathwayPathwayWP428 (WikiPathways)
XIAPGeneProductXIAP (HGNC)
ZBTB16GeneProductZBTB16 (HGNC)
ZBTB17GeneProductZBTB17 (HGNC)
cAMP signaling pathwayPathway
cAMPMetaboliteCHEBI:17489 (ChEBI)
fumarateMetaboliteCHEBI:29806 (ChEBI)
mTOR signaling pathwayPathwayWP3932 (WikiPathways)
p53 signaling pathwayPathway

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5434"
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