Cancer pathways (Homo sapiens)

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Revision as of 19:59, 3 January 2024 by Khanspers (Talk | contribs)
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MitochondriaMicrotubuleDNA damageLigandsTelomeric DNA repeatsCytokine receptorRARatarget genesWntPU.1 target genes?SustainedangiogenesisOxidative or electrophilic stressCarcinogensSPI1PIP3BAXVEGFDBBC3CCND1MECOMCYCSCHUKGLI1CASP9Focal adhesionEGFSTAT5AABL1IGF1CDKN1AmTOR signalingpathwayPACTNNA1Hydroperoxyl radicalTGFALRP5Calcium signalingpathwayCSF1RIGF1RHedgehog signaling pathwayHydroxyl radicalSTAT1RARBNOTCH1RUNX1TP53FASLGKITCASP3FADDADCY1BMP2ZBTB17RALBP1RASGRP1KITLGGNASCell cycleMSH6MLH1FGFR1PI3K-Aktsignaling pathwayNFKB1SPI1CREBBPGADD45GRASSF5ALKJUPRPS6KB1GNA13PLCG1CDK4BIDMETTERTGNA11CASP3LEF1ARHGEF12RAD51RHOADAPK1RHOAPPAR signalingpathwayFRAT1MYCCDH1KIF7ETS1PMAIP1CASP8CholesterolPGFcAMP signalingpathwayTXNRD1CCND1MITFCDK2NFKBIAcAMPPDGFRASTAT3BCL2L11RASSF1POLKDNARASSF1EstradiolMAP2K1FLT4ELOBGSTP1APC2MYCCTNNB1EstradiolPRKACACSF3RROCK1GNAI1CXCL8TestosteroneTGF-beta signalingpathwayKEAP1NOS2RBX1TGFBR1CRKProgesteroneAGTGRB2FLT3NCOA3AcroleinFOXO1PPARDARAFPTK2RPS6KA5RXRACDKN2AHydrogen peroxideBCL2FASCCNA2HHIPGNB5PIK3CAFLT3LGBIRC5EPAS1NKX3-1SOS1CDKN2BRUNX1SMAD4MSH2DCCBCL2EDN1MSH3BIRC2EGLN2ESR1IP3MMP1TGFB1Estrogen signalingpathwayRB1Nitric oxideEDNRACXCR4MAPK signalingpathwayRetinoic AcidApoptosisPDGFBDDB2Jak-STAT signaling pathwayWNT16MAPK1CTNNB1APAF1CTBP1JAK1SMAD2BADMAXHSP90AA1fumarateITGB1PLD1PTGER1PTENp53 signalingpathwayCDKN1BRARATGFAPTGS2CDKN1ASLC2A1TGFBR2HES1BAK1MDM2ELK1CCND1PTCH1Wnt signalingpathwayMYCF2HMOX1CCNE1IP3SKP2KNG1DehydroepiandrosteroneCALML1DVL1DAGCKS1BVEGF signalingpathwaySMONFE2L2RAC1STAT2LPAR6CDKN1BGSK3BNQO1RETSUFUCEBPAERBB2JAG1SHHCTNNB1TGFB1HRASPTCH1ITGA6APPL1ARBRCA2BCL2L1TRAF1BAK1CASP3CDKN2AARNTBCL2L1MTORMYCPRKCACDK4CUL2Ca2+Notch signaling pathwayPLCB1ELOCDLL3CXCL12CSF2RAKLK3FHBAXPDGFABADRALGDSPIM2AXIN1TGFBR2SuperoxideTP53TFGEGFRE2F1Adherens junctionIL6FOSHIF-1 signalingpathwayHDAC1VHLHGFTERCPGE2CASP9SKP1JUNMDM2HEY1RALACAMK2AFGF1PMLPPARGMAPK8PJAG2DLL4DLL1GLI2GLI3DihydrotestosteroneFlutamideAndrostenedioneCortisolCortisoneARHSP90AB1HSP90B1ARNOTCH2NOTCH3NOTCH4BMP4GLI1PTCH2HES5HEY2HEYLEGLN1EGLN3MalateHIF1AARNT2EP300VEGFAVEGFBVEGFCTGFB2TGFB34-HNETXNRD2TXNRD3CASP7Evaiding apoptosisMitochondriaTGFB2TGFB3SMAD3Genomic damageInsesitivity toanti-growth signalsResistance tochemotherapyImmortalityHDAC2CTBP2DNAGenomic instabilityGADD45BGADD45ACDK6CCND2CCND3E2F2E2F3ProliferationCCNE2RBX1CUL1CKS1BBlock ofdifferentiationE2F1E2F2E2F3CSF1RCSF1RC/EBPa target genesAML1 target genesRARAZBTB16RUNX1RUNX1T1CCNA1CCND1TCF7TCF7L2TCF7L1SP1ESR2NCOA1ESR1ESR2EstradiolEstradiolRXRBRXRGRXRARXRBRXRGPPARGPAX8CCND1VEGFDVEGFAVEGFBVEGFCMMP2MMP3FOSMYCJUNMAPK3DAPK2DAPK3MAP2K2BRAFRAF1NRASKRASSOS2ERBB2PDGFRBFGFR2FGFR3FGFR4Cytokine IGF2PDGFBRALBPLD2RAC2RAC3MAPK9MAPK10RAC1RAC2RAC3CCDC42PLCG2EML4PRKCBPRKCGCCDC6NCOA4NTRK1TPM3TPRTissue invasion and metastasisCTNNA3CTNNA2AXIN2APCFRAT2DVL2DVL3MYCCCND1LEF1TCF7TCF7L2TCF7L1PGFVEGFDVEGFAVEGFBVEGFCLRP6PTGER2PTGER3PTGER4AGTR1LPAR1F2RLPAR2LPAR3LPAR4LPAR5F2RL3GNA12ARHGEF11ARHGEF1PLEKHG5ROCK2GNAI2GNAI3ADCY2ADCY3ADCY4ADCY5ADCY6ADCY7ADCY8ADCY9PRKACBPRKACGGNB1GNB2GNB3GNG3GNG4GNG5GNG7GNG10GNG11GNGT1BCL2L1PIM1BIRC3BIRC7XIAPTRAF2TRAF3TRAF4TRAF5TRAF6GNGT2GNG13GNG2GNG12GNG8GNB4ITGA2ITGA2BITGA3ITGAVEDNRBF2AGTBDKRB1BDKRB2GNAQPLCB2PLCB3PLCB4PRKCAPRKCBPRKCGCa2+DAGJAK2JAK3RASGRP2RASGRP3RASGRP4ALKEML4MST1STAT5BSTAT4STAT6BCRCBLCRKLPIK3CBPIK3CDPIK3R1PIK3R2PIK3R3AKT1AKT2AKT3IKBKBIKBKGNFKB2RELACASP9BCL2L1RPS6KB2CALML2CALML3CALML4CALML5CALML6CAMK2BCAMK2DCAMK2GWNT4WNT1WNT2WNT3WNT5AWNT6WNT7AWNT7BWNT8AWNT8BWNT10BWNT11WNT2BWNT9AWNT9BWNT10AWNT5BWNT3AFZD10FZD2FZD5FZD3FZD1FZD4FZD6FZD7FZD8FZD9LAMC3COL4A1COL4A2COL4A3COL4A4COL4A5COL4A6LAMB4FN1LAMA1LAMA2LAMA3LAMA4LAMA5LAMB1LAMB2LAMB3LAMC1LAMC2GSTO2GSTA5GSTA1GSTA2GSTA3GSTA4GSTM1GSTM2GSTM3GSTM4GSTM5GSTP1GSTT1GSTT2MGST1MGST2MGST3GSTT2BGSTO1GLI1GLI2GLI3


Description

draft pathway describing pathways in cancer

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View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. ''Pathways in cancer''; https://www.kegg.jp/dbget-bin/www_bget?pathway+hsa05200,

History

View all...
CompareRevisionActionTimeUserComment
135326view19:19, 21 August 2024Khanspersupdated kegg reference
135315view21:04, 19 August 2024Khanspersupdate KEGG ref
129459view01:04, 23 April 2024EweitzModified title
129136view16:45, 12 March 2024Khanspersminor tweak to test
128705view22:04, 20 February 2024EgonwMade a few pathways clickable
128257view00:14, 30 January 2024KhanspersModified description
128256view00:11, 30 January 2024Khanspersupdated lit ref
128254view00:08, 30 January 2024KhanspersOntology Term : 'cancer' added !
128253view00:08, 30 January 2024KhanspersOntology Term : 'altered signaling pathway' added !
128252view00:06, 30 January 2024Khanspersadded cell shape, legend, phospho sites
127898view00:17, 10 January 2024Khanspersnode sizing and layout
127897view00:08, 10 January 2024Khanspersadded cytokines and cytokine receptors
127896view22:57, 9 January 2024Khansperslayout
127895view22:51, 9 January 2024Khanspersadded wnts
127872view22:50, 3 January 2024Khansperslayout
127871view19:59, 3 January 2024Khansperscomplexes and interactions
127866view23:51, 2 January 2024Khanspersinteractions
127865view23:38, 2 January 2024Khanspersupdated interactions etc
127864view22:58, 2 January 2024Khansperslayout and interactions
127863view22:51, 2 January 2024Khanspersadded gst
127861view22:41, 2 January 2024Khanspersadded ecm
127859view22:33, 2 January 2024Khanspersadded wnt, fzd
127827view21:26, 21 December 2023KhanspersOntology Term : 'cancer pathway' added !
127826view21:25, 21 December 2023KhanspersModified title
127825view21:24, 21 December 2023KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
4-HNEMetaboliteC21642 (KEGG Compound)
ABL1GeneProductABL1 (HGNC)
ADCY1GeneProductADCY1 (HGNC)
ADCY2GeneProductADCY2 (HGNC)
ADCY3GeneProductADCY3 (HGNC)
ADCY4GeneProductADCY4 (HGNC)
ADCY5GeneProductADCY5 (HGNC)
ADCY6GeneProductADCY6 (HGNC)
ADCY7GeneProductADCY7 (HGNC)
ADCY8GeneProductADCY8 (HGNC)
ADCY9GeneProductADCY9 (HGNC)
AGTGeneProductAGT (HGNC)
AGTR1GeneProductAGTR1 (HGNC)
AKT1GeneProductAKT1 (HGNC)
AKT2GeneProductAKT2 (HGNC)
AKT3GeneProductAKT3 (HGNC)
ALKGeneProductALK (HGNC)
APAF1GeneProductAPAF1 (HGNC)
APC2GeneProductAPC2 (HGNC)
APCGeneProductAPC (HGNC)
APPL1GeneProductAPPL1 (HGNC)
ARAFGeneProductARAF (HGNC)
ARGeneProductAR (HGNC)
ARHGEF11GeneProductARHGEF11 (HGNC)
ARHGEF12GeneProductARHGEF12 (HGNC)
ARHGEF1GeneProductARHGEF1 (HGNC)
ARNT2GeneProductARNT2 (HGNC)
ARNTGeneProductARNT (HGNC)
AXIN1GeneProductAXIN1 (HGNC)
AXIN2GeneProductAXIN2 (HGNC)
AcroleinMetaboliteC01471 (KEGG Compound)
Adherens junctionPathway
AndrostenedioneMetaboliteHMDB00053 (HMDB)
ApoptosisPathwayWP254 (WikiPathways)
BADGeneProductBAD (HGNC)
BAK1GeneProductBAK1 (HGNC)
BAXGeneProductBAX (HGNC)
BBC3GeneProductBBC3 (HGNC)
BCL2GeneProductBCL2 (HGNC)
BCL2L11GeneProductBCL2L11 (HGNC)
BCL2L1GeneProductBCL2L1 (HGNC)
BCRGeneProductBCR (HGNC)
BDKRB1GeneProductBDKRB1 (HGNC)
BDKRB2GeneProductBDKRB2 (HGNC)
BIDGeneProductBID (HGNC)
BIRC2GeneProductBIRC2 (HGNC)
BIRC3GeneProductBIRC3 (HGNC)
BIRC5GeneProductBIRC5 (HGNC)
BIRC7GeneProductBIRC7 (HGNC)
BMP2GeneProductBMP2 (HGNC)
BMP4GeneProductBMP4 (HGNC)
BRAFGeneProductBRAF (HGNC)
BRCA2GeneProductBRCA2 (HGNC)
CALML1GeneProductCALML1 (HGNC)
CALML2GeneProductCALML2 (HGNC)
CALML3GeneProductCALML3 (HGNC)
CALML4GeneProductCALML4 (HGNC)
CALML5GeneProductCALML5 (HGNC)
CALML6GeneProductCALML6 (HGNC)
CAMK2AGeneProductCAMK2A (HGNC)
CAMK2BGeneProductCAMK2B (HGNC)
CAMK2DGeneProductCAMK2D (HGNC)
CAMK2GGeneProductCAMK2G (HGNC)
CASP3GeneProductCASP3 (HGNC)
CASP7GeneProductCASP7 (HGNC)
CASP8GeneProductCASP8 (HGNC)
CASP9GeneProductCASP9 (HGNC)
CBLGeneProductCBL (HGNC)
CCDC42GeneProductCCDC42 (HGNC)
CCDC6GeneProductCCDC6 (HGNC)
CCNA1GeneProductCCNA1 (HGNC)
CCNA2GeneProductCCNA2 (HGNC)
CCND1GeneProductCCND1 (HGNC)
CCND2GeneProductCCND2 (HGNC)
CCND3GeneProductCCND3 (HGNC)
CCNE1GeneProductCCNE1 (HGNC)
CCNE2GeneProductCCNE2 (HGNC)
CDH1GeneProductCDH1 (HGNC)
CDK2GeneProductCDK2 (HGNC)
CDK4GeneProductCDK4 (HGNC)
CDK6GeneProductCDK6 (HGNC)
CDKN1AGeneProductCDKN1A (HGNC)
CDKN1BGeneProductCDKN1B (HGNC)
CDKN2AGeneProductCDKN2A (HGNC)
CDKN2BGeneProductCDKN2B (HGNC)
CEBPAGeneProductCEBPA (HGNC)
CHUKGeneProductCHUK (HGNC)
CKS1BGeneProductCKS1B (HGNC)
COL4A1GeneProductCOL4A1 (HGNC)
COL4A2GeneProductCOL4A2 (HGNC)
COL4A3GeneProductCOL4A3 (HGNC)
COL4A4GeneProductCOL4A4 (HGNC)
COL4A5GeneProductCOL4A5 (HGNC)
COL4A6GeneProductCOL4A6 (HGNC)
CREBBPGeneProductCREBBP (HGNC)
CRKGeneProductCRK (HGNC)
CRKLGeneProductCRKL (HGNC)
CSF1RGeneProductCSF1R (HGNC)
CSF2RAGeneProductCSF2RA (HGNC)
CSF3RGeneProductCSF3R (HGNC)
CTBP1GeneProductCTBP1 (HGNC)
CTBP2GeneProductCTBP2 (HGNC)
CTNNA1GeneProductCTNNA1 (HGNC)
CTNNA2GeneProductCTNNA2 (HGNC)
CTNNA3GeneProductCTNNA3 (HGNC)
CTNNB1GeneProductCTNNB1 (HGNC)
CUL1GeneProductCUL1 (HGNC)
CUL2GeneProductCUL2 (HGNC)
CXCL12GeneProductCXCL12 (HGNC)
CXCL8GeneProductCXCL8 (HGNC)
CXCR4GeneProductCXCR4 (HGNC)
CYCSGeneProductCYCS (HGNC)
Ca2+MetaboliteCHEBI:29108 (ChEBI)
Calcium signaling pathwayPathway
Cell cyclePathwayWP179 (WikiPathways)
CholesterolMetaboliteHMDB00067 (HMDB)
CortisolMetaboliteHMDB00063 (HMDB)
CortisoneMetaboliteHMDB02802 (HMDB)
DAGMetaboliteC00165 (KEGG Compound)
DAPK1GeneProductDAPK1 (HGNC)
DAPK2GeneProductDAPK2 (HGNC)
DAPK3GeneProductDAPK3 (HGNC)
DCCGeneProductDCC (HGNC)
DDB2GeneProductDDB2 (HGNC)
DLL1GeneProductDLL1 (HGNC)
DLL3GeneProductDLL3 (HGNC)
DLL4GeneProductDLL4 (HGNC)
DNAMetaboliteCHEBI:16991 (ChEBI)
DVL1GeneProductDVL1 (HGNC)
DVL2GeneProductDVL2 (HGNC)
DVL3GeneProductDVL3 (HGNC)
DehydroepiandrosteroneMetaboliteHMDB00077 (HMDB)
DihydrotestosteroneMetaboliteHMDB02961 (HMDB)
E2F1GeneProductE2F1 (HGNC)
E2F2GeneProductE2F2 (HGNC)
E2F3GeneProductE2F3 (HGNC)
EDN1GeneProductEDN1 (HGNC)
EDNRAGeneProductEDNRA (HGNC)
EDNRBGeneProductEDNRB (HGNC)
EGFGeneProductEGF (HGNC)
EGFRGeneProductEGFR (HGNC)
EGLN1GeneProductEGLN1 (HGNC)
EGLN2GeneProductEGLN2 (HGNC)
EGLN3GeneProductEGLN3 (HGNC)
ELK1GeneProductELK1 (HGNC)
ELOBGeneProductELOB (HGNC)
ELOCGeneProductELOC (HGNC)
EML4GeneProductEML4 (HGNC)
EP300GeneProductEP300 (HGNC)
EPAS1GeneProductEPAS1 (HGNC)
ERBB2GeneProductERBB2 (HGNC)
ESR1GeneProductESR1 (HGNC)
ESR2GeneProductESR2 (HGNC)
ETS1GeneProductETS1 (HGNC)
EstradiolMetaboliteHMDB00151 (HMDB)
Estrogen signaling pathwayPathwayWP712 (WikiPathways)
F2GeneProductF2 (HGNC)
F2RGeneProductF2R (HGNC)
F2RL3GeneProductF2RL3 (HGNC)
FADDGeneProductFADD (HGNC)
FASGeneProductFAS (HGNC)
FASLGGeneProductFASLG (HGNC)
FGF1GeneProductFGF1 (HGNC)
FGFR1GeneProductFGFR1 (HGNC)
FGFR2GeneProductFGFR2 (HGNC)
FGFR3GeneProductFGFR3 (HGNC)
FGFR4GeneProductFGFR4 (HGNC)
FHGeneProductFH (HGNC)
FLT3GeneProductFLT3 (HGNC)
FLT3LGGeneProductFLT3LG (HGNC)
FLT4GeneProductFLT4 (HGNC)
FN1GeneProductFN1 (HGNC)
FOSGeneProductFOS (HGNC)
FOXO1GeneProductFOXO1 (HGNC)
FRAT1GeneProductFRAT1 (HGNC)
FRAT2GeneProductFRAT2 (HGNC)
FZD10GeneProductFZD10 (HGNC)
FZD1GeneProductFZD1 (HGNC)
FZD2GeneProductFZD2 (HGNC)
FZD3GeneProductFZD3 (HGNC)
FZD4GeneProductFZD4 (HGNC)
FZD5GeneProductFZD5 (HGNC)
FZD6GeneProductFZD6 (HGNC)
FZD7GeneProductFZD7 (HGNC)
FZD8GeneProductFZD8 (HGNC)
FZD9GeneProductFZD9 (HGNC)
FlutamideMetaboliteHMDB14642 (HMDB)
Focal adhesionPathwayWP306 (WikiPathways)
GADD45AGeneProductGADD45A (HGNC)
GADD45BGeneProductGADD45B (HGNC)
GADD45GGeneProductGADD45G (HGNC)
GLI1GeneProductGLI1 (HGNC)
GLI2GeneProductGLI2 (HGNC)
GLI3GeneProductGLI3 (HGNC)
GNA11GeneProductGNA11 (HGNC)
GNA12GeneProductGNA12 (HGNC)
GNA13GeneProductGNA13 (HGNC)
GNAI1GeneProductGNAI1 (HGNC)
GNAI2GeneProductGNAI2 (HGNC)
GNAI3GeneProductGNAI3 (HGNC)
GNAQGeneProductGNAQ (HGNC)
GNASGeneProductGNAS (HGNC)
GNB1GeneProductGNB1 (HGNC)
GNB2GeneProductGNB2 (HGNC)
GNB3GeneProductGNB3 (HGNC)
GNB4GeneProductGNB4 (HGNC)
GNB5GeneProductGNB5 (HGNC)
GNG10GeneProductGNG10 (HGNC)
GNG11GeneProductGNG11 (HGNC)
GNG12GeneProductGNG12 (HGNC)
GNG13GeneProductGNG13 (HGNC)
GNG2GeneProductGNG2 (HGNC)
GNG3GeneProductGNG3 (HGNC)
GNG4GeneProductGNG4 (HGNC)
GNG5GeneProductENSG00000174021 (Ensembl)
GNG7GeneProductGNG7 (HGNC)
GNG8GeneProductGNG8 (HGNC)
GNGT1GeneProductGNGT1 (HGNC)
GNGT2GeneProductGNGT2 (HGNC)
GRB2GeneProductGRB2 (HGNC)
GSK3BGeneProductGSK3B (HGNC)
GSTA1GeneProductGSTA1 (HGNC)
GSTA2GeneProductGSTA2 (HGNC)
GSTA3GeneProductGSTA3 (HGNC)
GSTA4GeneProductGSTA4 (HGNC)
GSTA5GeneProductGSTA5 (HGNC)
GSTM1GeneProductGSTM1 (HGNC)
GSTM2GeneProductGSTM2 (HGNC)
GSTM3GeneProductGSTM3 (HGNC)
GSTM4GeneProductGSTM4 (HGNC)
GSTM5GeneProductGSTM5 (HGNC)
GSTO1GeneProductGSTO1 (HGNC)
GSTO2GeneProductGSTO2 (HGNC)
GSTP1GeneProductGSTP1 (HGNC)
GSTT1GeneProductGSTT1 (HGNC)
GSTT2BGeneProductGSTT2B (HGNC)
GSTT2GeneProductGSTT2 (HGNC)
HDAC1GeneProductHDAC1 (HGNC)
HDAC2GeneProductHDAC2 (HGNC)
HES1GeneProductHES1 (HGNC)
HES5GeneProductHES5 (HGNC)
HEY1GeneProductHEY1 (HGNC)
HEY2GeneProductHEY2 (HGNC)
HEYLGeneProductHEYL (HGNC)
HGFGeneProductHGF (HGNC)
HHIPGeneProductHHIP (HGNC)
HIF-1 signaling pathwayPathway
HIF1AGeneProductHIF1A (HGNC)
HMOX1GeneProductHMOX1 (HGNC)
HRASGeneProductHRAS (HGNC)
HSP90AA1GeneProductHSP90AA1 (HGNC)
HSP90AB1GeneProductHSP90AB1 (HGNC)
HSP90B1GeneProductHSP90B1 (HGNC)
Hedgehog signaling pathwayPathwayWP4249 (WikiPathways)
Hydrogen peroxideMetaboliteHMDB03125 (HMDB)
Hydroperoxyl radicalMetaboliteC21641 (ChEMBL compound)
Hydroxyl radicalMetaboliteC16844 (KEGG Compound)
IGF1GeneProductIGF1 (HGNC)
IGF1RGeneProductIGF1R (HGNC)
IGF2GeneProductIGF2 (HGNC)
IKBKBGeneProductIKBKB (HGNC)
IKBKGGeneProductIKBKG (HGNC)
IL6GeneProductIL6 (HGNC)
IP3MetaboliteC01245 (KEGG Compound)
ITGA2BGeneProductITGA2B (HGNC)
ITGA2GeneProductITGA2 (HGNC)
ITGA3GeneProductITGA3 (HGNC)
ITGA6GeneProductITGA6 (HGNC)
ITGAVGeneProductITGAV (HGNC)
ITGB1GeneProductITGB1 (HGNC)
JAG1GeneProductJAG1 (HGNC)
JAG2GeneProductJAG2 (HGNC)
JAK1GeneProductJAK1 (HGNC)
JAK2GeneProductJAK2 (HGNC)
JAK3GeneProductJAK3 (HGNC)
JUNGeneProductJUN (HGNC)
JUPGeneProductJUP (HGNC)
Jak-STAT signaling pathwayPathway
KEAP1GeneProductKEAP1 (HGNC)
KIF7GeneProductKIF7 (HGNC)
KITGeneProductKIT (HGNC)
KITLGGeneProductKITLG (HGNC)
KLK3GeneProductKLK3 (HGNC)
KNG1GeneProductKNG1 (HGNC)
KRASGeneProductKRAS (HGNC)
LAMA1GeneProductLAMA1 (HGNC)
LAMA2GeneProductLAMA2 (HGNC)
LAMA3GeneProductLAMA3 (HGNC)
LAMA4GeneProductLAMA4 (HGNC)
LAMA5GeneProductLAMA5 (HGNC)
LAMB1GeneProductLAMB1 (HGNC)
LAMB2GeneProductLAMB2 (HGNC)
LAMB3GeneProductLAMB3 (HGNC)
LAMB4GeneProductLAMB4 (HGNC)
LAMC1GeneProductLAMC1 (HGNC)
LAMC2GeneProductLAMC2 (HGNC)
LAMC3GeneProductLAMC3 (HGNC)
LEF1GeneProductLEF1 (HGNC)
LPAR1GeneProductLPAR1 (HGNC)
LPAR2GeneProductLPAR2 (HGNC)
LPAR3GeneProductLPAR3 (HGNC)
LPAR4GeneProductLPAR4 (HGNC)
LPAR5GeneProductLPAR5 (HGNC)
LPAR6GeneProductLPAR6 (HGNC)
LRP5GeneProductLRP5 (HGNC)
LRP6GeneProductLRP6 (HGNC)
MAP2K1GeneProductMAP2K1 (HGNC)
MAP2K2GeneProductMAP2K2 (HGNC)
MAPK signaling pathwayPathwayWP382 (WikiPathways)
MAPK10GeneProductMAPK10 (HGNC)
MAPK1GeneProductMAPK1 (HGNC)
MAPK3GeneProductMAPK3 (HGNC)
MAPK8GeneProductMAPK8 (HGNC)
MAPK9GeneProductMAPK9 (HGNC)
MAXGeneProductMAX (HGNC)
MDM2GeneProductMDM2 (HGNC)
MECOMGeneProductMECOM (HGNC)
METGeneProductMET (HGNC)
MGST1GeneProductMGST1 (HGNC)
MGST2GeneProductMGST2 (HGNC)
MGST3GeneProductMGST3 (HGNC)
MITFGeneProductMITF (HGNC)
MLH1GeneProductMLH1 (HGNC)
MMP1GeneProductMMP1 (HGNC)
MMP2GeneProductMMP2 (HGNC)
MMP3GeneProductMMP3 (HGNC)
MSH2GeneProductMSH2 (HGNC)
MSH3GeneProductMSH3 (HGNC)
MSH6GeneProductMSH6 (HGNC)
MST1GeneProductMST1 (HGNC)
MTORGeneProductMTOR (HGNC)
MYCGeneProductMYC (HGNC)
MalateMetaboliteCHEBI:30797 (ChEBI)
NCOA1GeneProductNCOA1 (HGNC)
NCOA3GeneProductNCOA3 (HGNC)
NCOA4GeneProductNCOA4 (HGNC)
NFE2L2GeneProductNFE2L2 (HGNC)
NFKB1GeneProductNFKB1 (HGNC)
NFKB2GeneProductNFKB2 (HGNC)
NFKBIAGeneProductNFKBIA (HGNC)
NKX3-1GeneProductNKX3-1 (HGNC)
NOS2GeneProductNOS2 (HGNC)
NOTCH1GeneProductNOTCH1 (HGNC)
NOTCH2GeneProductNOTCH2 (HGNC)
NOTCH3GeneProductNOTCH3 (HGNC)
NOTCH4GeneProductNOTCH4 (HGNC)
NQO1GeneProductNQO1 (HGNC)
NRASGeneProductNRAS (HGNC)
NTRK1GeneProductNTRK1 (HGNC)
Nitric oxideMetaboliteHMDB03378 (HMDB)
Notch signaling pathwayPathwayWP268 (WikiPathways)
PAMetaboliteC00416 (KEGG Compound)
PAX8GeneProductPAX8 (HGNC)
PDGFAGeneProductPDGFA (HGNC)
PDGFBGeneProductPDGFB (HGNC)
PDGFRAGeneProductPDGFRA (HGNC)
PDGFRBGeneProductPDGFRB (HGNC)
PGE2MetaboliteHMDB01220 (HMDB)
PGFGeneProductPGF (HGNC)
PI3K-Akt signaling pathwayPathwayWP4172 (KEGG Pathway)
PIK3CAGeneProductPIK3CA (HGNC)
PIK3CBGeneProductPIK3CB (HGNC)
PIK3CDGeneProductPIK3CD (HGNC)
PIK3R1GeneProductPIK3R1 (HGNC)
PIK3R2GeneProductPIK3R2 (HGNC)
PIK3R3GeneProductPIK3R3 (HGNC)
PIM1GeneProductPIM1 (HGNC)
PIM2GeneProductPIM2 (HGNC)
PIP3MetaboliteC05981 (KEGG Compound)
PLCB1GeneProductPLCB1 (HGNC)
PLCB2GeneProductPLCB2 (HGNC)
PLCB3GeneProductPLCB3 (HGNC)
PLCB4GeneProductPLCB4 (HGNC)
PLCG1GeneProductPLCG1 (HGNC)
PLCG2GeneProductPLCG2 (HGNC)
PLD1GeneProductPLD1 (HGNC)
PLD2GeneProductPLD2 (HGNC)
PLEKHG5GeneProductPLEKHG5 (HGNC)
PMAIP1GeneProductPMAIP1 (HGNC)
PMLGeneProductPML (HGNC)
POLKGeneProductPOLK (HGNC)
PPAR signaling pathwayPathwayWP3942 (WikiPathways)
PPARDGeneProductPPARD (HGNC)
PPARGGeneProductPPARG (HGNC)
PRKACAGeneProductPRKACA (HGNC)
PRKACBGeneProductPRKACB (HGNC)
PRKACGGeneProductPRKACG (HGNC)
PRKCAGeneProductPRKCA (HGNC)
PRKCBGeneProductPRKCB (HGNC)
PRKCGGeneProductPRKCG (HGNC)
PTCH1GeneProductPTCH1 (HGNC)
PTCH2GeneProductPTCH2 (HGNC)
PTENGeneProductPTEN (HGNC)
PTGER1GeneProductPTGER1 (HGNC)
PTGER2GeneProductPTGER2 (HGNC)
PTGER3GeneProductPTGER3 (HGNC)
PTGER4GeneProductPTGER4 (HGNC)
PTGS2GeneProductPTGS2 (HGNC)
PTK2GeneProductPTK2 (HGNC)
ProgesteroneMetaboliteHMDB01830 (HMDB)
RAC1GeneProductRAC1 (HGNC)
RAC2GeneProduct5880 (Entrez Gene)
RAC3GeneProductRAC3 (HGNC)
RAD51GeneProductRAD51 (HGNC)
RAF1GeneProductRAF1 (HGNC)
RALAGeneProductRALA (HGNC)
RALBP1GeneProductRALBP1 (HGNC)
RALBGeneProductRALB (HGNC)
RALGDSGeneProductRALGDS (HGNC)
RARAGeneProductRARA (HGNC)
RARBGeneProductRARB (HGNC)
RASGRP1GeneProductRASGRP1 (HGNC)
RASGRP2GeneProductRASGRP2 (HGNC)
RASGRP3GeneProductRASGRP3 (HGNC)
RASGRP4GeneProductRASGRP4 (HGNC)
RASSF1GeneProductRASSF1 (HGNC)
RASSF5GeneProductRASSF5 (HGNC)
RB1GeneProductRB1 (HGNC)
RBX1GeneProductRBX1 (HGNC)
RELAGeneProductRELA (HGNC)
RETGeneProductRET (HGNC)
RHOAGeneProductRHOA (HGNC)
ROCK1GeneProductROCK1 (HGNC)
ROCK2GeneProductROCK2 (HGNC)
RPS6KA5GeneProductRPS6KA5 (HGNC)
RPS6KB1GeneProductRPS6KB1 (HGNC)
RPS6KB2GeneProductRPS6KB2 (HGNC)
RUNX1GeneProductRUNX1 (HGNC)
RUNX1T1GeneProductRUNX1T1 (HGNC)
RXRAGeneProductRXRA (HGNC)
RXRBGeneProductRXRB (HGNC)
RXRGGeneProductRXRG (HGNC)
Retinoic AcidMetaboliteCHEBI:15367 (ChEBI)
SHHGeneProductSHH (HGNC)
SKP1GeneProductSKP1 (HGNC)
SKP2GeneProductSKP2 (HGNC)
SLC2A1GeneProductSLC2A1 (HGNC)
SMAD2GeneProductSMAD2 (HGNC)
SMAD3GeneProductSMAD3 (HGNC)
SMAD4GeneProductSMAD4 (HGNC)
SMOGeneProductSMO (HGNC)
SOS1GeneProductSOS1 (HGNC)
SOS2GeneProductSOS2 (HGNC)
SP1GeneProductENSG00000185591 (Ensembl)
SPI1GeneProductSPI1 (HGNC)
STAT1GeneProductSTAT1 (HGNC)
STAT2GeneProductSTAT2 (HGNC)
STAT3GeneProductSTAT3 (HGNC)
STAT4GeneProductSTAT4 (HGNC)
STAT5AGeneProductSTAT5A (HGNC)
STAT5BGeneProductSTAT5B (HGNC)
STAT6GeneProductSTAT6 (HGNC)
SUFUGeneProductSUFU (HGNC)
SuperoxideMetaboliteHMDB02168 (HMDB)
TCF7L1GeneProductTCF7L1 (HGNC)
TCF7L2GeneProductTCF7L2 (HGNC)
TCF7GeneProductTCF7 (HGNC)
TERCGeneProductTERC (HGNC)
TERTGeneProductTERT (HGNC)
TFGGeneProductTFG (HGNC)
TGF-beta signaling pathwayPathwayWP560 (WikiPathways)
TGFAGeneProductTGFA (HGNC)
TGFB1GeneProductTGFB1 (HGNC)
TGFB2GeneProductTGFB2 (HGNC)
TGFB3GeneProductTGFB3 (HGNC)
TGFBR1GeneProductTGFBR1 (HGNC)
TGFBR2GeneProductTGFBR2 (HGNC)
TP53GeneProductTP53 (HGNC)
TPM3GeneProductTPM3 (HGNC)
TPRGeneProductTPR (HGNC)
TRAF1GeneProductTRAF1 (HGNC)
TRAF2GeneProductTRAF2 (HGNC)
TRAF3GeneProductTRAF3 (HGNC)
TRAF4GeneProductTRAF4 (HGNC)
TRAF5GeneProductTRAF5 (HGNC)
TRAF6GeneProductTRAF6 (HGNC)
TXNRD1GeneProductTXNRD1 (HGNC)
TXNRD2GeneProductTXNRD2 (HGNC)
TXNRD3GeneProductTXNRD3 (HGNC)
TestosteroneMetaboliteHMDB00234 (HMDB)
VEGF signaling pathwayPathwayWP3888 (WikiPathways)
VEGFAGeneProductVEGFA (HGNC)
VEGFBGeneProductVEGFB (HGNC)
VEGFCGeneProductVEGFC (HGNC)
VEGFDGeneProductVEGFD (HGNC)
VHLGeneProductVHL (HGNC)
WNT10AGeneProductWNT10A (HGNC)
WNT10BGeneProductWNT10B (HGNC)
WNT11GeneProductWNT11 (HGNC)
WNT16GeneProductWNT16 (HGNC)
WNT1GeneProductWNT1 (HGNC)
WNT2BGeneProductWNT2B (HGNC)
WNT2GeneProductWNT2 (HGNC)
WNT3AGeneProductWNT3A (HGNC)
WNT3GeneProductWNT3 (HGNC)
WNT4GeneProductWNT4 (HGNC)
WNT5AGeneProductWNT5A (HGNC)
WNT5BGeneProductWNT5B (HGNC)
WNT6GeneProductWNT6 (HGNC)
WNT7AGeneProductWNT7A (HGNC)
WNT7BGeneProductWNT7B (HGNC)
WNT8AGeneProductWNT8A (HGNC)
WNT8BGeneProductWNT8B (HGNC)
WNT9AGeneProductWNT9A (HGNC)
WNT9BGeneProductWNT9B (HGNC)
Wnt signaling pathwayPathwayWP428 (WikiPathways)
XIAPGeneProductXIAP (HGNC)
ZBTB16GeneProductZBTB16 (HGNC)
ZBTB17GeneProductZBTB17 (HGNC)
cAMP signaling pathwayPathway
cAMPMetaboliteCHEBI:17489 (ChEBI)
fumarateMetaboliteCHEBI:29806 (ChEBI)
mTOR signaling pathwayPathwayWP3932 (WikiPathways)
p53 signaling pathwayPathway

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5434"
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