Cancer pathways (Homo sapiens)

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Revision as of 00:06, 30 January 2024 by Khanspers (Talk | contribs)
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MitochondriaMicrotubulePU.1 target genesTelomeric DNA repeatsCarcinogensSustainedangiogenesisLigandsRARatarget genesDNA damage?Oxidative or electrophilic stressInterraction interrupted by mutation etcNotch signaling pathwayTGFACa2+IGF1RSOS1CDKN1BTP53TGFBR2ARCalcium signalingpathwayFGF1RAC1KNG1METIP3SMAD2TRAF1GNAI1Estrogen signalingpathwayEDNRALRP5PTCH1CREBBPNFE2L2HRASAPPL1PLCB1DNANKX3-1CDK2GNB5ARNTSKP2CASP3DCCPLD1TXNRD1MTORCASP3EDN1CEBPAFocal adhesionMDM2Hydroperoxyl radicalSMAD4MAPK1PTCH1DAGCCND1ProgesteroneCDKN2BHEY1EstradiolGNA13CTNNB1BAK1CUL2RASSF1RPS6KB1CDKN2ARHOACSF2RASTAT1RASGRP1FLT3LGELOBPOLKAPAF1FADDCell cyclePLCG1RUNX1TFGAcroleinCDKN1BPTENCASP9PPARDCHUKPMLSHHAGTPMAIP1GLI1MSH3CCND1BMP2MLH1CTBP1Adherens junctionMYCHHIPMAP2K1ABL1CASP9GRB2MSH2VEGF signalingpathwayKEAP1JAK1GNA11ITGB1MMP1APC2SPI1CDKN2AERBB2SuperoxideMAPK signalingpathwayCRKSUFUCSF3RPRKACAEGLN2Hydrogen peroxideCXCL8CXCR4FRAT1RB1MYCNitric oxideGSTP1PPAR signalingpathwayIL6SKP1TGFBR1MITFKITLGCAMK2APRKCAKLK3HDAC1PGFZBTB17fumaratemTOR signalingpathwayTGFARUNX1RALABCL2HSP90AA1ApoptosisGSK3BHydroxyl radicalTGFB1cAMP signalingpathwayRHOAMSH6SMOITGA6RASSF1JUNBCL2L1DDB2PIM2DVL1PTK2PDGFRABAXCXCL12PI3K-Aktsignaling pathwayEGFFOXO1CDKN1AMECOMTERTAXIN1STAT5AESR1MYCJak-STAT signaling pathwaycAMPFASLGJUPADCY1TERCVEGFDCSF1RCCNE1RETELOCFHCholesterolCDKN1ACCNA2CCND1JAG1TGFBR2BAK1ALKHGFp53 signalingpathwayHIF-1 signalingpathwayBCL2L1KIF7NOTCH1FGFR1CKS1BDLL3LEF1NQO1BIRC5BIRC2NCOA3BCL2L11SPI1ETS1ARAFRALGDSMAXEGFRTP53PDGFAF2TGFB1RBX1GNASCDK4PGE2E2F1HES1FLT4PIP3IGF1STAT2SLC2A1NOS2PTGS2NFKBIABCL2BRCA2CTNNA1RARADehydroepiandrosteroneRAD51ROCK1GADD45GPIK3CAFOSBADCDH1Wnt signalingpathwayNFKB1RASSF5FASTestosteroneARHGEF12RALBP1CTNNB1CDK4HMOX1MAPK8EPAS1Hedgehog signaling pathwayFLT3KITELK1WNT16RXRACASP3PACALML1CTNNB1MYCCYCSRPS6KA5DAPK1MDM2STAT3RARBPPARGCASP8Retinoic AcidBBC3PTGER1TGF-beta signalingpathwayVHLPDGFBBADBAXEstradiolLPAR6IP3BIDPPPPPPPPPPPPPPPJAG2PPPPPPDLL4DLL1GLI2GLI3DihydrotestosteroneFlutamideAndrostenedioneCortisolCortisoneARHSP90AB1HSP90B1ARNOTCH2NOTCH3NOTCH4BMP4GLI1PTCH2HES5HEY2HEYLEGLN1EGLN3MalateHIF1AARNT2EP300VEGFAVEGFBVEGFCTGFB2TGFB34-HNETXNRD2TXNRD3CASP7Evaiding apoptosisMitochondriaTGFB2TGFB3SMAD3Genomic damageInsesitivity toanti-growth signalsResistance tochemotherapyImmortalityHDAC2CTBP2DNAGenomic instabilityGADD45BGADD45ACDK6CCND2CCND3E2F2E2F3ProliferationCCNE2RBX1CUL1CKS1BBlock ofdifferentiationE2F1E2F2E2F3CSF1RCSF1RC/EBPa target genesAML1 target genesRARAZBTB16RUNX1RUNX1T1CCNA1CCND1TCF7TCF7L2TCF7L1SP1ESR2NCOA1ESR1ESR2EstradiolEstradiolRXRBRXRGRXRARXRBRXRGPPARGPAX8CCND1VEGFDVEGFAVEGFBVEGFCMMP2MMP3FOSPMYCPJUNPMAPK3PDAPK2DAPK3MAP2K2PBRAFRAF1NRASKRASSOS2ERBB2PDGFRBFGFR2FGFR3FGFR4IGF2PDGFBRALBPLD2RAC2RAC3MAPK9MAPK10RAC1RAC2RAC3CCDC42PLCG2EML4PPRKCBPRKCGCCDC6NCOA4NTRK1TPM3TPRTissue invasion and metastasisCTNNA3CTNNA2AXIN2APCFRAT2DVL2DVL3MYCCCND1LEF1TCF7TCF7L2TCF7L1PGFVEGFDVEGFAVEGFBVEGFCLRP6PTGER2PTGER3PTGER4AGTR1LPAR1F2RLPAR2LPAR3LPAR4LPAR5F2RL3GNA12ARHGEF11ARHGEF1PLEKHG5ROCK2GNAI2GNAI3ADCY2ADCY3ADCY4ADCY5ADCY6ADCY7ADCY8ADCY9PRKACBPRKACGGNB1GNB2GNB3GNG3GNG4GNG5GNG7GNG10GNG11GNGT1BCL2L1PIM1BIRC3BIRC7XIAPTRAF2TRAF3TRAF4TRAF5TRAF6GNGT2GNG13GNG2GNG12GNG8GNB4ITGA2ITGA2BITGA3ITGAVEDNRBF2AGTBDKRB1BDKRB2GNAQPLCB2PLCB3PLCB4PRKCAPRKCBPRKCGCa2+DAGJAK2JAK3RASGRP2RASGRP3RASGRP4ALKEML4MST1STAT5BSTAT4PSTAT6BCRCBLPCRKLPPIK3CBPIK3CDPIK3R1PIK3R2PIK3R3AKT1AKT2AKT3IKBKBIKBKGPPNFKB2RELACASP9PBCL2L1RPS6KB2PCALML2CALML3CALML4CALML5CALML6CAMK2BCAMK2DCAMK2GWNT4WNT1WNT2WNT3WNT5AWNT6WNT7AWNT7BWNT8AWNT8BWNT10BWNT11WNT2BWNT9AWNT9BWNT10AWNT5BWNT3AFZD10FZD2FZD5FZD3FZD1FZD4FZD6FZD7FZD8FZD9LAMC3COL4A1COL4A2COL4A3COL4A4COL4A5COL4A6LAMB4FN1LAMA1LAMA2LAMA3LAMA4LAMA5LAMB1LAMB2LAMB3LAMC1LAMC2GSTO2GSTA5GSTA1GSTA2GSTA3GSTA4GSTM1GSTM2GSTM3GSTM4GSTM5GSTP1GSTT1GSTT2MGST1MGST2MGST3GSTT2BGSTO1GLI1GLI2GLI3WNT16WNT4WNT1WNT2WNT3WNT5AWNT6WNT7AWNT7BWNT8AWNT8BWNT10BWNT11WNT2BWNT9AWNT9BWNT10AWNT5BWNT3AEPOIFNA1IFNA2IFNA4IFNA5IFNA6IFNA7IFNA8IFNA10IFNA13IFNA14IFNA16IFNA17IFNA21IFNGIL2IL3IL4IL5IL6IL7IL12AIL12BIL13IL15IL23AIL23ACSF2RBIL23AEPORIFNAR1IFNAR2IFNGR1IFNGR2IL2RAIL2RBIL2RGIL3RAIL4RIL5RAIL6RIL6STIL7RIL12RB1IL12RB2IL13RA1IL15RAIL15RALegend


Description

draft pathway describing pathways in cancer

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View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. ''Pathways in cancer''; https://www.kegg.jp/dbget-bin/www_bget?pathway+hsa05200,

History

View all...
CompareRevisionActionTimeUserComment
135326view19:19, 21 August 2024Khanspersupdated kegg reference
135315view21:04, 19 August 2024Khanspersupdate KEGG ref
129459view01:04, 23 April 2024EweitzModified title
129136view16:45, 12 March 2024Khanspersminor tweak to test
128705view22:04, 20 February 2024EgonwMade a few pathways clickable
128257view00:14, 30 January 2024KhanspersModified description
128256view00:11, 30 January 2024Khanspersupdated lit ref
128254view00:08, 30 January 2024KhanspersOntology Term : 'cancer' added !
128253view00:08, 30 January 2024KhanspersOntology Term : 'altered signaling pathway' added !
128252view00:06, 30 January 2024Khanspersadded cell shape, legend, phospho sites
127898view00:17, 10 January 2024Khanspersnode sizing and layout
127897view00:08, 10 January 2024Khanspersadded cytokines and cytokine receptors
127896view22:57, 9 January 2024Khansperslayout
127895view22:51, 9 January 2024Khanspersadded wnts
127872view22:50, 3 January 2024Khansperslayout
127871view19:59, 3 January 2024Khansperscomplexes and interactions
127866view23:51, 2 January 2024Khanspersinteractions
127865view23:38, 2 January 2024Khanspersupdated interactions etc
127864view22:58, 2 January 2024Khansperslayout and interactions
127863view22:51, 2 January 2024Khanspersadded gst
127861view22:41, 2 January 2024Khanspersadded ecm
127859view22:33, 2 January 2024Khanspersadded wnt, fzd
127827view21:26, 21 December 2023KhanspersOntology Term : 'cancer pathway' added !
127826view21:25, 21 December 2023KhanspersModified title
127825view21:24, 21 December 2023KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
4-HNEMetaboliteC21642 (KEGG Compound)
ABL1GeneProductABL1 (HGNC)
ADCY1GeneProductADCY1 (HGNC)
ADCY2GeneProductADCY2 (HGNC)
ADCY3GeneProductADCY3 (HGNC)
ADCY4GeneProductADCY4 (HGNC)
ADCY5GeneProductADCY5 (HGNC)
ADCY6GeneProductADCY6 (HGNC)
ADCY7GeneProductADCY7 (HGNC)
ADCY8GeneProductADCY8 (HGNC)
ADCY9GeneProductADCY9 (HGNC)
AGTGeneProductAGT (HGNC)
AGTR1GeneProductAGTR1 (HGNC)
AKT1GeneProductAKT1 (HGNC)
AKT2GeneProductAKT2 (HGNC)
AKT3GeneProductAKT3 (HGNC)
ALKGeneProductALK (HGNC)
APAF1GeneProductAPAF1 (HGNC)
APC2GeneProductAPC2 (HGNC)
APCGeneProductAPC (HGNC)
APPL1GeneProductAPPL1 (HGNC)
ARAFGeneProductARAF (HGNC)
ARGeneProductAR (HGNC)
ARHGEF11GeneProductARHGEF11 (HGNC)
ARHGEF12GeneProductARHGEF12 (HGNC)
ARHGEF1GeneProductARHGEF1 (HGNC)
ARNT2GeneProductARNT2 (HGNC)
ARNTGeneProductARNT (HGNC)
AXIN1GeneProductAXIN1 (HGNC)
AXIN2GeneProductAXIN2 (HGNC)
AcroleinMetaboliteC01471 (KEGG Compound)
Adherens junctionPathway
AndrostenedioneMetaboliteHMDB00053 (HMDB)
ApoptosisPathwayWP254 (WikiPathways)
BADGeneProductBAD (HGNC)
BAK1GeneProductBAK1 (HGNC)
BAXGeneProductBAX (HGNC)
BBC3GeneProductBBC3 (HGNC)
BCL2GeneProductBCL2 (HGNC)
BCL2L11GeneProductBCL2L11 (HGNC)
BCL2L1GeneProductBCL2L1 (HGNC)
BCRGeneProductBCR (HGNC)
BDKRB1GeneProductBDKRB1 (HGNC)
BDKRB2GeneProductBDKRB2 (HGNC)
BIDGeneProductBID (HGNC)
BIRC2GeneProductBIRC2 (HGNC)
BIRC3GeneProductBIRC3 (HGNC)
BIRC5GeneProductBIRC5 (HGNC)
BIRC7GeneProductBIRC7 (HGNC)
BMP2GeneProductBMP2 (HGNC)
BMP4GeneProductBMP4 (HGNC)
BRAFGeneProductBRAF (HGNC)
BRCA2GeneProductBRCA2 (HGNC)
CALML1GeneProductCALML1 (HGNC)
CALML2GeneProductCALML2 (HGNC)
CALML3GeneProductCALML3 (HGNC)
CALML4GeneProductCALML4 (HGNC)
CALML5GeneProductCALML5 (HGNC)
CALML6GeneProductCALML6 (HGNC)
CAMK2AGeneProductCAMK2A (HGNC)
CAMK2BGeneProductCAMK2B (HGNC)
CAMK2DGeneProductCAMK2D (HGNC)
CAMK2GGeneProductCAMK2G (HGNC)
CASP3GeneProductCASP3 (HGNC)
CASP7GeneProductCASP7 (HGNC)
CASP8GeneProductCASP8 (HGNC)
CASP9GeneProductCASP9 (HGNC)
CBLGeneProductCBL (HGNC)
CCDC42GeneProductCCDC42 (HGNC)
CCDC6GeneProductCCDC6 (HGNC)
CCNA1GeneProductCCNA1 (HGNC)
CCNA2GeneProductCCNA2 (HGNC)
CCND1GeneProductCCND1 (HGNC)
CCND2GeneProductCCND2 (HGNC)
CCND3GeneProductCCND3 (HGNC)
CCNE1GeneProductCCNE1 (HGNC)
CCNE2GeneProductCCNE2 (HGNC)
CDH1GeneProductCDH1 (HGNC)
CDK2GeneProductCDK2 (HGNC)
CDK4GeneProductCDK4 (HGNC)
CDK6GeneProductCDK6 (HGNC)
CDKN1AGeneProductCDKN1A (HGNC)
CDKN1BGeneProductCDKN1B (HGNC)
CDKN2AGeneProductCDKN2A (HGNC)
CDKN2BGeneProductCDKN2B (HGNC)
CEBPAGeneProductCEBPA (HGNC)
CHUKGeneProductCHUK (HGNC)
CKS1BGeneProductCKS1B (HGNC)
COL4A1GeneProductCOL4A1 (HGNC)
COL4A2GeneProductCOL4A2 (HGNC)
COL4A3GeneProductCOL4A3 (HGNC)
COL4A4GeneProductCOL4A4 (HGNC)
COL4A5GeneProductCOL4A5 (HGNC)
COL4A6GeneProductCOL4A6 (HGNC)
CREBBPGeneProductCREBBP (HGNC)
CRKGeneProductCRK (HGNC)
CRKLGeneProductCRKL (HGNC)
CSF1RGeneProductCSF1R (HGNC)
CSF2RAGeneProductCSF2RA (HGNC)
CSF2RBGeneProductCSF2RB (HGNC)
CSF3RGeneProductCSF3R (HGNC)
CTBP1GeneProductCTBP1 (HGNC)
CTBP2GeneProductCTBP2 (HGNC)
CTNNA1GeneProductCTNNA1 (HGNC)
CTNNA2GeneProductCTNNA2 (HGNC)
CTNNA3GeneProductCTNNA3 (HGNC)
CTNNB1GeneProductCTNNB1 (HGNC)
CUL1GeneProductCUL1 (HGNC)
CUL2GeneProductCUL2 (HGNC)
CXCL12GeneProductCXCL12 (HGNC)
CXCL8GeneProductCXCL8 (HGNC)
CXCR4GeneProductCXCR4 (HGNC)
CYCSGeneProductCYCS (HGNC)
Ca2+MetaboliteCHEBI:29108 (ChEBI)
Calcium signaling pathwayPathway
Cell cyclePathwayWP179 (WikiPathways)
CholesterolMetaboliteHMDB00067 (HMDB)
CortisolMetaboliteHMDB00063 (HMDB)
CortisoneMetaboliteHMDB02802 (HMDB)
DAGMetaboliteC00165 (KEGG Compound)
DAPK1GeneProductDAPK1 (HGNC)
DAPK2GeneProductDAPK2 (HGNC)
DAPK3GeneProductDAPK3 (HGNC)
DCCGeneProductDCC (HGNC)
DDB2GeneProductDDB2 (HGNC)
DLL1GeneProductDLL1 (HGNC)
DLL3GeneProductDLL3 (HGNC)
DLL4GeneProductDLL4 (HGNC)
DNAMetaboliteCHEBI:16991 (ChEBI)
DVL1GeneProductDVL1 (HGNC)
DVL2GeneProductDVL2 (HGNC)
DVL3GeneProductDVL3 (HGNC)
DehydroepiandrosteroneMetaboliteHMDB00077 (HMDB)
DihydrotestosteroneMetaboliteHMDB02961 (HMDB)
E2F1GeneProductE2F1 (HGNC)
E2F2GeneProductE2F2 (HGNC)
E2F3GeneProductE2F3 (HGNC)
EDN1GeneProductEDN1 (HGNC)
EDNRAGeneProductEDNRA (HGNC)
EDNRBGeneProductEDNRB (HGNC)
EGFGeneProductEGF (HGNC)
EGFRGeneProductEGFR (HGNC)
EGLN1GeneProductEGLN1 (HGNC)
EGLN2GeneProductEGLN2 (HGNC)
EGLN3GeneProductEGLN3 (HGNC)
ELK1GeneProductELK1 (HGNC)
ELOBGeneProductELOB (HGNC)
ELOCGeneProductELOC (HGNC)
EML4GeneProductEML4 (HGNC)
EP300GeneProductEP300 (HGNC)
EPAS1GeneProductEPAS1 (HGNC)
EPOGeneProductEPO (HGNC)
EPORGeneProductEPOR (HGNC)
ERBB2GeneProductERBB2 (HGNC)
ESR1GeneProductESR1 (HGNC)
ESR2GeneProductESR2 (HGNC)
ETS1GeneProductETS1 (HGNC)
EstradiolMetaboliteHMDB00151 (HMDB)
Estrogen signaling pathwayPathwayWP712 (WikiPathways)
F2GeneProductF2 (HGNC)
F2RGeneProductF2R (HGNC)
F2RL3GeneProductF2RL3 (HGNC)
FADDGeneProductFADD (HGNC)
FASGeneProductFAS (HGNC)
FASLGGeneProductFASLG (HGNC)
FGF1GeneProductFGF1 (HGNC)
FGFR1GeneProductFGFR1 (HGNC)
FGFR2GeneProductFGFR2 (HGNC)
FGFR3GeneProductFGFR3 (HGNC)
FGFR4GeneProductFGFR4 (HGNC)
FHGeneProductFH (HGNC)
FLT3GeneProductFLT3 (HGNC)
FLT3LGGeneProductFLT3LG (HGNC)
FLT4GeneProductFLT4 (HGNC)
FN1GeneProductFN1 (HGNC)
FOSGeneProductFOS (HGNC)
FOXO1GeneProductFOXO1 (HGNC)
FRAT1GeneProductFRAT1 (HGNC)
FRAT2GeneProductFRAT2 (HGNC)
FZD10GeneProductFZD10 (HGNC)
FZD1GeneProductFZD1 (HGNC)
FZD2GeneProductFZD2 (HGNC)
FZD3GeneProductFZD3 (HGNC)
FZD4GeneProductFZD4 (HGNC)
FZD5GeneProductFZD5 (HGNC)
FZD6GeneProductFZD6 (HGNC)
FZD7GeneProductFZD7 (HGNC)
FZD8GeneProductFZD8 (HGNC)
FZD9GeneProductFZD9 (HGNC)
FlutamideMetaboliteHMDB14642 (HMDB)
Focal adhesionPathwayWP306 (WikiPathways)
GADD45AGeneProductGADD45A (HGNC)
GADD45BGeneProductGADD45B (HGNC)
GADD45GGeneProductGADD45G (HGNC)
GLI1GeneProductGLI1 (HGNC)
GLI2GeneProductGLI2 (HGNC)
GLI3GeneProductGLI3 (HGNC)
GNA11GeneProductGNA11 (HGNC)
GNA12GeneProductGNA12 (HGNC)
GNA13GeneProductGNA13 (HGNC)
GNAI1GeneProductGNAI1 (HGNC)
GNAI2GeneProductGNAI2 (HGNC)
GNAI3GeneProductGNAI3 (HGNC)
GNAQGeneProductGNAQ (HGNC)
GNASGeneProductGNAS (HGNC)
GNB1GeneProductGNB1 (HGNC)
GNB2GeneProductGNB2 (HGNC)
GNB3GeneProductGNB3 (HGNC)
GNB4GeneProductGNB4 (HGNC)
GNB5GeneProductGNB5 (HGNC)
GNG10GeneProductGNG10 (HGNC)
GNG11GeneProductGNG11 (HGNC)
GNG12GeneProductGNG12 (HGNC)
GNG13GeneProductGNG13 (HGNC)
GNG2GeneProductGNG2 (HGNC)
GNG3GeneProductGNG3 (HGNC)
GNG4GeneProductGNG4 (HGNC)
GNG5GeneProductENSG00000174021 (Ensembl)
GNG7GeneProductGNG7 (HGNC)
GNG8GeneProductGNG8 (HGNC)
GNGT1GeneProductGNGT1 (HGNC)
GNGT2GeneProductGNGT2 (HGNC)
GRB2GeneProductGRB2 (HGNC)
GSK3BGeneProductGSK3B (HGNC)
GSTA1GeneProductGSTA1 (HGNC)
GSTA2GeneProductGSTA2 (HGNC)
GSTA3GeneProductGSTA3 (HGNC)
GSTA4GeneProductGSTA4 (HGNC)
GSTA5GeneProductGSTA5 (HGNC)
GSTM1GeneProductGSTM1 (HGNC)
GSTM2GeneProductGSTM2 (HGNC)
GSTM3GeneProductGSTM3 (HGNC)
GSTM4GeneProductGSTM4 (HGNC)
GSTM5GeneProductGSTM5 (HGNC)
GSTO1GeneProductGSTO1 (HGNC)
GSTO2GeneProductGSTO2 (HGNC)
GSTP1GeneProductGSTP1 (HGNC)
GSTT1GeneProductGSTT1 (HGNC)
GSTT2BGeneProductGSTT2B (HGNC)
GSTT2GeneProductGSTT2 (HGNC)
HDAC1GeneProductHDAC1 (HGNC)
HDAC2GeneProductHDAC2 (HGNC)
HES1GeneProductHES1 (HGNC)
HES5GeneProductHES5 (HGNC)
HEY1GeneProductHEY1 (HGNC)
HEY2GeneProductHEY2 (HGNC)
HEYLGeneProductHEYL (HGNC)
HGFGeneProductHGF (HGNC)
HHIPGeneProductHHIP (HGNC)
HIF-1 signaling pathwayPathway
HIF1AGeneProductHIF1A (HGNC)
HMOX1GeneProductHMOX1 (HGNC)
HRASGeneProductHRAS (HGNC)
HSP90AA1GeneProductHSP90AA1 (HGNC)
HSP90AB1GeneProductHSP90AB1 (HGNC)
HSP90B1GeneProductHSP90B1 (HGNC)
Hedgehog signaling pathwayPathwayWP4249 (WikiPathways)
Hydrogen peroxideMetaboliteHMDB03125 (HMDB)
Hydroperoxyl radicalMetaboliteC21641 (ChEMBL compound)
Hydroxyl radicalMetaboliteC16844 (KEGG Compound)
IFNA10GeneProductIFNA10 (HGNC)
IFNA13GeneProductIFNA13 (HGNC)
IFNA14GeneProductIFNA14 (HGNC)
IFNA16GeneProductIFNA16 (HGNC)
IFNA17GeneProductIFNA17 (HGNC)
IFNA1GeneProductIFNA1 (HGNC)
IFNA21GeneProductIFNA21 (HGNC)
IFNA2GeneProductIFNA2 (HGNC)
IFNA4GeneProductIFNA4 (HGNC)
IFNA5GeneProductIFNA5 (HGNC)
IFNA6GeneProductIFNA6 (HGNC)
IFNA7GeneProductIFNA7 (HGNC)
IFNA8GeneProductIFNA8 (HGNC)
IFNAR1GeneProductIFNAR1 (HGNC)
IFNAR2GeneProductIFNAR2 (HGNC)
IFNGGeneProductIFNG (HGNC)
IFNGR1GeneProductIFNGR1 (HGNC)
IFNGR2GeneProductIFNGR2 (HGNC)
IGF1GeneProductIGF1 (HGNC)
IGF1RGeneProductIGF1R (HGNC)
IGF2GeneProductIGF2 (HGNC)
IKBKBGeneProductIKBKB (HGNC)
IKBKGGeneProductIKBKG (HGNC)
IL12AGeneProductIL12A (HGNC)
IL12BGeneProductIL12B (HGNC)
IL12RB1GeneProductIL12RB1 (HGNC)
IL12RB2GeneProductIL12RB2 (HGNC)
IL13GeneProductIL13 (HGNC)
IL13RA1GeneProductIL13RA1 (HGNC)
IL15GeneProductIL15 (HGNC)
IL15RAGeneProductIL15RA (HGNC)
IL23AGeneProductIL23A (HGNC)
IL2GeneProductIL2 (HGNC)
IL2RAGeneProductIL2RA (HGNC)
IL2RBGeneProductIL2RB (HGNC)
IL2RGGeneProductIL2RG (HGNC)
IL3GeneProductIL3 (HGNC)
IL3RAGeneProductIL3RA (HGNC)
IL4GeneProductIL4 (HGNC)
IL4RGeneProductIL4R (HGNC)
IL5GeneProductIL5 (HGNC)
IL5RAGeneProductIL5RA (HGNC)
IL6GeneProductIL6 (HGNC)
IL6RGeneProductIL6R (HGNC)
IL6STGeneProductIL6ST (HGNC)
IL7GeneProductIL7 (HGNC)
IL7RGeneProductIL7R (HGNC)
IP3MetaboliteC01245 (KEGG Compound)
ITGA2BGeneProductITGA2B (HGNC)
ITGA2GeneProductITGA2 (HGNC)
ITGA3GeneProductITGA3 (HGNC)
ITGA6GeneProductITGA6 (HGNC)
ITGAVGeneProductITGAV (HGNC)
ITGB1GeneProductITGB1 (HGNC)
JAG1GeneProductJAG1 (HGNC)
JAG2GeneProductJAG2 (HGNC)
JAK1GeneProductJAK1 (HGNC)
JAK2GeneProductJAK2 (HGNC)
JAK3GeneProductJAK3 (HGNC)
JUNGeneProductJUN (HGNC)
JUPGeneProductJUP (HGNC)
Jak-STAT signaling pathwayPathway
KEAP1GeneProductKEAP1 (HGNC)
KIF7GeneProductKIF7 (HGNC)
KITGeneProductKIT (HGNC)
KITLGGeneProductKITLG (HGNC)
KLK3GeneProductKLK3 (HGNC)
KNG1GeneProductKNG1 (HGNC)
KRASGeneProductKRAS (HGNC)
LAMA1GeneProductLAMA1 (HGNC)
LAMA2GeneProductLAMA2 (HGNC)
LAMA3GeneProductLAMA3 (HGNC)
LAMA4GeneProductLAMA4 (HGNC)
LAMA5GeneProductLAMA5 (HGNC)
LAMB1GeneProductLAMB1 (HGNC)
LAMB2GeneProductLAMB2 (HGNC)
LAMB3GeneProductLAMB3 (HGNC)
LAMB4GeneProductLAMB4 (HGNC)
LAMC1GeneProductLAMC1 (HGNC)
LAMC2GeneProductLAMC2 (HGNC)
LAMC3GeneProductLAMC3 (HGNC)
LEF1GeneProductLEF1 (HGNC)
LPAR1GeneProductLPAR1 (HGNC)
LPAR2GeneProductLPAR2 (HGNC)
LPAR3GeneProductLPAR3 (HGNC)
LPAR4GeneProductLPAR4 (HGNC)
LPAR5GeneProductLPAR5 (HGNC)
LPAR6GeneProductLPAR6 (HGNC)
LRP5GeneProductLRP5 (HGNC)
LRP6GeneProductLRP6 (HGNC)
MAP2K1GeneProductMAP2K1 (HGNC)
MAP2K2GeneProductMAP2K2 (HGNC)
MAPK signaling pathwayPathwayWP382 (WikiPathways)
MAPK10GeneProductMAPK10 (HGNC)
MAPK1GeneProductMAPK1 (HGNC)
MAPK3GeneProductMAPK3 (HGNC)
MAPK8GeneProductMAPK8 (HGNC)
MAPK9GeneProductMAPK9 (HGNC)
MAXGeneProductMAX (HGNC)
MDM2GeneProductMDM2 (HGNC)
MECOMGeneProductMECOM (HGNC)
METGeneProductMET (HGNC)
MGST1GeneProductMGST1 (HGNC)
MGST2GeneProductMGST2 (HGNC)
MGST3GeneProductMGST3 (HGNC)
MITFGeneProductMITF (HGNC)
MLH1GeneProductMLH1 (HGNC)
MMP1GeneProductMMP1 (HGNC)
MMP2GeneProductMMP2 (HGNC)
MMP3GeneProductMMP3 (HGNC)
MSH2GeneProductMSH2 (HGNC)
MSH3GeneProductMSH3 (HGNC)
MSH6GeneProductMSH6 (HGNC)
MST1GeneProductMST1 (HGNC)
MTORGeneProductMTOR (HGNC)
MYCGeneProductMYC (HGNC)
MalateMetaboliteCHEBI:30797 (ChEBI)
NCOA1GeneProductNCOA1 (HGNC)
NCOA3GeneProductNCOA3 (HGNC)
NCOA4GeneProductNCOA4 (HGNC)
NFE2L2GeneProductNFE2L2 (HGNC)
NFKB1GeneProductNFKB1 (HGNC)
NFKB2GeneProductNFKB2 (HGNC)
NFKBIAGeneProductNFKBIA (HGNC)
NKX3-1GeneProductNKX3-1 (HGNC)
NOS2GeneProductNOS2 (HGNC)
NOTCH1GeneProductNOTCH1 (HGNC)
NOTCH2GeneProductNOTCH2 (HGNC)
NOTCH3GeneProductNOTCH3 (HGNC)
NOTCH4GeneProductNOTCH4 (HGNC)
NQO1GeneProductNQO1 (HGNC)
NRASGeneProductNRAS (HGNC)
NTRK1GeneProductNTRK1 (HGNC)
Nitric oxideMetaboliteHMDB03378 (HMDB)
Notch signaling pathwayPathwayWP268 (WikiPathways)
PAMetaboliteC00416 (KEGG Compound)
PAX8GeneProductPAX8 (HGNC)
PDGFAGeneProductPDGFA (HGNC)
PDGFBGeneProductPDGFB (HGNC)
PDGFRAGeneProductPDGFRA (HGNC)
PDGFRBGeneProductPDGFRB (HGNC)
PGE2MetaboliteHMDB01220 (HMDB)
PGFGeneProductPGF (HGNC)
PI3K-Akt signaling pathwayPathwayWP4172 (KEGG Pathway)
PIK3CAGeneProductPIK3CA (HGNC)
PIK3CBGeneProductPIK3CB (HGNC)
PIK3CDGeneProductPIK3CD (HGNC)
PIK3R1GeneProductPIK3R1 (HGNC)
PIK3R2GeneProductPIK3R2 (HGNC)
PIK3R3GeneProductPIK3R3 (HGNC)
PIM1GeneProductPIM1 (HGNC)
PIM2GeneProductPIM2 (HGNC)
PIP3MetaboliteC05981 (KEGG Compound)
PLCB1GeneProductPLCB1 (HGNC)
PLCB2GeneProductPLCB2 (HGNC)
PLCB3GeneProductPLCB3 (HGNC)
PLCB4GeneProductPLCB4 (HGNC)
PLCG1GeneProductPLCG1 (HGNC)
PLCG2GeneProductPLCG2 (HGNC)
PLD1GeneProductPLD1 (HGNC)
PLD2GeneProductPLD2 (HGNC)
PLEKHG5GeneProductPLEKHG5 (HGNC)
PMAIP1GeneProductPMAIP1 (HGNC)
PMLGeneProductPML (HGNC)
POLKGeneProductPOLK (HGNC)
PPAR signaling pathwayPathwayWP3942 (WikiPathways)
PPARDGeneProductPPARD (HGNC)
PPARGGeneProductPPARG (HGNC)
PRKACAGeneProductPRKACA (HGNC)
PRKACBGeneProductPRKACB (HGNC)
PRKACGGeneProductPRKACG (HGNC)
PRKCAGeneProductPRKCA (HGNC)
PRKCBGeneProductPRKCB (HGNC)
PRKCGGeneProductPRKCG (HGNC)
PTCH1GeneProductPTCH1 (HGNC)
PTCH2GeneProductPTCH2 (HGNC)
PTENGeneProductPTEN (HGNC)
PTGER1GeneProductPTGER1 (HGNC)
PTGER2GeneProductPTGER2 (HGNC)
PTGER3GeneProductPTGER3 (HGNC)
PTGER4GeneProductPTGER4 (HGNC)
PTGS2GeneProductPTGS2 (HGNC)
PTK2GeneProductPTK2 (HGNC)
ProgesteroneMetaboliteHMDB01830 (HMDB)
RAC1GeneProductRAC1 (HGNC)
RAC2GeneProduct5880 (Entrez Gene)
RAC3GeneProductRAC3 (HGNC)
RAD51GeneProductRAD51 (HGNC)
RAF1GeneProductRAF1 (HGNC)
RALAGeneProductRALA (HGNC)
RALBP1GeneProductRALBP1 (HGNC)
RALBGeneProductRALB (HGNC)
RALGDSGeneProductRALGDS (HGNC)
RARAGeneProductRARA (HGNC)
RARBGeneProductRARB (HGNC)
RASGRP1GeneProductRASGRP1 (HGNC)
RASGRP2GeneProductRASGRP2 (HGNC)
RASGRP3GeneProductRASGRP3 (HGNC)
RASGRP4GeneProductRASGRP4 (HGNC)
RASSF1GeneProductRASSF1 (HGNC)
RASSF5GeneProductRASSF5 (HGNC)
RB1GeneProductRB1 (HGNC)
RBX1GeneProductRBX1 (HGNC)
RELAGeneProductRELA (HGNC)
RETGeneProductRET (HGNC)
RHOAGeneProductRHOA (HGNC)
ROCK1GeneProductROCK1 (HGNC)
ROCK2GeneProductROCK2 (HGNC)
RPS6KA5GeneProductRPS6KA5 (HGNC)
RPS6KB1GeneProductRPS6KB1 (HGNC)
RPS6KB2GeneProductRPS6KB2 (HGNC)
RUNX1GeneProductRUNX1 (HGNC)
RUNX1T1GeneProductRUNX1T1 (HGNC)
RXRAGeneProductRXRA (HGNC)
RXRBGeneProductRXRB (HGNC)
RXRGGeneProductRXRG (HGNC)
Retinoic AcidMetaboliteCHEBI:15367 (ChEBI)
SHHGeneProductSHH (HGNC)
SKP1GeneProductSKP1 (HGNC)
SKP2GeneProductSKP2 (HGNC)
SLC2A1GeneProductSLC2A1 (HGNC)
SMAD2GeneProductSMAD2 (HGNC)
SMAD3GeneProductSMAD3 (HGNC)
SMAD4GeneProductSMAD4 (HGNC)
SMOGeneProductSMO (HGNC)
SOS1GeneProductSOS1 (HGNC)
SOS2GeneProductSOS2 (HGNC)
SP1GeneProductENSG00000185591 (Ensembl)
SPI1GeneProductSPI1 (HGNC)
STAT1GeneProductSTAT1 (HGNC)
STAT2GeneProductSTAT2 (HGNC)
STAT3GeneProductSTAT3 (HGNC)
STAT4GeneProductSTAT4 (HGNC)
STAT5AGeneProductSTAT5A (HGNC)
STAT5BGeneProductSTAT5B (HGNC)
STAT6GeneProductSTAT6 (HGNC)
SUFUGeneProductSUFU (HGNC)
SuperoxideMetaboliteHMDB02168 (HMDB)
TCF7L1GeneProductTCF7L1 (HGNC)
TCF7L2GeneProductTCF7L2 (HGNC)
TCF7GeneProductTCF7 (HGNC)
TERCGeneProductTERC (HGNC)
TERTGeneProductTERT (HGNC)
TFGGeneProductTFG (HGNC)
TGF-beta signaling pathwayPathwayWP560 (WikiPathways)
TGFAGeneProductTGFA (HGNC)
TGFB1GeneProductTGFB1 (HGNC)
TGFB2GeneProductTGFB2 (HGNC)
TGFB3GeneProductTGFB3 (HGNC)
TGFBR1GeneProductTGFBR1 (HGNC)
TGFBR2GeneProductTGFBR2 (HGNC)
TP53GeneProductTP53 (HGNC)
TPM3GeneProductTPM3 (HGNC)
TPRGeneProductTPR (HGNC)
TRAF1GeneProductTRAF1 (HGNC)
TRAF2GeneProductTRAF2 (HGNC)
TRAF3GeneProductTRAF3 (HGNC)
TRAF4GeneProductTRAF4 (HGNC)
TRAF5GeneProductTRAF5 (HGNC)
TRAF6GeneProductTRAF6 (HGNC)
TXNRD1GeneProductTXNRD1 (HGNC)
TXNRD2GeneProductTXNRD2 (HGNC)
TXNRD3GeneProductTXNRD3 (HGNC)
TestosteroneMetaboliteHMDB00234 (HMDB)
VEGF signaling pathwayPathwayWP3888 (WikiPathways)
VEGFAGeneProductVEGFA (HGNC)
VEGFBGeneProductVEGFB (HGNC)
VEGFCGeneProductVEGFC (HGNC)
VEGFDGeneProductVEGFD (HGNC)
VHLGeneProductVHL (HGNC)
WNT10AGeneProductWNT10A (HGNC)
WNT10BGeneProductWNT10B (HGNC)
WNT11GeneProductWNT11 (HGNC)
WNT16GeneProductWNT16 (HGNC)
WNT1GeneProductWNT1 (HGNC)
WNT2BGeneProductWNT2B (HGNC)
WNT2GeneProductWNT2 (HGNC)
WNT3AGeneProductWNT3A (HGNC)
WNT3GeneProductWNT3 (HGNC)
WNT4GeneProductWNT4 (HGNC)
WNT5AGeneProductWNT5A (HGNC)
WNT5BGeneProductWNT5B (HGNC)
WNT6GeneProductWNT6 (HGNC)
WNT7AGeneProductWNT7A (HGNC)
WNT7BGeneProductWNT7B (HGNC)
WNT8AGeneProductWNT8A (HGNC)
WNT8BGeneProductWNT8B (HGNC)
WNT9AGeneProductWNT9A (HGNC)
WNT9BGeneProductWNT9B (HGNC)
Wnt signaling pathwayPathwayWP428 (WikiPathways)
XIAPGeneProductXIAP (HGNC)
ZBTB16GeneProductZBTB16 (HGNC)
ZBTB17GeneProductZBTB17 (HGNC)
cAMP signaling pathwayPathway
cAMPMetaboliteCHEBI:17489 (ChEBI)
fumarateMetaboliteCHEBI:29806 (ChEBI)
mTOR signaling pathwayPathwayWP3932 (WikiPathways)
p53 signaling pathwayPathway

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5434"
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