Regulation of actin cytoskeleton (Pan troglodytes)

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Growth Factor (GF)Focal complexassemblyGFActin polymerizationstress fiberActin polymerizationGene ExpressionStabilizationof actinGPCRChemotatic factorChemotactic factor?LamellipodiaActomyosinassembly contractionFilipodiaRASGPCR-pPI3KPI3KRTKFocal adhesionassemblystress fiber+pRASActin polymerizationRTKFGF5PAK1PIP2DOCK1INS2SSH1PDGFRBCHRM1CHRM3FGFR3PIP5K1CLOC100611792ITGA1RRAS2LPSPAK7EGFFGF8SSH3FGF7PIK3C2ASOS2FGF22AcetylcholineCSKCFL2VAV1LOC442775PIK3R2MAPK6PIK3R4FGF17PDGFBAdherens junctionpathwayFGF13PIK3CBWASF2BRAFFocal AdhesionpathwayPIK3C3FGF20GSNFGFR1WASRAF1PIK3CAGIT1RASSF7FGF16MYL1APCACTBFGFR4PDGFABradykininARHGEF6Focal AdhesionpathwayPXNACTBRRASFGF3GNA13FGF2PIK3R3BDKRB2PAK6FN1GNA12PDGFRALOC468536VCLINS1FGF10PIP5KL1PAK4RHOAACTN1ARPC5MYH10PIK3R1FGFR2LOC748477MSNMAPK SignalingpathwayARPC5FGF14FGF23LOC465655CYFIP2FGF6LOC470938ACTG1PIK3R5ACTBPIK3C2BF2RCHRM5KRASFGF4F2ARHGEF4FGF12MAP2K1ABI2PIP4K2ARAC3PPP1R12AIQGAP1PAK3CHRM4FGF11Apc2ENAHLIMK1LOC100609242TMSB4XACTG1CRKEGFRLOC460327MAPK1ARHGEF1DIAP3CFL1BDKRB1PIK3CGNRASACTG1PIP4K2BPIP3C3orf10PIP4K2ALOC748477RAC2LOC741907CDC42LOC456157MYLKPIP5K1BFGF9NCKAP1EZRCD14PIK3C2GPAK2ARHGEF6ROCK1SLC9A1PTK2RDXMOSFGF1ARHGEF7PIP5K1AMAPK3VIL1BAIAP2DIAP1FGF18SOS1FGF15WASF1PIP4K2CSSH2VCLPIK3CDCHRM2FGF21RAC1P4BCAR1BAIAP2PIP2ROCK2


Description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r45278) with a 80% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
128551view04:35, 12 February 2024EweitzModified title
114262view13:59, 2 January 2021EgonwThree more pathways clickable
72131view07:57, 25 October 2013Mkutmonadded datasource to pathway datanodes
71673view19:41, 17 October 2013MaintBotAutomated update of data sources
69266view18:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
48143view18:34, 9 May 2012MaintBotUpdating from human to fix xrefs
41574view02:00, 2 March 2011MaintBotRemoved redundant pathway information and comments
34302view22:05, 9 December 2009MaintBotAutomatic update of empty xrefs
33594view09:54, 1 December 2009MaintBotRemoved group label
31614view22:15, 13 August 2009MaintBotFixed text labels
30513view21:46, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI2GeneProduct459892 (Entrez Gene)
ACTBGeneProduct450133 (Entrez Gene)
ACTG1GeneProduct
ACTN1GeneProduct452993 (Entrez Gene)
APCGeneProduct461999 (Entrez Gene)
ARHGEF1GeneProduct
ARHGEF4GeneProduct470538 (Entrez Gene)
ARHGEF6GeneProduct
ARHGEF7GeneProduct452673 (Entrez Gene)
ARPC5GeneProduct457574 (Entrez Gene)
AcetylcholineMetabolite51-84-3 (CAS)
Adherens junction pathwayPathway
Apc2GeneProduct
BAIAP2GeneProduct454951 (Entrez Gene)
BCAR1GeneProduct454246 (Entrez Gene)
BDKRB1GeneProduct100612769 (Entrez Gene)
BDKRB2GeneProduct467547 (Entrez Gene)
BRAFGeneProduct463781 (Entrez Gene)
BradykininMetabolite58-82-2 (CAS)
C3orf10GeneProduct
CD14GeneProduct462118 (Entrez Gene)
CDC42GeneProduct
CFL1GeneProduct745772 (Entrez Gene)
CFL2GeneProduct452853 (Entrez Gene)
CHRM1GeneProduct451272 (Entrez Gene)
CHRM2GeneProduct463758 (Entrez Gene)
CHRM3GeneProduct469725 (Entrez Gene)
CHRM4GeneProduct
CHRM5GeneProduct503515 (Entrez Gene)
CRKGeneProduct747142 (Entrez Gene)
CSKGeneProduct453745 (Entrez Gene)
CYFIP2GeneProduct462221 (Entrez Gene)
DIAP1GeneProduct
DIAP3GeneProduct
DOCK1GeneProduct
EGFGeneProduct461435 (Entrez Gene)
EGFRGeneProduct463415 (Entrez Gene)
ENAHGeneProduct
EZRGeneProduct463100 (Entrez Gene)
F2GeneProduct451158 (Entrez Gene)
F2RGeneProduct471510 (Entrez Gene)
FGF10GeneProduct471553 (Entrez Gene)
FGF11GeneProduct748965 (Entrez Gene)
FGF12GeneProduct471041 (Entrez Gene)
FGF13GeneProduct465886 (Entrez Gene)
FGF1GeneProduct462158 (Entrez Gene)
FGF14GeneProduct739338 (Entrez Gene)
FGF15GeneProduct
FGF16GeneProduct473676 (Entrez Gene)
FGF17GeneProduct472708 (Entrez Gene)
FGF18GeneProduct
FGF20GeneProduct739665 (Entrez Gene)
FGF21GeneProduct468948 (Entrez Gene)
FGF22GeneProduct
FGF23GeneProduct747164 (Entrez Gene)
FGF2GeneProduct641462 (Entrez Gene)
FGF3GeneProduct466693 (Entrez Gene)
FGF4GeneProduct747727 (Entrez Gene)
FGF5GeneProduct471190 (Entrez Gene)
FGF6GeneProduct747181 (Entrez Gene)
FGF7GeneProduct744975 (Entrez Gene)
FGF8GeneProduct
FGF9GeneProduct744731 (Entrez Gene)
FGFR1GeneProduct464122 (Entrez Gene)
FGFR2GeneProduct466220 (Entrez Gene)
FGFR3GeneProduct461067 (Entrez Gene)
FGFR4GeneProduct462301 (Entrez Gene)
FN1GeneProduct459926 (Entrez Gene)
Focal Adhesion pathwayPathwayWP306 (WikiPathways)
GIT1GeneProduct454549 (Entrez Gene)
GNA12GeneProduct463234 (Entrez Gene)
GNA13GeneProduct454827 (Entrez Gene)
GSNGeneProduct464706 (Entrez Gene)
INS1GeneProduct
INS2GeneProduct
IQGAP1GeneProduct467762 (Entrez Gene)
ITGA1GeneProduct461880 (Entrez Gene)
KRASGeneProduct473387 (Entrez Gene)
LIMK1GeneProduct463466 (Entrez Gene)
LOC100609242GeneProduct100609242 (Entrez Gene)
LOC100611792GeneProduct100611792 (Entrez Gene)
LOC442775GeneProduct
LOC456157GeneProduct456157 (Entrez Gene)
LOC460327GeneProduct460327 (Entrez Gene)
LOC465655GeneProduct465655 (Entrez Gene)
LOC468536GeneProduct468536 (Entrez Gene)
LOC470938GeneProduct470938 (Entrez Gene)
LOC741907GeneProduct741907 (Entrez Gene)
LOC748477GeneProduct748477 (Entrez Gene)
LPSMetaboliteC00338 (KEGG Compound)
MAP2K1GeneProduct450188 (Entrez Gene)
MAPK Signaling pathwayPathwayWP382 (WikiPathways)
MAPK1GeneProduct458680 (Entrez Gene)
MAPK3GeneProduct454037 (Entrez Gene)
MAPK6GeneProduct453439 (Entrez Gene)
MOSGeneProduct472772 (Entrez Gene)
MSNGeneProduct
MYH10GeneProduct455090 (Entrez Gene)
MYL1GeneProduct459915 (Entrez Gene)
MYLKGeneProduct460640 (Entrez Gene)
NCKAP1GeneProduct459801 (Entrez Gene)
NRASGeneProduct742713 (Entrez Gene)
PAK1GeneProduct451439 (Entrez Gene)
PAK2GeneProduct460965 (Entrez Gene)
PAK3GeneProduct450118 (Entrez Gene)
PAK4GeneProduct
PAK6GeneProduct453327 (Entrez Gene)
PAK7GeneProduct469876 (Entrez Gene)
PDGFAGeneProduct
PDGFBGeneProduct458844 (Entrez Gene)
PDGFRAGeneProduct
PDGFRBGeneProduct462188 (Entrez Gene)
PIK3C2AGeneProduct451052 (Entrez Gene)
PIK3C2BGeneProduct457657 (Entrez Gene)
PIK3C2GGeneProduct
PIK3C3GeneProduct455385 (Entrez Gene)
PIK3CAGeneProduct460858 (Entrez Gene)
PIK3CBGeneProduct
PIK3CDGeneProduct457922 (Entrez Gene)
PIK3CGGeneProduct463649 (Entrez Gene)
PIK3R1GeneProduct461836 (Entrez Gene)
PIK3R2GeneProduct455855 (Entrez Gene)
PIK3R3GeneProduct456565 (Entrez Gene)
PIK3R4GeneProduct460692 (Entrez Gene)
PIK3R5GeneProduct455085 (Entrez Gene)
PIP2MetaboliteC04637 (KEGG Compound)
PIP3MetaboliteC05981 (KEGG Compound)
PIP4K2AGeneProduct742458 (Entrez Gene)
PIP4K2BGeneProduct746830 (Entrez Gene)
PIP4K2CGeneProduct467044 (Entrez Gene)
PIP5K1AGeneProduct457288 (Entrez Gene)
PIP5K1BGeneProduct464513 (Entrez Gene)
PIP5K1CGeneProduct455590 (Entrez Gene)
PIP5KL1GeneProduct464758 (Entrez Gene)
PPP1R12AGeneProduct452095 (Entrez Gene)
PTK2GeneProduct464422 (Entrez Gene)
PXNGeneProduct452303 (Entrez Gene)
RAC1P4GeneProduct
RAC2GeneProduct
RAC3GeneProduct
RAF1GeneProduct460182 (Entrez Gene)
RASSF7GeneProduct466303 (Entrez Gene)
RDXGeneProduct466776 (Entrez Gene)
RHOAGeneProduct461014 (Entrez Gene)
ROCK1GeneProduct455326 (Entrez Gene)
ROCK2GeneProduct470307 (Entrez Gene)
RRAS2GeneProduct451038 (Entrez Gene)
RRASGeneProduct468955 (Entrez Gene)
SLC9A1GeneProduct456669 (Entrez Gene)
SOS1GeneProduct459171 (Entrez Gene)
SOS2GeneProduct452897 (Entrez Gene)
SSH1GeneProduct467124 (Entrez Gene)
SSH2GeneProduct454551 (Entrez Gene)
SSH3GeneProduct451365 (Entrez Gene)
TMSB4XGeneProduct
VAV1GeneProduct455647 (Entrez Gene)
VCLGeneProduct450531 (Entrez Gene)
VIL1GeneProduct470646 (Entrez Gene)
WASGeneProduct
WASF1GeneProduct462935 (Entrez Gene)
WASF2GeneProduct456675 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP944"
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