GLP-1 in pancreatic islet cells (Homo sapiens)
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Description
Factors in GLP-1 production in pancreatic alpha cells, and the hypothetical function of resulting GLP-1 in pancreatic beta cells. Based on Figure 3 in https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190119.
Quality Tags
Ontology Terms
Bibliography
- Davis EM, Sandoval DA; ''Glucagon-like peptide-1: Actions and influence on pancreatic hormone function''; Comprehensive Physiology, 2020 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Diabetes | |||
Exercise | |||
GCG | GeneProduct | ||
GLP-1 | Protein | ||
GLP1R | GeneProduct | ||
Glucose | Metabolite | ||
Hyperglycemia | |||
IL6 | GeneProduct | ||
IL6R | GeneProduct | ||
INS | GeneProduct | ||
Insulin | Protein | ||
Metabolic stress | |||
Obesity | |||
Proliferation | |||
SLC2A1 | GeneProduct | ||
SLC2A2 | GeneProduct | ||
Systematic inflammation |
Annotated Interactions
No annotated interactions