TCA cycle - detailed (Saccharomyces cerevisiae)

Jump to: navigation, search

The tricarboxylic acid (TCA) cycle is a catabolic pathway that functions to generate energy and reduced cofactors from the oxidative decarboxylation of acetyl (C2) units. It occupies a central role in the metabolism of aerobic organisms, enabling the production of energy from carbohydrates, fatty acids, amino acids, and potentially any other molecule that can be converted or broken down to acetyl-CoA. In addition to its role in catabolism, the TCA cycle can also serve a biosynthetic role, as several intermediates in the pathway (e.g. oxaloacetate, succinate) provide carbon for the synthesis of amino acids or other biological compounds. Source: https://pathway.yeastgenome.org/