Retinoid metabolism in retina: healthy vs. RLBP1-deficient (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Cone cell11cisREatREatREatROL11cisROLCralbpa11cisRALatRALatROLatRAL11cisRALatRALatROLCralbpaatROLCralbpa11cisRAL11cisRALCralbpaatROLatRALatROLRod cellMueller cellRetinal pigment epithelial cellName: Retinoid metabolism in retinaOrganism: Homo sapiens


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Bibliography

  1. Schlegel DK, Ramkumar S, von Lintig J, Neuhauss SC; ''Disturbed retinoid metabolism upon loss of rlbp1a impairs cone function and leads to subretinal lipid deposits and photoreceptor degeneration in the zebrafish retina.''; Elife, 2021 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
138396view20:23, 5 April 2025EweitzBold 11cisRE, connect unhealthy rod cell atRAL to MGC complex
138357view23:46, 31 March 2025EweitzRefine interactions
138356view23:44, 31 March 2025EweitzOntology Term : 'Newfoundland cone-rod dystrophy' added !
138355view23:43, 31 March 2025EweitzOntology Term : 'fundus albipunctatus' added !
138354view23:43, 31 March 2025EweitzOntology Term : 'retinitis pigmentosa' added !
138353view23:42, 31 March 2025EweitzOntology Term : 'Mueller cell' added !
138352view23:42, 31 March 2025EweitzOntology Term : 'retinal pigment epithelial cell' added !
138351view23:42, 31 March 2025EweitzOntology Term : 'compound eye cone cell' added !
138350view23:42, 31 March 2025EweitzOntology Term : 'retinal rod cell' added !
138349view23:41, 31 March 2025EweitzModified title
138348view23:41, 31 March 2025EweitzModified description
138347view23:39, 31 March 2025EweitzAdd literature reference
138346view23:37, 31 March 2025EweitzClarify deficiency
138345view23:25, 31 March 2025EweitzDuplicate for comparison group
138344view23:13, 31 March 2025EweitzLabel cell types
138341view12:47, 31 March 2025EweitzNew pathway

External references

DataNodes

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Name  ↓Type  ↓Database reference  ↓Comment  ↓
11cisRALMetaboliteCHEBI:16066 (ChEBI)
11cisREMetaboliteCHEBI:195358 (ChEBI)
11cisROLMetaboliteCHEBI:46856 (ChEBI)
CralbpaGeneProduct
atRALMetaboliteCHEBI:17898 (ChEBI)
atREMetaboliteCHEBI:63410 (ChEBI)
atROLMetaboliteCHEBI:17336 (ChEBI)

Annotated Interactions

No annotated interactions

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