Caffeine synthesis (Theobroma cacao)

Revision as of 01:36, 17 September 2025 by Hayashi (Talk | contribs)

Description

Theobroma cacao caffeine synthesis

[Convergent Biochemical Pathways for Xanthine Alkaloid Production in Plants Evolved from Ancestral Enzymes with Different Catalytic Properties](https://pmc.ncbi.nlm.nih.gov/articles/PMC8233510/)

[Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes](https://pmc.ncbi.nlm.nih.gov/articles/PMC5035902/)

View approved pathways at the new wikipathways.org.

O'Donnell AJ, Huang R, Barboline JJ, Barkman TJ; ''Convergent Biochemical Pathways for Xanthine Alkaloid Production in Plants Evolved from Ancestral Enzymes with Different Catalytic Properties.''; Mol Biol Evol, 2021 PubMed Europe PMC Scholia
Huang R, O'Donnell AJ, Barboline JJ, Barkman TJ; ''Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes.''; Proc Natl Acad Sci U S A, 2016 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
141385	view	14:14, 11 November 2025	Eweitz	Modified title
140941	view	11:52, 30 October 2025	Eweitz	Standardize case
140940	view	11:51, 30 October 2025	Eweitz	Economize layout
140737	view	10:01, 18 October 2025	Egonw	Ontology Term : 'classic metabolic pathway' added !
140736	view	10:01, 18 October 2025	Egonw	Added metabolite IDs
140734	view	09:58, 18 October 2025	Egonw	modified description
140609	view	09:46, 17 September 2025	MaintBot	Species updated
140594	view	01:36, 17 September 2025	Hayashi	New pathway

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Name	Type	Database reference	Comment
3-methylxanthine	Metabolite
TcCS1	GeneProduct
TcCS2	GeneProduct
Theobromine	Metabolite
Xanthin	Metabolite
caffeine	Metabolite

No annotated interactions