Voltage-gated sodium channel action potential (Homo sapiens)

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Description

This pathway depicts the details of the structure of sodium channels(Nav) and the relation of channel state and action potential.

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Ontology Terms

 

Bibliography

  1. Fan X, Huang J, Jin X, Yan N; ''Cryo-EM structure of human voltage-gated sodium channel Na(v)1.6.''; Proc Natl Acad Sci U S A, 2023 PubMed Europe PMC Scholia
  2. Cantrell AR, Tibbs VC, Yu FH, Murphy BJ, Sharp EM, Qu Y, Catterall WA, Scheuer T; ''Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C andprotein kinase A anchored to AKAP-15.''; Mol Cell Neurosci, 2002 PubMed Europe PMC Scholia
  3. Catterall WA; ''Molecular properties of voltage-sensitive sodium channels.''; Annu Rev Biochem, 1986 PubMed Europe PMC Scholia
  4. Marieskind HI, Ehrenreich B; ''Toward socialist medicine: the women's health movement.''; Soc Policy, 1975 PubMed Europe PMC Scholia
  5. Cusdin FS, Clare JJ, Jackson AP; ''Trafficking and cellular distribution of voltage-gated sodium channels.''; Traffic, 2008 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
140797view02:08, 29 October 2025EweitzOntology Term : 'neuron' added !
140613view12:28, 17 September 2025Duanchange the reference
140612view12:27, 17 September 2025DuanNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKAP7GeneProductENSG00000118507 (Ensembl)
DI
DII
DIII
DIV
NH3(+)MetaboliteCHEBI:29421 (ChEBI)
Na+MetaboliteCHEBI:29101 (ChEBI)
Nav DIIIProteinPF00520 (InterPro)
Nav DIIProteinPF00520 (InterPro)
Nav DIProteinPF00520 (InterPro)
Nav DIVProteinPF00520 (InterPro)
PRKACAGeneProductENSG00000072062 (Ensembl)
PRKCAGeneProductENSG00000154229 (Ensembl)
SCN1BProteinQ07699 (InterPro)
[CO2](.-)MetaboliteCHEBI:29325 (ChEBI)
arginine monocationMetaboliteCHEBI:32696 (ChEBI)
tetrodotoxineMetaboliteCHEBI:9506 (ChEBI)

Annotated Interactions

No annotated interactions

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