Voltage-gated sodium channel action potential (Homo sapiens)
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Description
This pathway depicts the details of the structure of sodium channels(Nav) and the relation of channel state and action potential.
Quality Tags
Ontology Terms
Bibliography
- Fan X, Huang J, Jin X, Yan N; ''Cryo-EM structure of human voltage-gated sodium channel Na(v)1.6.''; Proc Natl Acad Sci U S A, 2023 PubMed Europe PMC Scholia
- Cantrell AR, Tibbs VC, Yu FH, Murphy BJ, Sharp EM, Qu Y, Catterall WA, Scheuer T; ''Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C andprotein kinase A anchored to AKAP-15.''; Mol Cell Neurosci, 2002 PubMed Europe PMC Scholia
- Catterall WA; ''Molecular properties of voltage-sensitive sodium channels.''; Annu Rev Biochem, 1986 PubMed Europe PMC Scholia
- Marieskind HI, Ehrenreich B; ''Toward socialist medicine: the women's health movement.''; Soc Policy, 1975 PubMed Europe PMC Scholia
- Cusdin FS, Clare JJ, Jackson AP; ''Trafficking and cellular distribution of voltage-gated sodium channels.''; Traffic, 2008 PubMed Europe PMC Scholia
History
External references
DataNodes
| View all... |
| Name | Type | Database reference | Comment |
|---|---|---|---|
| AKAP7 | GeneProduct | ENSG00000118507 (Ensembl) ![]() | |
| DI | |||
| DII | |||
| DIII | |||
| DIV | |||
| NH3(+) | Metabolite | CHEBI:29421 (ChEBI) ![]() | |
| Na+ | Metabolite | CHEBI:29101 (ChEBI) ![]() | |
| Nav DIII | Protein | PF00520 (InterPro) ![]() | |
| Nav DII | Protein | PF00520 (InterPro) ![]() | |
| Nav DI | Protein | PF00520 (InterPro) ![]() | |
| Nav DIV | Protein | PF00520 (InterPro) ![]() | |
| PRKACA | GeneProduct | ENSG00000072062 (Ensembl) ![]() | |
| PRKCA | GeneProduct | ENSG00000154229 (Ensembl) ![]() | |
| SCN1B | Protein | Q07699 (InterPro) ![]() | |
| [CO2](.-) | Metabolite | CHEBI:29325 (ChEBI) ![]() | |
| arginine monocation | Metabolite | CHEBI:32696 (ChEBI) ![]() | |
| tetrodotoxine | Metabolite | CHEBI:9506 (ChEBI) ![]() |
Annotated Interactions
No annotated interactions
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