IL-3 signaling pathway (Rattus norvegicus)

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DDDDeubiquitinationMTDDAutophosphorylationEndosomeDemethylationDCY->PM(Protein-protein interaction)Molecule in the pathwayMitochondrionEnzyme complexControlMADMADUbiquitinationActivationDERPlasma membraneDephosphorylationRecruitmentProteolytic cleavageNUMADeacetylationDReceptorGlycosylationAccession Number: NetPath 15DesumoylationDCY->NUGOReaction through unknown mechanisms/moleculesEndoplasmic reticulumDDDCY->PMAcetylationDMAInhibitionDPhosphorylationPalmitoylationLigandDCY->NUSumoylationProteins in a complex interactionPMNucleusExtracellularCytoplasmTranslocationMADMethylationGolgi apparatusMolecular AssociationCYENMT->CYDCY->PMMAECMapk1Hspb1Gnb2l1Mapkapk2Il3raHckRac1PILRBBcl2l1Bcl2YwhazBaxLynTYK2Chek1RAPGEF1Akt1Stat3RPS6KB2PrkcaYWHAQSocs2Shc1CrklPpp2caCDC42Sos1BadIL3Pik3cdHrasPik3r2PrkcbStat5bStat1Kcnip3Tnfrsf1bPxnId1Nfkb1Gsk3bBmxAtf2CblCsf2rbKrasPrkacaMrasAtf1IL3YwhabMmp2SrcPIK3CAMapk3VclMapk8Vav1Socs3Il3raStat5aPtk2Gene SymbolSelpJak2BIRC5Gab2Bcl2l11TecRxraMapk3Creb1Gsk3aGata2Shc1Nfkb1Map2k1RaraGata1Mapk14BadFoxo1Ptpn11Mmp9Slc2a1Pik3r1IL3Ptpn6FesFcer2Jak1Inpp5dMAPK7Mapk9Grb2Rap1aStat6Dnm1LckRaf1Csf2rbIL3Pak1SykCrkRac2MatkGab1PrkcaSlc2a1FynSfpi1Cish


Description

No description

Comments

GenMAPP notes 
NetPath:15 - IL-3 Signaling Pathway. NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP286(r21281) with a 87% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
116984view10:45, 16 May 2021EweitzModified title
69359view18:53, 8 July 2013MaintBotUpdated to 2013 gpml schema
67375view10:44, 26 June 2013Christine ChichesterOntology Term : 'interleukin-3 signaling pathway' added !
41672view02:35, 2 March 2011MaintBotRemoved redundant pathway information and comments
35790view06:54, 13 February 2010MaintBotAdded description
34064view19:07, 9 December 2009MaintBotAutomatic update of empty xrefs
31430view21:01, 13 August 2009MaintBotFixed text labels
30976view00:51, 30 July 2009MaintBotConverted from Homo sapiens
21351view11:31, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:IL-3 NetPath 15]] moved to [[Pathway:WP319]]: Moved to stable identifier
8174view13:46, 7 January 2008MaintBot[[Pathway:Rat:IL-3 NetPath 15]] moved to [[Pathway:Rattus norvegicus:IL-3 NetPath 15]]: Renaming species
7707view16:11, 18 December 2007MaintBotfixed category names
7246view12:41, 4 November 2007MaintBotAdded categories to GPML
6560view22:20, 22 May 2007A.Pandeygpml file for [[Rat:IL-3_NetPath_15]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Akt1GeneProduct24185 (Entrez Gene)
Atf1GeneProduct315305 (Entrez Gene)
Atf2GeneProduct81647 (Entrez Gene)
BIRC5GeneProduct
BadGeneProduct64639 (Entrez Gene)
BaxGeneProduct24887 (Entrez Gene)
Bcl2GeneProduct24224 (Entrez Gene)
Bcl2l11GeneProduct64547 (Entrez Gene)
Bcl2l1GeneProduct24888 (Entrez Gene)
BmxGeneProduct367786 (Entrez Gene)
CDC42GeneProduct
CblGeneProduct500985 (Entrez Gene)
Chek1GeneProduct140583 (Entrez Gene)
CishGeneProduct83681 (Entrez Gene)
Creb1GeneProduct81646 (Entrez Gene)
CrkGeneProduct54245 (Entrez Gene)
CrklGeneProduct287942 (Entrez Gene)
Csf2rbGeneProduct171081 (Entrez Gene)
Dnm1GeneProduct140694 (Entrez Gene)
Fcer2GeneProduct171075 (Entrez Gene)
FesGeneProduct361597 (Entrez Gene)
Foxo1GeneProduct84482 (Entrez Gene)
FynGeneProduct25150 (Entrez Gene)
Gab1GeneProduct361388 (Entrez Gene)
Gab2GeneProduct84477 (Entrez Gene)
Gata1GeneProduct25172 (Entrez Gene)
Gata2GeneProduct25159 (Entrez Gene)
Gene SymbolGeneProduct
Gnb2l1GeneProduct83427 (Entrez Gene)
Grb2GeneProduct81504 (Entrez Gene)
Gsk3aGeneProduct50686 (Entrez Gene)
Gsk3bGeneProduct84027 (Entrez Gene)
HckGeneProduct25734 (Entrez Gene)
HrasGeneProduct293621 (Entrez Gene)
Hspb1GeneProduct24471 (Entrez Gene)
IL3GeneProduct
Id1GeneProduct25261 (Entrez Gene)
Il3raGeneProduct246144 (Entrez Gene)
Inpp5dGeneProduct54259 (Entrez Gene)
Jak1GeneProduct84598 (Entrez Gene)
Jak2GeneProduct24514 (Entrez Gene)
Kcnip3GeneProduct65199 (Entrez Gene)
KrasGeneProduct24525 (Entrez Gene)
LckGeneProduct313050 (Entrez Gene)
LynGeneProduct81515 (Entrez Gene)
MAPK7GeneProduct
Map2k1GeneProduct170851 (Entrez Gene)
Mapk1GeneProduct116590 (Entrez Gene)
Mapk14GeneProduct81649 (Entrez Gene)
Mapk3GeneProduct50689 (Entrez Gene)
Mapk8GeneProduct116554 (Entrez Gene)
Mapk9GeneProduct50658 (Entrez Gene)
Mapkapk2GeneProduct289014 (Entrez Gene)
MatkGeneProduct60450 (Entrez Gene)
Mmp2GeneProduct81686 (Entrez Gene)
Mmp9GeneProduct81687 (Entrez Gene)
MrasGeneProduct25482 (Entrez Gene)
Nfkb1GeneProduct81736 (Entrez Gene)
PIK3CAGeneProduct
PILRBGeneProduct
Pak1GeneProduct29431 (Entrez Gene)
Pik3cdGeneProduct366508 (Entrez Gene)
Pik3r1GeneProduct25513 (Entrez Gene)
Pik3r2GeneProduct29741 (Entrez Gene)
Ppp2caGeneProduct24672 (Entrez Gene)
PrkacaGeneProduct25636 (Entrez Gene)
PrkcaGeneProduct24680 (Entrez Gene)
PrkcbGeneProduct25023 (Entrez Gene)
Ptk2GeneProduct25614 (Entrez Gene)
Ptpn11GeneProduct25622 (Entrez Gene)
Ptpn6GeneProduct116689 (Entrez Gene)
PxnGeneProduct360820 (Entrez Gene)
RAPGEF1GeneProduct
RPS6KB2GeneProduct
Rac1GeneProduct363875 (Entrez Gene)
Rac2GeneProduct366957 (Entrez Gene)
Raf1GeneProduct24703 (Entrez Gene)
Rap1aGeneProduct295347 (Entrez Gene)
RaraGeneProduct24705 (Entrez Gene)
RxraGeneProduct25271 (Entrez Gene)
SelpGeneProduct25651 (Entrez Gene)
Sfpi1GeneProduct366126 (Entrez Gene)
Shc1GeneProduct85385 (Entrez Gene)
Slc2a1GeneProduct24778 (Entrez Gene)
Socs2GeneProduct84607 (Entrez Gene)
Socs3GeneProduct89829 (Entrez Gene)
Sos1GeneProduct313845 (Entrez Gene)
SrcGeneProduct83805 (Entrez Gene)
Stat1GeneProduct25124 (Entrez Gene)
Stat3GeneProduct25125 (Entrez Gene)
Stat5aGeneProduct24918 (Entrez Gene)
Stat5bGeneProduct25126 (Entrez Gene)
Stat6GeneProduct362896 (Entrez Gene)
SykGeneProduct25155 (Entrez Gene)
TYK2GeneProduct
TecGeneProduct84492 (Entrez Gene)
Tnfrsf1bGeneProduct156767 (Entrez Gene)
Vav1GeneProduct25156 (Entrez Gene)
VclGeneProduct305679 (Entrez Gene)
YWHAQGeneProduct
YwhabGeneProduct56011 (Entrez Gene)
YwhazGeneProduct25578 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP319"
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