Oxidative stress response (Bos taurus)

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Reactive Oxygen SpeciesInduction of
antioxidant genes
Stress-regulated MAP kinaseAdaptive responseRepression of ROS-
producing systemsTF inhibitionInhibition of oxidasesImmediate-early
gene inductionTF activationActivationRepressionNFKB1TXNRD1FOSUGT1A6GCLCMAPK10MT1XGSTT2GSRHMOX1NQO1MAOAGPX3GPX1MAPK14SOD2Nrf2SOD3MGST1TXN2SP1NFIXSOD1CYP1A1CYBACATXDHJUNBTXNRD2


Description

No description

Comments

GenMAPP notes 
Adapted from Biochem J 1999 Sep 15;342 Pt 3:481-96 Morel Y, Barouki R. Repression of gene expression by oxidative stress. Biochem J 1999 Sep 15;342 Pt 3:481-96
GenMAPP remarks 
Adapted from rat by GenMAPP.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP408(r21540) with a 86% conversion rate.

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Ontology Terms

 

Bibliography

  1. Morel Y, Barouki R; ''Repression of gene expression by oxidative stress.''; Biochem J, 1999 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117036view14:11, 16 May 2021EweitzModified title
80921view15:31, 30 June 2015Mkutmonhomology conversion
71403view19:00, 17 October 2013MaintBotAutomated update of data sources
63336view21:13, 9 May 2013MaintBotUpdated to 2013 gpml schema
40516view19:29, 1 March 2011MaintBotRemoved redundant pathway information and comments
33759view00:02, 9 December 2009MaintBotAutomatic update of empty xrefs
32514view12:53, 17 August 2009MaintBotFixed text labels
32202view12:38, 15 August 2009MaintBotFixed text labels
31685view11:45, 14 August 2009MaintBotFixed group labels
31212view19:37, 13 August 2009MaintBotFixed text labels
30619view22:22, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CATGeneProduct531682 (Entrez Gene)
CYBAGeneProduct281111 (Entrez Gene) Probe set ID: u18729
CYP1A1GeneProduct282870 (Entrez Gene)
FOSGeneProduct280795 (Entrez Gene)
GCLCGeneProduct512468 (Entrez Gene)
GPX1GeneProduct281209 (Entrez Gene)
GPX3GeneProduct281210 (Entrez Gene)
GSRGeneProduct506406 (Entrez Gene)
GSTT2GeneProduct
HMOX1GeneProduct513221 (Entrez Gene)
JUNBGeneProduct514246 (Entrez Gene)
MAOAGeneProduct281293 (Entrez Gene)
MAPK10GeneProduct537631 (Entrez Gene)
MAPK14GeneProduct534492 (Entrez Gene)
MGST1GeneProduct493719 (Entrez Gene)
MT1XGeneProduct
NFIXGeneProduct536348 (Entrez Gene)
NFKB1GeneProduct616115 (Entrez Gene)
NQO1GeneProduct519632 (Entrez Gene)
Nrf2GeneProduct
SOD1GeneProduct
SOD2GeneProduct281496 (Entrez Gene)
SOD3GeneProduct532481 (Entrez Gene)
SP1GeneProduct540741 (Entrez Gene)
TXN2GeneProduct281557 (Entrez Gene)
TXNRD1GeneProduct282388 (Entrez Gene)
TXNRD2GeneProduct282389 (Entrez Gene)
UGT1A6GeneProduct286792 (Entrez Gene)
XDHGeneProduct280960 (Entrez Gene)

Annotated Interactions

No annotated interactions
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