G1 to S cell cycle control (Gallus gallus)

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bCyclin DspG1/S transition PhaseE2fphosphorylation of proteinsinvolved in G1/S transitionRbG1/S transition CyclinDependent KinasesG1 PhaseG1 CyclinDependant CyclasesDNA replicationpuG1/S Cell Cycleorigin recognition complexTTTCC/GCGCuDegradationCyclin EseCell cycle DNA replication genespcakpCheckpointdp1bpeDNA polymerasesupinactiveG2 Phase-M phaseE2F6CdkCDKN2BCCNHRB1CDC25ACDKN2DTPTERBL1CDK7ORC1LRB1ORC3LCCND1RCJMB04_6d17E2F2TP53CDKMCM4E2F1CDKORC2LCREB3MYT1CDKN1CE2fMNAT1CDKN2ACDKN1BPOLE2CCND3GADD45ACDKN2CCDK7CDC45LCDK6ORC4LMCM2CREB1CCNE2CCNE1E2fATMCDK2POLEPRIM2CCNB1TFDP1RB1MCM3CDKN1APRIM1TP53CyclinDCCND2E2F3PCNACREB3L1MCM5CCNE1MDM2WEE1CDK6CyclinDORC6LCDK4TFDP2ORC5LMYCCREBL1MCM6CdkCCNE1E2F4RPA3TPTECCNG2RCJMB04_30p22RPA1POLA2MCM7CREB3L3TFDP1CDK4CCNA1CREB3L4


Description

No description

Comments

GenMAPP notes 
Adapted from http://www.genomeknowledge.org/, and Maeda et al. Journal of Invest Dermatol. 2002. 119:22-26.
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP45(r20771) with a 66% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Maeda T, Hanna AN, Sim AB, Chua PP, Chong MT, Tron VA; ''GADD45 regulates G2/M arrest, DNA repair, and cell death in keratinocytes following ultraviolet exposure.''; J Invest Dermatol, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
95750view13:54, 19 January 2018MkutmonHomology conversion update
74229view16:23, 8 April 2014EgonwRemoved a data source where no ID was given.
68801view17:14, 8 July 2013MaintBotUpdated to 2013 gpml schema
67271view10:29, 26 June 2013Christine ChichesterOntology Term : 'G1/S DNA damage checkpoint pathway' added !
47792view16:31, 6 April 2012Khanspersupdated xrefs
40934view22:52, 1 March 2011MaintBotRemoved redundant pathway information and comments
35830view22:15, 17 February 2010KhanspersAdded lit ref
35829view22:14, 17 February 2010KhanspersModified description
33865view17:48, 9 December 2009MaintBotAutomatic update of empty xrefs
33510view15:16, 30 November 2009MaintBotRemoved group label
31551view21:52, 13 August 2009MaintBotFixed text labels
30409view21:12, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATMGeneProduct395401 (Entrez Gene)
CCNA1GeneProduct418901 (Entrez Gene)
CCNB1GeneProduct
CCND1GeneProduct396341 (Entrez Gene)
CCND2GeneProduct374047 (Entrez Gene)
CCND3GeneProduct419928 (Entrez Gene)
CCNE1GeneProduct426117 (Entrez Gene)
CCNE2GeneProduct420231 (Entrez Gene)
CCNG2GeneProduct422512 (Entrez Gene)
CCNHGeneProduct427328 (Entrez Gene)
CDC25AGeneProduct420375 (Entrez Gene)
CDC45LGeneProduct416776 (Entrez Gene)
CDKGeneProduct
CDK2GeneProduct
CDK4GeneProduct
CDK6GeneProduct420558 (Entrez Gene)
CDK7GeneProduct
CDKN1AGeneProduct
CDKN1BGeneProduct
CDKN1CGeneProduct
CDKN2AGeneProduct
CDKN2BGeneProduct395076 (Entrez Gene)
CDKN2CGeneProduct429104 (Entrez Gene)
CDKN2DGeneProduct
CREB1GeneProduct395099 (Entrez Gene)
CREB3GeneProduct427417 (Entrez Gene)
CREB3L1GeneProduct423198 (Entrez Gene)
CREB3L3GeneProduct428333 (Entrez Gene)
CREB3L4GeneProduct
CREBL1GeneProduct
CdkGeneProduct
CyclinDGeneProduct
E2F1GeneProduct396142 (Entrez Gene)
E2F2GeneProduct
E2F3GeneProduct420824 (Entrez Gene)
E2F4GeneProduct769430 (Entrez Gene)
E2F6GeneProduct
E2fGeneProduct
GADD45AGeneProduct
MCM2GeneProduct416027 (Entrez Gene)
MCM3GeneProduct422043 (Entrez Gene)
MCM4GeneProduct426764 (Entrez Gene)
MCM5GeneProduct418058 (Entrez Gene)
MCM6GeneProduct424295 (Entrez Gene)
MCM7GeneProduct
MDM2GeneProduct
MNAT1GeneProduct423521 (Entrez Gene)
MYCGeneProduct420332 (Entrez Gene)
MYT1GeneProduct419249 (Entrez Gene)
ORC1LGeneProduct424640 (Entrez Gene)
ORC2LGeneProduct424077 (Entrez Gene)
ORC3LGeneProduct421822 (Entrez Gene)
ORC4LGeneProduct424307 (Entrez Gene)
ORC5LGeneProduct417714 (Entrez Gene)
ORC6LGeneProduct415749 (Entrez Gene)
PCNAGeneProduct373984 (Entrez Gene)
POLA2GeneProduct
POLE2GeneProduct423567 (Entrez Gene)
POLEGeneProduct416997 (Entrez Gene)
PRIM1GeneProduct426646 (Entrez Gene)
PRIM2GeneProduct421878 (Entrez Gene)
RB1GeneProduct386582 (Entrez Gene)
RBL1GeneProduct419126 (Entrez Gene)
RCJMB04_30p22GeneProduct420206 (Entrez Gene)
RCJMB04_6d17GeneProduct419566 (Entrez Gene)
RPA1GeneProduct417563 (Entrez Gene)
RPA3GeneProduct420578 (Entrez Gene)
TFDP1GeneProduct418739 (Entrez Gene)
TFDP2GeneProduct424780 (Entrez Gene)
TP53GeneProduct
TPTEGeneProduct418885 (Entrez Gene)
WEE1GeneProduct423045 (Entrez Gene)

Annotated Interactions

No annotated interactions
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