ACE inhibitor pathway (Pan troglodytes)
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1
Cell Membrane
AGTR2
Bradykinin
ACE
KNG1
AGT
REN
ACE Inhibitor
AGTR1
ACE
BDKRB2
Angiotensin II
Aldosterone
Angiotensin I
NOS3
Description
No description
Comments
GenMAPP notes
https://www.pharmgkb.org/search/pathway/ace-inhibitor.jsp
Model non-tissue specific cell displaying genes which may be involved in the ACE inhibitor pathway.
GenMAPP remarks
Adapted from PharmGKB (right click for info)
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP554(r30178)
with a 88% conversion rate.
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Bibliography
Hamming I, Cooper ME, Haagmans BL, Hooper NM, Korstanje R, Osterhaus AD, Timens W, Turner AJ, Navis G, van Goor H; ''The emerging role of ACE2 in physiology and disease.''; J Pathol, 2007
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
117381
view
10:31, 21 May 2021
Eweitz
Modified title
106934
view
13:40, 17 September 2019
MaintBot
HMDB identifier normalization
85431
view
09:36, 15 May 2016
Egonw
Quick edit to datanode annotation or property
71689
view
19:42, 17 October 2013
MaintBot
Automated update of data sources
70570
view
14:52, 13 August 2013
Metalmephisto
Fixed Angiotensin ID
69295
view
18:41, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67023
view
09:55, 26 June 2013
Christine Chichester
Ontology Term : 'ACE inhibitor drug pathway' added !
57064
view
16:54, 20 January 2013
Egonw
Used "PubChem-compound"
41605
view
02:02, 2 March 2011
MaintBot
Removed redundant pathway information and comments
35047
view
09:36, 11 February 2010
Thomas
removed genmapp notes (invalid link)
35039
view
09:29, 11 February 2010
Thomas
Modified description
34334
view
22:16, 9 December 2009
MaintBot
Automatic update of empty xrefs
33572
view
09:47, 1 December 2009
MaintBot
Removed group label
30484
view
21:36, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ACE Inhibitor
Metabolite
ACE
GeneProduct
449567 (Entrez Gene)
AGT
GeneProduct
450104 (Entrez Gene)
AGTR1
GeneProduct
460762 (Entrez Gene)
AGTR2
GeneProduct
742608 (Entrez Gene)
Aldosterone
Metabolite
C01780 (Kegg Compound)
Angiotensin I
Metabolite
3081372 (PubChem)
Angiotensin II
Metabolite
HMDB01035 (HMDB)
BDKRB2
GeneProduct
467547 (Entrez Gene)
Bradykinin
Metabolite
HMDB04246 (HMDB)
KNG1
GeneProduct
460916 (Entrez Gene)
NOS3
GeneProduct
REN
GeneProduct
469651 (Entrez Gene)
Annotated Interactions
No annotated interactions
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No annotated interactions