Metapathway biotransformation (Bos taurus)
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Glucuronidation
Reduction
Hydrolysis
N-acetyltransferases
Glutathione synthetase
Glutathione transferases
Oxidation
Electrophiles
Nucleophiles
Amino acid conjugation
Aldo-keto reductases
Methyltransferases
Cytochrome P450
Glutathione conjugation
Flavin monooxygenases
Sulfotransferases
Methylation
Sulfation
Acetylation
Glucuronosyltransferases
Glutathione reductase
Amino acid acyl transferases
Glutathione peroxidases
Epoxide hydrolases
NP_001076882.1
FMO3
ARY1_BOVIN
A6H748_BOVIN
G3ST1_BOVIN
TPMT_BOVIN
CYP2C8
IPI00713683.4
ST1A1_BOVIN
IPI00710606.2
IPI00694081.4
NM_001075173.1
HS6ST2
NP_001029801.1
Glucuronosyltransferase
CYP3A5
IPI00716297.1
GSTM2
IPI00906608.1
IPI00709424.4
SULT1C4
GSTA4_BOVIN
NP_001092474.1
UGT1A7
IPI00905203.2
IPI00708458.2
IPI00705153.2
LOC515352
CYP27B1
CYP11B2
UGT1A9
NAT8
SULT2A1
MGST3_BOVIN
CP2E1_BOVIN
CYP2C18
GLYATL1
Glutathione transferase
Xenobiotic substrate
CYP450
UGT1A3
IPI00903985.1
IPI00697335.1
IPI00693008.2
CYP2C19
N-acetyltransferase
CYP21A2
NP_777187.1
Substrate-SG
GSTA3
NP_001095558.1
CYP11B1
NP_001071381.1
ST1A1_BOVIN
NP_001075096.1
IPI00699039.4
Substrate-OH
IPI00726067.3
NP_001094774.1
Methyltransferase
IPI00716958.3
GPX2
Aldo-keto reductase
CYP4F22
GSTA1
NP_001096716.1
GPX3_BOVIN
GSTM4
AKR7A3
UGT2B17
ARY1_BOVIN
ST1E1_BOVIN
CYP17A1
UGT1A10
NP_001071429.1
GPX4_BOVIN
IPI00702562.3
AKR1B1
NP_001069607.1
NP_001040025.1
Substrate-Ac
AKR7A2
NP_001093836.1
ST1B1_BOVIN
CYP2C9
COMT_BOVIN
IPI00698655.1
CYP4F8
G3ST4_BOVIN
AKR1C3
ST1A1_BOVIN
Substrate-CH3
NP_001069683.1
UGT2B4
GSTT2B
Substrate-Aa
CYP2A7
GSTT1
NP_001069613.1
XR_027890.2
KCAB2_BOVIN
GSTM5
NP_001020506.1
AKR1C1
GSHB_BOVIN
CYP2D6
NP_001092408.1
IPI00704129.5
UGT1A1
NP_001092414.1
GSTA5
UGT2B15
NP_001095549.1
NAT13_BOVIN
MGST1_BOVIN
NP_001073084.1
IPI00688142.3
CYP3A4
NP_001069154.1
HNMT_BOVIN
CYP3A7
NP_001069670.1
CYP4Z1
NNMT
GSTA2
UGT2B11
Q95KN3_BOVIN
Substrate=O
Flavin monooxygenase
UGT1A4
NP_001029545.1
AKR1C4
NP_001091480.1
GSTT2
UGT2B28
CP51A_BOVIN
ST1A1_BOVIN
IPI00689284.1
LOC614317
A6QPJ8_BOVIN
A9CSS1_BOVIN
IPI00709378.3
CP11A_BOVIN
Amino acid acyltransferase
IPI00700522.1
HS3ST4
UGT2A2
NP_001091500.1
NP_001069590.1
CHST8
IPI00695412.4
AKR1C2
NAT14_BOVIN
GSTP1_BOVIN
NP_001069735.1
UGT2A1
IPI00688083.3
Substrate-NH2
Substrate-Gl
GSTCD_BOVIN
UGT1A5
NP_001069002.1
IPI00692810.3
IPI00686912.3
CYP3A43
CYP2A13
CYP2A6
HS3ST3B1
CYP2F1
IPI00693768.3
CYP4F11
IPI00705496.1
CYP4F2
SULT2B1
Sulfotransferase
IPI00904186.1
IPI00695153.3
Substrate-SH
NP_001068630.1
NP_001069986.1
UGT2B7
HS3ST3A1
UGT1A6
CP20A_BOVIN
IPI00687876.3
GSTO1
GLYAT
CHST9
CYP46A1
NP_001077117.1
CHST14
CP2U1_BOVIN
IPI00698855.3
IPI00701497.5
Substrate-O-R
GPX1_BOVIN
IPI00693008.2
CYP2J2
AK1A1_BOVIN
CYP4F12
SULT1C2
G3ST3_BOVIN
NDST2_BOVIN
GSTM1
CYP19A1
MGST2_BOVIN
KCAB1_BOVIN
IPI00906116.1
Substrate-SO3H
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP702(r29945)
with a 58% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
80841
view
15:28, 30 June 2015
Mkutmon
homology conversion
70171
view
00:39, 13 July 2013
AlexanderPico
Modified title
63459
view
17:18, 10 May 2013
MaintBot
Updated to 2013 gpml schema
58827
view
23:19, 20 February 2013
MaintBot
Updated Ensembl and UniProt data source
53460
view
18:40, 7 November 2012
Andra
Added missing Entrez Gene Id's after RDF Tidy
40594
view
19:33, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33831
view
00:29, 9 December 2009
MaintBot
Automatic update of empty xrefs
33196
view
18:19, 5 November 2009
Khanspers
Modified categories
32487
view
12:45, 17 August 2009
MaintBot
Fixed text labels
32182
view
12:32, 15 August 2009
MaintBot
Fixed text labels
31652
view
11:37, 14 August 2009
MaintBot
Fixed group labels
31185
view
19:28, 13 August 2009
MaintBot
Fixed text labels
30575
view
22:07, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
A6H748_BOVIN
GeneProduct
ENSBTAG00000000085 (Ensembl Cow)
A6QPJ8_BOVIN
GeneProduct
ENSBTAG00000021118 (Ensembl Cow)
A9CSS1_BOVIN
GeneProduct
ENSBTAG00000010531 (Ensembl Cow)
AK1A1_BOVIN
GeneProduct
ENSBTAG00000000497 (Ensembl Cow)
AKR1B1
GeneProduct
317748 (Entrez Gene)
AKR1C1
GeneProduct
AKR1C2
GeneProduct
AKR1C3
GeneProduct
782884 (Entrez Gene)
AKR1C4
GeneProduct
282138 (Entrez Gene)
AKR7A2
GeneProduct
511996 (Entrez Gene)
AKR7A3
GeneProduct
788425 (Entrez Gene)
ARY1_BOVIN
GeneProduct
ENSBTAG00000016473 (Ensembl Cow)
Aldo-keto reductase
GeneProduct
Amino acid acyltransferase
GeneProduct
CHST14
GeneProduct
511245 (Entrez Gene)
CHST8
GeneProduct
100271926 (Entrez Gene)
CHST9
GeneProduct
525909 (Entrez Gene)
COMT_BOVIN
GeneProduct
ENSBTAG00000019516 (Ensembl Cow)
CP11A_BOVIN
GeneProduct
ENSBTAG00000006934 (Ensembl Cow)
CP20A_BOVIN
GeneProduct
ENSBTAG00000000851 (Ensembl Cow)
CP2E1_BOVIN
GeneProduct
ENSBTAG00000018365 (Ensembl Cow)
CP2U1_BOVIN
GeneProduct
ENSBTAG00000012972 (Ensembl Cow)
CP51A_BOVIN
GeneProduct
ENSBTAG00000001992 (Ensembl Cow)
CYP11B1
GeneProduct
282422 (Entrez Gene)
CYP11B2
GeneProduct
282423 (Entrez Gene)
CYP17A1
GeneProduct
782561 (Entrez Gene)
CYP19A1
GeneProduct
281740 (Entrez Gene)
CYP21A2
GeneProduct
282425 (Entrez Gene)
CYP27B1
GeneProduct
ENSBTAG00000016906 (Ensembl Cow)
CYP2A13
GeneProduct
CYP2A6
GeneProduct
CYP2A7
GeneProduct
CYP2C18
GeneProduct
535243 (Entrez Gene)
CYP2C19
GeneProduct
510380 (Entrez Gene)
CYP2C8
GeneProduct
CYP2C9
GeneProduct
CYP2D6
GeneProduct
282211 (Entrez Gene)
CYP2F1
GeneProduct
CYP2J2
GeneProduct
521656 (Entrez Gene)
CYP3A43
GeneProduct
CYP3A4
GeneProduct
507988 (Entrez Gene)
CYP3A5
GeneProduct
526682 (Entrez Gene)
CYP3A7
GeneProduct
CYP450
GeneProduct
CYP46A1
GeneProduct
506438 (Entrez Gene)
CYP4F11
GeneProduct
CYP4F12
GeneProduct
CYP4F22
GeneProduct
CYP4F2
GeneProduct
507615 (Entrez Gene)
CYP4F8
GeneProduct
CYP4Z1
GeneProduct
FMO3
GeneProduct
281167 (Entrez Gene)
Flavin monooxygenase
GeneProduct
G3ST1_BOVIN
GeneProduct
ENSBTAG00000014232 (Ensembl Cow)
G3ST3_BOVIN
GeneProduct
ENSBTAG00000002772 (Ensembl Cow)
G3ST4_BOVIN
GeneProduct
ENSBTAG00000015017 (Ensembl Cow)
GLYAT
GeneProduct
281787 (Entrez Gene)
GLYATL1
GeneProduct
GPX1_BOVIN
GeneProduct
ENSBTAG00000004274 (Ensembl Cow)
GPX2
GeneProduct
533088 (Entrez Gene)
GPX3_BOVIN
GeneProduct
ENSBTAG00000043553 (Ensembl Cow)
GPX4_BOVIN
GeneProduct
ENSBTAG00000020778 (Ensembl Cow)
GSHB_BOVIN
GeneProduct
ENSBTAG00000003504 (Ensembl Cow)
GSTA1
GeneProduct
777644 (Entrez Gene)
GSTA2
GeneProduct
GSTA3
GeneProduct
768055 (Entrez Gene)
GSTA4_BOVIN
GeneProduct
ENSBTAG00000004288 (Ensembl Cow)
GSTA5
GeneProduct
521685 (Entrez Gene)
GSTCD_BOVIN
GeneProduct
ENSBTAG00000013927 (Ensembl Cow)
GSTM1
GeneProduct
783879 (Entrez Gene)
GSTM2
GeneProduct
615537 (Entrez Gene)
GSTM4
GeneProduct
GSTM5
GeneProduct
GSTO1
GeneProduct
785216 (Entrez Gene)
GSTP1_BOVIN
GeneProduct
ENSBTAG00000003548 (Ensembl Cow)
GSTT1
GeneProduct
517724 (Entrez Gene)
GSTT2
GeneProduct
GSTT2B
GeneProduct
Glucuronosyltransferase
GeneProduct
Glutathione transferase
GeneProduct
HNMT_BOVIN
GeneProduct
ENSBTAG00000014432 (Ensembl Cow)
HS3ST3A1
GeneProduct
521959 (Entrez Gene)
HS3ST3B1
GeneProduct
617069 (Entrez Gene)
HS3ST4
GeneProduct
HS6ST2
GeneProduct
517768 (Entrez Gene)
IPI00686912.3
GeneProduct
ENSBTAG00000012998 (Ensembl Cow)
IPI00687876.3
GeneProduct
ENSBTAG00000001144 (Ensembl Cow)
IPI00688083.3
GeneProduct
ENSBTAG00000009093 (Ensembl Cow)
IPI00688142.3
GeneProduct
ENSBTAG00000006157 (Ensembl Cow)
IPI00689284.1
GeneProduct
ENSBTAG00000002803 (Ensembl Cow)
IPI00692810.3
GeneProduct
ENSBTAG00000001658 (Ensembl Cow)
IPI00693008.2
GeneProduct
ENSBTAG00000040000 (Ensembl Cow)
IPI00693768.3
GeneProduct
ENSBTAG00000038369 (Ensembl Cow)
IPI00694081.4
GeneProduct
ENSBTAG00000010644 (Ensembl Cow)
IPI00695153.3
GeneProduct
ENSBTAG00000001448 (Ensembl Cow)
IPI00695412.4
GeneProduct
ENSBTAG00000015647 (Ensembl Cow)
IPI00697335.1
GeneProduct
ENSBTAG00000011014 (Ensembl Cow)
IPI00698655.1
GeneProduct
ENSBTAG00000005287 (Ensembl Cow)
IPI00698855.3
GeneProduct
ENSBTAG00000025760 (Ensembl Cow)
IPI00699039.4
GeneProduct
ENSBTAG00000017595 (Ensembl Cow)
IPI00700522.1
GeneProduct
ENSBTAG00000012212 (Ensembl Cow)
IPI00701497.5
GeneProduct
ENSBTAG00000017701 (Ensembl Cow)
IPI00702562.3
GeneProduct
ENSBTAG00000008707 (Ensembl Cow)
IPI00704129.5
GeneProduct
ENSBTAG00000039319 (Ensembl Cow)
IPI00705153.2
GeneProduct
ENSBTAG00000016685 (Ensembl Cow)
IPI00705496.1
GeneProduct
ENSBTAG00000021408 (Ensembl Cow)
IPI00708458.2
GeneProduct
ENSBTAG00000017391 (Ensembl Cow)
IPI00709378.3
GeneProduct
ENSBTAG00000001692 (Ensembl Cow)
IPI00709424.4
GeneProduct
ENSBTAG00000001299 (Ensembl Cow)
IPI00710606.2
GeneProduct
ENSBTAG00000003131 (Ensembl Cow)
IPI00713683.4
GeneProduct
ENSBTAG00000002765 (Ensembl Cow)
IPI00716297.1
GeneProduct
ENSBTAG00000019249 (Ensembl Cow)
IPI00716958.3
GeneProduct
ENSBTAG00000040290 (Ensembl Cow)
IPI00726067.3
GeneProduct
ENSBTAG00000039065 (Ensembl Cow)
IPI00903985.1
GeneProduct
ENSBTAG00000007654 (Ensembl Cow)
IPI00904186.1
GeneProduct
ENSBTAG00000039973 (Ensembl Cow)
IPI00905203.2
GeneProduct
ENSBTAG00000038275 (Ensembl Cow)
IPI00906116.1
GeneProduct
ENSBTAG00000038084 (Ensembl Cow)
IPI00906608.1
GeneProduct
ENSBTAG00000011584 (Ensembl Cow)
KCAB1_BOVIN
GeneProduct
ENSBTAG00000018465 (Ensembl Cow)
KCAB2_BOVIN
GeneProduct
ENSBTAG00000008125 (Ensembl Cow)
LOC515352
GeneProduct
ENSBTAG00000030847 (Ensembl Cow)
LOC614317
GeneProduct
ENSBTAG00000031364 (Ensembl Cow)
MGST1_BOVIN
GeneProduct
ENSBTAG00000008541 (Ensembl Cow)
MGST2_BOVIN
GeneProduct
ENSBTAG00000021779 (Ensembl Cow)
MGST3_BOVIN
GeneProduct
ENSBTAG00000010265 (Ensembl Cow)
Methyltransferase
GeneProduct
N-acetyltransferase
GeneProduct
NAT13_BOVIN
GeneProduct
ENSBTAG00000007784 (Ensembl Cow)
NAT14_BOVIN
GeneProduct
ENSBTAG00000019051 (Ensembl Cow)
NAT8
GeneProduct
NDST2_BOVIN
GeneProduct
ENSBTAG00000012664 (Ensembl Cow)
NM_001075173.1
GeneProduct
ENSBTAG00000003871 (Ensembl Cow)
NNMT
GeneProduct
NP_001020506.1
GeneProduct
ENSBTAG00000021987 (Ensembl Cow)
NP_001029545.1
GeneProduct
ENSBTAG00000021263 (Ensembl Cow)
NP_001029801.1
GeneProduct
ENSBTAG00000000140 (Ensembl Cow)
NP_001040025.1
GeneProduct
ENSBTAG00000001842 (Ensembl Cow)
NP_001068630.1
GeneProduct
ENSBTAG00000002974 (Ensembl Cow)
NP_001069002.1
GeneProduct
ENSBTAG00000015241 (Ensembl Cow)
NP_001069154.1
GeneProduct
ENSBTAG00000002706 (Ensembl Cow)
NP_001069590.1
GeneProduct
ENSBTAG00000007449 (Ensembl Cow)
NP_001069607.1
GeneProduct
ENSBTAG00000034106 (Ensembl Cow)
NP_001069613.1
GeneProduct
ENSBTAG00000016968 (Ensembl Cow)
NP_001069670.1
GeneProduct
ENSBTAG00000011976 (Ensembl Cow)
NP_001069683.1
GeneProduct
ENSBTAG00000000188 (Ensembl Cow)
NP_001069735.1
GeneProduct
ENSBTAG00000010419 (Ensembl Cow)
NP_001069986.1
GeneProduct
ENSBTAG00000006273 (Ensembl Cow)
NP_001071381.1
GeneProduct
ENSBTAG00000020898 (Ensembl Cow)
NP_001071429.1
GeneProduct
ENSBTAG00000007316 (Ensembl Cow)
NP_001073084.1
GeneProduct
ENSBTAG00000009839 (Ensembl Cow)
NP_001075096.1
GeneProduct
ENSBTAG00000014940 (Ensembl Cow)
NP_001076882.1
GeneProduct
ENSBTAG00000013489 (Ensembl Cow)
NP_001077117.1
GeneProduct
ENSBTAG00000003721 (Ensembl Cow)
NP_001091480.1
GeneProduct
ENSBTAG00000004328 (Ensembl Cow)
NP_001091500.1
GeneProduct
ENSBTAG00000016747 (Ensembl Cow)
NP_001092408.1
GeneProduct
ENSBTAG00000003632 (Ensembl Cow)
NP_001092414.1
GeneProduct
ENSBTAG00000004040 (Ensembl Cow)
NP_001092474.1
GeneProduct
ENSBTAG00000003073 (Ensembl Cow)
NP_001093836.1
GeneProduct
ENSBTAG00000018240 (Ensembl Cow)
NP_001094774.1
GeneProduct
ENSBTAG00000010841 (Ensembl Cow)
NP_001095549.1
GeneProduct
ENSBTAG00000008778 (Ensembl Cow)
NP_001095558.1
GeneProduct
ENSBTAG00000001582 (Ensembl Cow)
NP_001096716.1
GeneProduct
ENSBTAG00000011387 (Ensembl Cow)
NP_777187.1
GeneProduct
ENSBTAG00000026181 (Ensembl Cow)
Q95KN3_BOVIN
GeneProduct
ENSBTAG00000001021 (Ensembl Cow)
ST1A1_BOVIN
GeneProduct
ENSBTAG00000008635 (Ensembl Cow)
ST1B1_BOVIN
GeneProduct
ENSBTAG00000001249 (Ensembl Cow)
ST1E1_BOVIN
GeneProduct
ENSBTAG00000011952 (Ensembl Cow)
SULT1C2
GeneProduct
783020 (Entrez Gene)
SULT1C4
GeneProduct
537919 (Entrez Gene)
SULT2A1
GeneProduct
533560 (Entrez Gene)
SULT2B1
GeneProduct
531192 (Entrez Gene)
Substrate-Aa
Metabolite
Substrate-Ac
Metabolite
Substrate-CH3
Metabolite
Substrate-Gl
Metabolite
Substrate-NH2
Metabolite
Substrate-O-R
Metabolite
Substrate-OH
Metabolite
Substrate-SG
Metabolite
Substrate-SH
Metabolite
Substrate-SO3H
Metabolite
Substrate=O
Metabolite
Sulfotransferase
GeneProduct
TPMT_BOVIN
GeneProduct
ENSBTAG00000019300 (Ensembl Cow)
UGT1A10
GeneProduct
UGT1A1
GeneProduct
751790 (Entrez Gene)
UGT1A3
GeneProduct
UGT1A4
GeneProduct
UGT1A5
GeneProduct
UGT1A6
GeneProduct
286792 (Entrez Gene)
UGT1A7
GeneProduct
UGT1A9
GeneProduct
UGT2A1
GeneProduct
UGT2A2
GeneProduct
UGT2B11
GeneProduct
100138004 (Entrez Gene)
UGT2B15
GeneProduct
540544 (Entrez Gene)
UGT2B17
GeneProduct
540615 (Entrez Gene)
UGT2B28
GeneProduct
UGT2B4
GeneProduct
615303 (Entrez Gene)
UGT2B7
GeneProduct
XR_027890.2
GeneProduct
ENSBTAG00000007115 (Ensembl Cow)
Xenobiotic substrate
Metabolite
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions