Heme biosynthesis (Pan troglodytes)

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Fe2+H+delta-aminolevulinateBlack - reactantsprotoporphyrinogen IXsuccinyl-CoA + glycinedelta-aminolevulinateRed - side productsrate limiting stepCPOXO2protoporphyrin IXO2ALADH2OCO2NH3FECHH2OPPOXH2O2UROShydroxymethylbilaneCO2ALAS1CO2URODporphobilinogenuroporphyrinogen IIIHMBSprotohemecoproporphyrinogen IIICoAALAS2H2OPorphobilinogen


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP561(r21860) with a 60% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
117403view10:36, 21 May 2021EweitzModified title
106914view13:38, 17 September 2019MaintBotHMDB identifier normalization
89924view13:34, 6 October 2016MkutmonModified description
88639view14:51, 12 August 2016JmeliusOntology Term : 'heme biosynthetic pathway' added !
71958view23:27, 23 October 2013MaintBotremoved data source from nodes without identifier
69997view22:33, 11 July 2013MaintBotupdated to 2013 schema
41533view01:57, 2 March 2011MaintBotRemoved redundant pathway information and comments
35291view22:53, 11 February 2010Mills42Modified description
34269view21:53, 9 December 2009MaintBotAutomatic update of empty xrefs
33518view15:20, 30 November 2009MaintBotRemoved group label
30417view21:15, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ALADGeneProduct464675 (Entrez Gene)
ALAS1GeneProduct460416 (Entrez Gene)
ALAS2GeneProduct473626 (Entrez Gene)
CO2MetaboliteHMDB01967 (HMDB)
CPOXGeneProduct460544 (Entrez Gene)
CoAMetaboliteHMDB01423 (HMDB)
FECHGeneProduct455437 (Entrez Gene)
H2O2MetaboliteHMDB03125 (HMDB)
H2OMetaboliteHMDB02111 (HMDB)
HMBSGeneProduct744366 (Entrez Gene)
NH3MetaboliteHMDB00051 (HMDB)
O2MetaboliteHMDB01377 (HMDB)
PPOXGeneProduct457450 (Entrez Gene)
PorphobilinogenMetaboliteHMDB00245 (HMDB)
URODGeneProduct456541 (Entrez Gene)
UROSGeneProduct450813 (Entrez Gene)
coproporphyrinogen IIIMetabolite
hydroxymethylbilaneMetabolite
porphobilinogenMetabolite
protohemeMetabolite
protoporphyrin IXMetabolite
uroporphyrinogen IIIMetabolite

Annotated Interactions

No annotated interactions
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