Insulin Signaling (Pan troglodytes)
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1
Vesicular Trafficking
p90 Rsk Kinases
Ras-MAPK Signaling
PI 3-Kinase
Translation Regulation
Metabolic Regulation
Glucose Transport
Tor Signaling
PDK/Akt Signaling
Modulators of Insulin Action
p70 S6 Kinases
Insulin Receptor Substrates
Transcriptional Regulators & Immediate Early Genes
MEK/MAP Kinases
HRAS
IRS1
MAP3K1
MAP4K3
JUN
PIK3C3
PPP1R3A
MAP3K2
MAP3K7
KIF3A
SH2B2
EIF4E
SLC2A4
MYO1C
RAC2
GYS1
INPPL1
IRS4
RRAD
MAP4K5
SHC1
PRKAA2
PRKCI
STX4A
RPS6KA3
MAPK11
MAPK1
MAP3K11
INPP4A
MAP4K2
FOS
GAB1
MAP3K10
EHD2
PFKL
RPS6KA2
PDPK1
RHEB
MAPK6
PIK3CA
MAP3K6
TBC1D4
RAB4A
MAP3K8
RHOQ
MAP3K3
IKBKB
STXBP4
SGK2
PIK3R4
MAP2K4
MAP2K6
PTEN
LIPE
GRB2
VAMP2
ARF6
PRKCD
EIF4EBP1
SGK
MAPK10
PIK3R3
RPS6KA6
AKT1
MAPK4
FRAP1
SORBS1
PIK3R1
PIK3C2A
MINK1
RAF1
GRB14
RPS6KB2
MAPK3
MAPK8
TSC1
SGK3
SNAP25
PIK3CG
SOCS1
PRKCA
CAP1
ARF1
SOS2
ENPP1
MAP2K3
INSR
IRS2
STXBP2
KIF5B
STXBP1
MAPK7
CBL
CBLC
FLOT2
MAP4K4
SNAP23
MAP2K2
MAP3K5
MAP3K9
TRIB3
CRK
PIK3R2
SRF
MAP2K5
PRKCB1
PIK3C2G
GSK3A
RAC1
SLC2A1
MAPK12
GRB10
SOS1
XBP1
FLOT1
PIK3CD
SHC2
ELK1
RPS6KB1
PTPN11
MAPK9
MAP4K1
EHD1
FOXO1
PRKCQ
PRKCH
RHOXF2
CBLB
MAP3K14
RPS6KA1
AKT2
RHOJ
RAPGEF1
PRKCZ
MAP3K12
SHC3
MAP3K13
MAPK13
IGF1R
PSCD3
MAP2K1
PFKM
EGR1
PRKAA1
FOXO3A
PTPN1
MAP2K7
RPS6KA4
PTPRF
MAPK14
TSC2
RPS6KA5
PIK3CB
SNX26
GSK3B
MAP3K4
GYS2
STXBP3
GYG1
SOCS3
MAPK8
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP481(r28132)
with a 72% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Bevan P; ''Insulin signalling.''; J Cell Sci, 2001
PubMed
Europe PMC
Scholia
Quon MJ, Campfield LA; ''A mathematical model and computer simulation study of insulin sensitive glucose transporter regulation.''; J Theor Biol, 1991
PubMed
Europe PMC
Scholia
Saltiel AR, Kahn CR; ''Insulin signalling and the regulation of glucose and lipid metabolism.''; Nature, 2001
PubMed
Europe PMC
Scholia
History
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Revision
Action
Time
User
Comment
69319
view
18:44, 8 July 2013
MaintBot
Updated to 2013 gpml schema
48148
view
18:41, 9 May 2012
MaintBot
Updating from human to fix xrefs
41629
view
02:03, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34356
view
22:24, 9 December 2009
MaintBot
Automatic update of empty xrefs
33517
view
15:19, 30 November 2009
MaintBot
Removed group label
31557
view
21:54, 13 August 2009
MaintBot
Fixed text labels
30416
view
21:15, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AKT1
GeneProduct
740898 (Entrez Gene)
AKT2
GeneProduct
456035 (Entrez Gene)
ARF1
GeneProduct
ARF6
GeneProduct
452892 (Entrez Gene)
CAP1
GeneProduct
746432 (Entrez Gene)
CBL
GeneProduct
451690 (Entrez Gene)
CBLB
GeneProduct
460566 (Entrez Gene)
CBLC
GeneProduct
CRK
GeneProduct
747142 (Entrez Gene)
EGR1
GeneProduct
462097 (Entrez Gene)
EHD1
GeneProduct
744047 (Entrez Gene)
EHD2
GeneProduct
456170 (Entrez Gene)
EIF4E
GeneProduct
468435 (Entrez Gene)
EIF4EBP1
GeneProduct
464114 (Entrez Gene)
ELK1
GeneProduct
ENPP1
GeneProduct
463002 (Entrez Gene)
FLOT1
GeneProduct
471961 (Entrez Gene)
FLOT2
GeneProduct
454537 (Entrez Gene)
FOS
GeneProduct
453047 (Entrez Gene)
FOXO1
GeneProduct
467352 (Entrez Gene)
FOXO3A
GeneProduct
FRAP1
GeneProduct
GAB1
GeneProduct
461516 (Entrez Gene)
GRB10
GeneProduct
463410 (Entrez Gene)
GRB14
GeneProduct
459695 (Entrez Gene)
GRB2
GeneProduct
737245 (Entrez Gene)
GSK3A
GeneProduct
456071 (Entrez Gene)
GSK3B
GeneProduct
470896 (Entrez Gene)
GYG1
GeneProduct
460765 (Entrez Gene)
GYS1
GeneProduct
456196 (Entrez Gene)
GYS2
GeneProduct
465336 (Entrez Gene)
HRAS
GeneProduct
466302 (Entrez Gene)
IGF1R
GeneProduct
453676 (Entrez Gene)
IKBKB
GeneProduct
472749 (Entrez Gene)
INPP4A
GeneProduct
470448 (Entrez Gene)
INPPL1
GeneProduct
451403 (Entrez Gene)
INSR
GeneProduct
455650 (Entrez Gene)
IRS1
GeneProduct
459985 (Entrez Gene)
IRS2
GeneProduct
452657 (Entrez Gene)
IRS4
GeneProduct
JUN
GeneProduct
456893 (Entrez Gene)
KIF3A
GeneProduct
450168 (Entrez Gene)
KIF5B
GeneProduct
450390 (Entrez Gene)
LIPE
GeneProduct
MAP2K1
GeneProduct
450188 (Entrez Gene)
MAP2K2
GeneProduct
456390 (Entrez Gene)
MAP2K3
GeneProduct
454515 (Entrez Gene)
MAP2K4
GeneProduct
455065 (Entrez Gene)
MAP2K5
GeneProduct
453532 (Entrez Gene)
MAP2K6
GeneProduct
468310 (Entrez Gene)
MAP2K7
GeneProduct
743199 (Entrez Gene)
MAP3K10
GeneProduct
MAP3K11
GeneProduct
451326 (Entrez Gene)
MAP3K12
GeneProduct
451940 (Entrez Gene)
MAP3K13
GeneProduct
737524 (Entrez Gene)
MAP3K14
GeneProduct
MAP3K1
GeneProduct
471543 (Entrez Gene)
MAP3K2
GeneProduct
736244 (Entrez Gene)
MAP3K3
GeneProduct
MAP3K4
GeneProduct
MAP3K5
GeneProduct
463023 (Entrez Gene)
MAP3K6
GeneProduct
456674 (Entrez Gene)
MAP3K7
GeneProduct
462888 (Entrez Gene)
MAP3K8
GeneProduct
450384 (Entrez Gene)
MAP3K9
GeneProduct
467498 (Entrez Gene)
MAP4K1
GeneProduct
748652 (Entrez Gene)
MAP4K2
GeneProduct
451301 (Entrez Gene)
MAP4K3
GeneProduct
459173 (Entrez Gene)
MAP4K4
GeneProduct
459459 (Entrez Gene)
MAP4K5
GeneProduct
467451 (Entrez Gene)
MAPK10
GeneProduct
461358 (Entrez Gene)
MAPK11
GeneProduct
MAPK12
GeneProduct
MAPK13
GeneProduct
462644 (Entrez Gene)
MAPK14
GeneProduct
450161 (Entrez Gene)
MAPK1
GeneProduct
458680 (Entrez Gene)
MAPK3
GeneProduct
454037 (Entrez Gene)
MAPK4
GeneProduct
MAPK6
GeneProduct
453439 (Entrez Gene)
MAPK7
GeneProduct
454499 (Entrez Gene)
MAPK8
GeneProduct
450445 (Entrez Gene)
MAPK9
GeneProduct
462336 (Entrez Gene)
MINK1
GeneProduct
454455 (Entrez Gene)
MYO1C
GeneProduct
750403 (Entrez Gene)
PDPK1
GeneProduct
PFKL
GeneProduct
458602 (Entrez Gene)
PFKM
GeneProduct
451863 (Entrez Gene)
PIK3C2A
GeneProduct
451052 (Entrez Gene)
PIK3C2G
GeneProduct
465321 (Entrez Gene)
PIK3C3
GeneProduct
455385 (Entrez Gene)
PIK3CA
GeneProduct
460858 (Entrez Gene)
PIK3CB
GeneProduct
471079 (Entrez Gene)
PIK3CD
GeneProduct
457922 (Entrez Gene)
PIK3CG
GeneProduct
463649 (Entrez Gene)
PIK3R1
GeneProduct
461836 (Entrez Gene)
PIK3R2
GeneProduct
455855 (Entrez Gene)
PIK3R3
GeneProduct
456565 (Entrez Gene)
PIK3R4
GeneProduct
460692 (Entrez Gene)
PPP1R3A
GeneProduct
463666 (Entrez Gene)
PRKAA1
GeneProduct
PRKAA2
GeneProduct
741802 (Entrez Gene)
PRKCA
GeneProduct
454832 (Entrez Gene)
PRKCB1
GeneProduct
PRKCD
GeneProduct
PRKCH
GeneProduct
746068 (Entrez Gene)
PRKCI
GeneProduct
450143 (Entrez Gene)
PRKCQ
GeneProduct
450288 (Entrez Gene)
PRKCZ
GeneProduct
743533 (Entrez Gene)
PSCD3
GeneProduct
PTEN
GeneProduct
466142 (Entrez Gene)
PTPN11
GeneProduct
748225 (Entrez Gene)
PTPN1
GeneProduct
469970 (Entrez Gene)
PTPRF
GeneProduct
456828 (Entrez Gene)
RAB4A
GeneProduct
RAC1
GeneProduct
RAC2
GeneProduct
742575 (Entrez Gene)
RAF1
GeneProduct
460182 (Entrez Gene)
RAPGEF1
GeneProduct
464812 (Entrez Gene)
RHEB
GeneProduct
463880 (Entrez Gene)
RHOJ
GeneProduct
452960 (Entrez Gene)
RHOQ
GeneProduct
740809 (Entrez Gene)
RHOXF2
GeneProduct
473763 (Entrez Gene)
RPS6KA1
GeneProduct
RPS6KA2
GeneProduct
RPS6KA3
GeneProduct
450110 (Entrez Gene)
RPS6KA4
GeneProduct
451715 (Entrez Gene)
RPS6KA5
GeneProduct
739162 (Entrez Gene)
RPS6KA6
GeneProduct
RPS6KB1
GeneProduct
468426 (Entrez Gene)
RPS6KB2
GeneProduct
746903 (Entrez Gene)
RRAD
GeneProduct
741038 (Entrez Gene)
SGK
GeneProduct
SGK2
GeneProduct
740699 (Entrez Gene)
SGK3
GeneProduct
464217 (Entrez Gene)
SH2B2
GeneProduct
741557 (Entrez Gene)
SHC1
GeneProduct
457351 (Entrez Gene)
SHC2
GeneProduct
SHC3
GeneProduct
450176 (Entrez Gene)
SLC2A1
GeneProduct
SLC2A4
GeneProduct
468443 (Entrez Gene)
SNAP23
GeneProduct
453365 (Entrez Gene)
SNAP25
GeneProduct
458096 (Entrez Gene)
SNX26
GeneProduct
748029 (Entrez Gene)
SOCS1
GeneProduct
737070 (Entrez Gene)
SOCS3
GeneProduct
454921 (Entrez Gene)
SORBS1
GeneProduct
450628 (Entrez Gene)
SOS1
GeneProduct
459171 (Entrez Gene)
SOS2
GeneProduct
452897 (Entrez Gene)
SRF
GeneProduct
462709 (Entrez Gene)
STX4A
GeneProduct
STXBP1
GeneProduct
STXBP2
GeneProduct
741963 (Entrez Gene)
STXBP3
GeneProduct
737947 (Entrez Gene)
STXBP4
GeneProduct
468411 (Entrez Gene)
TBC1D4
GeneProduct
467286 (Entrez Gene)
TRIB3
GeneProduct
745623 (Entrez Gene)
TSC1
GeneProduct
464818 (Entrez Gene)
TSC2
GeneProduct
468086 (Entrez Gene)
VAMP2
GeneProduct
747237 (Entrez Gene)
XBP1
GeneProduct
458735 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Bibliography
History
External references
DataNodes
Annotated Interactions
No annotated interactions