Eukaryotic transcription initiation (Mus musculus)
From WikiPathways
Revision as of 18:28, 10 December 2008 by
AlexanderPico
(
Talk
|
contribs
)
(
diff
)
←Older revision
|
Current revision
(
diff
) |
Newer revision→
(
diff
)
Jump to:
navigation
,
search
TFIID
5
RNA polymerase II
TFIIA
5
5
TFIIF
5
5
3
3
TATA
TFIIB
3
5
5
3
TFIIE
Gene Regulatory Proteins
(small stable RNAs)
TATA
dsDNA
(mRNA, snRNPs)
TFIIA
5
TFIIE
3
Steps 2) Association of TIFs and RNA polymerase
TFIIF
5
(large ribosomal RNAs)
3
Transcription Initiation Factors (TIFs)
(recognize surface DNA geometry)
RNA pol II
RNA polymerase I
3
Steps 5) RNA elongation with CDT phosphorylation
Steps 1) TBP binds TATA box
TFIID
Steps 4) Transcription elongation by NTPs
TATA
TFIIH
3
TFIIB
protein
TATA Box binding
cell growth
Steps 3) DNA melting by association with TFIIH
3
TFIIH
TFIIF
5
Primary RNA transcript
RNA polymerase III
Polr2c
Polr2a
Polr2b
Gtf2h1
Mnat1
Taf7
Rpo1-3
Gtf2a2
Gtf2f2
Ccnh
Gtf2h3
Taf9
Polr2e
Polr2k
Gtf2h2
Tbp
Polr2g
Polr2i
Cdk7
Polr2j
Rpo1-4
Rpo1-2
Polr3h
Ercc3
Polr3d
Taf13
Taf12
Ilk
Ercc2
Rpo1-1
Taf6
Gtf2h4
Gtf2e1
Polr3b
Polr3k
Polr3e
Polr2f
Gtf2b
Gtf2e2
Polr2h
Taf5
Description
No description
Comments
GenMAPP notes
Reference:
http://www.web-books.com/MoBio/Free/Ch4E.htm
GenMAPP remarks
right click for notes & references
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
Lee TI, Young RA; ''Regulation of gene expression by TBP-associated proteins.''; Genes Dev, 1998
PubMed
Europe PMC
Scholia
Lemon B, Tjian R; ''Orchestrated response: a symphony of transcription factors for gene control.''; Genes Dev, 2000
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
117881
view
10:21, 23 May 2021
Eweitz
Modified title
89957
view
18:07, 6 October 2016
Mkutmon
fix unconnected lines
69915
view
19:37, 11 July 2013
Mkutmon
fixed unconnected lines
69137
view
18:16, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67216
view
10:22, 26 June 2013
Christine Chichester
Ontology Term : 'transcription pathway' added !
41326
view
00:25, 2 March 2011
MaintBot
Removed redundant pathway information and comments
35533
view
14:04, 12 February 2010
Thomas
added literature
35522
view
13:53, 12 February 2010
Thomas
Modified description
34504
view
23:33, 16 December 2009
Khanspers
Added connectors
26591
view
18:28, 10 December 2008
AlexanderPico
21874
view
11:32, 14 November 2008
MaintBot
[[Pathway:Mus musculus:RNA transcription Reactome]] moved to [[Pathway:WP567]]: Moved to stable identifier
8368
view
13:46, 7 January 2008
MaintBot
[[Pathway:Mouse:RNA transcription Reactome]] moved to [[Pathway:Mus musculus:RNA transcription Reactome]]: Renaming species
7802
view
16:18, 18 December 2007
MaintBot
fixed category names
7287
view
12:41, 4 November 2007
MaintBot
Added categories to GPML
6489
view
22:19, 22 May 2007
Nsalomonis
gpml file for [[Mouse:RNA_transcription_Reactome]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Ccnh
GeneProduct
66671 (Entrez Gene)
Cdk7
GeneProduct
12572 (Entrez Gene)
Ercc2
GeneProduct
13871 (Entrez Gene)
Ercc3
GeneProduct
13872 (Entrez Gene)
Gtf2a2
GeneProduct
235459 (Entrez Gene)
Gtf2b
GeneProduct
229906 (Entrez Gene)
Gtf2e1
GeneProduct
74197 (Entrez Gene)
Gtf2e2
GeneProduct
68153 (Entrez Gene)
Gtf2f2
GeneProduct
68705 (Entrez Gene)
Gtf2h1
GeneProduct
14884 (Entrez Gene)
Gtf2h2
GeneProduct
23894 (Entrez Gene)
Gtf2h3
GeneProduct
209357 (Entrez Gene)
Gtf2h4
GeneProduct
14885 (Entrez Gene)
Ilk
GeneProduct
16202 (Entrez Gene)
Mnat1
GeneProduct
17420 (Entrez Gene)
Polr2a
GeneProduct
20020 (Entrez Gene)
Polr2b
GeneProduct
231329 (Entrez Gene)
Polr2c
GeneProduct
20021 (Entrez Gene)
Polr2e
GeneProduct
66420 (Entrez Gene)
Polr2f
GeneProduct
110812 (Entrez Gene)
Polr2g
GeneProduct
67710 (Entrez Gene)
Polr2h
GeneProduct
245841 (Entrez Gene)
Polr2i
GeneProduct
69920 (Entrez Gene)
Polr2j
GeneProduct
20022 (Entrez Gene)
Polr2k
GeneProduct
17749 (Entrez Gene)
Polr3b
GeneProduct
70428 (Entrez Gene)
Polr3d
GeneProduct
67065 (Entrez Gene)
Polr3e
GeneProduct
26939 (Entrez Gene)
Polr3h
GeneProduct
78929 (Entrez Gene)
Polr3k
GeneProduct
67005 (Entrez Gene)
Rpo1-1
GeneProduct
20016 (Entrez Gene)
Rpo1-2
GeneProduct
20017 (Entrez Gene)
Rpo1-3
GeneProduct
20018 (Entrez Gene)
Rpo1-4
GeneProduct
20019 (Entrez Gene)
Taf12
GeneProduct
66464 (Entrez Gene)
Taf13
GeneProduct
99730 (Entrez Gene)
Taf5
GeneProduct
226182 (Entrez Gene)
Taf6
GeneProduct
21343 (Entrez Gene)
Taf7
GeneProduct
24074 (Entrez Gene)
Taf9
GeneProduct
108143 (Entrez Gene)
Tbp
GeneProduct
21374 (Entrez Gene)
Annotated Interactions
No annotated interactions
Views
Pathway
Discussion
View source
Personal tools
Log in / create account
search
Help
About us
Contact us
Report a bug
How to cite
Quality control
Development
Publications using WikiPathways
Curation Events
Download
Download files
Other file formats
Web service API
WikiPathways RDF
Embed code
Activity
Browse pathways
Recent changes
New releases
New pathways
Edit pathways
Create pathway
Statistics
Tools
PathwayWidget
Pathway Finder
Software tools
Community Portals
Help on Portals
Adverse Outcome Pathways
Inherited Metabolic Disorders
CIRM
COVID-19
CPTAC
Diseases
ExRNA
Lipids
Micronutrients
Nanomaterials
NetPath
Plants
Rare Disease
Renal Genomics
Reactome
Skeletal Dysplasia
WormBase
Toolbox
What links here
Related changes
Upload file
Special pages
Printable version
Permanent link
Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
Ontology Terms
Bibliography
History
External references
DataNodes
Annotated Interactions
No annotated interactions