Cholesterol biosynthesis (Bos taurus)
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1-7
Fatty Acid Degradation
farnesyl pyrophosphate
LSS
Mevalonic acid 5-pyrophosphate
PMVK
Dimethylallylpyrophosphate
SC5DL
HMG-CoA
FDPS
SQLE
Acetyl-CoA
isopentenyl pyrophosphate
Geranyl-PP
FDPS
MVD
DHCR7
Mevalonic acid
HMGCR
CYP51
Squalene
Mevalonic acid-5P
Cholesterol
7-Dehydrocholesterol
Lanosterin
MVK
(S)-2,3-Epoxysqualene
NSDHL
SC4MOL
HMGCS1
IDI1
Lathosterol
FDFT1
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP197(r21093)
with a 82% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
118367
view
13:46, 27 May 2021
Eweitz
Ontology Term : 'cholesterol biosynthetic pathway' added !
117487
view
11:01, 21 May 2021
Eweitz
Modified title
105958
view
11:48, 16 August 2019
MaintBot
HMDB identifier normalization
101765
view
13:47, 7 November 2018
Egonw
Replaced a wrong CAS number of with right ChEBI identifier.
85039
view
07:05, 10 April 2016
Egonw
Reverted to version '15:24, 30 June 2015' by
Egonw
85038
view
03:21, 10 April 2016
Khanspers
Quick edit to datanode annotation or property
80735
view
15:24, 30 June 2015
Mkutmon
homology conversion
71427
view
19:03, 17 October 2013
MaintBot
Automated update of data sources
67110
view
10:07, 26 June 2013
Christine Chichester
Ontology Term : 'cholesterol biosynthetic pathway' added !
63450
view
17:14, 10 May 2013
MaintBot
Updated to 2013 gpml schema
40584
view
19:33, 1 March 2011
MaintBot
Removed redundant pathway information and comments
35152
view
14:22, 11 February 2010
Thomas
Modified description
35151
view
14:21, 11 February 2010
Thomas
moved literature from genmapp comments to bibliography
33822
view
00:25, 9 December 2009
MaintBot
Automatic update of empty xrefs
31703
view
11:50, 14 August 2009
MaintBot
Fixed group labels
30639
view
22:29, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
(S)-2,3-Epoxysqualene
Metabolite
9029-62-3 (CAS)
7-Dehydrocholesterol
Metabolite
434-16-2 (CAS)
Acetyl-CoA
Metabolite
CYP51
GeneProduct
505060 (Entrez Gene)
Cholesterol
Metabolite
57-88-5 (CAS)
DHCR7
GeneProduct
514745 (Entrez Gene)
Dimethylallylpyrophosphate
Metabolite
358-72-5 (CAS)
FDFT1
GeneProduct
281767 (Entrez Gene)
FDPS
GeneProduct
281156 (Entrez Gene)
Geranyl-PP
Metabolite
6699-20-3 (CAS)
HMG-CoA
Metabolite
HMGCR
GeneProduct
407159 (Entrez Gene)
HMGCS1
GeneProduct
783184 (Entrez Gene)
IDI1
GeneProduct
514293 (Entrez Gene)
LSS
GeneProduct
615906 (Entrez Gene)
Lanosterin
Metabolite
79-63-0 (CAS)
Lathosterol
Metabolite
80-99-9 (CAS)
MVD
GeneProduct
509958 (Entrez Gene)
MVK
GeneProduct
505792 (Entrez Gene)
Mevalonic acid 5-pyrophosphate
Metabolite
1492-08-6 (CAS)
Mevalonic acid-5P
Metabolite
73566-35-5 (CAS)
Mevalonic acid
Metabolite
150-97-0 (CAS)
NSDHL
GeneProduct
616694 (Entrez Gene)
NAD(P) dependent steroid dehydrogenase-like
PMVK
GeneProduct
513533 (Entrez Gene)
SC4MOL
GeneProduct
504481 (Entrez Gene)
SC5DL
GeneProduct
525154 (Entrez Gene)
SQLE
GeneProduct
526535 (Entrez Gene)
Squalene
Metabolite
111-02-4 (CAS)
farnesyl pyrophosphate
Metabolite
13058-04-3 (CAS)
isopentenyl pyrophosphate
Metabolite
358-71-4 (CAS)
Annotated Interactions
No annotated interactions
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