Eicosanoid synthesis (Mus musculus)
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1
Prostaglandin E2
15-Hydroperoxy Eicosatetraenoic Acid
12-Hydroperoxy Eicosatetraenoic Acid
Cell Membrane
Thromboxane A3
6-Keto-Prostaglandin F2-alpha
Pla2g6
Ltc4s
PGD2 11-ketoreduc
Leukotriene D4
PGE2 9-ketoreduc
Ggt1
Leukotriene A4
Peroxidase?
Leukotriene B4
Prostaglandin F2a
Alox5ap
Prostaglandin H2
Thromboxane B2
15-HETE
Arachidonic acid
Alox8
Ptgis
Alox12
Alox15
Pla2g6
Leukotriene C4
Pnpla8
Ptges2
Pla2g2a
Prostaglandin D2
Tbxas1
5-HPETE
Leukotriene E4
Ptgs1
Prostaglandin I2
Ptgs2
Alox5ap
Ptges
Lta4h
Ptgds
5-HETE
Thromboxane A2
Alox5
Alox15
Peroxidase?
Peroxidase?
Alox5
12-HETE
Dpep1
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP167(r21031)
with a 70% conversion rate.
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Funk CD; ''Prostaglandins and leukotrienes: advances in eicosanoid biology.''; Science, 2001
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
117878
view
10:20, 23 May 2021
Eweitz
Modified title
106877
view
13:35, 17 September 2019
MaintBot
HMDB identifier normalization
89525
view
11:03, 16 September 2016
Mkutmon
ontology tag fix
89477
view
13:39, 15 September 2016
Mkutmon
remove space from ontology term id
71719
view
20:16, 17 October 2013
MaintBot
Automated update of data sources
71313
view
17:15, 17 October 2013
MaintBot
Automated update of data sources
69076
view
18:09, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67186
view
10:18, 26 June 2013
Christine Chichester
Ontology Term : 'eicosanoid biosynthetic pathway' added !
62829
view
04:44, 3 May 2013
MaintBot
Updated UniProt data source
41263
view
00:21, 2 March 2011
MaintBot
Removed redundant pathway information and comments
35469
view
12:08, 12 February 2010
Thomas
Modified description
35468
view
12:08, 12 February 2010
Thomas
added literature
34376
view
22:44, 9 December 2009
MaintBot
Automatic update of empty xrefs
32690
view
23:04, 31 August 2009
Khanspers
updated xrefs
32047
view
13:30, 14 August 2009
MaintBot
Fixed group labels
30816
view
23:56, 29 July 2009
MaintBot
Converted from Homo sapiens
21349
view
11:31, 14 November 2008
MaintBot
[[Pathway:Mus musculus:Eicosanoid Synthesis]] moved to [[Pathway:WP318]]: Moved to stable identifier
8004
view
13:46, 7 January 2008
MaintBot
[[Pathway:Mouse:Eicosanoid Synthesis]] moved to [[Pathway:Mus musculus:Eicosanoid Synthesis]]: Renaming species
7625
view
16:05, 18 December 2007
MaintBot
fixed category names
7338
view
12:42, 4 November 2007
MaintBot
Added categories to GPML
6434
view
22:18, 22 May 2007
A.Kwa
gpml file for [[Mouse:Eicosanoid_Synthesis]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
12-HETE
Metabolite
15-HETE
Metabolite
5-HETE
Metabolite
70608-72-9 (CAS)
5-HPETE
Metabolite
HMDB01193 (HMDB)
Alox12
GeneProduct
11684 (Entrez Gene)
Alox15
GeneProduct
11687 (Entrez Gene)
Alox5
GeneProduct
11689 (Entrez Gene)
Alox5ap
GeneProduct
11690 (Entrez Gene)
Alox8
GeneProduct
11688 (Entrez Gene)
Arachidonic acid
Metabolite
HMDB01043 (HMDB)
Dpep1
GeneProduct
13479 (Entrez Gene)
Ggt1
GeneProduct
14598 (Entrez Gene)
Leukotriene A4
Metabolite
HMDB01337 (HMDB)
Leukotriene B4
Metabolite
HMDB01085 (HMDB)
Leukotriene C4
Metabolite
HMDB01198 (HMDB)
Leukotriene D4
Metabolite
HMDB03080 (HMDB)
Leukotriene E4
Metabolite
HMDB02200 (HMDB)
Lta4h
GeneProduct
16993 (Entrez Gene)
Ltc4s
GeneProduct
17001 (Entrez Gene)
PGD2 11-ketoreduc
GeneProduct
PGE2 9-ketoreduc
GeneProduct
Peroxidase?
GeneProduct
Pla2g2a
GeneProduct
18780 (Entrez Gene)
Pla2g6
GeneProduct
53357 (Entrez Gene)
Pnpla8
GeneProduct
67452 (Entrez Gene)
Prostaglandin D2
Metabolite
HMDB01403 (HMDB)
Prostaglandin F2a
Metabolite
HMDB01139 (HMDB)
Prostaglandin H2
Metabolite
HMDB01381 (HMDB)
Prostaglandin I2
Metabolite
HMDB01335 (HMDB)
Ptgds
GeneProduct
19215 (Entrez Gene)
Ptges2
GeneProduct
96979 (Entrez Gene)
Ptges
GeneProduct
64292 (Entrez Gene)
Ptgis
GeneProduct
19223 (Entrez Gene)
Ptgs1
GeneProduct
19224 (Entrez Gene)
Ptgs2
GeneProduct
19225 (Entrez Gene)
Tbxas1
GeneProduct
21391 (Entrez Gene)
Thromboxane A2
Metabolite
HMDB01452 (HMDB)
Thromboxane B2
Metabolite
HMDB03252 (HMDB)
Annotated Interactions
No annotated interactions
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Discussion
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Try the New WikiPathways
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No annotated interactions