Electron transport chain (Bos taurus)

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IntermembraneSpaceComplex IVComplex IINADH-UbiquinoneOxidoreductaseComplex IIIF1 ComplexComplex VATP Synthase F0 ComplexComplex IC subunitbinds ATP Synthase betaAdenine NucleotideTranslocatorCytochrome COxidaseStalkUbiquinol-Cytochrome CReductaseAssemblySuccinate-UbiquinoneOxidoreductaseMatrixUncoupling ProteinNDUFS3COX1ATP6NDUFB3LOC100139115ND5NDUFV3NDUFB4H+ATP5G3NDUFC1SLC25A5NDUFB7NDUFA5NDUFA4NDUFB9H+ATP5LNDUFS5ND4NDUFB10SLC25A14UCP2ATP5G1FADH2NDUFAB1SDHBATP5A1NDUFS2NDUFV1NDUFS6NDUFB6COX4H+ATP5EUQCRBe-NDUFA7COX2COX7A2LATPIF1SDHCNDUFA8COX5BNDUFA3ATP5SUbiquinoneUQCRC1UQCRHO2NDUFB1NDUFA12ATP5G2H+COX3COX7A1ATP5DND3ATPNDUFB2NDUFB8NDUFB5UCRCFADCOX17SuccinateCOX5AATP5C1NDUFA1H+NDUFS4COX6A1H2OCOX7A2ND4LND2ATP5BCOX8ASDHDNDUFA9ATP5ONDUFV2e-COX7BNDUFA2COX7CUQCRUQCRFS1COX6CCOX11UQCRQCOX15NDUFS7LOC338087NDUFS8SDHASCO1UQCRC2ATP5F1ATP5He-COX6A2UCP3SLC25A27NDUFC2NDUFA10H+ATP5JH+NADHCOX7A3Cytochrome CNDUFA6ND1SLC25A4ATP8TCA CycleND6ATP5J2NDUFS1CYTBNAD+SLC25A6UCP1ATP5I


Description

An electron transport chain(ETC) couples a chemical reaction between an electron donor (such as NADH) and an electron acceptor (such as O2) to the transfer of H+ ions across a membrane, through a set of mediating biochemical reactions. These H+ ions are used to produce adenosine triphosphate (ATP), the main energy intermediate in living organisms, as they move back across the membrane.

In mitochondria, it is the conversion of oxygen to water, NADH to NAD+ and succinate to fumarate that drives the transfer of H+ ions.

Source: Wikipedia (wikipedia:Electron_transport_chain)

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP111(r20917) with a 68% conversion rate.

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Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
117502view11:04, 21 May 2021EweitzModified title
115320view09:10, 13 February 2021EgonwMade a pathway clickable
105988view11:51, 16 August 2019MaintBotHMDB identifier normalization
95788view14:40, 19 January 2018MkutmonHomology conversion update
86840view13:32, 13 July 2016Mkutmonontology tag fix
80879view15:29, 30 June 2015Mkutmonhomology conversion
71424view19:02, 17 October 2013MaintBotAutomated update of data sources
63445view17:13, 10 May 2013MaintBotUpdated to 2013 gpml schema
62711view23:19, 1 May 2013MaintBotUpdated UniProt data source
58282view18:45, 11 February 2013MaintBotOntology Term : 'electron transport chain pathway' added !
58251view23:00, 10 February 2013EgonwRemoved data source where no ID was given.
40579view19:33, 1 March 2011MaintBotRemoved redundant pathway information and comments
38662view13:56, 23 September 2010FerryJagersLinked TCA Cycle
35260view20:17, 11 February 2010AlexanderPicoModified description
33816view00:23, 9 December 2009MaintBotAutomatic update of empty xrefs
32484view12:44, 17 August 2009MaintBotFixed text labels
32180view12:32, 15 August 2009MaintBotFixed text labels
31649view11:36, 14 August 2009MaintBotFixed group labels
31182view19:27, 13 August 2009MaintBotFixed text labels
30571view22:06, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATP5A1GeneProduct282578 (Entrez Gene)
ATP5BGeneProduct327675 (Entrez Gene)
ATP5C1GeneProduct327668 (Entrez Gene)
ATP5DGeneProduct338081 (Entrez Gene)
ATP5EGeneProduct617230 (Entrez Gene)
ATP5F1GeneProduct282701 (Entrez Gene)
ATP5G1GeneProduct338053 (Entrez Gene)
ATP5G2GeneProduct790459 (Entrez Gene)
ATP5G3GeneProduct540176 (Entrez Gene)
ATP5HGeneProduct282710 (Entrez Gene)
ATP5IGeneProduct338040 (Entrez Gene)
ATP5J2GeneProduct506492 (Entrez Gene)
ATP5JGeneProduct282690 (Entrez Gene)
ATP5LGeneProduct515696 (Entrez Gene)
ATP5OGeneProduct281640 (Entrez Gene)
ATP5SGeneProduct493709 (Entrez Gene)
ATP6GeneProduct3283882 (Entrez Gene)
ATP8GeneProduct3283881 (Entrez Gene)
ATPMetaboliteC00002 (Kegg Compound)
ATPIF1GeneProduct327699 (Entrez Gene)
COX11GeneProduct510509 (Entrez Gene)
COX1GeneProduct3283879 (Entrez Gene)
COX15GeneProduct517811 (Entrez Gene)
COX17GeneProduct281708 (Entrez Gene)
COX2GeneProduct3283880 (Entrez Gene)
COX3GeneProduct3283883 (Entrez Gene)
COX4GeneProduct281090 (Entrez Gene)
COX5AGeneProduct444878 (Entrez Gene)
COX5BGeneProduct287012 (Entrez Gene)
COX6A1GeneProduct282199 (Entrez Gene)
COX6A2GeneProduct282200 (Entrez Gene)
COX6CGeneProduct782486 (Entrez Gene)
COX7A1GeneProduct338086 (Entrez Gene)
COX7A2GeneProduct327688 (Entrez Gene)
COX7A2LGeneProduct540225 (Entrez Gene)
COX7A3GeneProduct
COX7BGeneProduct327674 (Entrez Gene)
COX7CGeneProduct327718 (Entrez Gene)
COX8AGeneProduct281091 (Entrez Gene)
CYTBGeneProduct3283889 (Entrez Gene)
Cytochrome CMetaboliteC00524 (Kegg Compound)
FADMetaboliteC00016 (Kegg Compound)
FADH2MetaboliteC01352 (Kegg Compound)
H+MetaboliteHMDB01362 (HMDB)
H2OMetaboliteHMDB02111 (HMDB)
LOC100139115GeneProduct100139115 (Entrez Gene)
LOC338087GeneProduct338087 (Entrez Gene)
NAD+MetaboliteC00003 (Kegg Compound)
NADHMetaboliteC00004 (Kegg Compound)
ND1GeneProduct3283877 (Entrez Gene)
ND2GeneProduct3283878 (Entrez Gene)
ND3GeneProduct3283884 (Entrez Gene)
ND4GeneProduct3283886 (Entrez Gene)
ND4LGeneProduct3283885 (Entrez Gene)
ND5GeneProduct3283887 (Entrez Gene)
ND6GeneProduct3283888 (Entrez Gene)
NDUFA10GeneProduct338060 (Entrez Gene)
NDUFA12GeneProduct281742 (Entrez Gene)
NDUFA1GeneProduct781020 (Entrez Gene)
NDUFA2GeneProduct785629 (Entrez Gene)
NDUFA3GeneProduct338064 (Entrez Gene)
NDUFA4GeneProduct327704 (Entrez Gene)
NDUFA5GeneProduct327714 (Entrez Gene)
NDUFA6GeneProduct327670 (Entrez Gene)
NDUFA7GeneProduct338063 (Entrez Gene)
NDUFA8GeneProduct327710 (Entrez Gene)
NDUFA9GeneProduct404188 (Entrez Gene)
NDUFAB1GeneProduct327702 (Entrez Gene)
NDUFB10GeneProduct327701 (Entrez Gene)
NDUFB1GeneProduct327690 (Entrez Gene)
NDUFB2GeneProduct327713 (Entrez Gene)
NDUFB3GeneProduct338073 (Entrez Gene)
NDUFB4GeneProduct617694 (Entrez Gene)
NDUFB5GeneProduct338061 (Entrez Gene)
NDUFB6GeneProduct327665 (Entrez Gene)
NDUFB7GeneProduct338065 (Entrez Gene)
NDUFB8GeneProduct282517 (Entrez Gene)
NDUFB9GeneProduct327660 (Entrez Gene)
NDUFC1GeneProduct282289 (Entrez Gene)
NDUFC2GeneProduct338046 (Entrez Gene)
NDUFS1GeneProduct288380 (Entrez Gene)
NDUFS2GeneProduct327697 (Entrez Gene)
NDUFS3GeneProduct287327 (Entrez Gene)
NDUFS4GeneProduct327680 (Entrez Gene)
NDUFS5GeneProduct338057 (Entrez Gene)
NDUFS6GeneProduct327691 (Entrez Gene)
NDUFS7GeneProduct338079 (Entrez Gene)
NDUFS8GeneProduct287027 (Entrez Gene)
NDUFV1GeneProduct287014 (Entrez Gene)
NDUFV2GeneProduct781824 (Entrez Gene)
NDUFV3GeneProduct327717 (Entrez Gene)
O2MetaboliteHMDB01377 (HMDB)
SCO1GeneProduct508586 (Entrez Gene)
SDHAGeneProduct281480 (Entrez Gene)
SDHBGeneProduct286840 (Entrez Gene)
SDHCGeneProduct785395 (Entrez Gene)
SDHDGeneProduct281481 (Entrez Gene)
SLC25A14GeneProduct513415 (Entrez Gene)
SLC25A27GeneProduct536813 (Entrez Gene)
SLC25A4GeneProduct282478 (Entrez Gene)
SLC25A5GeneProduct282479 (Entrez Gene)
SLC25A6GeneProduct282480 (Entrez Gene)
SuccinateMetaboliteC00042 (Kegg Compound)
TCA CyclePathwayWP999 (WikiPathways)
UCP1GeneProduct281561 (Entrez Gene)
UCP2GeneProduct281562 (Entrez Gene)
UCP3GeneProduct281563 (Entrez Gene)
UCRCGeneProduct616109 (Entrez Gene)
UQCRGeneProduct281570 (Entrez Gene)
UQCRBGeneProduct616871 (Entrez Gene)
UQCRC1GeneProduct282393 (Entrez Gene)
UQCRC2GeneProduct282394 (Entrez Gene)
UQCRFS1GeneProduct287020 (Entrez Gene)
UQCRHGeneProduct613899 (Entrez Gene)
UQCRQGeneProduct286885 (Entrez Gene)
UbiquinoneMetabolite
e-MetaboliteC05359 (Kegg Compound)

Annotated Interactions

No annotated interactions
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