Genetic alterations of lung cancer (Rattus norvegicus)
From WikiPathways
Description
No description
Quality Tags
Ontology Terms
Bibliography
- Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung MC; ''HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation.''; Nat Cell Biol, 2001 PubMed Europe PMC Scholia
- Osada H, Takahashi T; ''Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.''; Oncogene, 2002 PubMed Europe PMC Scholia
- Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M; ''Repression of p15INK4b expression by Myc through association with Miz-1.''; Nat Cell Biol, 2001 PubMed Europe PMC Scholia
- Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, Roussel MF; ''Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization.''; Genes Dev, 1998 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Akt1 | GeneProduct | ENSRNOG00000028629 (Ensembl Rat) | |
Atm | GeneProduct | ENSRNOG00000029773 (Ensembl Rat) | |
CBP | GeneProduct | ENSRNOG00000002167 (Ensembl Rat) | |
Cdk2 | GeneProduct | ENSRNOG00000006469 (Ensembl Rat) | |
Cdk4 | GeneProduct | ENSRNOG00000025602 (Ensembl Rat) | |
CyclinD | GeneProduct | ||
CyclinE | GeneProduct | ENSRNOG00000002167 (Ensembl Rat) | |
DP | GeneProduct | ENSRNOG00000025602 (Ensembl Rat) | |
Dmp1 | GeneProduct | ENSRNOG00000002167 (Ensembl Rat) | |
E2f1 | GeneProduct | ENSRNOG00000016708 (Ensembl Rat) | |
ERK | GeneProduct | ||
Egfr | GeneProduct | ENSRNOG00000004332 (Ensembl Rat) | |
Erbb2 | GeneProduct | ENSRNOG00000006450 (Ensembl Rat) | |
MEK | GeneProduct | ||
MYC | GeneProduct | ||
Mdm2 | GeneProduct | ENSRNOG00000006304 (Ensembl Rat) | |
PI3K | GeneProduct | ||
RB | GeneProduct | ENSRNOG00000025602 (Ensembl Rat) | |
Raf1 | GeneProduct | ENSRNOG00000010153 (Ensembl Rat) | |
Rasl11b | GeneProduct | ENSRNOG00000002097 (Ensembl Rat) | |
SMAD4_RAT | GeneProduct | ENSRNOG00000015634 (Ensembl Rat) | |
Smad2 | GeneProduct | ENSRNOG00000018140 (Ensembl Rat) | |
TGF-beta R1/2 | GeneProduct | ENSRNOG00000002418 (Ensembl Rat) | |
Tgfb1 | GeneProduct | ENSRNOG00000020652 (Ensembl Rat) | |
Tp53 | GeneProduct | ENSRNOG00000010756 (Ensembl Rat) | |
cell cycle arrest | |||
p14ARF | GeneProduct | ENSRNOG00000002167 (Ensembl Rat) | |
p15INK4B | GeneProduct | ||
p16INK4A | GeneProduct | ||
p21 | GeneProduct | ENSRNOG00000002167 (Ensembl Rat) | |
p300 | GeneProduct | ENSRNOG00000002167 (Ensembl Rat) |
Annotated Interactions
No annotated interactions