Tryptophan metabolism (Canis familiaris)

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Indole-3-acetate5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinC00332Indole-3-acetaldehyde2-FormaminobenzoylacetateIndolepyruvate3-(2-Aminoethyl)-1H-indol-5-olAnthranilate2,3-Dihydroxyindole3-HydroxyanthranilateFormyl-5-hydroxykynurenamine8-Methoxykynurenate3-IndoleglycolaldehydeBenzoate degradation via hydroxylationIndolelactate3-MethoxyanthranilateC00877Glucobrassicin5-Hydroxy-N-formylkynurenineIndole-3-ethanolIsophenoxazine5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate2-Oxoadipate2-AminomuconateMelatonin4,6-DihydroxyquinolineOxaloacetate(Z)-5-Oxohex-2-enedioateC005277,8-Dihydro-7,8-dihydroxykynurenate2-FormylaminobenzaldehydeNicotinate and nicotinamide metabolismFormyl-N-acetyl-5-methoxykynurenamine4-(2-Aminophenyl)-2,4-dioxobutanoateKynurenate3-Hydroxy-L-kynurenine4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoateCinnavalininateN-Acetylindoxyl3-Hydroxykynurenamine2-Aminomuconate5-Hydroxyindoleacetaldehyde5-Hydroxy-L-tryptophanIndole-3-acetaldoximeN-Methyltryptamine2-OxoglutarateGlycolysis / Gluconeogenesis6-Hydroxykynurenate3-Methyldioxyindole7,8-Dihydroxykynurenate5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate4,8-Dihydroxyquinoline4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoateQuinolinate5-(2'-Formylethyl)-4,6-dihydroxypicolinate2-Amino-3-carboxymuconate3-Methylindolepyruvate5-Methoxyindoleacetate5-Hydroxyindoleacetate5-HydroxyindolepyruvateL-Tryptophanyl-tRNAAnthranilateFormylanthranilate5-HydroxyindoleacetylglycinePhenylAla, Tyr and Trp biosynthesisXanthurenicN-MethylserotoninBenzoate degradation via hydroxylation5-HydroxykynurenamineC011446-Hydroxyindolelactate2.1.1.47ASMTALDH1A1CYP1A1KYNULOC610195ALDH2ABP1ALDH21.14.16.-RHOXF2L-KynurenineDDC4.2.1.84UBR5RHOXF2CYP1A22.6.1.271.2.1.-GCDHOGDHLOC612477ALDH1A2RHOXF2PRMT1AFMID1.13.11.17IDO13.5.1.4CYP2C18IndoleALDH1A12.6.1.27CYP1B1LOC486973MAOB1.1.1.191AADATALDH1A2CYP3A4ASMTTryptamineIDO1RNF25MAOBINMTUBE3ACYP2A131.2.3.7HSD17B104.1.1.43HADH1.7.3.2ALDH9A1Acetyl-CoA1.13.11.231.14.16.33.5.99.5ALDH9A13.2.1.147N-Acetylisatin1.13.11.-1.10.3.4CYP4F122.1.1.49L-TryptophanDDCMAOB4.1.99.1ALDH3A2MDM2CYP2E13.5.1.49MDM2RHOXF2ALDH3A23.5.1.9PRMT11.14.13.91.3.1.18WARS5-HydroxykynurenineAOX1RNF25AADATTDO2N-AcetylserotoninACMSD1.4.3.2AANATKYNU1.13.99.34.1.1.-RHOXF2Formylkynurenine1.14.99.21.13.11.10TPH1DDCDHCR241.1.1.1102-Aminophenol6-HydroxymelatoninIDO11.13.12.3CYP19GCDHECHS11.5.1.-HAAO3-IndoleacetonitrileKYNUMAOBUBE3ARHOXF2Indole-3-acetamide3.5.5.1ACAT15-MethoxytryptaminePRMT1RHOXF2RHOXF22.6.1.271.1.1.1901.2.1.32CATMDM2


Description

No description

Comments

GenMAPP notes 
Converted from rat to human using ortholog information. Link to original KEGG map: http://www.genome.ad.jp/dbget-bin/show pathway?rno00380
GenMAPP remarks 
Edited by Sebastien Burel
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP465(r30270) with a 51% conversion rate.

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Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
122665view05:37, 28 April 2022EgonwMade a pathway clickable
106044view11:56, 16 August 2019MaintBotHMDB identifier normalization
104909view19:18, 24 June 2019KhanspersModified description
104908view19:18, 24 June 2019Khanspersremoved genmapp comments
104822view12:57, 19 June 2019FehrhartModified description
85637view15:35, 4 June 2016EgonwReplaced a Wikipedia ID with a ChEBI ID.
71451view19:16, 17 October 2013MaintBotAutomated update of data sources
68501view21:45, 5 July 2013MaintBotUpdated to 2013 gpml schema
48151view18:46, 9 May 2012MaintBotUpdating from human to fix xrefs
40652view21:48, 1 March 2011MaintBotRemoved redundant pathway information and comments
33945view18:18, 9 December 2009MaintBotAutomatic update of empty xrefs
32559view13:08, 17 August 2009MaintBotFixed text labels
32240view12:52, 15 August 2009MaintBotFixed text labels
31750view12:03, 14 August 2009MaintBotFixed group labels
31257view19:53, 13 August 2009MaintBotFixed text labels
30695view22:47, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1.1.1.110GeneProduct
1.1.1.190GeneProduct
1.1.1.191GeneProduct
1.10.3.4GeneProduct
1.13.11.-GeneProduct
1.13.11.10GeneProduct
1.13.11.17GeneProduct
1.13.11.23GeneProduct
1.13.12.3GeneProduct
1.13.99.3GeneProduct
1.14.13.9GeneProduct
1.14.16.-GeneProduct
1.14.16.3GeneProduct
1.14.99.2GeneProduct
1.2.1.-GeneProduct
1.2.1.32GeneProduct
1.2.3.7GeneProduct
1.3.1.18GeneProduct
1.4.3.2GeneProduct
1.5.1.-GeneProduct
1.7.3.2GeneProduct
2-AminophenolMetabolite2-Aminophenol
2.1.1.47GeneProduct
2.1.1.49GeneProduct
2.6.1.27GeneProduct
3-IndoleacetonitrileMetabolite3-Indoleacetonitrile
3.2.1.147GeneProduct
3.5.1.4GeneProduct
3.5.1.49GeneProduct
3.5.1.9GeneProduct
3.5.5.1GeneProduct
3.5.99.5GeneProduct
4.1.1.-GeneProduct
4.1.1.43GeneProduct
4.1.99.1GeneProduct
4.2.1.84GeneProduct
5-HydroxykynurenineMetabolite
5-MethoxytryptamineMetabolite
6-HydroxymelatoninMetabolite
AADATGeneProduct486059 (Entrez Gene)
AANATGeneProduct483331 (Entrez Gene)
ABP1GeneProduct475536 (Entrez Gene)
ACAT1GeneProduct489421 (Entrez Gene)
ACMSDGeneProduct476125 (Entrez Gene)
AFMIDGeneProduct609011 (Entrez Gene)
ALDH1A1GeneProduct476323 (Entrez Gene)
ALDH1A2GeneProduct478319 (Entrez Gene)
ALDH2GeneProduct610941 (Entrez Gene)
ALDH3A2GeneProduct479518 (Entrez Gene)
ALDH9A1GeneProduct
AOX1GeneProduct
ASMTGeneProduct
Acetyl-CoAMetaboliteAcetyl-CoA
CATGeneProduct403474 (Entrez Gene)
CYP19GeneProduct494003 (Entrez Gene)
CYP1A1GeneProduct487648 (Entrez Gene)
CYP1A2GeneProduct494010 (Entrez Gene)
CYP1B1GeneProduct483038 (Entrez Gene)
CYP2A13GeneProduct484494 (Entrez Gene)
CYP2C18GeneProduct
CYP2E1GeneProduct415128 (Entrez Gene)
CYP3A4GeneProduct
CYP4F12GeneProduct
DDCGeneProduct606852 (Entrez Gene)
DHCR24GeneProduct489573 (Entrez Gene) predicted
ECHS1GeneProduct480828 (Entrez Gene)
FormylkynurenineMetaboliteFormylkynurenine
GCDHGeneProduct476696 (Entrez Gene) predicted
HAAOGeneProduct611728 (Entrez Gene)
HADHGeneProduct478506 (Entrez Gene)
HSD17B10GeneProduct480930 (Entrez Gene)
IDO1GeneProduct475574 (Entrez Gene)
INMTGeneProduct489397 (Entrez Gene)
Indole-3-acetamideMetaboliteIndole-3-acetamide
IndoleMetabolite
KYNUGeneProduct483907 (Entrez Gene)
L-KynurenineMetaboliteL-Kynurenine
L-TryptophanMetabolite
LOC486973GeneProduct486973 (Entrez Gene)
LOC610195GeneProduct610195 (Entrez Gene)
LOC612477GeneProduct612477 (Entrez Gene)
MAOBGeneProduct403451 (Entrez Gene)
MDM2GeneProduct403693 (Entrez Gene)
N-AcetylisatinMetaboliteN-Acetylisatin
N-AcetylserotoninMetaboliteN-Acetylserotonin
OGDHGeneProduct475499 (Entrez Gene)
PRMT1GeneProduct476411 (Entrez Gene)
RHOXF2GeneProduct611154 (Entrez Gene)
RNF25GeneProduct478912 (Entrez Gene)
TDO2GeneProduct475476 (Entrez Gene)
TPH1GeneProduct
TryptamineMetabolite
UBE3AGeneProduct479010 (Entrez Gene)
UBR5GeneProduct475055 (Entrez Gene)
WARSGeneProduct480435 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1126"
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