IL-4 signaling pathway (Canis familiaris)

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ReceptorDDCYECSumoylationCY -> PMGlycosylationDCY -> PMTranslocationMethylationCY -> PMRecruitmentCytoplasmGolgi apparatusDemethylationMolecular associationCY -> NUDEndosomeMolecule in the pathwayDDesumoylationDEnzyme complexENUbiquitination(Protein-protein interaction)DDephosphorylationPhosphorylationProteins in a complex interactionReaction through unknown mechanisms/moleculesExtracellularAccession Number: NetPath 16ControlMTNucleusPalmitoylationGOEndoplasmic reticulumMitochondrionDProteolytic cleavageERInhibitionAcetylationCY -> PMDeubiquitinationPMNUDPlasma membraneActivationLigandAutophosphorylationCY -> NUDeacetylationPRKCIJAK1RASA1PRKD3STAT6ELK1PRKCZNFKB1JAK1INPP5DMAPK11Gene SymbolPIK3R1IRS1IL13RA1DOK2MAPK1STAMSTAT6STAT1PRKD3EP300PRKCDJAK2PTPN6PRKCIPIK3CATYK2MAPK14IL4RBADADRBK2IL4RSTAT5ABCL2L1LCKMAPK3CXCR4JAK2NCF1MAPK14FYNIL4PIK3CDCREBBPSTAT6RELAPIK3R2SHC1SOCS3HMGA1SPI1ETS1GRB2FESATF2IRS2STAT6HIST2H3CRPS6KB1PLCG1PTPN11PRKCZSOCS1SRCCBLIL4PTK2PAWRSOS1JAK3PRKCDSOCS5NFKB1IL2RGAKT1STAT6


Description

No description

Comments

GenMAPP notes 
NetPath 16 - IL-4 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP395(r28126) with a 84% conversion rate.

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Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
117988view11:23, 23 May 2021EweitzModified title
86929view13:04, 15 July 2016MkutmonOntology Term : 'interleukin-4 signaling pathway' added !
68538view22:23, 5 July 2013MaintBotUpdated to 2013 gpml schema
40694view21:50, 1 March 2011MaintBotRemoved redundant pathway information and comments
33978view18:31, 9 December 2009MaintBotAutomatic update of empty xrefs
31285view20:04, 13 August 2009MaintBotFixed text labels
30740view23:02, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADRBK2GeneProduct486327 (Entrez Gene)
AKT1GeneProduct490878 (Entrez Gene)
ATF2GeneProduct478806 (Entrez Gene)
BADGeneProduct483763 (Entrez Gene)
BCL2L1GeneProduct403618 (Entrez Gene)
CBLGeneProduct
CREBBPGeneProduct479866 (Entrez Gene)
CXCR4GeneProduct483900 (Entrez Gene)
DOK2GeneProduct486133 (Entrez Gene)
ELK1GeneProduct491860 (Entrez Gene)
EP300GeneProduct
ETS1GeneProduct489287 (Entrez Gene)
FESGeneProduct609483 (Entrez Gene)
FYNGeneProduct475032 (Entrez Gene)
GRB2GeneProduct483312 (Entrez Gene)
Gene SymbolGeneProduct
HIST2H3CGeneProduct
HMGA1GeneProduct442946 (Entrez Gene)
IL13RA1GeneProduct403623 (Entrez Gene)
IL2RGGeneProduct403851 (Entrez Gene)
IL4GeneProduct403785 (Entrez Gene)
IL4RGeneProduct489957 (Entrez Gene)
INPP5DGeneProduct
IRS1GeneProduct486148 (Entrez Gene)
IRS2GeneProduct485548 (Entrez Gene)
JAK1GeneProduct442952 (Entrez Gene)
JAK2GeneProduct484185 (Entrez Gene)
JAK3GeneProduct610004 (Entrez Gene)
LCKGeneProduct478151 (Entrez Gene)
MAPK11GeneProduct607019 (Entrez Gene)
MAPK14GeneProduct403856 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
NCF1GeneProduct607700 (Entrez Gene)
NFKB1GeneProduct442859 (Entrez Gene)
PAWRGeneProduct
PIK3CAGeneProduct488084 (Entrez Gene)
PIK3CDGeneProduct489644 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PIK3R2GeneProduct609956 (Entrez Gene)
PLCG1GeneProduct485874 (Entrez Gene)
PRKCDGeneProduct494005 (Entrez Gene)
PRKCIGeneProduct478686 (Entrez Gene)
PRKCZGeneProduct479577 (Entrez Gene)
PRKD3GeneProduct483036 (Entrez Gene)
PTK2GeneProduct475108 (Entrez Gene)
PTPN11GeneProduct477488 (Entrez Gene)
PTPN6GeneProduct486717 (Entrez Gene)
RASA1GeneProduct479158 (Entrez Gene)
RELAGeneProduct483729 (Entrez Gene)
RPS6KB1GeneProduct480580 (Entrez Gene)
SHC1GeneProduct490439 (Entrez Gene)
SOCS1GeneProduct490006 (Entrez Gene)
SOCS3GeneProduct442949 (Entrez Gene)
SOCS5GeneProduct474581 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene)
SPI1GeneProduct611255 (Entrez Gene)
SRCGeneProduct485864 (Entrez Gene)
STAMGeneProduct477990 (Entrez Gene)
STAT1GeneProduct488449 (Entrez Gene)
STAT5AGeneProduct490968 (Entrez Gene)
STAT6GeneProduct100142679 (Entrez Gene)
TYK2GeneProduct476714 (Entrez Gene)

Annotated Interactions

No annotated interactions
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