IL-7 signaling pathway (Canis familiaris)

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DeacetylationDDesumoylationProteolytic cleavageReceptorSumoylationPMECCytoplasmReaction through unknown mechanisms/moleculesNUCYDEnzyme complexENDemethylationMethylationDUbiquitinationAcetylationPhosphorylationInhibitionAccession Number: NetPath 19ExtracellularMolecular associationPlasma membraneNucleusTranslocationMolecule in the pathwayGOEndosome(Protein-protein interaction)MitochondrionRecruitmentAutophosphorylationGlycosylationPalmitoylationLigandMTControlActivationGolgi apparatusDeubiquitinationDephosphorylationProteins in a complex interactionSTAT3STAM2LYNSHC1STAMPIK3R1IRS2RAF1HRASPIK3R1MAPK3AKT1STAT5ASTAT1CBLBIL2RGCDK2IRS1MUC1MAP2K1CDK4MAP2K2PTK2BMAPK1CBLBAXBCL2L11IL7RCCND2FYNGRB2FOXO1IRF1BLKMCL1STAT5BJAK3BADSOS1JAK1CLTCGSK3BCCNA2RB1Gene SymbolFOXO3A


Description

No description

Comments

GenMAPP notes 
NetPath 19 – IL-7 Signaling Pathway


The annotation of immune signaling pathways (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use these pathways, you must cite these websites.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP205(r21111) with a 91% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
117982view11:22, 23 May 2021EweitzModified title
86941view13:09, 15 July 2016MkutmonOntology Term : 'interleukin-7 signaling pathway' added !
68595view23:21, 5 July 2013MaintBotUpdated to 2013 gpml schema
40755view21:54, 1 March 2011MaintBotRemoved redundant pathway information and comments
30700view22:49, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct490878 (Entrez Gene)
BADGeneProduct483763 (Entrez Gene)
BAXGeneProduct403523 (Entrez Gene)
BCL2L11GeneProduct612867 (Entrez Gene)
BLKGeneProduct486080 (Entrez Gene)
CBLGeneProduct
CBLBGeneProduct487965 (Entrez Gene)
CCNA2GeneProduct483845 (Entrez Gene)
CCND2GeneProduct611782 (Entrez Gene)
CDK2GeneProduct606931 (Entrez Gene)
CDK4GeneProduct481131 (Entrez Gene)
CLTCGeneProduct480578 (Entrez Gene)
FOXO1GeneProduct477295 (Entrez Gene)
FOXO3AGeneProduct
FYNGeneProduct475032 (Entrez Gene)
GRB2GeneProduct483312 (Entrez Gene)
GSK3BGeneProduct478575 (Entrez Gene)
Gene SymbolGeneProduct
HRASGeneProduct
IL2RGGeneProduct403851 (Entrez Gene)
IL7RGeneProduct612582 (Entrez Gene)
IRF1GeneProduct481500 (Entrez Gene)
IRS1GeneProduct486148 (Entrez Gene)
IRS2GeneProduct485548 (Entrez Gene)
JAK1GeneProduct442952 (Entrez Gene)
JAK3GeneProduct610004 (Entrez Gene)
LYNGeneProduct477886 (Entrez Gene)
MAP2K1GeneProduct478347 (Entrez Gene)
MAP2K2GeneProduct611939 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
MCL1GeneProduct403537 (Entrez Gene)
MUC1GeneProduct448784 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PTK2BGeneProduct486102 (Entrez Gene)
RAF1GeneProduct484648 (Entrez Gene)
RB1GeneProduct476915 (Entrez Gene)
SHC1GeneProduct490439 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene)
STAM2GeneProduct476150 (Entrez Gene)
STAMGeneProduct477990 (Entrez Gene)
STAT1GeneProduct488449 (Entrez Gene)
STAT3GeneProduct490967 (Entrez Gene)
STAT5AGeneProduct490968 (Entrez Gene)
STAT5BGeneProduct490969 (Entrez Gene)

Annotated Interactions

No annotated interactions
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