mapk cascade (Danio rerio)

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Growth and Mitogenesisp38 MAPK PathwayGiNucleusGb and GgGqStress Activated PathwaysApoptosisActivatedRap1GAPLOC567895sb:cb183GTPLOC564899GDPkrasraf1map3k3plcb3LOC560913zgc:194486LOC558321map3k12junbrafRapGAPIIMAP2K3mapk1zgc:172250mapk10SIPA1nrasHRASLOC556983mapk3zgc:194486map2k1rrasmapk14amap2k6zgc:113974zgc:92074MAPK12


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP422(r21570) with a 78% conversion rate.

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Ontology Terms

 

Bibliography

  1. Orton RJ, Sturm OE, Gormand A, Wolch W, Gilbert DR; ''Computational modelling reveals feedback redundancy within the epidermal growth factor receptor/extracellular-signal regulated kinase signalling pathway.''; IET Syst Biol, 2008 PubMed Europe PMC Scholia
  2. Plotnikov A, Zehorai E, Procaccia S, Seger R; ''The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation.''; Biochim Biophys Acta, 2011 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
116826view10:19, 14 May 2021EweitzModified title
95770view14:24, 19 January 2018MkutmonHomology conversion update
86983view14:32, 15 July 2016MkutmonOntology Term : 'mitogen activated protein kinase signaling pathway' added !
68640view04:54, 6 July 2013MaintBotUpdated to 2013 gpml schema
62804view17:46, 2 May 2013Mkutmonremove datasource annotations without identifier
62786view16:32, 2 May 2013MaintBotUpdated UniProt data source
40808view22:17, 1 March 2011MaintBotRemoved redundant pathway information and comments
34197view21:27, 9 December 2009MaintBotAutomatic update of empty xrefs
32325view13:27, 15 August 2009MaintBotFixed text labels
31931view12:55, 14 August 2009MaintBotFixed group labels
31360view20:33, 13 August 2009MaintBotFixed text labels
31053view01:23, 30 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
GDPMetabolite
GTPMetabolite
HRASGeneProduct550286 (Entrez Gene)
LOC556983GeneProduct556983 (Entrez Gene)
LOC558321GeneProduct558321 (Entrez Gene)
LOC560913GeneProduct560913 (Entrez Gene)
LOC564899GeneProduct564899 (Entrez Gene)
LOC567895GeneProduct567895 (Entrez Gene)
MAP2K3GeneProduct
MAPK12GeneProduct30681 (Entrez Gene)
RapGAPIIGeneProduct
SIPA1GeneProductnot confirmed SwissProt ID - mu: SPA1 MOUSE
brafGeneProduct403065 (Entrez Gene)
junGeneProduct335916 (Entrez Gene)
krasGeneProduct445289 (Entrez Gene)
map2k1GeneProduct406728 (Entrez Gene)
map2k6GeneProduct65239 (Entrez Gene)
map3k12GeneProduct404626 (Entrez Gene)
map3k3GeneProduct560211 (Entrez Gene)
mapk10GeneProduct569698 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mapk14aGeneProduct65237 (Entrez Gene)
mapk3GeneProduct399480 (Entrez Gene)
nrasGeneProduct30380 (Entrez Gene)
plcb3GeneProduct100001532 (Entrez Gene)
raf1GeneProduct30716 (Entrez Gene)
rrasGeneProduct449660 (Entrez Gene)
sb:cb183GeneProduct368319 (Entrez Gene)
zgc:113974GeneProduct555420 (Entrez Gene)
zgc:172250GeneProduct100002225 (Entrez Gene)
zgc:194486GeneProduct568951 (Entrez Gene)
zgc:92074GeneProduct403063 (Entrez Gene)

Annotated Interactions

No annotated interactions
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