Regulation of actin cytoskeleton (Danio rerio)

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Growth Factor (GF)Stabilizationof actinChemotatic factorGPCRActin polymerizationstress fiberFilipodiaGFFocal adhesion pathwayMAPK SignalingpathwayLamellipodiaPI3KPI3KRTKGPCRRTKActin polymerizationRASActin polymerization+p?-pFocal complexassemblyAdherens junction pathwayFocal adhesion pathwayGene ExpressionChemotactic factorRASActomyosinassembly contractionFocal adhesionassemblystress fiberPDGFRAPFN1mapk3ARPC5rock2aVAV1C11orf13fgfr3PIP5K2CLOC100150701ACTBMYLKBradykininfgf5tpteFGF20nrasPDGFBBAIAP2FGF6PIP5K1ALOC558288VIL2cfl2pik3r2PAK6FGF1tpteslc9a1ARHGEF1CFL1LOC792708LOC100004938fgf16Pik3c2bzgc:92316ROCK1fgf8afgf14zgc:153713FGF2FGF22zgc:77231tpteSSH2ARHGEF7limk1rac2pik3cdPDGFAACTN1mrasegfrLOC570868iqgap1ACTBsi:dkey-234n3.1mapk1ptk2.1Acetylcholineraf1Apc2fgf17pak1tpteLOC560360LOC442775tptepik3c3pik3r3LOC100004036APCmapk6fgf3chrm3rras2ACTBrdxPIP2chrm2adock1ARPC5GRLF1PFN1fgf23RAC1P4DKEYP-88F5.5zgc:77033fgf10afgfr4f2FGF13mosfgf12BAIAP2pak2atptegna12LOC568935chrm5aLOC560360rac1FGF11CH211-130M23.4PIP2DKEY-242K1.1pdgfrbmyh10fgf7LOC557176rrasACTG1im:7148788LOC558498ppp1r12afgfr1agng12CH211-67F24.8mapk4FGF9zgc:172250LOC559017gna13aSSH1WASF2LPSLOC561737cdc42lACTG1zgc:136560SOS1ENAHPAK3fn1pxnACTG1CD14brafzgc:92014RAC3CH211-279L9.5zgc:194528LOC100149843msnbdkrb1PIP3map2k1TMSB4XFGF18MYL3crkvclFGF21vclkrasCSKfgf4fgfr2pak7gsnaegfvil1lsi:dkey-24l11.7wu:fb92a07zgc:175192LOC564771LOC558288pip5k1awasb


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
GenMAPP remarks 
Adapted from KEGG (right-click to see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r20783) with a 66% conversion rate.

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Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
116903view11:33, 15 May 2021EweitzModified title
72128view07:53, 25 October 2013Mkutmonadded datasource to pathway data nodes
71535view19:23, 17 October 2013MaintBotAutomated update of data sources
68684view05:44, 6 July 2013MaintBotUpdated to 2013 gpml schema
47916view21:38, 18 April 2012KhanspersRemoved redundant information
47915view21:37, 18 April 2012KhanspersUpdating from human to fix xref duplication
40858view22:20, 1 March 2011MaintBotRemoved redundant pathway information and comments
34239view21:40, 9 December 2009MaintBotAutomatic update of empty xrefs
32340view13:34, 15 August 2009MaintBotFixed text labels
31956view13:03, 14 August 2009MaintBotFixed group labels
31386view20:44, 13 August 2009MaintBotFixed text labels
31092view01:38, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACTBGeneProduct
ACTG1GeneProduct
ACTN1GeneProduct560400 (Entrez Gene)
APCGeneProduct386762 (Entrez Gene)
ARHGEF1GeneProduct368266 (Entrez Gene)
ARHGEF7GeneProduct
ARPC5GeneProduct
AcetylcholineMetabolite
Apc2GeneProduct
BAIAP2GeneProduct
BradykininMetabolite
C11orf13GeneProduct
CD14GeneProduct
CFL1GeneProduct406738 (Entrez Gene)
CH211-130M23.4GeneProduct558477 (Entrez Gene)
CH211-279L9.5GeneProduct555920 (Entrez Gene)
CH211-67F24.8GeneProduct561670 (Entrez Gene)
CSKGeneProduct556454 (Entrez Gene)
DKEY-242K1.1GeneProduct560305 (Entrez Gene)
DKEYP-88F5.5GeneProduct100001221 (Entrez Gene)
ENAHGeneProduct563805 (Entrez Gene)
FGF11GeneProduct497640 (Entrez Gene)
FGF13GeneProduct492758 (Entrez Gene)
FGF1GeneProduct393733 (Entrez Gene)
FGF18GeneProduct
FGF20GeneProduct
FGF21GeneProduct724048 (Entrez Gene)
FGF22GeneProduct100005852 (Entrez Gene)
FGF2GeneProduct404231 (Entrez Gene)
FGF6GeneProduct
FGF9GeneProduct
GRLF1GeneProduct
LOC100004036GeneProduct100004036 (Entrez Gene)
LOC100004938GeneProduct100004938 (Entrez Gene)
LOC100149843GeneProduct100149843 (Entrez Gene)
LOC100150701GeneProduct100150701 (Entrez Gene)
LOC442775GeneProduct
LOC557176GeneProduct557176 (Entrez Gene)
LOC558288GeneProduct558288 (Entrez Gene)
LOC558498GeneProduct558498 (Entrez Gene)
LOC559017GeneProduct559017 (Entrez Gene)
LOC560360GeneProduct560360 (Entrez Gene)
LOC561737GeneProduct561737 (Entrez Gene)
LOC564771GeneProduct564771 (Entrez Gene)
LOC568935GeneProduct568935 (Entrez Gene)
LOC570868GeneProduct570868 (Entrez Gene)
LOC792708GeneProduct792708 (Entrez Gene)
LPSMetaboliteC00338 (Kegg Compound)
MYL3GeneProduct
MYLKGeneProduct569510 (Entrez Gene)
PAK3GeneProduct
PAK6GeneProduct
PDGFAGeneProduct
PDGFBGeneProduct565324 (Entrez Gene)
PDGFRAGeneProduct30745 (Entrez Gene)
PFN1GeneProduct799355 (Entrez Gene)
PIP2MetaboliteC04637 (Kegg Compound)
PIP3MetaboliteC05981 (Kegg Compound)
PIP5K1AGeneProduct553629 (Entrez Gene)
PIP5K2CGeneProduct
Pik3c2bGeneProduct
RAC1P4GeneProduct
RAC3GeneProduct437027 (Entrez Gene)
ROCK1GeneProduct
SOS1GeneProduct
SSH1GeneProduct559238 (Entrez Gene)
SSH2GeneProduct325085 (Entrez Gene)
TMSB4XGeneProduct
VAV1GeneProduct
VIL2GeneProduct
WASF2GeneProduct
bdkrb1GeneProduct368199 (Entrez Gene)
brafGeneProduct403065 (Entrez Gene)
cdc42lGeneProduct793158 (Entrez Gene)
cfl2GeneProduct403001 (Entrez Gene)
chrm2aGeneProduct352938 (Entrez Gene)
chrm3GeneProduct571679 (Entrez Gene)
chrm5aGeneProduct553978 (Entrez Gene)
crkGeneProduct445234 (Entrez Gene)
dock1GeneProduct572187 (Entrez Gene)
egfGeneProduct403045 (Entrez Gene)
egfrGeneProduct378478 (Entrez Gene)
f2GeneProduct325881 (Entrez Gene)
fgf10aGeneProduct359830 (Entrez Gene)
fgf12GeneProduct777735 (Entrez Gene)
fgf14GeneProduct497642 (Entrez Gene)
fgf16GeneProduct692065 (Entrez Gene)
fgf17GeneProduct407737 (Entrez Gene)
fgf23GeneProduct494456 (Entrez Gene)
fgf3GeneProduct30549 (Entrez Gene)
fgf4GeneProduct570435 (Entrez Gene)
fgf5GeneProduct494454 (Entrez Gene)
fgf7GeneProduct493181 (Entrez Gene)
fgf8aGeneProduct30538 (Entrez Gene)
fgfr1aGeneProduct30705 (Entrez Gene)
fgfr2GeneProduct352940 (Entrez Gene)
fgfr3GeneProduct58129 (Entrez Gene)
fgfr4GeneProduct100000160 (Entrez Gene)
fn1GeneProduct100005469 (Entrez Gene)
gna12GeneProduct503589 (Entrez Gene)
gna13aGeneProduct326825 (Entrez Gene)
gng12GeneProduct406604 (Entrez Gene)
gsnaGeneProduct321099 (Entrez Gene)
im:7148788GeneProduct564088 (Entrez Gene)
iqgap1GeneProduct100002928 (Entrez Gene)
krasGeneProduct445289 (Entrez Gene)
limk1GeneProduct735292 (Entrez Gene)
map2k1GeneProduct406728 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mapk3GeneProduct399480 (Entrez Gene)
mapk4GeneProduct406782 (Entrez Gene)
mapk6GeneProduct565830 (Entrez Gene)
mosGeneProduct795517 (Entrez Gene)
mrasGeneProduct564799 (Entrez Gene)
msnGeneProduct553434 (Entrez Gene)
myh10GeneProduct555454 (Entrez Gene)
nrasGeneProduct30380 (Entrez Gene)
pak1GeneProduct373103 (Entrez Gene)
pak2aGeneProduct266749 (Entrez Gene)
pak7GeneProduct405898 (Entrez Gene)
pdgfrbGeneProduct559529 (Entrez Gene)
pik3c3GeneProduct548346 (Entrez Gene)
pik3cdGeneProduct394174 (Entrez Gene)
pik3r2GeneProduct404211 (Entrez Gene)
pik3r3GeneProduct100000252 (Entrez Gene)
pip5k1aGeneProduct553629 (Entrez Gene)
ppp1r12aGeneProduct445393 (Entrez Gene)
ptk2.1GeneProduct142986 (Entrez Gene)
pxnGeneProduct399546 (Entrez Gene)
rac1GeneProduct327204 (Entrez Gene)
rac2GeneProduct415151 (Entrez Gene)
raf1GeneProduct30716 (Entrez Gene)
rdxGeneProduct286739 (Entrez Gene)
rock2aGeneProduct317747 (Entrez Gene)
rras2GeneProduct550513 (Entrez Gene)
rrasGeneProduct449660 (Entrez Gene)
si:dkey-234n3.1GeneProduct561894 (Entrez Gene)
si:dkey-24l11.7GeneProduct571356 (Entrez Gene)
slc9a1GeneProduct795135 (Entrez Gene)
tpteGeneProduct327292 (Entrez Gene)
vclGeneProduct552980 (Entrez Gene)
vil1lGeneProduct393207 (Entrez Gene)
wasbGeneProduct335158 (Entrez Gene)
wu:fb92a07GeneProduct100002263 (Entrez Gene)
zgc:136560GeneProduct692331 (Entrez Gene)
zgc:153713GeneProduct751630 (Entrez Gene)
zgc:172250GeneProduct100002225 (Entrez Gene)
zgc:175192GeneProduct568309 (Entrez Gene)
zgc:194528GeneProduct100002872 (Entrez Gene)
zgc:77033GeneProduct406598 (Entrez Gene)
zgc:77231GeneProduct336165 (Entrez Gene)
zgc:92014GeneProduct431769 (Entrez Gene)
zgc:92316GeneProduct447840 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1380"
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