GPCRs, class A rhodopsin-like (Pan troglodytes)

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Mas proto-oncogenePurinoceptor type YOther Chemokine ReceptorsRhodopsin OtherVasopressin-likeBONZO receptors (CXC6R)Fmet-leu-pheGP40 likeNeuromedin UGPR45 likeClass A OrphansMelanocortinAPJ likeOrexin & neuropeptide FFBeta AdrenoceptorsNeuropeptide Y / peptide YYLutropin-choriogonadotropic hormoneC5a anaphylatoxin(Rhod)opsinRhodopsin VertebrateInterleukin-8Olfactory OtherClass A Orphan/otherPlatelet ADP & KI01 receptorsCCKNeuropeptide YAdrenomedullin (G10D)ORPHLGR like (hormone receptors)OlfactoryChemokineC-C ChemokineAmineAcetylcholine (muscarinic)MelatoninAdrenoceptorsAlpha AdrenoceptorsThrombinPlatelet activating factorThyrotropin-releasing hormone and SecretagogueNucleotide-likeAdenosineHormone proteinFollicle stimulating hormoneBombesinPurinoceptorsEndothelinCannabisC-X-C ChemokineSREBChemokine receptor-likeOpioidSomatostatinOR1C1GPR173LOC462525HTR6HCRTR1MAS1LLOC472571HRH3Angiotensin IINPY1RSSTR2GPR174GPR161LOC468150MAS1GPR63GHSRGPR25HTR1FPTOR1D5CCR6OPN1MWDRD3P2RY10CHRM2GPR171OPN1SWP2RY11OPN3GPR42F2RL2BRS3OPN4P2RY12OPRL1MLNRP2RY2OR2B2PTGER1NMUR1CHRM5GPR3MTNR1BF2RL1ADORA2BCCR7AVPR1BADRB2HRH2CHRM4LOC466829SUCNR1LOC471937P2RY14GPR37LOC747786GPR35ADRA2BBDKRB2DRD2NPFFR1ADRA1DFSHREDNRARGL4ADORA2ALPAR4NPBWR2LOC466418GPR4GPR44DRD5ADRA2CLOC471931CNR2APLNRGPR31MC5RNPY5RLPAR5SerotoninCCKBRHTR4NPY6RGALR2GPR65HTR2CNPFFR2PTGIRAVPR1ASSTR5LOC454427OR2D2HistamineLOC468756LOC748178OR10H1DRD1P2RY5HTR1DP2RY13GPR20NMBRLOC471938LOC473227OR2C1LTB4RLOC468755LOC468152LHCGRHRH1CCRL2MC3RCCBP2AGTR2OR8B8OR2J1GPR52GPR87CYSLTR2CXCR3OR3A4EDNRBGPR34LOC454428ADRB3PTGFRCCR8NIACR2CCR2GPR37L1C3AR1PTGDRLOC747795GPR6PPYR1TBXA2RLOC740101OR1F1PTOR1D2NTSR2LOC736157MC2RF2RMC1RQ9UDD9PTGER4LOC469539TRHROPRD1ADRA1BGPR50HTR1ACHRM3FFAR1LOC747283GPR12GPR32RRHGPR83CHRM1FFAR2GALR1OR1A2P2RY4CX3CR1CXCR4LOC747846LOC471910PTOR1G1GPR15OR10A4LOC471927AGTR1MCHR1OR1E1OXTRLOC468751OR2A4OPN1LWHTR5ALOC472566CCKARCNR1FPR1OPRM1FFAR3NPBWR1PTGER3BradykininGPR68GPR45CCRL1LOC736487GALR3CCR10HTR1BADRB1GPR17MC4RLOC466417OPRK1CCR5F2RL3LOC741594NTSR1CCR1GRPRGPR19DopamineGPR22BLR1CCR4GPR77GPERLOC472567FPRL1LOC471935CMKLR1ADRA1AGPR27PTAFRHTR7GPR81CXCR7MTNR1AIL8RBIL8RALOC747344CYSLTR1HTR2ACCR3GPR39DRD4AVPR2GPR18ADORA1OR1I1BDKRB1ADORA3SSTR4P2RY1OR1E2NPY2RFPR3CCR9GPR1LOC466419SSTR1RHOXCR1GPR75PTOR1A1PTGER2P2RY6ProstaglandinNMUR2GPR21OR2N1PADRA2AHTR1ELOC471929SSTR3PRLHRLOC471941GPR85HCRTR2HTR2B


Description

No description

Comments

GenMAPP notes 
This MAPP was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP455(r21638) with a 79% conversion rate.

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Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
117400view10:35, 21 May 2021EweitzModified title
117396view10:34, 21 May 2021EweitzModified title
106943view13:40, 17 September 2019MaintBotHMDB identifier normalization
87584view02:25, 25 July 2016AlexanderPicoOntology Term : 'signaling pathway' added !
71677view19:41, 17 October 2013MaintBotAutomated update of data sources
69271view18:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
62742view03:34, 2 May 2013MaintBotUpdated UniProt data source
41579view02:00, 2 March 2011MaintBotRemoved redundant pathway information and comments
34307view22:07, 9 December 2009MaintBotAutomatic update of empty xrefs
33603view09:57, 1 December 2009MaintBotRemoved group label
31620view22:18, 13 August 2009MaintBotFixed text labels
30523view21:50, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ADORA1GeneProduct457638 (Entrez Gene)
ADORA2AGeneProduct458714 (Entrez Gene)
ADORA2BGeneProduct455009 (Entrez Gene)
ADORA3GeneProduct457108 (Entrez Gene)
ADRA1AGeneProduct
ADRA1BGeneProduct
ADRA1DGeneProduct469869 (Entrez Gene)
ADRA2AGeneProduct466201 (Entrez Gene)
ADRA2BGeneProduct459410 (Entrez Gene)
ADRA2CGeneProduct
ADRB1GeneProduct466206 (Entrez Gene)
ADRB2GeneProduct471690 (Entrez Gene)
ADRB3GeneProduct464113 (Entrez Gene)
AGTR1GeneProduct460762 (Entrez Gene)
AGTR2GeneProduct742608 (Entrez Gene)
APLNRGeneProduct466585 (Entrez Gene)
AVPR1AGeneProduct452038 (Entrez Gene)
AVPR1BGeneProduct469656 (Entrez Gene)
AVPR2GeneProduct
Angiotensin IIMetaboliteHMDB01035 (HMDB)
BDKRB1GeneProduct
BDKRB2GeneProduct467547 (Entrez Gene)
BLR1GeneProduct
BRS3GeneProduct737980 (Entrez Gene)
BradykininMetabolite
C3AR1GeneProduct466942 (Entrez Gene)
CCBP2GeneProduct460298 (Entrez Gene)
CCKARGeneProduct471163 (Entrez Gene)
CCKBRGeneProduct466414 (Entrez Gene)
CCR10GeneProduct741917 (Entrez Gene)
CCR1GeneProduct460323 (Entrez Gene)
CCR2GeneProduct740071 (Entrez Gene)
CCR3GeneProduct470810 (Entrez Gene)
CCR4GeneProduct470781 (Entrez Gene)
CCR5GeneProduct450128 (Entrez Gene)
CCR6GeneProduct
CCR7GeneProduct454654 (Entrez Gene)
CCR8GeneProduct470795 (Entrez Gene)
CCR9GeneProduct470808 (Entrez Gene)
CCRL1GeneProduct470928 (Entrez Gene)
CCRL2GeneProduct460324 (Entrez Gene)
CHRM1GeneProduct451272 (Entrez Gene)
CHRM2GeneProduct463758 (Entrez Gene)
CHRM3GeneProduct469725 (Entrez Gene)
CHRM4GeneProduct466504 (Entrez Gene)
CHRM5GeneProduct503515 (Entrez Gene)
CMKLR1GeneProduct
CNR1GeneProduct472066 (Entrez Gene)
CNR2GeneProduct456625 (Entrez Gene)
CX3CR1GeneProduct460281 (Entrez Gene)
CXCR3GeneProduct465704 (Entrez Gene)
CXCR4GeneProduct450130 (Entrez Gene)
CXCR7GeneProduct460122 (Entrez Gene)
CYSLTR1GeneProduct742228 (Entrez Gene)
CYSLTR2GeneProduct741426 (Entrez Gene)
DRD1GeneProduct
DRD2GeneProduct451553 (Entrez Gene)
DRD3GeneProduct470885 (Entrez Gene)
DRD4GeneProduct449578 (Entrez Gene)
DRD5GeneProduct473340 (Entrez Gene)
DopamineMetabolite
EDNRAGeneProduct461530 (Entrez Gene)
EDNRBGeneProduct452613 (Entrez Gene)
F2RGeneProduct471510 (Entrez Gene)
F2RL1GeneProduct461800 (Entrez Gene)
F2RL2GeneProduct
F2RL3GeneProduct455829 (Entrez Gene)
FFAR1GeneProduct468836 (Entrez Gene)
FFAR2GeneProduct455948 (Entrez Gene)
FFAR3GeneProduct455946 (Entrez Gene)
FPR1GeneProduct456254 (Entrez Gene)
FPR3GeneProduct468979 (Entrez Gene)
FPRL1GeneProduct
FSHRGeneProduct470371 (Entrez Gene)
GALR1GeneProduct468586 (Entrez Gene)
GALR2GeneProduct468332 (Entrez Gene)
GALR3GeneProduct470205 (Entrez Gene)
GHSRGeneProduct460851 (Entrez Gene)
GPERGeneProduct463215 (Entrez Gene)
GPR12GeneProduct467240 (Entrez Gene)
GPR1GeneProduct470621 (Entrez Gene)
GPR15GeneProduct450102 (Entrez Gene)
GPR161GeneProduct462973 (Entrez Gene)
GPR17GeneProduct
GPR171GeneProduct738791 (Entrez Gene)
GPR173GeneProduct
GPR174GeneProduct
GPR18GeneProduct738311 (Entrez Gene)
GPR19GeneProduct740660 (Entrez Gene)
GPR20GeneProduct737712 (Entrez Gene)
GPR21GeneProduct737039 (Entrez Gene)
GPR22GeneProduct744517 (Entrez Gene)
GPR25GeneProduct469633 (Entrez Gene)
GPR27GeneProduct
GPR31GeneProduct472189 (Entrez Gene)
GPR32GeneProduct748574 (Entrez Gene)
GPR34GeneProduct473572 (Entrez Gene)
GPR35GeneProduct460070 (Entrez Gene)
GPR3GeneProduct738558 (Entrez Gene)
GPR37GeneProduct738926 (Entrez Gene)
GPR37L1GeneProduct457626 (Entrez Gene)
GPR39GeneProduct459623 (Entrez Gene)
GPR42GeneProduct
GPR44GeneProduct466622 (Entrez Gene)
GPR4GeneProduct468922 (Entrez Gene)
GPR45GeneProduct459467 (Entrez Gene)
GPR50GeneProduct736267 (Entrez Gene)
GPR52GeneProduct457533 (Entrez Gene)
GPR63GeneProduct462890 (Entrez Gene)
GPR6GeneProduct462934 (Entrez Gene)
GPR65GeneProduct467610 (Entrez Gene)
GPR68GeneProduct453105 (Entrez Gene)
GPR75GeneProduct470376 (Entrez Gene)
GPR77GeneProduct456162 (Entrez Gene)
GPR81GeneProduct452331 (Entrez Gene)
GPR83GeneProduct466752 (Entrez Gene)
GPR85GeneProduct463664 (Entrez Gene)
GPR87GeneProduct738621 (Entrez Gene)
GRPRGeneProduct465514 (Entrez Gene)
HCRTR1GeneProduct469261 (Entrez Gene)
HCRTR2GeneProduct462786 (Entrez Gene)
HRH1GeneProduct470746 (Entrez Gene)
HRH2GeneProduct471750 (Entrez Gene)
HRH3GeneProduct
HTR1AGeneProduct471533 (Entrez Gene)
HTR1BGeneProduct462833 (Entrez Gene)
HTR1DGeneProduct469219 (Entrez Gene)
HTR1EGeneProduct472064 (Entrez Gene)
HTR1FGeneProduct470863 (Entrez Gene)
HTR2AGeneProduct467355 (Entrez Gene)
HTR2BGeneProduct737647 (Entrez Gene)
HTR2CGeneProduct473740 (Entrez Gene)
HTR4GeneProduct462175 (Entrez Gene)
HTR5AGeneProduct463837 (Entrez Gene)
HTR6GeneProduct469199 (Entrez Gene)
HTR7GeneProduct466154 (Entrez Gene)
HistamineMetabolite
IL8RAGeneProduct470645 (Entrez Gene)
IL8RBGeneProduct470644 (Entrez Gene)
LHCGRGeneProduct
LOC454427GeneProduct454427 (Entrez Gene)
LOC454428GeneProduct454428 (Entrez Gene)
LOC462525GeneProduct462525 (Entrez Gene)
LOC466417GeneProduct466417 (Entrez Gene)
LOC466418GeneProduct466418 (Entrez Gene)
LOC466419GeneProduct466419 (Entrez Gene)
LOC466829GeneProduct466829 (Entrez Gene)
LOC468150GeneProduct468150 (Entrez Gene)
LOC468152GeneProduct468152 (Entrez Gene)
LOC468751GeneProduct468751 (Entrez Gene)
LOC468755GeneProduct468755 (Entrez Gene)
LOC468756GeneProduct468756 (Entrez Gene)
LOC469539GeneProduct469539 (Entrez Gene)
LOC471910GeneProduct471910 (Entrez Gene)
LOC471927GeneProduct471927 (Entrez Gene)
LOC471929GeneProduct471929 (Entrez Gene)
LOC471931GeneProduct471931 (Entrez Gene)
LOC471935GeneProduct471935 (Entrez Gene)
LOC471937GeneProduct471937 (Entrez Gene)
LOC471938GeneProduct471938 (Entrez Gene)
LOC471941GeneProduct471941 (Entrez Gene)
LOC472566GeneProduct472566 (Entrez Gene)
LOC472567GeneProduct472567 (Entrez Gene)
LOC472571GeneProduct472571 (Entrez Gene)
LOC473227GeneProduct473227 (Entrez Gene)
LOC736157GeneProduct736157 (Entrez Gene)
LOC736487GeneProduct736487 (Entrez Gene)
LOC740101GeneProduct740101 (Entrez Gene)
LOC741594GeneProduct741594 (Entrez Gene)
LOC747283GeneProduct747283 (Entrez Gene)
LOC747344GeneProduct747344 (Entrez Gene)
LOC747786GeneProduct747786 (Entrez Gene)
LOC747795GeneProduct747795 (Entrez Gene)
LOC747846GeneProduct747846 (Entrez Gene)
LOC748178GeneProduct748178 (Entrez Gene)
LPAR4GeneProduct465729 (Entrez Gene)
LPAR5GeneProduct747759 (Entrez Gene)
LTB4RGeneProduct452818 (Entrez Gene)
MAS1GeneProduct472176 (Entrez Gene)
MAS1LGeneProduct462526 (Entrez Gene)
MC1RGeneProduct493980 (Entrez Gene)
MC2RGeneProduct455500 (Entrez Gene)
MC3RGeneProduct469978 (Entrez Gene)
MC4RGeneProduct468556 (Entrez Gene)
MC5RGeneProduct468599 (Entrez Gene)
MCHR1GeneProduct470220 (Entrez Gene)
MLNRGeneProduct
MTNR1AGeneProduct471417 (Entrez Gene)
MTNR1BGeneProduct466747 (Entrez Gene)
NIACR2GeneProduct452411 (Entrez Gene)
NMBRGeneProduct472141 (Entrez Gene)
NMUR1GeneProduct739217 (Entrez Gene)
NMUR2GeneProduct471713 (Entrez Gene)
NPBWR1GeneProduct739992 (Entrez Gene)
NPBWR2GeneProduct458427 (Entrez Gene)
NPFFR1GeneProduct466099 (Entrez Gene)
NPFFR2GeneProduct471213 (Entrez Gene)
NPY1RGeneProduct471331 (Entrez Gene)
NPY2RGeneProduct461562 (Entrez Gene)
NPY5RGeneProduct461582 (Entrez Gene)
NPY6RGeneProduct
NTSR1GeneProduct458392 (Entrez Gene)
NTSR2GeneProduct745294 (Entrez Gene)
OPN1LWGeneProduct741998 (Entrez Gene)
OPN1MWGeneProduct
OPN1SWGeneProduct472508 (Entrez Gene)
OPN3GeneProduct457854 (Entrez Gene)
OPN4GeneProduct735531 (Entrez Gene)
OPRD1GeneProduct456688 (Entrez Gene)
OPRK1GeneProduct
OPRL1GeneProduct
OPRM1GeneProduct472165 (Entrez Gene)
OR10A4GeneProduct
OR10H1GeneProduct
OR1A2GeneProduct
OR1C1GeneProduct
OR1E1GeneProduct
OR1E2GeneProduct
OR1F1GeneProduct
OR1I1GeneProduct
OR2A4GeneProduct
OR2B2GeneProduct
OR2C1GeneProduct
OR2D2GeneProduct
OR2J1GeneProduct
OR2N1PGeneProduct
OR3A4GeneProduct
OR8B8GeneProduct
OXTRGeneProduct738742 (Entrez Gene)
P2RY10GeneProduct
P2RY11GeneProduct
P2RY12GeneProduct738917 (Entrez Gene)
P2RY13GeneProduct738859 (Entrez Gene)
P2RY1GeneProduct470970 (Entrez Gene)
P2RY14GeneProduct738743 (Entrez Gene)
P2RY2GeneProduct466702 (Entrez Gene)
P2RY4GeneProduct473656 (Entrez Gene)
P2RY5GeneProduct741241 (Entrez Gene)
P2RY6GeneProduct451410 (Entrez Gene)
PPYR1GeneProduct747423 (Entrez Gene)
PRLHRGeneProduct466259 (Entrez Gene)
PTAFRGeneProduct469249 (Entrez Gene)
PTGDRGeneProduct452906 (Entrez Gene)
PTGER1GeneProduct747643 (Entrez Gene)
PTGER2GeneProduct467459 (Entrez Gene)
PTGER3GeneProduct456940 (Entrez Gene)
PTGER4GeneProduct450195 (Entrez Gene)
PTGFRGeneProduct456970 (Entrez Gene)
PTGIRGeneProduct
PTOR1A1GeneProduct468149 (Entrez Gene)
PTOR1D2GeneProduct468145 (Entrez Gene)
PTOR1D5GeneProduct468144 (Entrez Gene)
PTOR1G1GeneProduct454426 (Entrez Gene)
ProstaglandinMetabolite
Q9UDD9GeneProduct
RGL4GeneProduct458697 (Entrez Gene)
RHOGeneProduct460685 (Entrez Gene)
RRHGeneProduct736907 (Entrez Gene)
SSTR1GeneProduct467434 (Entrez Gene)
SSTR2GeneProduct454854 (Entrez Gene)
SSTR3GeneProduct741644 (Entrez Gene)
SSTR4GeneProduct469897 (Entrez Gene)
SSTR5GeneProduct453812 (Entrez Gene)
SUCNR1GeneProduct738824 (Entrez Gene)
SerotoninMetabolite
TBXA2RGeneProduct468667 (Entrez Gene)
TRHRGeneProduct472842 (Entrez Gene)
XCR1GeneProduct460321 (Entrez Gene)

Annotated Interactions

No annotated interactions
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