Biogenic amine synthesis (Rattus norvegicus)

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1Synthesis pathways for biogenic aminesfollow solid arrows through enzymatic steps,while degradation steps follow dashed arrows.AcetylserotoninChatSerotoninMaoaMelatoninHistamineGad2PhenylalanineComtTyrosineEpinephrineHistidineDdcHdcAsmtGad1TryptophanTph1MaoaDbhL-DOPA5-hydroxy-tryptophanNorepinephrineGlutamateCholineDdcAcetylcholineThACHEAanatPahPNMTDopamineGABADdc


Description

Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source: http://www.whatislife.com/reader2/Metabolism/pathway/Neurotransmitter.html

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP550(r21838) with a 50% conversion rate.

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Ontology Terms

 

Bibliography

  1. Purves, Dale, Augustine, George J., Fitzpatrick, David, Katz, Lawrence C., LaMantia, Anthony-Samuel, McNamara, James O., Williams, S. Mark.; ''Neuroscience''; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=neurosci&part=A405, 2001

History

View all...
CompareRevisionActionTimeUserComment
116952view10:06, 16 May 2021EweitzModified title
106977view13:43, 17 September 2019MaintBotHMDB identifier normalization
89526view11:03, 16 September 2016Mkutmonontology tag fix
89482view13:39, 15 September 2016Mkutmonremove space from ontology term id
71782view20:31, 17 October 2013MaintBotAutomated update of data sources
69364view18:54, 8 July 2013MaintBotUpdated to 2013 gpml schema
67086view10:04, 26 June 2013Christine ChichesterOntology Term : 'biogenic amine biosynthetic pathway' added !
41678view02:36, 2 March 2011MaintBotRemoved redundant pathway information and comments
35165view14:43, 11 February 2010ThomasModified description
35164view14:43, 11 February 2010Thomasadded literature
34068view19:09, 9 December 2009MaintBotAutomatic update of empty xrefs
32398view17:01, 15 August 2009MaintBotFixed text labels
32049view13:31, 14 August 2009MaintBotFixed group labels
31431view21:02, 13 August 2009MaintBotFixed text labels
30947view00:42, 30 July 2009MaintBotConverted from Homo sapiens
21359view11:31, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Biogenic Amine Synthesis]] moved to [[Pathway:WP323]]: Moved to stable identifier
7924view13:46, 7 January 2008MaintBot[[Pathway:Rat:Biogenic Amine Synthesis]] moved to [[Pathway:Rattus norvegicus:Biogenic Amine Synthesis]]: Renaming species
7587view16:02, 18 December 2007MaintBotfixed category names
7333view12:42, 4 November 2007MaintBotAdded categories to GPML
6521view22:19, 22 May 2007AlexanderPicogpml file for [[Rat:Biogenic_Amine_Synthesis]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
5-hydroxy-tryptophanMetabolite
ACHEGeneProduct83817 (Entrez Gene)
AanatGeneProduct25120 (Entrez Gene)
AcetylcholineMetabolite
AcetylserotoninMetabolite
AsmtGeneProduct246281 (Entrez Gene)
ChatGeneProduct290567 (Entrez Gene)
CholineMetabolite
ComtGeneProduct24267 (Entrez Gene)
DbhGeneProduct25699 (Entrez Gene)
DdcGeneProduct24311 (Entrez Gene)
DopamineMetabolite
EpinephrineMetaboliteHMDB00068 (HMDB)
GABAMetaboliteHMDB00112 (HMDB)
Gad1GeneProduct24379 (Entrez Gene)
Gad2GeneProduct24380 (Entrez Gene)
GlutamateMetabolite
HdcGeneProduct24443 (Entrez Gene)
HistamineMetabolite
HistidineMetabolite
L-DOPAMetabolite
MaoaGeneProduct29253 (Entrez Gene)
MelatoninMetaboliteHMDB01389 (HMDB)
NorepinephrineMetabolite
PNMTGeneProduct24661 (Entrez Gene)
PahGeneProduct24616 (Entrez Gene)
PhenylalanineMetabolite
SerotoninMetabolite
ThGeneProduct25085 (Entrez Gene)
Tph1GeneProduct24848 (Entrez Gene)
TryptophanMetabolite
TyrosineMetabolite

Annotated Interactions

No annotated interactions
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