Regulation of actin cytoskeleton (Rattus norvegicus)

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Growth Factor (GF)Stabilizationof actinChemotatic factorGPCRActin polymerizationstress fiberFilipodiaGFFocal adhesion pathwayMAPK SignalingpathwayLamellipodiaPI3KPI3KRTKGPCRRTKActin polymerizationRASActin polymerization+p?-pFocal complexassemblyAdherens junction pathwayFocal adhesion pathwayGene ExpressionChemotactic factorRASActomyosinassembly contractionFocal adhesionassemblystress 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


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
GenMAPP remarks 
Adapted from KEGG (right-click to see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r20783) with a 90% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
117008view11:21, 16 May 2021EweitzModified title
109392view16:03, 16 March 2020L DupuisConverted interactions to graphical lines
105000view04:50, 28 June 2019Khanspersremoved KEGG comments
72164view12:24, 25 October 2013EgonwAdded missing metabolite IDs.
71785view20:32, 17 October 2013MaintBotAutomated update of data sources
71299view16:58, 17 October 2013MaintBotAutomated update of data sources
69385view18:57, 8 July 2013MaintBotUpdated to 2013 gpml schema
67622view11:34, 26 June 2013DdiglesOntology Term : 'cell adhesion signaling pathway' added !
47758view05:00, 6 April 2012Khanspersupdated xref
47757view04:58, 6 April 2012Khanspersupdated xrefs
41701view02:37, 2 March 2011MaintBotRemoved redundant pathway information and comments
34083view19:13, 9 December 2009MaintBotAutomatic update of empty xrefs
32406view17:03, 15 August 2009MaintBotFixed text labels
32061view13:34, 14 August 2009MaintBotFixed group labels
31436view21:04, 13 August 2009MaintBotFixed text labels
31003view01:01, 30 July 2009MaintBotConverted from Homo sapiens
21415view11:31, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Regulation of Actin Cytoskeleton KEGG]] moved to [[Pathway:WP351]]: Moved to stable identifier
8358view13:46, 7 January 2008MaintBot[[Pathway:Rat:Regulation of Actin Cytoskeleton KEGG]] moved to [[Pathway:Rattus norvegicus:Regulation of Actin Cytoskeleton KEGG]]: Renaming species
7797view16:18, 18 December 2007MaintBotfixed category names
7291view12:41, 4 November 2007MaintBotAdded categories to GPML
6590view22:20, 22 May 2007169.230.77.174gpml file for [[Rat:Regulation_of_Actin_Cytoskeleton_KEGG]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Abi2GeneProduct286928 (Entrez Gene)
AcetylcholineMetabolite
ActbGeneProduct81822 (Entrez Gene)
Actg1GeneProduct287876 (Entrez Gene)
Actn1GeneProduct81634 (Entrez Gene)
Apc2GeneProduct299611 (Entrez Gene)
ApcGeneProduct24205 (Entrez Gene)
Arhgef1GeneProduct60323 (Entrez Gene)
Arhgef4GeneProduct301334 (Entrez Gene)
Arhgef6GeneProduct363509 (Entrez Gene)
Arhgef7GeneProduct114559 (Entrez Gene)
Arpc5GeneProduct360854 (Entrez Gene)
Baiap2GeneProduct117542 (Entrez Gene)
Bcar1GeneProduct25414 (Entrez Gene)
Bdkrb1GeneProduct81509 (Entrez Gene)
Bdkrb2GeneProduct25245 (Entrez Gene)
BradykininMetabolite
BrafGeneProduct114486 (Entrez Gene)
CDC42GeneProduct64465 (Entrez Gene)
CYFIP2GeneProduct303073 (Entrez Gene)
Cd14GeneProduct60350 (Entrez Gene)
Cfl1GeneProduct29271 (Entrez Gene)
Cfl2GeneProduct366624 (Entrez Gene)
Chrm1GeneProduct25229 (Entrez Gene)
Chrm2GeneProduct81645 (Entrez Gene)
Chrm3GeneProduct24260 (Entrez Gene)
Chrm4GeneProduct25111 (Entrez Gene)
Chrm5GeneProduct53949 (Entrez Gene)
CrkGeneProduct54245 (Entrez Gene)
CskGeneProduct315707 (Entrez Gene)
Dock1GeneProduct309081 (Entrez Gene)
EgfGeneProduct25313 (Entrez Gene)
EgfrGeneProduct24329 (Entrez Gene)
EnahGeneProduct360891 (Entrez Gene)
EzrGeneProduct54319 (Entrez Gene)
F2GeneProduct29251 (Entrez Gene)
F2rGeneProduct25439 (Entrez Gene)
FGF18GeneProduct29369 (Entrez Gene)
Fgd1GeneProduct363460 (Entrez Gene)
Fgf10GeneProduct25443 (Entrez Gene)
Fgf11GeneProduct170632 (Entrez Gene)
Fgf12GeneProduct170630 (Entrez Gene)
Fgf1GeneProduct25317 (Entrez Gene)
Fgf13GeneProduct84488 (Entrez Gene)
Fgf14GeneProduct63851 (Entrez Gene)
Fgf16GeneProduct60464 (Entrez Gene)
Fgf17GeneProduct29368 (Entrez Gene)
Fgf20GeneProduct66017 (Entrez Gene)
Fgf21GeneProduct170580 (Entrez Gene)
Fgf22GeneProduct170579 (Entrez Gene)
Fgf23GeneProduct170583 (Entrez Gene)
Fgf2GeneProduct54250 (Entrez Gene)
Fgf3GeneProduct170633 (Entrez Gene)
Fgf4GeneProduct116499 (Entrez Gene)
Fgf5GeneProduct60662 (Entrez Gene)
Fgf6GeneProduct170700 (Entrez Gene)
Fgf7GeneProduct29348 (Entrez Gene)
Fgf8GeneProduct29349 (Entrez Gene)
Fgf9GeneProduct25444 (Entrez Gene)
Fgfr1GeneProduct79114 (Entrez Gene)
Fgfr2GeneProduct25022 (Entrez Gene)
Fgfr3GeneProduct84489 (Entrez Gene)
Fgfr4GeneProduct25114 (Entrez Gene)
Fn1GeneProduct25661 (Entrez Gene)
Git1GeneProduct83709 (Entrez Gene)
Gna12GeneProduct81663 (Entrez Gene)
Gna13GeneProduct303634 (Entrez Gene)
Gng12GeneProduct114120 (Entrez Gene)
Grlf1GeneProduct306400 (Entrez Gene)
GsnGeneProduct296654 (Entrez Gene)
Gstt2GeneProduct29487 (Entrez Gene)
Iqgap1GeneProduct361598 (Entrez Gene)
Itga1GeneProduct25118 (Entrez Gene)
KrasGeneProduct24525 (Entrez Gene)
LOC442775GeneProduct
LPSMetaboliteC00338 (Kegg Compound)
Limk1GeneProduct65172 (Entrez Gene)
Map2k1GeneProduct170851 (Entrez Gene)
Map2k2GeneProduct58960 (Entrez Gene)
Mapk1GeneProduct116590 (Entrez Gene)
Mapk3GeneProduct50689 (Entrez Gene)
Mapk4GeneProduct54268 (Entrez Gene)
Mapk6GeneProduct58840 (Entrez Gene)
MosGeneProduct24559 (Entrez Gene)
MrasGeneProduct25482 (Entrez Gene)
MsnGeneProduct81521 (Entrez Gene)
Myh10GeneProduct79433 (Entrez Gene)
Myl1GeneProduct56781 (Entrez Gene)
Myl3GeneProduct24585 (Entrez Gene)
MylkGeneProduct288057 (Entrez Gene)
Nckap1GeneProduct58823 (Entrez Gene)
NrasGeneProduct24605 (Entrez Gene)
PIK3CAGeneProduct170911 (Entrez Gene)
PIP2MetaboliteC04637 (Kegg Compound)
PIP3MetaboliteC05981 (Kegg Compound)
PIP5K1AGeneProduct365865 (Entrez Gene)
PIP5KL1GeneProduct
Pak1GeneProduct29431 (Entrez Gene)
Pak2GeneProduct29432 (Entrez Gene)
Pak3GeneProduct29433 (Entrez Gene)
Pak4GeneProduct292756 (Entrez Gene)
Pak6GeneProduct296078 (Entrez Gene)
Pak7GeneProduct311450 (Entrez Gene)
PdgfaGeneProduct25266 (Entrez Gene)
PdgfbGeneProduct24628 (Entrez Gene)
PdgfraGeneProduct25267 (Entrez Gene)
PdgfrbGeneProduct24629 (Entrez Gene)
Pfn1GeneProduct64303 (Entrez Gene)
Pik3c2aGeneProduct361632 (Entrez Gene)
Pik3c2bGeneProduct289021 (Entrez Gene)
Pik3c2gGeneProduct116720 (Entrez Gene)
Pik3c3GeneProduct65052 (Entrez Gene)
Pik3cbGeneProduct85243 (Entrez Gene)
Pik3cdGeneProduct366508 (Entrez Gene)
Pik3cgGeneProduct298947 (Entrez Gene)
Pik3r1GeneProduct25513 (Entrez Gene)
Pik3r2GeneProduct29741 (Entrez Gene)
Pik3r3GeneProduct60664 (Entrez Gene)
Pik3r4GeneProduct363131 (Entrez Gene)
Pik3r5GeneProduct497931 (Entrez Gene)
Pip4k2aGeneProduct116723 (Entrez Gene)
Pip4k2bGeneProduct89812 (Entrez Gene)
Pip4k2cGeneProduct140607 (Entrez Gene)
Pip5k1bGeneProduct309419 (Entrez Gene)
Pip5k1cGeneProduct314641 (Entrez Gene)
Ppp1r12aGeneProduct116670 (Entrez Gene)
Ptk2GeneProduct25614 (Entrez Gene)
PxnGeneProduct360820 (Entrez Gene)
RAC1P4GeneProduct
RAC3GeneProduct
Rac1GeneProduct363875 (Entrez Gene)
Rac2GeneProduct366957 (Entrez Gene)
Raf1GeneProduct24703 (Entrez Gene)
Rassf7GeneProduct293623 (Entrez Gene)
RdxGeneProduct315655 (Entrez Gene)
RhoaGeneProduct117273 (Entrez Gene)
Rock1GeneProduct81762 (Entrez Gene)
Rock2GeneProduct25537 (Entrez Gene)
Rras2GeneProduct365355 (Entrez Gene)
RrasGeneProduct361568 (Entrez Gene)
SOS2GeneProduct85384 (Entrez Gene)
Slc9a1GeneProduct24782 (Entrez Gene)
Sos1GeneProduct313845 (Entrez Gene)
Ssh1GeneProduct304580 (Entrez Gene)
Ssh2GeneProduct303342 (Entrez Gene)
Ssh3GeneProduct365396 (Entrez Gene)
TMSB4XGeneProduct81814 (Entrez Gene)
Vav1GeneProduct25156 (Entrez Gene)
VclGeneProduct305679 (Entrez Gene)
Vil1GeneProduct316521 (Entrez Gene)
WASGeneProduct317371 (Entrez Gene)
Wasf1GeneProduct294568 (Entrez Gene)
Wasf2GeneProduct313024 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP351"
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