Adipogenesis (Rattus norvegicus)

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1Transcription Factors/ModulatorsDifferentiated adipocyteMiscellaneousFully Differentiated Adipocyte MarkersGrowth Factors/HormonesAdipocyte Secretory ProductsPreadipocyteInhibitors of Preadipocyte to Adipocyte TransitionPossible Lipodystrophy GenesInsulin Action GenesFoxo1Pck1TnfAsipWnt10bLpin2Pnpla3Hif1aLipeMef2dCntfrHmga1Nr2f1Ctnnb1Il6stPpardSp1Irs2Stat5bPtgisAgtGH1Igf1Twist1Gdf10OsmLpin1Creb1Rbl1Bmp4Bscl2Smad3Ncor2Nr1h3Pck2NamptId3Ebf1Wnt1Bmp3Mixl1NdnLpin3PrlrSerpine1Rbl2Stat6Cugbp1Il6RoraMEF2ACebpaCebpbSocs3Gata2Wwtr1Hnf1aLmnaLifMbnl1PparaPlinSlc2a4MifCdkn1aPpargRaraWnt5bE2F4FOXC2IRS3LIns2RxrgKlf15Stat1Ddit3Spock1RxraNcoa1Srebf1Egr2Bmp1Tgfb1FasAgpat2Gata3Bmp2CfdCyp26b1CEBPDScd1Sfrp4AdfpRetnGadd45aE2f1Epas1LplIrs1Nr3c1Ppargc1aKlf6Dlk1Dvl1MEF2BNrip1Socs1Klf7Mef2cNcoa2FrzbAhrGadd45bAdipoqZmpste24LifrTrib3IRS4Cyp26a1LepStat5aGTF3AStat2Stat3Fzd1NCOR1Cisd1Klf5Rb1Ucp1Gata4


Description

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP236(r28133) with a 92% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Rosen ED, Spiegelman BM; ''Molecular regulation of adipogenesis.''; Annu Rev Cell Dev Biol, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
87029view14:50, 15 July 2016MkutmonOntology Term : 'signaling pathway pertinent to development' added !
69397view18:59, 8 July 2013MaintBotUpdated to 2013 gpml schema
41714view02:38, 2 March 2011MaintBotRemoved redundant pathway information and comments
35352view09:04, 12 February 2010MartijnVanIerselModified description
35346view08:59, 12 February 2010MartijnVanIerseladded lit. ref.
34093view19:17, 9 December 2009MaintBotAutomatic update of empty xrefs
30934view00:38, 30 July 2009MaintBotConverted from Homo sapiens
21007view11:30, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Adipogenesis]] moved to [[Pathway:WP155]]: Moved to stable identifier
7888view13:46, 7 January 2008MaintBot[[Pathway:Rat:Adipogenesis]] moved to [[Pathway:Rattus norvegicus:Adipogenesis]]: Renaming species
7569view16:00, 18 December 2007MaintBotfixed category names
7454view12:42, 4 November 2007MaintBotAdded categories to GPML
6515view22:19, 22 May 2007M.Pattigpml file for [[Rat:Adipogenesis]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AdfpGeneProduct298199 (Entrez Gene)
AdipoqGeneProduct246253 (Entrez Gene)
Agpat2GeneProduct311821 (Entrez Gene)
AgtGeneProduct24179 (Entrez Gene)
AhrGeneProduct25690 (Entrez Gene)
AsipGeneProduct24152 (Entrez Gene)
Bmp1GeneProduct83470 (Entrez Gene)
Bmp2GeneProduct29373 (Entrez Gene)
Bmp3GeneProduct25667 (Entrez Gene)
Bmp4GeneProduct25296 (Entrez Gene)
Bscl2GeneProduct361722 (Entrez Gene)
CEBPDGeneProduct25695 (Entrez Gene)
Cdkn1aGeneProduct114851 (Entrez Gene)
CebpaGeneProduct24252 (Entrez Gene)
CebpbGeneProduct24253 (Entrez Gene)
CfdGeneProduct54249 (Entrez Gene)
Cisd1GeneProduct294362 (Entrez Gene)
CntfrGeneProduct313173 (Entrez Gene)
Creb1GeneProduct81646 (Entrez Gene)
Ctnnb1GeneProduct84353 (Entrez Gene)
Cugbp1GeneProduct362160 (Entrez Gene)
Cyp26a1GeneProduct154985 (Entrez Gene)
Cyp26b1GeneProduct312495 (Entrez Gene)
Ddit3GeneProduct29467 (Entrez Gene)
Dlk1GeneProduct114587 (Entrez Gene)
Dvl1GeneProduct83721 (Entrez Gene)
E2F4GeneProduct307794 (Entrez Gene)
E2f1GeneProduct399489 (Entrez Gene)
Ebf1GeneProduct116543 (Entrez Gene)
Egr2GeneProduct114090 (Entrez Gene)
Epas1GeneProduct29452 (Entrez Gene)
FOXC2GeneProduct171356 (Entrez Gene)
FasGeneProduct246097 (Entrez Gene)
Foxo1GeneProduct84482 (Entrez Gene)
FrzbGeneProduct295691 (Entrez Gene)
Fzd1GeneProduct58868 (Entrez Gene)
GH1GeneProduct24391 (Entrez Gene)
GTF3AGeneProduct246299 (Entrez Gene)
Gadd45aGeneProduct25112 (Entrez Gene)
Gadd45bGeneProduct299626 (Entrez Gene)
Gata2GeneProduct25159 (Entrez Gene)
Gata3GeneProduct85471 (Entrez Gene)
Gata4GeneProduct54254 (Entrez Gene)
Gdf10GeneProduct79216 (Entrez Gene)
Hif1aGeneProduct29560 (Entrez Gene)
Hmga1GeneProduct117062 (Entrez Gene)
Hnf1aGeneProduct24817 (Entrez Gene)
IRS3LGeneProduct
IRS4GeneProduct315350 (Entrez Gene)
Id3GeneProduct25585 (Entrez Gene)
Igf1GeneProduct24482 (Entrez Gene)
Il6GeneProduct24498 (Entrez Gene)
Il6stGeneProduct25205 (Entrez Gene)
Ins2GeneProduct24506 (Entrez Gene)
Irs1GeneProduct25467 (Entrez Gene)
Irs2GeneProduct29376 (Entrez Gene)
Klf15GeneProduct85497 (Entrez Gene)
Klf5GeneProduct84410 (Entrez Gene)
Klf6GeneProduct58954 (Entrez Gene)
Klf7GeneProduct363243 (Entrez Gene)
LepGeneProduct25608 (Entrez Gene)
LifGeneProduct60584 (Entrez Gene)
LifrGeneProduct81680 (Entrez Gene)
LipeGeneProduct25330 (Entrez Gene)
LmnaGeneProduct60374 (Entrez Gene)
Lpin1GeneProduct313977 (Entrez Gene)
Lpin2GeneProduct316737 (Entrez Gene)
Lpin3GeneProduct362261 (Entrez Gene)
LplGeneProduct24539 (Entrez Gene)
MEF2AGeneProduct309957 (Entrez Gene)
MEF2BGeneProduct498607 (Entrez Gene)
Mbnl1GeneProduct282635 (Entrez Gene)
Mef2cGeneProduct499497 (Entrez Gene)
Mef2dGeneProduct81518 (Entrez Gene)
MifGeneProduct81683 (Entrez Gene)
Mixl1GeneProduct289311 (Entrez Gene)
NCOR1GeneProduct54299 (Entrez Gene)
NamptGeneProduct297508 (Entrez Gene)
Ncoa1GeneProduct313929 (Entrez Gene)
Ncoa2GeneProduct83724 (Entrez Gene)
Ncor2GeneProduct360801 (Entrez Gene)
NdnGeneProduct308690 (Entrez Gene)
Nr1h3GeneProduct58852 (Entrez Gene)
Nr2f1GeneProduct81808 (Entrez Gene)
Nr3c1GeneProduct24413 (Entrez Gene)
Nrip1GeneProduct304157 (Entrez Gene)
OsmGeneProduct289747 (Entrez Gene)
Pck1GeneProduct362282 (Entrez Gene)
Pck2GeneProduct361042 (Entrez Gene)
PlinGeneProduct25629 (Entrez Gene)
Pnpla3GeneProduct362972 (Entrez Gene)
PparaGeneProduct25747 (Entrez Gene)
PpardGeneProduct25682 (Entrez Gene)
PpargGeneProduct25664 (Entrez Gene)
Ppargc1aGeneProduct83516 (Entrez Gene)
PrlrGeneProduct24684 (Entrez Gene)
PtgisGeneProduct25527 (Entrez Gene)
RaraGeneProduct24705 (Entrez Gene)
Rb1GeneProduct24708 (Entrez Gene)
Rbl1GeneProduct680111 (Entrez Gene)
Rbl2GeneProduct81758 (Entrez Gene)
RetnGeneProduct246250 (Entrez Gene)
RoraGeneProduct300807 (Entrez Gene)
RxraGeneProduct25271 (Entrez Gene)
RxrgGeneProduct83574 (Entrez Gene)
Scd1GeneProduct246074 (Entrez Gene)
Serpine1GeneProduct24617 (Entrez Gene)
Sfrp4GeneProduct89803 (Entrez Gene)
Slc2a4GeneProduct25139 (Entrez Gene)
Smad3GeneProduct25631 (Entrez Gene)
Socs1GeneProduct252971 (Entrez Gene)
Socs3GeneProduct89829 (Entrez Gene)
Sp1GeneProduct24790 (Entrez Gene)
Spock1GeneProduct306759 (Entrez Gene)
Srebf1GeneProduct78968 (Entrez Gene)
Stat1GeneProduct25124 (Entrez Gene)
Stat2GeneProduct288774 (Entrez Gene)
Stat3GeneProduct25125 (Entrez Gene)
Stat5aGeneProduct24918 (Entrez Gene)
Stat5bGeneProduct25126 (Entrez Gene)
Stat6GeneProduct362896 (Entrez Gene)
Tgfb1GeneProduct59086 (Entrez Gene)
TnfGeneProduct24835 (Entrez Gene)
Trib3GeneProduct246273 (Entrez Gene)
Twist1GeneProduct85489 (Entrez Gene)
Ucp1GeneProduct24860 (Entrez Gene)
Wnt10bGeneProduct315294 (Entrez Gene)
Wnt1GeneProduct24881 (Entrez Gene)
Wnt5bGeneProduct282582 (Entrez Gene)
Wwtr1GeneProduct295062 (Entrez Gene)
Zmpste24GeneProduct313564 (Entrez Gene)

Annotated Interactions

No annotated interactions
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