Iron metabolism in placenta (Homo sapiens)
From WikiPathways
Description
During pregnancy, iron is transported from mother to fetus across the placenta. Iron is essential for many biological processes, including the transfer of oxygen in blood, but it can also be toxic. Elaborate and elegant mechanisms have evolved to make sure that the potential for oxidative damage is minimized. This description of Iron pathway through the placenta, and its regulation is purposed to understand the effect of Iron deficiency or Iron overload of the mother on the fetus.
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Bibliography
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History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
HAMP | Protein | ENSG00000105697 (Ensembl Human) ![]() | |
HEPHL1 | GeneProduct | ENSG00000181333 (Ensembl Human) ![]() | |
IREB2 | GeneProduct | ENSG00000136381 (Ensembl Human) ![]() | |
IRP1 | GeneProduct | ENSG00000122729 (Ensembl Human) ![]() | |
MCOLN1 | GeneProduct | ENSG00000090674 (Ensembl Human) ![]() | |
SLC11A2 | GeneProduct | ENSG00000110911 (Ensembl Human) ![]() | |
SLC40A1 | GeneProduct | ENSG00000138449 (Ensembl Human) ![]() | |
STEAP3 | GeneProduct | ENSG00000115107 (Ensembl Human) ![]() | |
TF | Protein | ENSG00000091513 (Ensembl Human) ![]() | Transferrin |
TFR1 | Protein | ENSG00000072274 (Ensembl Human) ![]() | Transferrin receptor |
TFR2 | GeneProduct | ENSG00000106327 (Ensembl Human) ![]() | Transferrin receptor |
TfR1 RNA | Rna | ENSG00000072274 (Ensembl Human) ![]() | |
foetal HAMP? | Protein | ENSG00000105697 (Ensembl Human) ![]() | HAMP |
foetal TF | Protein | ENSG00000091513 (Ensembl Human) ![]() | Transferrin |
Annotated Interactions
No annotated interactions