Tryptophan metabolism (Mus musculus)
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2-Oxoadipate
Indolelactate
4-(2-Amino-5-hydroxyphenyl)
-2,4-dioxobutanoate
Formyl-5-hydroxykynurenamine
(Z)-5-Oxohex-2-enedioate
Indole-3-acetate
5-Hydroxy
-L-tryptophan
Isophenoxazine
Glycolysis / Gluconeogenesis
4-(2-Amino-3-hydroxyphenyl)
-2,4-dioxobutanoate
5-Hydroxyindoleacetylglycine
3-Methylindolepyruvate
Xanthurenic
Anthranilate
5-Methoxyindoleacetate
3-Hydroxykynurenamine
Quinolinate
Cinnavalininate
Glucobrassicin
N-Methyltryptamine
2-Formamino
benzoylacetate
Benzoate degradation via hydroxylation
2-Aminomuconate
5-Hydroxyindoleacetate
5-(2'-Formylethyl)-4,6-dihydroxypicolinate
N-Methylserotonin
Indole-3-acetaldoxime
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolin
Formyl-N-acetyl-5-
methoxykynurenamine
6-Hydroxyindolelactate
C00877
C01144
Formylanthranilate
Indolepyruvate
Benzoate degradation via hydroxylation
3-(2-Aminoethyl)
-1H-indol-5-ol
7,8-Dihydroxykynurenate
5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate
Anthranilate
Melatonin
3-Hydroxy-
L-kynurenine
5-Hydroxy-N-formylkynurenine
2-Amino-3-carboxymuconate
Indole-3-ethanol
Indole-3-acetaldehyde
C00527
4,8-Dihydroxyquinoline
6-Hydroxykynurenate
2-Formylaminobenzaldehyde
2,3-Dihydroxyindole
3-Hydroxyanthranilate
5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate
5-Hydroxykynurenamine
4,6-Dihydroxyquinoline
2-Oxoglutarate
8-Methoxykynurenate
3-Indoleglycolaldehyde
4-(2-Aminophenyl)-2,4-dioxobutanoate
N-Acetylindoxyl
Kynurenate
2-Aminomuconate
Nicotinate and nicotinamide metabolism
5-Hydroxyindolepyruvate
3-Methyldioxyindole
7,8-Dihydro-7,8-dihydroxykynurenate
C00332
L-Tryptophanyl-tRNA
PhenylAla, Tyr and Trp biosynthesis
3-Methoxyanthranilate
5-Hydroxyindoleacetaldehyde
Oxaloacetate
1.5.1.-
1.1.1.191
Maob
ASMT
Cyp2c55
Maob
Aldh1a2
Cyp7b1
Mdm2
5-Hydroxykynurenine
Aldh1a2
1.1.1.190
Tph1
Aldh3a2
Cyp2b15
3.5.1.49
Rnf25
CYP2A13
2-Aminophenol
5-Methoxytryptamine
ASMT
Rnf25
Ogdh
2.1.1.49
Aanat
1.1.1.110
Ube3a
Mdm2
3.5.1.4
Ddc
Kynu
Aldh1a1
Kynu
Aldh9a1
Afmid
Cyp2e1
Ido1
Cyp2a2
Prmt1
1.13.99.3
Cyp2d2
1.2.1.32
Indole-3-acetamide
Cyp1a2
Abp1
Gcdh
1.14.16.3
Dhcr24
L-Kynurenine
Formylkynurenine
Cyp4f14
1.13.11.10
Wars
Ido1
1.2.3.7
Ddc
Aldh2
4.1.1.43
4.1.99.1
2.1.1.47
3.5.5.1
1.4.3.2
Ddc
1.13.11.17
1.10.3.4
Ube3a
1.2.1.-
CYP3A4
Aadat
1.3.1.18
4.1.1.-
N-Acetylisatin
Cyp19a1
Acetyl-CoA
2.6.1.27
2.6.1.27
Kynu
3.5.1.9
Haao
Cyp1b1
Cyp2c12
Prmt1
Aldh1a1
Hadh
Ido1
3.2.1.147
6-Hydroxymelatonin
Aldh1a4
Prmt1
4.2.1.84
Aldh2
Acmsd
Aadat
Cyp2j6
2.6.1.27
1.13.11.23
Mdm2
Inmt
3.5.99.5
Maob
Aldh9a1
Gcdh
Cyp2f2
L-Tryptophan
Cyp1a1
Tryptamine
3-Indoleacetonitrile
Cat
1.14.13.9
Aox1
Acat1
Ubr5
1.13.12.3
1.14.99.2
1.13.11.-
Indole
Hsd17b10
Maob
Aldh1a4
1.14.16.-
Tdo2
Cyp2a1
Aldh3a2
Echs1
N-Acetylserotonin
1.7.3.2
Description
No description
Comments
GenMAPP notes
Converted from rat to human using ortholog information. Link to original KEGG map:
http://www.genome.ad.jp/dbget-bin/show
pathway?rno00380
GenMAPP remarks
Edited by Sebastien Burel
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP465(r30270)
with a 57% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
128037
view
18:00, 21 January 2024
Eweitz
Upgrade label to identified pathway, fix some truncated labels
104913
view
19:21, 24 June 2019
Khanspers
Modified description
104912
view
19:21, 24 June 2019
Khanspers
removed genmapp comments
104819
view
12:55, 19 June 2019
Fehrhart
Modified description
91016
view
07:21, 21 December 2016
Egonw
One more ChemSpider ID update.
91009
view
00:38, 21 December 2016
AlexanderPico
updated deprecated chemspider id
91008
view
17:51, 20 December 2016
AlexanderPico
updated deprecated chemspider id
79761
view
07:02, 10 April 2015
Egonw
Replaced an incorrectly KEGG Compound formatted identifier with a ChEBI identifier.
76163
view
15:21, 13 June 2014
Egonw
Added a few missing metabolite identifiers.
73389
view
16:57, 25 January 2014
Egonw
Added a bunch of missing metabolite identifiers.
73231
view
20:11, 12 January 2014
Egonw
Added a bunch of missing metabolite identifiers.
72319
view
07:39, 3 November 2013
Egonw
Added a few metabolite identifiers.
71752
view
20:20, 17 October 2013
MaintBot
Automated update of data sources
71178
view
14:19, 11 October 2013
Egonw
Added metabolite identifiers.
70995
view
15:19, 22 September 2013
Egonw
Added ChemSpider and ChEBI identifiers for metabolites.
69193
view
18:23, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67726
view
11:55, 26 June 2013
Ddigles
Ontology Term : 'tryptophan metabolic pathway' added !
54741
view
13:17, 8 December 2012
Egonw
Replaced multiple general nodes by Metabolite DataNode's.
47759
view
05:02, 6 April 2012
Khanspers
updated xrefs
47756
view
04:53, 6 April 2012
Khanspers
updated xrefs
41384
view
00:29, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34424
view
23:19, 9 December 2009
MaintBot
Automatic update of empty xrefs
33468
view
15:04, 30 November 2009
MaintBot
Removed group label
31518
view
21:39, 13 August 2009
MaintBot
Fixed text labels
30850
view
00:07, 30 July 2009
MaintBot
Converted from Homo sapiens
20845
view
11:30, 14 November 2008
MaintBot
[[Pathway:Mus musculus:Tryptophane Metabolism KEGG]] moved to [[Pathway:WP79]]: Moved to stable identifier
8466
view
13:46, 7 January 2008
MaintBot
[[Pathway:Mouse:Tryptophane Metabolism KEGG]] moved to [[Pathway:Mus musculus:Tryptophane Metabolism KEGG]]: Renaming species
7849
view
16:23, 18 December 2007
MaintBot
fixed category names
7408
view
12:42, 4 November 2007
MaintBot
Added categories to GPML
6506
view
22:19, 22 May 2007
L.M.Ferrante
gpml file for [[Mouse:Tryptophane_Metabolism_KEGG]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
(Z)-5-Oxohex-2-enedioate
Metabolite
(Z)-5-Oxohex-2-enedioate
1.1.1.110
GeneProduct
1.1.1.190
GeneProduct
1.1.1.191
GeneProduct
1.10.3.4
GeneProduct
1.13.11.-
GeneProduct
1.13.11.10
GeneProduct
1.13.11.17
GeneProduct
1.13.11.23
GeneProduct
1.13.12.3
GeneProduct
1.13.99.3
GeneProduct
1.14.13.9
GeneProduct
1.14.16.-
GeneProduct
1.14.16.3
GeneProduct
1.14.99.2
GeneProduct
1.2.1.-
GeneProduct
1.2.1.32
GeneProduct
1.2.3.7
GeneProduct
1.3.1.18
GeneProduct
1.4.3.2
GeneProduct
1.5.1.-
GeneProduct
1.7.3.2
GeneProduct
2,3-Dihydroxyindole
Metabolite
2-Amino-3-carboxymuconate
Metabolite
2-Amino-3-carboxymuconate
2-Aminomuconate
Metabolite
2-Aminomuconate
2-Aminophenol
Metabolite
2-Aminophenol
2-Formamino benzoylacetate
Metabolite
2-Formaminobenzoylacetate
2-Formylaminobenzaldehyde
Metabolite
2-Oxoadipate
Metabolite
2-Oxoadipate
2-Oxoglutarate
Metabolite
2-Oxoglutarate
2.1.1.47
GeneProduct
2.1.1.49
GeneProduct
2.6.1.27
GeneProduct
3-(2-Aminoethyl) -1H-indol-5-ol
Metabolite
3-(2-Aminoethyl)-1H-indol-5-ol
3-Hydroxy- L-kynurenine
Metabolite
3-Hydroxy-L-kynurenine
3-Hydroxyanthranilate
Metabolite
3-Hydroxyanthranilate
3-Hydroxykynurenamine
Metabolite
3-Hydroxykynurenamine
3-Indoleacetonitrile
Metabolite
3-Indoleacetonitrile
3-Indoleglycolaldehyde
Metabolite
3-Methoxyanthranilate
Metabolite
3-Methoxyanthranilate
3-Methyldioxyindole
Metabolite
3-Methylindolepyruvate
Metabolite
3-Methylindolepyruvate
3.2.1.147
GeneProduct
3.5.1.4
GeneProduct
3.5.1.49
GeneProduct
3.5.1.9
GeneProduct
3.5.5.1
GeneProduct
3.5.99.5
GeneProduct
4,6-Dihydroxyquinoline
Metabolite
4,6-Dihydroxyquinoline
4,8-Dihydroxyquinoline
Metabolite
4,8-Dihydroxyquinoline
4-(2-Amino-3-hydroxyphenyl) -2,4-dioxobutanoate
Metabolite
4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
4-(2-Amino-5-hydroxyphenyl) -2,4-dioxobutanoate
Metabolite
4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate
4-(2-Aminophenyl)-2,4-dioxobutanoate
Metabolite
4-(2-Aminophenyl)-2,4-dioxobutanoate
4.1.1.-
GeneProduct
4.1.1.43
GeneProduct
4.1.99.1
GeneProduct
4.2.1.84
GeneProduct
5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate
Metabolite
5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate
5-(2'-Formylethyl)-4,6-dihydroxypicolinate
Metabolite
5-(2'-Formylethyl)-4,6-dihydroxypicolinate
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolin
Metabolite
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate
5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate
Metabolite
5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate
5-Hydroxy -L-tryptophan
Metabolite
5-Hydroxy-L-tryptophan
5-Hydroxy-N-formylkynurenine
Metabolite
5-Hydroxy-N-formylkynurenine
5-Hydroxyindoleacetaldehyde
Metabolite
5-Hydroxyindoleacetaldehyde
5-Hydroxyindoleacetate
Metabolite
5-Hydroxyindoleacetate
5-Hydroxyindoleacetylglycine
Metabolite
5-Hydroxyindolepyruvate
Metabolite
5-Hydroxykynurenamine
Metabolite
5-Hydroxykynurenamine
5-Hydroxykynurenine
Metabolite
5-Methoxyindoleacetate
Metabolite
5-Methoxyindoleacetate
5-Methoxytryptamine
Metabolite
6-Hydroxyindolelactate
Metabolite
6-Hydroxyindolelactate
6-Hydroxykynurenate
Metabolite
6-Hydroxykynurenate
6-Hydroxymelatonin
Metabolite
7,8-Dihydro-7,8-dihydroxykynurenate
Metabolite
7,8-Dihydro-7,8-dihydroxykynurenate
7,8-Dihydroxykynurenate
Metabolite
7,8-Dihydroxykynurenate
8-Methoxykynurenate
Metabolite
8-Methoxykynurenate
ASMT
GeneProduct
107626 (Entrez Gene)
Aadat
GeneProduct
23923 (Entrez Gene)
Aanat
GeneProduct
11298 (Entrez Gene)
Abp1
GeneProduct
76507 (Entrez Gene)
Acat1
GeneProduct
110446 (Entrez Gene)
Acetyl-CoA
Metabolite
Acetyl-CoA
Acmsd
GeneProduct
266645 (Entrez Gene)
Afmid
GeneProduct
71562 (Entrez Gene)
Aldh1a1
GeneProduct
11668 (Entrez Gene)
Aldh1a2
GeneProduct
19378 (Entrez Gene)
Aldh1a4
GeneProduct
Aldh2
GeneProduct
11669 (Entrez Gene)
Aldh3a2
GeneProduct
11671 (Entrez Gene)
Aldh9a1
GeneProduct
56752 (Entrez Gene)
Anthranilate
Metabolite
Anthranilate
Aox1
GeneProduct
11761 (Entrez Gene)
C00332
Metabolite
Acetoacetyl-CoA
C00527
Metabolite
Glutaryl-CoA
C00877
Metabolite
Crotonoyl-CoA
C01144
Metabolite
(S)-3-Hydroxybutanoyl-CoA
CYP2A13
GeneProduct
CYP3A4
GeneProduct
Cat
GeneProduct
12359 (Entrez Gene)
Cinnavalininate
Metabolite
Cinnavalininate
Cyp19a1
GeneProduct
13075 (Entrez Gene)
Cyp1a1
GeneProduct
13076 (Entrez Gene)
Cyp1a2
GeneProduct
13077 (Entrez Gene)
Cyp1b1
GeneProduct
13078 (Entrez Gene)
Cyp2a1
GeneProduct
Cyp2a2
GeneProduct
Cyp2b15
GeneProduct
Cyp2c12
GeneProduct
Cyp2c55
GeneProduct
72082 (Entrez Gene)
Cyp2d2
GeneProduct
Cyp2e1
GeneProduct
13106 (Entrez Gene)
Cyp2f2
GeneProduct
13107 (Entrez Gene)
Cyp2j6
GeneProduct
13110 (Entrez Gene)
Cyp4f14
GeneProduct
64385 (Entrez Gene)
Cyp7b1
GeneProduct
13123 (Entrez Gene)
Ddc
GeneProduct
13195 (Entrez Gene)
Dhcr24
GeneProduct
74754 (Entrez Gene)
predicted
Echs1
GeneProduct
93747 (Entrez Gene)
Formyl-5-hydroxykynurenamine
Metabolite
Formyl-N-acetyl-5- methoxykynurenamine
Metabolite
Formyl-N-acetyl-5-methoxykynurenamine
Formylanthranilate
Metabolite
Formylanthranilate
Formylkynurenine
Metabolite
Formylkynurenine
Gcdh
GeneProduct
270076 (Entrez Gene)
predicted
Glucobrassicin
Metabolite
Glucobrassicin
Haao
GeneProduct
107766 (Entrez Gene)
Hadh
GeneProduct
15107 (Entrez Gene)
Hsd17b10
GeneProduct
15108 (Entrez Gene)
Ido1
GeneProduct
15930 (Entrez Gene)
Indole-3-acetaldehyde
Metabolite
Indole-3-acetaldehyde
Indole-3-acetaldoxime
Metabolite
Indole-3-acetaldoxime
Indole-3-acetamide
Metabolite
Indole-3-acetamide
Indole-3-acetate
Metabolite
Indole-3-acetate
Indole-3-ethanol
Metabolite
Indole
Metabolite
Indolelactate
Metabolite
Indolelactate
Indolepyruvate
Metabolite
Indolepyruvate
Inmt
GeneProduct
21743 (Entrez Gene)
Isophenoxazine
Metabolite
Isophenoxazine
Kynu
GeneProduct
70789 (Entrez Gene)
Kynurenate
Metabolite
4-Hydroxy-2-quinolinecarboxylic
L-Kynurenine
Metabolite
L-Kynurenine
L-Tryptophan
Metabolite
L-Tryptophanyl-tRNA
Metabolite
Maob
GeneProduct
109731 (Entrez Gene)
Mdm2
GeneProduct
17246 (Entrez Gene)
Melatonin
Metabolite
N-Acetylindoxyl
Metabolite
N-Acetylindoxyl
N-Acetylisatin
Metabolite
N-Acetylisatin
N-Acetylserotonin
Metabolite
N-Acetylserotonin
N-Methylserotonin
Metabolite
N-Methylserotonin
N-Methyltryptamine
Metabolite
N-Methyltryptamine
Ogdh
GeneProduct
18293 (Entrez Gene)
Oxaloacetate
Metabolite
Oxaloacetate
Prmt1
GeneProduct
15469 (Entrez Gene)
Quinolinate
Metabolite
Rnf25
GeneProduct
57751 (Entrez Gene)
Tdo2
GeneProduct
56720 (Entrez Gene)
Tph1
GeneProduct
21990 (Entrez Gene)
Tryptamine
Metabolite
Ube3a
GeneProduct
22215 (Entrez Gene)
Ubr5
GeneProduct
70790 (Entrez Gene)
Wars
GeneProduct
22375 (Entrez Gene)
Xanthurenic
Metabolite
Xanthurenic
Annotated Interactions
No annotated interactions
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DataNodes
Annotated Interactions
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