Vitamin B1 (thiamin) biosynthesis and salvage pathway (Zea mays)

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1 PlastidPeroxysome Mitochondriadegradation (including catalysis-induced)and repairor/and(4-amino-2-methylpyrimidin-5-yl)methyl phosphateATPhydroxymethylpyrimidine phosphate synthase (HMPPS)5-aminoimidazole ribotideGlycineGRMZM2G027663thiamine diphosphate transporterUNKNOWNNUDIX hydrolase(4-amino-2-methylpyrimidin-5-yl)methyl diphosphatehydroxymethylpyrimidine phosphate kinase ThiDNADadenylated thiazole carboxylatethiazole biosynthetic enzyme (Thi4)4-methyl-5-(2-hydroxyethyl)-thiazole phosphate (HET-P)hydrolase?thiamine monophosphatethiamine phosphate pyrophosphorylase (TMP-PPase)thiaminethiamine monophosphate phosphatase (ThMPase)nicotinamideThi4 enzymeAMPPO4H2OMet, 5'dAHCOOHCONAD(P)NAD(P)HSAMhydroxymethylpyrimidine kinase4-amino-5-phosphonooxymethyl-2-methylpyrimidineADPPPithiamine diphosphatethiamine diphosphatethiamine diphosphate transporterthiamine diphosphate transporterthiamine diphosphatethiamine diphosphatedegradation (including catalysis-induced)and repairthiamine degradation proteinthiamine transporter (?)thiamine monophosphatethiaminethiamine monophosphate phosphatase (ThMPase)thiamine diphosphatePO4H2Othiamine pyrophosphokinase (TPPK))ATP/GTPADP/GTPdegradation (including catalysis-induced)and repairthiamine degradation products transporter (?)thiamine monophosphate transporter (?)hydroxymethylpyrimidine (phosphate) [HMP(P)] transporter(4-amino-2-methylpyrimidin-5-yl)methylthiamin-triphosphatasethiamine triphosphatethiamine diphosphatethiamin-triphosphate synthaseUNKNOWNCOG0212UNKNOWNUNKNOWNhydroxyethylthiazole kinase4-methyl-5-(2-hydroxyethyl)thiazole (HET)4-methyl-5-(2-hydroxyethyl)-thiazole phosphate (HET-P)thiaminase II (TenA1)4-amino-2-methyl-5-aminomethylpyrmidine or others4-amino-5-phosphonooxymethyl-2-methylpyrimidinethiaminase II homolog (TenA2)thiamine diphosphate transporterthiamine transporter4-methyl-5-(2-hydroxyethyl)-thiazole transporterhydroxymethylpyrimidine (HMP) transporterthiamine4-methyl-5-(2-hydroxyethyl)-thiazolethiamine diphosphate(4-amino-2-methylpyrimidin-5-yl)methylGRMZM2G401934GRMZM2G018375GRMZM2G074097GRMZM2G055458GRMZM5G864815GRMZM2G094558GRMZM2G078283GRMZM2G148896GRMZM2G080501GRMZM2G031461GRMZM2G001904GRMZM2G118515GRMZM2G124911ADPATPGRMZM2G401934(4-amino-2-methylpyrimidin-5-yl)methyl phosphateInactive


Description

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Ontology Terms

 

Bibliography

  1. Gerdes S, Lerma-Ortiz C, Frelin O, Seaver SM, Henry CS, de Crécy-Lagard V, Hanson AD; ''''; , PubMed Europe PMC Scholia
  2. Chatterjee A, Abeydeera ND, Bale S, Pai PJ, Dorrestein PC, Russell DH, Ealick SE, Begley TP; ''Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase.''; Nature, 2011 PubMed Europe PMC Scholia
  3. Goyer, A; ''''; , PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
128528view14:52, 11 February 2024EweitzModified description
128527view14:50, 11 February 2024EweitzIncrease cell membrane line thickness; nearly invisible on site previously
128526view14:49, 11 February 2024EweitzIncrease text-background contrast for readability, economize layout
128525view14:47, 11 February 2024EweitzPad nodes for readability, standardize case
110987view14:56, 25 June 2020L DupuisConnected lines
107279view14:37, 17 September 2019MaintBotChEBI identifier normalization
89946view14:12, 6 October 2016MkutmonModified description
78450view10:27, 7 January 2015MaintBotadded missing graphIds
73524view23:37, 29 January 2014KhanspersModified title
72344view18:51, 10 November 2013AriuttaAdd identifiers matching specified data node labels
72343view18:31, 10 November 2013AriuttaPeriodical save, work in progress
72342view18:21, 10 November 2013AriuttaPeriodical save, work in progress
71903view17:54, 22 October 2013MaintBotRemoved source from datanodes with empty id
70253view21:38, 15 July 2013MaintBotupdated to 2013 schema
54920view05:07, 12 December 2012SvetaGModified description
54919view05:06, 12 December 2012SvetaGSpecify description
54918view05:03, 12 December 2012SvetaGSpecify description
54917view04:57, 12 December 2012SvetaGLiterature added
54916view04:50, 12 December 2012SvetaGModified description
54915view04:48, 12 December 2012SvetaGModified description
54910view23:47, 11 December 2012SvetaGEdited pathway
54909view23:45, 11 December 2012SvetaGPeriodical save, work in progress
54908view23:35, 11 December 2012SvetaGPeriodical save, work in progress
54907view23:25, 11 December 2012SvetaGPeriodical save, work in progress
54906view21:16, 11 December 2012SvetaGPeriodical save, work in progress
54905view21:06, 11 December 2012SvetaGPeriodical save, work in progress
54904view20:33, 11 December 2012SvetaGEdits
54903view20:20, 11 December 2012SvetaGPeriodical save, work in progress
54902view19:57, 11 December 2012SvetaGPeriodical save, work in progress
54901view19:47, 11 December 2012SvetaGPeriodical save, work in progress
54900view19:36, 11 December 2012SvetaGPeriodical save, work in progress
54899view19:16, 11 December 2012SvetaGPeriodical save, work in progress
54727view18:35, 7 December 2012SvetaGModified title
53368view00:29, 6 November 2012PjaiswalModified title
53367view00:29, 6 November 2012PjaiswalModified title
53105view01:08, 30 October 2012MaintBotModified categories
53027view23:55, 25 October 2012PjaiswalModified categories
53026view23:54, 25 October 2012PjaiswalOntology Term : 'vitamin and vitamin metabolites signaling pathway' added !
53025view23:54, 25 October 2012PjaiswalOntology Term : 'plant cell' added !
53024view23:53, 25 October 2012PjaiswalNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(4-amino-2-methylpyrimidin-5-yl)methyl diphosphateMetabolite16761 (ChEBI)
(4-amino-2-methylpyrimidin-5-yl)methyl phosphateMetabolite15422 (ChEBI)
(4-amino-2-methylpyrimidin-5-yl)methyl phosphateMetabolite18032 (ChEBI)
(4-amino-2-methylpyrimidin-5-yl)methylMetabolite16892 (ChEBI)
4-amino-2-methyl-5-aminomethylpyrmidine or othersMetabolite
4-amino-5-phosphonooxymethyl-2-methylpyrimidineMetabolite16892 (ChEBI)
4-methyl-5-(2-hydroxyethyl)-thiazole phosphate (HET-P)Metabolite
4-methyl-5-(2-hydroxyethyl)-thiazole transporterProtein
4-methyl-5-(2-hydroxyethyl)-thiazoleMetabolite9533 (ChEBI)
4-methyl-5-(2-hydroxyethyl)thiazole (HET)Metabolite
5-aminoimidazole ribotideMetabolite28843 (ChEBI)
ADPMetabolite
ADP/GTPMetabolite
AMPMetabolite
ATPMetabolite
ATP/GTPMetabolite
COMetabolite17245 (ChEBI)
COG0212GeneProduct
  • 5-formyltetrahydrofolate cycloligase paralog implicated in thiamin metabolism
  • Type your comment here
GRMZM2G001904GeneProductGRMZM2G001904 (Gramene Maize)
GRMZM2G018375GeneProductGRMZM2G018375 (Gramene Maize)
GRMZM2G027663GeneProductGRMZM2G027663 (Gramene Maize)
GRMZM2G031461GeneProductGRMZM2G031461 (Gramene Maize)
GRMZM2G055458GeneProductGRMZM2G055458 (Gramene Maize)
GRMZM2G074097GeneProductGRMZM2G074097 (Gramene Maize)
GRMZM2G078283GeneProductGRMZM2G078283 (Gramene Maize)
GRMZM2G080501GeneProductGRMZM2G080501 (Gramene Maize)
GRMZM2G094558GeneProductGRMZM2G094558 (Gramene Maize)
GRMZM2G118515GeneProductGRMZM2G118515 (Gramene Maize)
GRMZM2G124911GeneProductGRMZM2G124911 (Gramene Maize)
GRMZM2G148896GeneProductGRMZM2G148896 (Gramene Maize)
GRMZM2G401934GeneProductGRMZM2G401934 (Gramene Maize)
GRMZM5G864815GeneProductGRMZM5G864815 (Gramene Maize)
GlycineMetabolite
H2OMetabolite
HCOOHMetabolite30751 (ChEBI)
Met, 5'dAMetabolite
NAD(P)Metabolite25524 (ChEBI)
NAD(P)HMetabolite13392 (ChEBI)
NADMetabolite13389 (ChEBI)
NUDIX hydrolaseGeneProduct
PO4Metabolite
PPiMetabolite
SAMMetabolite15414 (ChEBI)
Thi4 enzymeMetaboliteinactivated by donation of H2S group during catalysis
UNKNOWNMetabolite
adenylated thiazole carboxylateMetabolite
hydrolase?GeneProduct
hydroxyethylthiazole kinaseGeneProduct2.7.1.50 (EC Number)
hydroxymethylpyrimidine (HMP) transporterProtein
hydroxymethylpyrimidine (phosphate) [HMP(P)] transporterProtein
hydroxymethylpyrimidine kinaseGeneProduct2.7.1.49 (EC Number)
hydroxymethylpyrimidine phosphate kinase ThiDGeneProduct2.7.4.7 (EC Number)
hydroxymethylpyrimidine phosphate synthase (HMPPS)GeneProduct
nicotinamideMetabolite17154 (ChEBI)
thiamin-triphosphataseGeneProduct3.6.1.28 (EC Number)
thiamin-triphosphate synthaseGeneProduct2.7.4.15 (EC Number)
thiaminase II (TenA1)GeneProduct3.5.99.2 (EC Number)
thiaminase II homolog (TenA2)GeneProduct3.5.99.2 (EC Number)
thiamine degradation products transporter (?)Protein
thiamine degradation proteinProtein
thiamine diphosphate transporterProtein
thiamine diphosphateMetabolite9532 (ChEBI)
thiamine monophosphate phosphatase (ThMPase)GeneProduct
thiamine monophosphate transporter (?)Protein
thiamine monophosphateMetabolite9533 (ChEBI)
thiamine phosphate pyrophosphorylase (TMP-PPase)GeneProduct2.5.1.3 (EC Number)
thiamine pyrophosphokinase (TPPK))GeneProduct2.7.6.2 (EC Number)
thiamine transporterProtein
thiamine transporter (?)Protein
thiamine triphosphateMetabolite
thiamineMetabolite26948 (ChEBI)
thiazole biosynthetic enzyme (Thi4)GeneProduct

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2341"
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