New Pathway (Homo sapiens)

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1, 332323ApoptosisProliferation2. Chemistry of QuercetinERBB2KEAP1ARNTTCDDCYP1A2RAF1DRELPHOxygenGeneProductCellular oxidative damageSuperoxideQuercetin(Anti-Oxidant)Xanthine Oxidase (XOD)HO-1O-semiquinoneO-quinoneQuercetin AglyconeARELipoxygenase (LOX)NADPH OxidaseQuercetin(Pro-oxidant)Hydrogen peroxideQuercetinD-GlucoseQuercetin67LRIGF-IR AhRMEKAhRAhRARNTAhRARNTCYP1A1CYP1B1TCDDAhRTCDDAHRRRASERKNRF2NRF2NRF2NRF2


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History

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CompareRevisionActionTimeUserComment
57658view18:48, 31 January 2013KhanspersDeleted pathway: test pathway
56295view16:16, 5 January 2013EgonwMarked quercetin as a metabolite.
55341view16:21, 13 December 2012BryanSpecify description
55335view16:13, 13 December 2012BryanPeriodical save, work in progress
55332view16:03, 13 December 2012BryanPeriodical save, work in progress
55328view15:53, 13 December 2012BryanPeriodical save, work in progress
55324view15:43, 13 December 2012BryanPeriodical save, work in progress
55319view15:33, 13 December 2012BryanPeriodical save, work in progress
55314view15:23, 13 December 2012BryanPeriodical save, work in progress
55307view15:12, 13 December 2012BryanPeriodical save, work in progress
55299view15:01, 13 December 2012BryanPeriodical save, work in progress
55292view14:51, 13 December 2012BryanPeriodical save, work in progress
55284view14:41, 13 December 2012BryanPeriodical save, work in progress
55277view14:31, 13 December 2012BryanPeriodical save, work in progress
55271view14:21, 13 December 2012BryanPeriodical save, work in progress
55263view14:09, 13 December 2012BryanPeriodical save, work in progress
55256view13:59, 13 December 2012BryanPeriodical save, work in progress
55248view13:49, 13 December 2012BryanPeriodical save, work in progress
55241view13:37, 13 December 2012BryanPeriodical save, work in progress
55233view13:27, 13 December 2012BryanPeriodical save, work in progress
55222view13:07, 13 December 2012BryanPeriodical save, work in progress
55211view12:46, 13 December 2012BryanPeriodical save, work in progress
55207view12:36, 13 December 2012BryanPeriodical save, work in progress
55204view12:26, 13 December 2012BryanPeriodical save, work in progress
55200view12:16, 13 December 2012BryanPeriodical save, work in progress
55196view12:05, 13 December 2012BryanPeriodical save, work in progress
55193view11:50, 13 December 2012BryanNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
67LRGeneProduct
AHRRGeneProductENSG00000063438 (Ensembl Human)
ARE
ARNTGeneProductENSG00000143437 (Ensembl Human)
AhRGeneProductENSG00000106546 (Ensembl)
CYP1A1GeneProductENSG00000140465 (Ensembl Human)
CYP1A2GeneProductENSG00000140505 (Ensembl Human)
CYP1B1GeneProductENSG00000138061 (Ensembl Human)
Cellular oxidative damage
D-GlucoseMetaboliteHMDB00122 (HMDB)
DRE
ERBB2GeneProductENSG00000141736 (Ensembl Human)
ERKGeneProductENSG00000100030 (Ensembl Human)
GeneProductGeneProduct5594 (Entrez Gene)
HO-1GeneProductENSG00000100292 (Ensembl Human)
Hydrogen peroxideMetaboliteHMDB03125 (HMDB)
IGF-IR GeneProduct
KEAP1GeneProductENSG00000079999 (Ensembl Human)
LPH
Lipoxygenase (LOX)Protein1.13.11.12 (EC Number)
MEKGeneProductENSG00000169032 (Ensembl Human)
NADPH OxidaseProtein1.6.3.1 (EC Number)
NRF2GeneProductENSG00000116044 (Ensembl Human)
O-quinoneMetabolite
O-semiquinoneMetabolite
OxygenMetaboliteHMDB01377 (HMDB)
Quercetin (Anti-Oxidant)5280343 (PubChem)
Quercetin (Pro-oxidant)5280343 (PubChem)
Quercetin 5280343 (PubChem)
Quercetin Aglycone
RAF1GeneProductENSG00000132155 (Ensembl Human)
RASGeneProductpf00071 (Pfam)
SuperoxideMetaboliteHMDB02168 (HMDB)
TCDD1746-01-6 (CAS)
Xanthine Oxidase (XOD)Protein1.17.3.2 (EC Number)

Annotated Interactions

No annotated interactions
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