Phase I biotransformations, non P450 (Canis familiaris)

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1OHOHOHHydrolysisOHNP_001003969.1Phosphoric acid estersamidesPhosphoric acid estersLIPAcarboxylic acid estersCES2amidesPON2_CANFAESDPON3carboxylic acid estersthio estersthio estersPON1NP_001003085.1


Description

This pathway lists several phase 1 biotransformations and their related enzymes. NOTE: This pathway is incomplete, reduction and oxidation enzymes are missing

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP136(r29886) with a 100% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Klaassen, C.D., Watkins III, J.B.; ''Casarett & Doull's Essentials of Toxicology''; , 2003

History

View all...
CompareRevisionActionTimeUserComment
107088view14:17, 17 September 2019MaintBotChEBI identifier normalization
88305view15:27, 1 August 2016FehrhartOntology Term : 'cytochrome P450-independent phase I biotransformation pathway' added !
73515view23:20, 29 January 2014KhanspersModified title
68545view22:31, 5 July 2013MaintBotUpdated to 2013 gpml schema
58846view23:34, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40702view21:51, 1 March 2011MaintBotRemoved redundant pathway information and comments
31761view12:06, 14 August 2009MaintBotFixed group labels
30709view22:52, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CES2GeneProductENSCAFG00000020391 (Ensembl)
ESDGeneProductENSCAFG00000004473 (Ensembl)
LIPAGeneProductENSCAFG00000015721 (Ensembl)
NP_001003085.1GeneProductENSCAFG00000009333 (Ensembl)
NP_001003969.1GeneProductENSCAFG00000009316 (Ensembl)
PON1GeneProductENSCAFG00000002114 (Ensembl)
PON2_CANFAGeneProductENSCAFG00000002123 (Ensembl)
PON3GeneProductENSCAFG00000002118 (Ensembl)
Phosphoric acid estersMetabolite
amidesMetabolite32988 (ChEBI)
carboxylic acid estersMetabolite
thio estersMetabolite

Annotated Interactions

No annotated interactions
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