NAD salvage pathway II (Escherichia coli)

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1-15NADPAdenosinetriphosphatenadR5'-nucleotidaseactivityNADPphosphatasePhosphateWaterNicotinamide ribotideNAD+diphosphataseactivityNADWaterHydrogen IonHydrogen IonAdenosinemonophosphateWaterPhosphateNicotinamideribosideNicotinamide ribotideHydrogen IonADPNADHydrogen IonAdenosinetriphosphatePyrophosphatenadR


Description

No description

Comments

 
source: http://biocyc.org/ECOLI/NEW-IMAGE?type=PATHWAY&object=NAD-BIOSYNTHESIS-II&detail-level=3

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Ontology Terms

 

Bibliography

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  1. Ostrowski EA, Woods RJ, Lenski RE; ''The genetic basis of parallel and divergent phenotypic responses in evolving populations of Escherichia coli.''; Proc Biol Sci, 2008 PubMed Europe PMC Scholia
  2. Kemmer G, Reilly TJ, Schmidt-Brauns J, Zlotnik GW, Green BA, Fiske MJ, Herbert M, Kraiss A, Schlör S, Smith A, Reidl J; ''NadN and e (P4) are essential for utilization of NAD and nicotinamide mononucleotide but not nicotinamide riboside in Haemophilus influenzae.''; J Bacteriol, 2001 PubMed Europe PMC Scholia
  3. Liu G, Foster J, Manlapaz-Ramos P, Olivera BM; ''Nucleoside salvage pathway for NAD biosynthesis in Salmonella typhimurium.''; J Bacteriol, 1982 PubMed Europe PMC Scholia
  4. MacInnes JI, Borr JD; ''The family Pasteurellaceae: modern approaches to taxonomy.''; Can J Vet Res, 1990 PubMed Europe PMC Scholia
  5. Lin SJ, Ford E, Haigis M, Liszt G, Guarente L; ''Calorie restriction extends yeast life span by lowering the level of NADH.''; Genes Dev, 2004 PubMed Europe PMC Scholia
  6. Kawai S, Murata K; ''Structure and function of NAD kinase and NADP phosphatase: key enzymes that regulate the intracellular balance of NAD(H) and NADP(H).''; Biosci Biotechnol Biochem, 2008 PubMed Europe PMC Scholia
  7. Lundquist R, Olivera BM; ''Pyridine nucleotide metabolism in Escherichia coli. I. Exponential growth.''; J Biol Chem, 1971 PubMed Europe PMC Scholia
  8. Raffaelli N, Lorenzi T, Mariani PL, Emanuelli M, Amici A, Ruggieri S, Magni G; ''The Escherichia coli NadR regulator is endowed with nicotinamide mononucleotide adenylyltransferase activity.''; J Bacteriol, 1999 PubMed Europe PMC Scholia
  9. Lin SJ, Guarente L; ''Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease.''; Curr Opin Cell Biol, 2003 PubMed Europe PMC Scholia
  10. Commichau FM, Stülke J; ''Trigger enzymes: bifunctional proteins active in metabolism and in controlling gene expression.''; Mol Microbiol, 2008 PubMed Europe PMC Scholia
  11. Tritz GJ, Chandler JL; ''Recognition of a gene involved in the regulation of nicotinamide adenine dinucleotide biosynthesis.''; J Bacteriol, 1973 PubMed Europe PMC Scholia
  12. Fukuda C, Kawai S, Murata K; ''NADP(H) phosphatase activities of archaeal inositol monophosphatase and eubacterial 3'-phosphoadenosine 5'-phosphate phosphatase.''; Appl Environ Microbiol, 2007 PubMed Europe PMC Scholia
  13. Gerasimova AV, Gelfand MS; ''Evolution of the NadR regulon in Enterobacteriaceae.''; J Bioinform Comput Biol, 2005 PubMed Europe PMC Scholia
  14. ROWEN JW, KORNBERG A; ''The phosphorolysis of nicotinamide riboside.''; J Biol Chem, 1951 PubMed Europe PMC Scholia
  15. Kurnasov OV, Polanuyer BM, Ananta S, Sloutsky R, Tam A, Gerdes SY, Osterman AL; ''Ribosylnicotinamide kinase domain of NadR protein: identification and implications in NAD biosynthesis.''; J Bacteriol, 2002 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
106100view12:00, 16 August 2019MaintBotHMDB identifier normalization
71964view23:56, 23 October 2013MaintBotremoved data source from nodes without identifier
62864view10:28, 3 May 2013CizarModified description
62650view07:41, 1 May 2013CizarSpecify description
62649view07:41, 1 May 2013CizarSpecify description
62648view07:40, 1 May 2013CizarSpecify description
62647view07:40, 1 May 2013CizarSpecify description
62267view22:22, 26 April 2013AlexanderPicoOntology Term : 'pyridine nucleotide biosynthetic pathway' added !
62266view22:21, 26 April 2013AlexanderPicoOntology Term : 'purine salvage pathway' added !
62249view21:49, 26 April 2013AlexanderPicoOntology Term : 'NAD biosynthetic pathway' added !
62246view21:45, 26 April 2013AlexanderPicoModified categories
62005view09:43, 23 April 2013CizarRecorrected a gene
62004view09:37, 23 April 2013Cizaradded and corrected some annotations
61953view07:39, 22 April 2013CizarGrouped metabolites and aligned them
61801view10:22, 19 April 2013CizarModified description
61800view10:04, 19 April 2013Cizaradded references
61796view09:51, 19 April 2013CizarNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
5'-nucleotidase activityGeneProductGO:0008253 (GeneOntology)
ADPMetaboliteHMDB01341 (HMDB)
Adenosine monophosphateMetaboliteHMDB00045 (HMDB)
Adenosine triphosphateMetaboliteHMDB00538 (HMDB)
Hydrogen IonMetaboliteHMDB59597 (HMDB)
NAD+

diphosphatase

activity		GeneProductGO:0000210 (GeneOntology)
NADMetaboliteHMDB00902 (HMDB)
NADP phosphataseGeneProduct
NADPMetaboliteHMDB00217 (HMDB)
Nicotinamide ribosideMetaboliteHMDB00855 (HMDB)
Nicotinamide ribotideMetaboliteHMDB00229 (HMDB)
PhosphateMetaboliteHMDB01429 (HMDB)
PyrophosphateMetaboliteHMDB00250 (HMDB)
WaterMetaboliteHMDB02111 (HMDB)
nadRGeneProductEBESCG00000001171 (Ensembl)

Annotated Interactions

No annotated interactions
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