Glucocorticoid metabolism (Rattus norvegicus)

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2HOCHSignalingCortol3*Pregnane-3,11,20-trioneHOOHCholesterolCH3=O=O3Progesterone DegradationHOProgesteroneSteroid Hormone=OGlucocorticoidsCortisoneCH17-a-OH-PregnenoloneOHCortisol18-Hydroxy-CorticosteroneO5b-Pregnan-18-al11b, 21-Dihydroxy-3,20-AldosteroneTo Androgen Synthesis3a,11b,21-Trihydroxy-20-Oxo-Pregnane 3,20-dione5b-Pregnan-18-alHO11-Deoxycortisol*From Cholersterol Biosynthesis3O3C5b-Pregnane-3,20-dione2Cortolone=O17-a-OH-Progesterone17a,21-Dihydroxy-5b-=O-OHHCHCOCHPregnanediolH11b,17a 21-Trihydroxy-5bCHUrocortisolHOOHOCCorticosteroneOHCGlucuronidesCCOHOH11-Deoxycorticosterone=O2C=Oand MetabolismHPregnenoloneCCO3a-OH-5b-Pregnane-20-oneOHOHOCHCHUrocortisone3B-OH-delta-Steroid DhCyp21a1Corticosterone 18-Monooxy3-Oxo-5b-Steroid Dh3B-OH-delta-Steroid DhCyp11a1RGD:708361Hsd11b2Cyp17a1Steroid delta-IsomeraseSteroid delta-IsomeraseCyp11b120b-Hydroxysteroid DhCortisone beta-reductaseCyp17a1(R)20-hydroxysteroid DhRGD:708361Hsd11b1


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
116969view10:27, 16 May 2021EweitzModified title
71794view20:33, 17 October 2013MaintBotAutomated update of data sources
71303view16:59, 17 October 2013MaintBotAutomated update of data sources
70648view19:22, 21 August 2013EgonwReduced the number of Labels for each compound name from 2 to 1.
70647view19:16, 21 August 2013EgonwConverted a number of Labels into DataNodes.
69414view19:01, 8 July 2013MaintBotUpdated to 2013 gpml schema
67285view10:31, 26 June 2013Christine ChichesterOntology Term : 'C21-steroid hormone biosynthetic pathway' added !
62849view05:05, 3 May 2013MaintBotUpdated UniProt data source
49013view11:47, 3 July 2012Ishida-kazuyaPeriodical save, work in progress
49010view08:28, 3 July 2012Ishida-kazuya120704_JSOT2
49009view08:26, 3 July 2012Ishida-kazuya120703_JSOT
41736view02:39, 2 March 2011MaintBotRemoved redundant pathway information and comments
21321view11:31, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Glucocorticoid Mineralocorticoid Metabolism]] moved to [[Pathway:WP305]]: Moved to stable identifier
8082view13:46, 7 January 2008MaintBot[[Pathway:Rat:Glucocorticoid Mineralocorticoid Metabolism]] moved to [[Pathway:Rattus norvegicus:Glucocorticoid Mineralocorticoid Metabolism]]: Renaming species
7663view16:08, 18 December 2007MaintBotfixed category names
7362view12:42, 4 November 2007MaintBotAdded categories to GPML
19476view22:20, 22 May 2007M.Liebermangpml file for [[Rat:Glucocorticoid_Mineralocorticoid_Metabolism]]
19475view22:20, 22 May 2007Bconklingpml file for [[Rat:Glucocorticoid_Mineralocorticoid_Metabolism]]
6550view22:20, 22 May 2007Nsalomonisgpml file for [[Rat:Glucocorticoid_Mineralocorticoid_Metabolism]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(R)20-hydroxysteroid DhGeneProduct1.1.1.53, similiar SP:2BHD STREX
20b-Hydroxysteroid DhGeneProduct1.1.1.53, similiar SP:2BHD STREX
3-Oxo-5b-Steroid DhGeneProduct
3B-OH-delta-Steroid DhGeneProduct
Corticosterone 18-MonooxyGeneProductEC number: 1.14.15.5
Cortisone beta-reductaseGeneProduct1.3.1.3
Cyp11a1GeneProduct29680 (Entrez Gene)
Cyp11b1GeneProduct24293 (Entrez Gene)
Cyp17a1GeneProduct25146 (Entrez Gene)
Cyp21a1GeneProduct24298 (Entrez Gene) Homologus to SwissProtID: CPS1 MOUSE
Hsd11b1GeneProduct25116 (Entrez Gene)
Hsd11b2GeneProduct25117 (Entrez Gene)
RGD:708361GeneProduct191574 (Entrez Gene)
Steroid delta-IsomeraseGeneProduct

Annotated Interactions

No annotated interactions

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