IL-7 signaling pathway (Bos taurus)

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AutophosphorylationCytoplasmInhibitionControlReceptorExtracellularMolecule in the pathwayReaction through unknown mechanisms/moleculesUbiquitinationGOProteolytic cleavageDeubiquitinationECGolgi apparatusDPhosphorylationDDProteins in a complex interactionPalmitoylationAcetylation(Protein-protein interaction)MitochondrionEnzyme complexMethylationGlycosylationDemethylationNUPMDeacetylationENActivationPlasma membraneDesumoylationMTMolecular associationRecruitmentSumoylationCYAccession Number: NetPath 19EndosomeDephosphorylationTranslocationLigandNucleusCBLPTK2BIRF1BAXLOC506618FOXO3STAT5AIL7RMCL1JAK3IL2RGMAP2K1MAPK1RB1MUC1CBLBAKT1MAP2K2STAT1CDK2CCND2PIK3R1MAPK3GSK3BFYNCCNA2SHC1STAT5BJAK1BADPIK3R1CDK4CLTCGene SymbolGRB2LYNSOS1STAT3BCL2L11RAF1HRASIRS2STAMIRS1BLKSTAM2


Description

No description

Comments

GenMAPP notes 
NetPath 19 – IL-7 Signaling Pathway


The annotation of immune signaling pathways (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use these pathways, you must cite these websites.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP205(r21111) with a 84% conversion rate.

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Ontology Terms

 

Bibliography

  1. Kandasamy K, Mohan SS, Raju R, Keerthikumar S, Kumar GS, Venugopal AK, Telikicherla D, Navarro JD, Mathivanan S, Pecquet C, Gollapudi SK, Tattikota SG, Mohan S, Padhukasahasram H, Subbannayya Y, Goel R, Jacob HK, Zhong J, Sekhar R, Nanjappa V, Balakrishnan L, Subbaiah R, Ramachandra YL, Rahiman BA, Prasad TS, Lin JX, Houtman JC, Desiderio S, Renauld JC, Constantinescu SN, Ohara O, Hirano T, Kubo M, Singh S, Khatri P, Draghici S, Bader GD, Sander C, Leonard WJ, Pandey A; ''NetPath: a public resource of curated signal transduction pathways.''; Genome Biol, 2010 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117547view11:16, 21 May 2021EweitzModified title
115962view08:28, 22 March 2021EgonwCopied the NetPath paper into the literature list
115952view07:18, 22 March 2021EgonwModified description
89853view12:21, 6 October 2016MkutmonModified description
80715view15:23, 30 June 2015Mkutmonhomology conversion
63469view17:19, 10 May 2013MaintBotUpdated to 2013 gpml schema
40605view19:34, 1 March 2011MaintBotRemoved redundant pathway information and comments
33842view00:32, 9 December 2009MaintBotAutomatic update of empty xrefs
30581view22:09, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct280991 (Entrez Gene)
BADGeneProduct615013 (Entrez Gene)
BAXGeneProduct785708 (Entrez Gene)
BCL2L11GeneProduct507390 (Entrez Gene)
BLKGeneProduct532587 (Entrez Gene)
CBLGeneProduct527418 (Entrez Gene)
CBLBGeneProduct525906 (Entrez Gene)
CCNA2GeneProduct281667 (Entrez Gene)
CCND2GeneProduct615414 (Entrez Gene)
CDK2GeneProduct519217 (Entrez Gene)
CDK4GeneProduct510618 (Entrez Gene)
CLTCGeneProduct281080 (Entrez Gene)
FOXO3GeneProduct535530 (Entrez Gene)
FYNGeneProduct527263 (Entrez Gene)
GRB2GeneProduct535298 (Entrez Gene)
GSK3BGeneProduct790875 (Entrez Gene)
Gene SymbolGeneProduct
HRASGeneProduct513012 (Entrez Gene)
IL2RGGeneProduct281862 (Entrez Gene)
IL7RGeneProduct521554 (Entrez Gene)
IRF1GeneProduct789216 (Entrez Gene)
IRS1GeneProduct538598 (Entrez Gene)
IRS2GeneProduct
JAK1GeneProduct537201 (Entrez Gene)
JAK3GeneProduct
LOC506618GeneProduct506618 (Entrez Gene)
LYNGeneProduct534996 (Entrez Gene)
MAP2K1GeneProduct533199 (Entrez Gene)
MAP2K2GeneProduct510434 (Entrez Gene)
MAPK1GeneProduct327672 (Entrez Gene)
MAPK3GeneProduct531391 (Entrez Gene)
MCL1GeneProduct788087 (Entrez Gene)
MUC1GeneProduct281333 (Entrez Gene)
PIK3R1GeneProduct282307 (Entrez Gene)
PTK2BGeneProduct541008 (Entrez Gene)
RAF1GeneProduct521196 (Entrez Gene)
RB1GeneProduct534712 (Entrez Gene)
SHC1GeneProduct507196 (Entrez Gene)
SOS1GeneProduct537682 (Entrez Gene)
STAM2GeneProduct538505 (Entrez Gene)
STAMGeneProduct512734 (Entrez Gene)
STAT1GeneProduct510814 (Entrez Gene)
STAT3GeneProduct508541 (Entrez Gene)
STAT5AGeneProduct282375 (Entrez Gene)
STAT5BGeneProduct282376 (Entrez Gene)

Annotated Interactions

No annotated interactions
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