Prostaglandin synthesis and regulation (Gallus gallus)
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prolactin
release
Cytoplasm
Cell Membrane
Phospholipids
Cortisone
Gq signaling
pathway
PG Synthases
Inactive Metabolites
ANXA8
CYP11A1
PTGER1
PRL
PTGER2
PLA2G4A
ANXA6
PTGDS
PGF2a
TBXAS1
EDNRA
PTGDR
EDNRB
Calcium
PTGIS
ANXA3
ANXA1
Progesterone
S100A10
TXA2
PTGS2
PTGER3
PGF2a
S100A6
Cortisol
HPGD
SCGB1A1
Prostaglandin H2
PGI2
ANXA4
PGE2
HSD11B2
HSD11B1
PTGER4
EDN1
Calcium
PTGIR
ANXA5
Arachidonic Acid
Cortisol
PTGS1
ANXA2
PTGFR
Description
No description
Comments
GenMAPP notes
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks
See note for more details
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP98(r20887)
with a 52% conversion rate.
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Bibliography
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History
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Compare
Revision
Action
Time
User
Comment
118055
view
10:36, 24 May 2021
Eweitz
Modified title
106112
view
12:01, 16 August 2019
MaintBot
HMDB identifier normalization
87609
view
08:54, 25 July 2016
Lindarieswijk
Ontology Term : 'prostaglandin biosynthetic pathway' added !
87607
view
08:54, 25 July 2016
Lindarieswijk
Ontology Term : 'prostaglandin signaling pathway' added !
74195
view
13:08, 4 April 2014
Egonw
Removed a data source where no ID was given.
68805
view
17:15, 8 July 2013
MaintBot
Updated to 2013 gpml schema
40938
view
22:52, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33867
view
17:48, 9 December 2009
MaintBot
Automatic update of empty xrefs
33450
view
15:00, 30 November 2009
MaintBot
Removed group label
31503
view
21:34, 13 August 2009
MaintBot
Fixed text labels
30336
view
20:48, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ANXA1
GeneProduct
404271 (Entrez Gene)
ANXA2
GeneProduct
396297 (Entrez Gene)
ANXA3
GeneProduct
ANXA4
GeneProduct
ANXA5
GeneProduct
428767 (Entrez Gene)
ANXA6
GeneProduct
395481 (Entrez Gene)
ANXA8
GeneProduct
Arachidonic Acid
Metabolite
CYP11A1
GeneProduct
414838 (Entrez Gene)
Calcium
Metabolite
HMDB00464 (HMDB)
Cortisol
Metabolite
EDN1
GeneProduct
420854 (Entrez Gene)
PMID: 1474344
EDNRA
GeneProduct
373908 (Entrez Gene)
EDNRB
GeneProduct
408082 (Entrez Gene)
HPGD
GeneProduct
422567 (Entrez Gene)
HSD11B1
GeneProduct
419861 (Entrez Gene)
HSD11B2
GeneProduct
PGE2
Metabolite
HMDB03175 (HMDB)
PGF2a
Metabolite
HMDB01139 (HMDB)
PGI2
Metabolite
HMDB01335 (HMDB)
PLA2G4A
GeneProduct
396394 (Entrez Gene)
PRL
GeneProduct
396453 (Entrez Gene)
PTGDR
GeneProduct
PTGDS
GeneProduct
374110 (Entrez Gene)
PTGER1
GeneProduct
PTGER2
GeneProduct
100034745 (Entrez Gene)
PTGER3
GeneProduct
429116 (Entrez Gene)
PTGER4
GeneProduct
427183 (Entrez Gene)
PTGFR
GeneProduct
424548 (Entrez Gene)
PTGIR
GeneProduct
PTGIS
GeneProduct
PTGS1
GeneProduct
427752 (Entrez Gene)
PTGS2
GeneProduct
396451 (Entrez Gene)
Progesterone
Metabolite
Prostaglandin H2
Metabolite
S100A10
GeneProduct
396506 (Entrez Gene)
PMID: 12962548 relationship with Annexin 2
S100A6
GeneProduct
373951 (Entrez Gene)
SCGB1A1
GeneProduct
PMID: 7615804, PMID: 3292559
TBXAS1
GeneProduct
418101 (Entrez Gene)
TXA2
Metabolite
HMDB01452 (HMDB)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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External references
DataNodes
Annotated Interactions
No annotated interactions